Sites on a Tree

 

Searching for up to 100 curated homologs for BWI76_RS11245 FitnessBrowser__Koxy:BWI76_RS11245 (261 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PotC / b1124 spermidine preferential ABC transporter membrane subunit PotC (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
PotC / P0AFK6 spermidine preferential ABC transporter membrane subunit PotC (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTC_ECOLI / P0AFK6 Spermidine/putrescine transport system permease protein PotC from Escherichia coli (strain K12) (see paper)
TC 3.A.1.11.1 / P0AFK6 Spermidine/putrescine transport system permease protein PotC aka B1124, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 5 papers)
potC spermidine/putrescine ABC transporter, permease protein PotC from Escherichia coli K12 (see paper)
    96% identity, 99% coverage of query (476 bits)

G7SFQ8 ABC-type polyamine transporter (subunit 2/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    38% identity, 94% coverage of query (178 bits)

PotI / b0857 putrescine ABC transporter membrane subunit PotI (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
PotI / P0AFL1 putrescine ABC transporter membrane subunit PotI (EC 7.6.2.11) from Escherichia coli (strain K12) (see paper)
POTI_ECOLI / P0AFL1 Putrescine transport system permease protein PotI from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.11.2 / P0AFL1 PotI aka B0857, component of Putrescine porter from Escherichia coli (see 5 papers)
    41% identity, 93% coverage of query (176 bits)

TC 3.A.1.11.7 / Q97Q44 Spermidine/putrescine ABC transporter, permease protein, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    34% identity, 92% coverage of query (161 bits)

YdcV / b1443 putative ABC transporter membrane subunit YdcV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcV / P0AFR9 putative ABC transporter membrane subunit YdcV from Escherichia coli (strain K12) (see 4 papers)
YDCV_ECOLI / P0AFR9 Inner membrane ABC transporter permease protein YdcV from Escherichia coli (strain K12) (see 2 papers)
    30% identity, 93% coverage of query (101 bits)

TC 3.A.1.11.6 / Q1M7Q2 Putative spermidine/putrescine transport system ABC transporter permease component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    31% identity, 81% coverage of query (99.4 bits)

Build an alignment

Build an alignment for BWI76_RS11245 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.11.3 / Q44381 MotD, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    26% identity, 92% coverage of query (85.1 bits)

Dshi_0549 ABC transporter for Xylitol, permease component 2 from Dinoroseobacter shibae DFL-12
    30% identity, 82% coverage of query (82.0 bits)

TC 3.A.1.20.1 / O54371 BitE, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
    27% identity, 89% coverage of query (73.2 bits)

PHNV_SALTY / P96065 Putative 2-aminoethylphosphonate transport system permease protein PhnV from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.11.5 / P96065 PhnV aka STM0426, component of 2-aminoethyl phosphonate porter from Salmonella typhimurium (see 2 papers)
    26% identity, 92% coverage of query (70.5 bits)

TC 3.A.1.11.4 / O70071 ChtK, component of Chrysopine porter
    21% identity, 93% coverage of query (70.1 bits)

TC 3.A.1.1.24 / Q72KX4 Sugar transport system permease protein aka TT_C0326, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    24% identity, 80% coverage of query (62.4 bits)

CysU / b2424 sulfate/thiosulfate ABC transporter inner membrane subunit CysU (EC 7.3.2.3; EC 7.3.2.5) from Escherichia coli K-12 substr. MG1655 (see paper)
CysU / P16701 sulfate/thiosulfate ABC transporter inner membrane subunit CysU (EC 7.3.2.3; EC 7.3.2.5) from Escherichia coli (strain K12) (see paper)
CYST_ECOLI / P16701 Sulfate transport system permease protein CysT from Escherichia coli (strain K12) (see paper)
TC 3.A.1.6.1 / P16701 CysT aka CysU aka B2424, component of Sulfate/thiosulfate porter from Escherichia coli (see 6 papers)
    28% identity, 73% coverage of query (61.6 bits)

TC 3.A.1.8.2 / Q8TJ86 Molybdenum ABC transporter, permease protein, component of The molybdate/tungstate ABC transporter, ModABC. The trans-inhibited 3-d structure of ModABC, is available (3D31.A and 3D31.B)(Gerber et al., 2008) from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
    29% identity, 72% coverage of query (59.3 bits)

GANQ_BACSU / O07011 Galactooligosaccharides transport system permease protein GanQ from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.1.2 / O07011 Putative arabinogalactan oligomer transport system permease protein ganQ, component of The galactooligosaccharide (transports the di, tri and tetrasaccharides) uptake porter GanOPQ (GanSPQ; MalEFG) functioning with the energizing ATPase MsmX (see 3.A.1.1.26) from Bacillus subtilis (see 2 papers)
    25% identity, 83% coverage of query (58.5 bits)

TC 3.A.1.1.12 / Q9AI66 PalG, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
    26% identity, 76% coverage of query (58.2 bits)

PGA1_c27950 N-Acetyl-D-glucosamine ABC transport system, permease component 2 from Phaeobacter inhibens BS107
    24% identity, 92% coverage of query (56.2 bits)

WTPB_ARCFU / O30143 Molybdate/tungstate transport system permease protein WtpB from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
TC 3.A.1.6.8 / O30143 Molybdate/tungstate transport system permease protein WtpB, component of Molybdate/tungstate transport system, ModABC (WtpABC) (ModA binds to ModBC with high affinity (0.11%u03BCM) and dissociates slowly; the complex is destabilized by nucleotide and substrate binding from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
    30% identity, 80% coverage of query (55.5 bits)

TC 3.A.1.1.26 / O06991 MalG aka yvdI, component of The maltose porter, MdxEFG and MsmX from Bacillus subtilis (see 2 papers)
    24% identity, 79% coverage of query (52.4 bits)

Ac3H11_2065 glucose ABC transporter, permease component 2 from Acidovorax sp. GW101-3H11
    23% identity, 100% coverage of query (51.6 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory