Sites on a Tree

 

Searching for up to 100 curated homologs for BWI76_RS13080 FitnessBrowser__Koxy:BWI76_RS13080 (752 a.a.)

Found high-coverage hits (≥70%) to 51 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AMO_KLEM8 / P80695 Primary amine oxidase; Monamine oxidase; Tyramine oxidase; EC 1.4.3.21 from Klebsiella michiganensis (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686 / BUCSAV 143 / CCM 1901) (see paper)
    98% identity, 100% coverage of query (1527 bits)

MaoA / b1386 copper-containing amine oxidase (EC 1.4.3.21) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
tynA / P46883 copper-containing amine oxidase (EC 1.4.3.21) from Escherichia coli (strain K12) (see 17 papers)
AMO_ECOLI / P46883 Primary amine oxidase; 2-phenylethylamine oxidase; Copper amine oxidase; Tyramine oxidase; EC 1.4.3.21 from Escherichia coli (strain K12) (see 3 papers)
    87% identity, 100% coverage of query (1369 bits)

1oacB / P46883 Crystal structure of a quinoenzyme: copper amine oxidase of escherichia coli at 2 angstroems resolution (see paper)
    87% identity, 96% coverage of query (1325 bits)

2wgqA Zinc substituted e coli copper amine oxidase, a model for the precursor for 2,4,5-trihydroxyphenylalaninequinone formation
    88% identity, 96% coverage of query (1323 bits)

2w0qA E. Coli copper amine oxidase in complex with xenon
    87% identity, 95% coverage of query (1319 bits)

1d6yA Crystal structure of e. Coli copper-containing amine oxidase anaerobically reduced with beta-phenylethylamine and complexed with nitric oxide.
    87% identity, 95% coverage of query (1319 bits)

1d6uA Crystal structure of e. Coli amine oxidase anaerobically reduced with beta-phenylethylamine
    87% identity, 95% coverage of query (1319 bits)

CAOA2_ARATH / F4IAX0 Amine oxidase [copper-containing] alpha 2, peroxisomal; AtCuAO8; AtCuAOalpha2; EC 1.4.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
F4IAX0 primary-amine oxidase (EC 1.4.3.21) from Arabidopsis thaliana (see paper)
    32% identity, 84% coverage of query (325 bits)

maoxI / AAA22076.1 amine oxidase from Arthrobacter sp (see paper)
    33% identity, 83% coverage of query (322 bits)

maoII / AAA22074.1 methylamine oxidase from Arthrobacter sp (see paper)
    33% identity, 83% coverage of query (322 bits)

CAOG1_ARATH / Q8H1H9 Amine oxidase [copper-containing] gamma 1; AtCuAO1; AtCuAOgamma1; Copper amine oxidase 1; Primary amine oxidase 1; EC 1.4.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q8H1H9 primary-amine oxidase (EC 1.4.3.21) from Arabidopsis thaliana (see paper)
    32% identity, 84% coverage of query (314 bits)

CAOG2_ARATH / Q9M2B9 Amine oxidase [copper-containing] gamma 2; AtCuAOgamma2; EC 1.4.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    32% identity, 84% coverage of query (313 bits)

CAOA3_ARATH / F4IAX1 Amine oxidase [copper-containing] alpha 3, peroxisomal; AtCuAO2; AtCuAOalpha3; Copper amine oxidase 2; EC 1.4.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
F4IAX1 primary-amine oxidase (EC 1.4.3.21) from Arabidopsis thaliana (see paper)
    30% identity, 84% coverage of query (307 bits)

A1R2C3 primary-amine oxidase (EC 1.4.3.21) from Paenarthrobacter aurescens (see paper)
    31% identity, 85% coverage of query (300 bits)

Q59118 Histamine oxidase; Copper amine oxidase; EC 1.4.3.22 from Arthrobacter globiformis
    32% identity, 83% coverage of query (299 bits)

Build an alignment

Build an alignment for BWI76_RS13080 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

CUAOZ_ARATH / Q8L866 Amine oxidase [copper-containing] zeta, peroxisomal; AtCuAO1; AtCuAO3; AtCuAOzeta; Copper amine oxidase 3; EC 1.4.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8L866 primary-amine oxidase (EC 1.4.3.21) from Arabidopsis thaliana (see paper)
    29% identity, 86% coverage of query (281 bits)

AMO_PEA / Q43077 Primary amine oxidase; Amine oxidase [copper-containing]; EC 1.4.3.21 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
Q43077 primary-amine oxidase (EC 1.4.3.21) from Pisum sativum (see paper)
AAA62490.1 copper amine oxidase from Pisum sativum (see paper)
    30% identity, 83% coverage of query (281 bits)

1ksiA / Q43077 Crystal structure of a eukaryotic (pea seedling) copper-containing amine oxidase at 2.2a resolution (see paper)
    30% identity, 83% coverage of query (280 bits)

1w2zA Psao and xenon
    30% identity, 83% coverage of query (280 bits)

DAO1_TOBAC / A0A1S3XSG2 Diamine oxidase [copper-containing] 1, peroxisomal; NtDAO1; Copper methylamine oxidase; N-methylputrescine oxidase 2, peroxisomal; NtMPO2; EC 1.4.3.-; EC 1.4.3.21 from Nicotiana tabacum (Common tobacco) (see 3 papers)
    29% identity, 83% coverage of query (279 bits)

MPO1_TOBAC / A0A1S4BDC4 N-methylputrescine oxidase 1, peroxisomal; NtMPO1; Copper methylamine oxidase; EC 1.4.3.-; EC 1.4.3.21 from Nicotiana tabacum (Common tobacco) (see 4 papers)
    29% identity, 83% coverage of query (275 bits)

ATY35659.1 cadaverine oxidase from Lupinus angustifolius (see paper)
    29% identity, 83% coverage of query (272 bits)

PAOX_ARTGO / P46881 Phenylethylamine oxidase; Primary amine oxidase; EC 1.4.3.21 from Arthrobacter globiformis (see paper)
    29% identity, 83% coverage of query (261 bits)

8j6gA / P46881 Neutron structure of copper amine oxidase from arthrobacter globiformis anaerobically reduced by phenylethylamine at pd 9.0
    29% identity, 83% coverage of query (261 bits)

3wa2X High resolution crystal structure of copper amine oxidase from arthrobacter globiformis
    29% identity, 83% coverage of query (261 bits)

5zpnA Copper amine oxidase from arthrobacter globiformis anaerobically reduced by phenylethylamine at ph 8 at 288 k (1)
    29% identity, 83% coverage of query (261 bits)

3x3xA Copper amine oxidase from arthrobacter globiformis anaerobically reduced by phenylethylamine
    29% identity, 83% coverage of query (261 bits)

2cg1A Agao in complex with wc11b (ru-wire inhibitor, 11-carbon linker, data set b)
    29% identity, 83% coverage of query (261 bits)

2cg0A Agao in complex with wc9a (ru-wire inhibitor, 9-carbon linker, data set a)
    29% identity, 83% coverage of query (261 bits)

2cfwA Agao in complex with wc7a (ru-wire inhibitor, 7-carbon linker, data set a)
    29% identity, 83% coverage of query (261 bits)

2cflA Agao in complex with wc6b (ru-wire inhibitor, 6-carbon linker, data set b)
    29% identity, 83% coverage of query (261 bits)

2cfkA Agao in complex with wc5 (ru-wire inhibitor, 5-carbon linker)
    29% identity, 83% coverage of query (261 bits)

2bt3A Agao in complex with ruthenium-c4-wire at 1.73 angstroms
    29% identity, 83% coverage of query (261 bits)

1rjoA Agao + xe
    29% identity, 83% coverage of query (261 bits)

1iqxA Crystal structure of cobalt-substituted amine oxidase from arthrobacter globiformis
    29% identity, 83% coverage of query (261 bits)

Q9SW90 primary-amine oxidase (EC 1.4.3.21) from Euphorbia characias (see 2 papers)
    28% identity, 83% coverage of query (258 bits)

AO1 / O23349 copper-containing amine oxidase (EC 1.4.3.21; EC 1.4.3.10) from Arabidopsis thaliana (see paper)
AO1_ARATH / O23349 Primary amine oxidase 1; AtAO1; EC 1.4.3.21 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    29% identity, 84% coverage of query (254 bits)

A1RDD3 primary-amine oxidase (EC 1.4.3.21) from Paenarthrobacter aurescens (see paper)
    28% identity, 83% coverage of query (253 bits)

3t0uB / P12807 Hansenula polymorpha copper amine oxidase-1 in complex with cu(i) (see paper)
    30% identity, 84% coverage of query (245 bits)

AMO_PICAN / P12807 Peroxisomal primary amine oxidase; Copper amine oxidase; Methylamine oxidase; EC 1.4.3.21 from Pichia angusta (Yeast) (Hansenula polymorpha) (see 3 papers)
P12807 primary-amine oxidase (EC 1.4.3.21) from Ogataea angusta (see 4 papers)
    30% identity, 83% coverage of query (245 bits)

3sxxA Hansenula polymorpha copper amine oxidase-1 in complex with co(ii)
    30% identity, 84% coverage of query (245 bits)

4ev5A Crystal structure of copper amine oxidase-1 from hansenula polymorpha in complex with benzylamine
    30% identity, 84% coverage of query (245 bits)

4ev2A Crystal structure of copper amine oxidase-1 from hansenula polymorpha in complex with ethylamine
    30% identity, 84% coverage of query (245 bits)

1a2vA Copper amine oxidase from hansenula polymorpha
    30% identity, 84% coverage of query (245 bits)

1ekmA Crystal structure at 2.5 a resolution of zinc-substituted copper amine oxidase of hansenula polymorpha expressed in escherichia coli
    30% identity, 84% coverage of query (245 bits)

3nbbA Crystal structure of mutant y305f expressed in e. Coli in the copper amine oxidase from hansenula polymorpha
    30% identity, 84% coverage of query (244 bits)

CAO1_SCHPO / Q9P7F2 Copper amine oxidase 1; EC 1.4.3.21 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
cao1 / RF|NP_593985.1 copper amine oxidase Cao1; EC 1.4.3.- from Schizosaccharomyces pombe (see 3 papers)
    28% identity, 84% coverage of query (226 bits)

CAO2_SCHPO / O42890 Copper amine oxidase-like protein cao2; EC 1.4.3.21 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
    29% identity, 83% coverage of query (226 bits)

AMO2 likely peroxisomal copper amine oxidase genes from Candida albicans (see paper)
    28% identity, 83% coverage of query (222 bits)

3loyA Crystal structure of a copper-containing benzylamine oxidase from hansenula polymorpha (see paper)
    28% identity, 84% coverage of query (214 bits)

Q12556 diamine oxidase (EC 1.4.3.22) from Aspergillus niger (see 2 papers)
    28% identity, 84% coverage of query (203 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory