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Searching for up to 100 curated homologs for BWI76_RS11495 FitnessBrowser__Koxy:BWI76_RS11495 (284 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
    76% identity, 100% coverage of query (442 bits)

4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
    76% identity, 99% coverage of query (438 bits)

YeaE / b1781 methylglyoxal reductase YeaE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yeaE / P76234 methylglyoxal reductase YeaE (EC 1.1.1.21) from Escherichia coli (strain K12) (see 3 papers)
    70% identity, 100% coverage of query (427 bits)

5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
    52% identity, 99% coverage of query (275 bits)

4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
    52% identity, 99% coverage of query (275 bits)

6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
    39% identity, 93% coverage of query (167 bits)

Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
    39% identity, 93% coverage of query (167 bits)

6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
    39% identity, 93% coverage of query (167 bits)

5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
    39% identity, 93% coverage of query (167 bits)

Q8TZM9 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus (see 2 papers)
    40% identity, 88% coverage of query (145 bits)

Q5JI09 alcohol dehydrogenase (EC 1.1.1.1) from Thermococcus kodakarensis (see paper)
    38% identity, 88% coverage of query (140 bits)

Build an alignment

Build an alignment for BWI76_RS11495 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
    28% identity, 92% coverage of query (115 bits)

GCY1 putative uncharacterized protein from Candida albicans (see paper)
    31% identity, 90% coverage of query (111 bits)

Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
    30% identity, 90% coverage of query (110 bits)

4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
    30% identity, 90% coverage of query (110 bits)

AK1BA_HUMAN / O60218 Aldo-keto reductase family 1 member B10; ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase; EC 1.1.1.300; EC 1.1.1.54 from Homo sapiens (Human) (see 7 papers)
O60218 aldose reductase (EC 1.1.1.21) from Homo sapiens (see 2 papers)
    30% identity, 90% coverage of query (110 bits)

4gq0A / O60218 Crystal structure of akr1b10 complexed with NADP+ and caffeic acid phenethyl ester
    30% identity, 90% coverage of query (110 bits)

4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
    30% identity, 90% coverage of query (110 bits)

1zuaX Crystal structure of akr1b10 complexed with NADP+ and tolrestat
    30% identity, 90% coverage of query (110 bits)

4jiiX Crystal structure of akr1b10 complexed with NADP+ and zopolrestat
    30% identity, 90% coverage of query (110 bits)

4jihA Crystal structure of akr1b10 complexed with NADP+ and epalrestat
    30% identity, 90% coverage of query (110 bits)

4gabA Human akr1b10 mutant v301l complexed with NADP+ and fidarestat
    30% identity, 90% coverage of query (110 bits)

4ga8A Human akr1b10 mutant v301l complexed with NADP+ and sorbinil
    30% identity, 90% coverage of query (110 bits)

4i5xA Crystal structure of akr1b10 complexed with NADP+ and flufenamic acid
    30% identity, 90% coverage of query (110 bits)

5m2fX Crystal structure of human akr1b10 complexed with NADP+ and the synthetic retinoid uvi2008
    30% identity, 90% coverage of query (110 bits)

5liyX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk204
    30% identity, 90% coverage of query (110 bits)

5lixX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk184
    30% identity, 90% coverage of query (110 bits)

5liwX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk319
    30% identity, 90% coverage of query (110 bits)

5liuX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor idd388
    30% identity, 90% coverage of query (110 bits)

5likX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk181
    30% identity, 90% coverage of query (110 bits)

4xzlX Crystal structure of human akr1b10 complexed with NADP+ and jf0049
    30% identity, 90% coverage of query (110 bits)

4wevX Crystal structure of human akr1b10 complexed with NADP+ and sulindac
    30% identity, 90% coverage of query (110 bits)

4iccX Crystal structure of human akr1b10 complexed with NADP+ and jf0064
    30% identity, 90% coverage of query (110 bits)

5y7nA Crystal structure of akr1b10 in complex with NADP+ and androst-4-ene- 3-beta-6-alpha-diol
    30% identity, 90% coverage of query (110 bits)

1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
    27% identity, 92% coverage of query (107 bits)

AK1A1_RAT / P51635 Aldo-keto reductase family 1 member A1; 3-DG-reducing enzyme; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Rattus norvegicus (Rat) (see 4 papers)
P51635 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Rattus norvegicus (see 2 papers)
    31% identity, 90% coverage of query (107 bits)

IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
    27% identity, 90% coverage of query (107 bits)

AK1BF_HUMAN / C9JRZ8 Aldo-keto reductase family 1 member B15; Estradiol 17-beta-dehydrogenase AKR1B15; Farnesol dehydrogenase; Testosterone 17beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.300; EC 1.1.1.54; EC 1.1.1.216; EC 1.1.1.64 from Homo sapiens (Human) (see 3 papers)
C9JRZ8 acetoacetyl-CoA reductase (EC 1.1.1.36); 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Homo sapiens (see paper)
    30% identity, 90% coverage of query (107 bits)

YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
    29% identity, 95% coverage of query (107 bits)

AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
    29% identity, 90% coverage of query (105 bits)

AK1A1_HUMAN / P14550 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Homo sapiens (Human) (see 4 papers)
    29% identity, 95% coverage of query (105 bits)

PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
    27% identity, 85% coverage of query (104 bits)

AKR1A1 / P50578 aldehyde reductase (EC 1.1.1.2) from Sus scrofa (see paper)
AK1A1_PIG / P50578 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Sus scrofa (Pig) (see paper)
P50578 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Sus scrofa (see 2 papers)
3fx4A / P50578 Porcine aldehyde reductase in ternary complex with inhibitor (see paper)
    31% identity, 90% coverage of query (104 bits)

3h4gA Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
    31% identity, 90% coverage of query (104 bits)

3cv7A Crystal structure of porcine aldehyde reductase ternary complex
    31% identity, 90% coverage of query (104 bits)

Q5DD64 aldose reductase (EC 1.1.1.21) from Schistosoma japonicum (see paper)
    28% identity, 90% coverage of query (103 bits)

1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
    29% identity, 94% coverage of query (103 bits)

PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
    29% identity, 94% coverage of query (103 bits)

Akr1a4 / Q9JII6 alcohol dehydrogenase [NADP+] (EC 1.1.1.19) from Mus musculus (see 4 papers)
AK1A1_MOUSE / Q9JII6 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Mus musculus (Mouse) (see 5 papers)
Q540D7 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Mus musculus (see paper)
Q9JII6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mus musculus (see paper)
    30% identity, 90% coverage of query (103 bits)

GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
    35% identity, 71% coverage of query (101 bits)

A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
    31% identity, 90% coverage of query (101 bits)

DkgA / b3012 methylglyoxal reductase DkgA (EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
dkgA / Q46857 methylglyoxal reductase DkgA (EC 1.1.1.21; EC 1.1.1.346) from Escherichia coli (strain K12) (see 9 papers)
Q46857 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Escherichia coli (see paper)
    29% identity, 95% coverage of query (99.4 bits)

A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    31% identity, 94% coverage of query (99.4 bits)

1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
    34% identity, 71% coverage of query (99.0 bits)

7bc1A / A9CEY6 Crystal structure of aldo-keto reductase from agrobacterium tumefaciens in a ternary complex with NADPH and glucose (see paper)
    30% identity, 85% coverage of query (97.8 bits)

P45377 Aldose reductase-related protein 2; AR; Aldehyde reductase; Fibroblast growth factor-regulated protein; Protein FR-1; EC 1.1.1.21 from Mus musculus (Mouse)
    31% identity, 90% coverage of query (96.7 bits)

smoB / A9CEY6 6-dehydroglucose reductase monomer (EC 1.1.1.432) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
DHGRD_AGRFC / A9CEY6 6-dehydroglucose reductase; SQ monooxygenase cluster protein B; EC 1.1.1.432 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
    29% identity, 85% coverage of query (96.3 bits)

1frbA Fr-1 protein/NADPH/zopolrestat complex
    31% identity, 90% coverage of query (96.3 bits)

AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
    26% identity, 87% coverage of query (95.9 bits)

E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
    31% identity, 90% coverage of query (95.5 bits)

ALKR4_ARATH / Q93ZN2 Probable aldo-keto reductase 4; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 94% coverage of query (95.1 bits)

M6PR / P92923 mannose 6-phosphate reductase (EC 1.1.1.224) from Apium graveolens (see paper)
P92923 mannose-6-phosphate 6-reductase (EC 1.1.1.224) from Apium graveolens (see paper)
    28% identity, 94% coverage of query (95.1 bits)

YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
    28% identity, 89% coverage of query (94.7 bits)

Y1669_ARATH / Q94A68 Uncharacterized oxidoreductase At1g06690, chloroplastic; EC 1.-.-.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    28% identity, 92% coverage of query (94.0 bits)

DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
    27% identity, 89% coverage of query (94.0 bits)

AKR1E2 / Q96JD6 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Homo sapiens (see 7 papers)
AKCL2_HUMAN / Q96JD6 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis aldo-keto reductase; htAKR; Testis-specific protein; hTSP; EC 1.1.1.263 from Homo sapiens (Human) (see 2 papers)
    26% identity, 89% coverage of query (93.6 bits)

akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
    30% identity, 95% coverage of query (93.6 bits)

3uzxB Crystal structure of 5beta-reductase (akr1d1) e120h mutant in complex with NADP+ and epiandrosterone
    28% identity, 93% coverage of query (93.6 bits)

3uzxA Crystal structure of 5beta-reductase (akr1d1) e120h mutant in complex with NADP+ and epiandrosterone
    28% identity, 93% coverage of query (93.6 bits)

yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
    33% identity, 82% coverage of query (93.2 bits)

3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
    33% identity, 82% coverage of query (93.2 bits)

BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
    28% identity, 90% coverage of query (93.2 bits)

4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
    29% identity, 90% coverage of query (92.8 bits)

PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
    29% identity, 90% coverage of query (92.8 bits)

7s5fB / A0A1U9WT24 Crystal structure of mannose-6-phosphate reductase from celery (apium graveolens) leaves with NADP+ and mannonic acid bound (see paper)
    27% identity, 94% coverage of query (92.0 bits)

GAR1 / Q3ZFI7 D-galacturonate reductase (EC 1.1.1.365) from Hypocrea jecorina (see paper)
GAR1_HYPJE / Q3ZFI7 D-galacturonate reductase; D-galacturonic acid reductase; EC 1.1.1.365 from Hypocrea jecorina (Trichoderma reesei) (see paper)
    25% identity, 95% coverage of query (90.9 bits)

AK1D1_HUMAN / P51857 Aldo-keto reductase family 1 member D1; 3-oxo-5-beta-steroid 4-dehydrogenase; Delta(4)-3-ketosteroid 5-beta-reductase; Delta(4)-3-oxosteroid 5-beta-reductase; EC 1.3.1.3 from Homo sapiens (Human) (see 8 papers)
P51857 DELTA4-3-oxosteroid 5beta-reductase (EC 1.3.1.3) from Homo sapiens (see 8 papers)
    28% identity, 93% coverage of query (90.5 bits)

3g1rB Crystal structure of human liver 5beta-reductase (akr1d1) in complex with NADP and finasteride. Resolution 1.70 a
    28% identity, 93% coverage of query (90.1 bits)

3dopB Crystal structure of 5beta-reductase (akr1d1) in complex with NADP+ and 5beta-dihydrotestosterone, resolution 2.00a
    28% identity, 93% coverage of query (90.1 bits)

3cotA Crystal structure of human liver delta(4)-3-ketosteroid 5beta- reductase (akr1d1) in complex with progesterone and NADP. Resolution: 2.03 a.
    28% identity, 93% coverage of query (90.1 bits)

3cmfA Crystal structure of human liver 5beta-reductase (akr1d1) in complex with NADP and cortisone. Resolution 1.90 a.
    28% identity, 93% coverage of query (90.1 bits)

3cavA Crystal structure of 5beta-reductase (akr1d1) in complex with NADP+ and 5beta-pregnan-3,20-dione
    28% identity, 93% coverage of query (90.1 bits)

3casA Crystal structure of 5beta-reductase (akr1d1) in complex with NADP+ and 4-androstenedione
    28% identity, 93% coverage of query (90.1 bits)

3caqA Crystal structure of 5beta-reductase (akr1d1) in complex with NADPH
    28% identity, 93% coverage of query (90.1 bits)

3buvA Crystal structure of human delta(4)-3-ketosteroid 5-beta-reductase in complex with NADP and hepes. Resolution: 1.35 a.
    28% identity, 93% coverage of query (90.1 bits)

3burA / P51857 Crystal structure of delta(4)-3-ketosteroid 5-beta-reductase in complex with NADP and testosterone. Resolution: 1.62 a. (see paper)
    28% identity, 93% coverage of query (90.1 bits)

Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    30% identity, 97% coverage of query (90.1 bits)

2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
    30% identity, 97% coverage of query (90.1 bits)

8hw0A / A0A6B8QIS5 The structure of akr6d1
    30% identity, 77% coverage of query (89.7 bits)

1vp5A / Q9X0A2 Crystal structure of 2,5-diketo-d-gluconic acid reductase (tm1009) from thermotoga maritima at 2.40 a resolution
    28% identity, 92% coverage of query (89.7 bits)

5az1A Crystal structure of aldo-keto reductase (akr2e5) complexed with nadph (see paper)
    29% identity, 90% coverage of query (89.4 bits)

4aubE The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate
    29% identity, 89% coverage of query (88.2 bits)

GCY1_YEAST / P14065 Glycerol 2-dehydrogenase (NADP(+)); Galactose-inducible crystallin-like protein 1; EC 1.1.1.156 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
    27% identity, 88% coverage of query (87.4 bits)

6hg6A / A0A1S8QGT2 Clostridium beijerinckii aldo-keto reductase cbei_3974 with NADPH (see paper)
    28% identity, 90% coverage of query (85.1 bits)

I3ACR_SCHPO / O13848 NAD/NADP-dependent indole-3-acetaldehyde reductase; AKR3C2; EC 1.1.1.190; EC 1.1.1.191 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
SPAC19G12.09 / RF|NP_594424.1 NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 from Schizosaccharomyces pombe (see 3 papers)
    30% identity, 84% coverage of query (85.1 bits)

AKR4C8 / O80944 aldo-keto reductase family 4 member C8 (EC 1.1.1.21; EC 1.1.1.210) from Arabidopsis thaliana (see paper)
AKRC8_ARATH / O80944 Aldo-keto reductase family 4 member C8; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 89% coverage of query (85.1 bits)

3h7rA / O80944 Crystal structure of the plant stress-response enzyme akr4c8 (see paper)
    27% identity, 89% coverage of query (84.7 bits)

ALDR_PIG / P80276 Aldo-keto reductase family 1 member B1; Aldehyde reductase; Aldose reductase; AR; EC 1.1.1.300; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.21 from Sus scrofa (Pig) (see paper)
    28% identity, 90% coverage of query (84.3 bits)

5ketA / A0A140CVV2 Structure of the aldo-keto reductase from coptotermes gestroi (see paper)
    25% identity, 93% coverage of query (84.0 bits)

1ekoA Pig aldose reductase complexed with idd384 inhibitor
    28% identity, 90% coverage of query (84.0 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory