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Searching for up to 100 curated homologs for BWI76_RS08215 FitnessBrowser__Koxy:BWI76_RS08215 (266 a.a.)

Found high-coverage hits (≥70%) to 28 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GlmD / b0678 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Escherichia coli K-12 substr. MG1655 (see 28 papers)
nagB / P0A759 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Escherichia coli (strain K12) (see 27 papers)
NAGB_ECOLI / P0A759 Glucosamine-6-phosphate deaminase; GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase; EC 3.5.99.6 from Escherichia coli (strain K12) (see 3 papers)
NAGB_ECO57 / P0A760 Glucosamine-6-phosphate deaminase; GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase; EC 3.5.99.6 from Escherichia coli O157:H7 (see paper)
1deaA / P0A759 Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from escherichia coli at 2.1 angstroms resolution (see paper)
nagB / PDB|1CD5 GlcN6P deaminase; EC 3.5.99.6 from Escherichia coli K12 (see 14 papers)
    95% identity, 100% coverage of query (534 bits)

2wu1A Glucosamine-6-phosphate deaminase complexed with the allosteric activator n-acetyl-glucoamine-6-phosphate both in the active and allosteric sites.
    95% identity, 100% coverage of query (534 bits)

1horA Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from escherichia coli at 2.1 angstroms resolution
    95% identity, 100% coverage of query (534 bits)

1fqoA Glucosamine 6-phosphate deaminase complexed with the substrate of the reverse reaction fructose 6-phosphate (open form)
    95% identity, 100% coverage of query (534 bits)

5hj5B / Q9KKS5 Crystal structure of tertiary complex of glucosamine-6-phosphate deaminase from vibrio cholerae with beta-d-glucose-6-phosphate and fructose-6-phosphate
    80% identity, 100% coverage of query (464 bits)

CH_124073 putative glucosamine-6-phosphate deaminase from Magnaporthe grisea 70-15 (see 2 papers)
    61% identity, 97% coverage of query (345 bits)

GNPI1_MESAU / Q64422 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Mesocricetus auratus (Golden hamster) (see paper)
    62% identity, 97% coverage of query (342 bits)

GNPI1_BOVIN / A4FV08 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Bos taurus (Bovine) (see paper)
    62% identity, 97% coverage of query (342 bits)

E1C878 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Gallus gallus (see paper)
    60% identity, 97% coverage of query (340 bits)

GNPI1_MOUSE / O88958 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Mus musculus (Mouse) (see paper)
    61% identity, 97% coverage of query (340 bits)

3hn6A / O30564 Crystal structure of glucosamine-6-phosphate deaminase from borrelia burgdorferi
    61% identity, 98% coverage of query (339 bits)

GNPI1_HUMAN / P46926 Glucosamine-6-phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin; EC 3.5.99.6 from Homo sapiens (Human) (see 3 papers)
    61% identity, 97% coverage of query (338 bits)

1ne7A / P46926 Human glucosamine-6-phosphate deaminase isomerase at 1.75 a resolution complexed with n-acetyl-glucosamine-6-phosphate and 2-deoxy-2-amino- glucitol-6-phosphate (see paper)
    61% identity, 97% coverage of query (337 bits)

GNPI2_HUMAN / Q8TDQ7 Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate deaminase 2; GNPDA 2; GlcN6P deaminase 2; Glucosamine-6-phosphate isomerase SB52; EC 3.5.99.6 from Homo sapiens (Human) (see 2 papers)
Q8TDQ7 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Homo sapiens (see 2 papers)
    60% identity, 97% coverage of query (335 bits)

U5LXR4 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Gallus gallus (see paper)
    61% identity, 71% coverage of query (255 bits)

Shew_0815 Glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Shewanella loihica PV-4
    42% identity, 98% coverage of query (210 bits)

NAGB_STRCO / Q9K487 Glucosamine-6-phosphate deaminase; GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase; EC 3.5.99.6 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    46% identity, 83% coverage of query (204 bits)

NAGB_BACSU / O35000 Glucosamine-6-phosphate deaminase 1; GlcN6P deaminase 1; GNPDA 1; Glucosamine-6-phosphate isomerase 1; EC 3.5.99.6 from Bacillus subtilis (strain 168) (see 3 papers)
O35000 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Bacillus subtilis (see paper)
2bkvB / O35000 Structure and kinetics of a monomeric glucosamine-6-phosphate deaminase: missing link of the nagb superfamily (see paper)
    41% identity, 90% coverage of query (199 bits)

2bkxA Structure and kinetics of a monomeric glucosamine-6-phosphate deaminase: missing link of the nagb superfamily
    41% identity, 90% coverage of query (199 bits)

GAMA_BACSU / O31458 Glucosamine-6-phosphate deaminase 2; GlcN6P deaminase 2; GNPDA 2; Glucosamine-6-phosphate isomerase 2; EC 3.5.99.6 from Bacillus subtilis (strain 168) (see 3 papers)
    38% identity, 93% coverage of query (182 bits)

GPI1 / O97439 glucosamine 6-phosphate isomerase 1 (EC 3.5.99.6) from Giardia intestinalis (see 2 papers)
    42% identity, 74% coverage of query (179 bits)

CA265_RS21925 Glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Pedobacter sp. GW460-11-11-14-LB5
    39% identity, 86% coverage of query (159 bits)

2ri1A / Q8DV70 Crystal structure of glucosamine 6-phosphate deaminase (nagb) with glcn6p from s. Mutans (see paper)
    38% identity, 77% coverage of query (144 bits)

nagB / A3CLX4 glucosamine-6-phosphate deaminase subunit (EC 3.5.99.6) from Streptococcus sanguinis (strain SK36) (see 2 papers)
    34% identity, 93% coverage of query (144 bits)

A8YZR7 glucosamine-6-phosphate deaminase (EC 3.5.99.6) from Staphylococcus aureus (see paper)
    33% identity, 91% coverage of query (140 bits)

Build an alignment

Build an alignment for BWI76_RS08215 and 25 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

YraG / b3141 putative deaminase AgaI from Escherichia coli K-12 substr. MG1655 (see 6 papers)
AGAI_ECOLI / P42912 Putative deaminase AgaI; EC 3.5.99.- from Escherichia coli (strain K12) (see paper)
    27% identity, 88% coverage of query (80.5 bits)

YieK / b3718 putative glucosamine-6-phosphate deaminase YieK from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    26% identity, 89% coverage of query (67.4 bits)

6PGL3_ARATH / Q84WW2 6-phosphogluconolactonase 3, chloroplastic; 6PGL3; Protein EMBRYO DEFECTIVE 2024; EC 3.1.1.31 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q84WW2 6-phosphogluconolactonase (EC 3.1.1.31) from Arabidopsis thaliana (see paper)
    23% identity, 78% coverage of query (50.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory