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Searching for up to 100 curated homologs for BWI76_RS13125 FitnessBrowser__Koxy:BWI76_RS13125 (473 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YdbU / b1395 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
paaH / P76083 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Escherichia coli (strain K12) (see 3 papers)
PAAH_ECOLI / P76083 3-hydroxyadipyl-CoA dehydrogenase; EC 1.1.1.- from Escherichia coli (strain K12) (see 4 papers)
    72% identity, 100% coverage of query (692 bits)

HP15_2693 3-hydroxyacyl-CoA dehydrogenase PaaC (EC 1.1.1.-) from Marinobacter adhaerens HP15
    46% identity, 99% coverage of query (405 bits)

dcaH / AAL09091.1 DcaH from Acinetobacter baylyi (see 11 papers)
    37% identity, 98% coverage of query (302 bits)

paaH2 / Q0KCM8 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
    36% identity, 98% coverage of query (281 bits)

Msed_0399 / A4YDS4 crotonyl-CoA hydratase/(S)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.150) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 3 papers)
A4YDS4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); short-chain-enoyl-CoA hydratase (EC 4.2.1.150) from Metallosphaera sedula (see 2 papers)
    34% identity, 75% coverage of query (183 bits)

Build an alignment

Build an alignment for BWI76_RS13125 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AIM1 / Q9ZPI6 peroxisomal fatty acid β-oxidation multifunctional protein AIM1 (EC 1.1.1.35; EC 4.2.1.17) from Arabidopsis thaliana (see 4 papers)
AIM1_ARATH / Q9ZPI6 Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1; Protein ABNORMAL INFLORESCENCE MERISTEM 1; AtAIM1; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    27% identity, 98% coverage of query (166 bits)

MFP_ORYSJ / Q8W1L6 Peroxisomal fatty acid beta-oxidation multifunctional protein; MFP; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Oryza sativa subsp. japonica (Rice) (see paper)
    26% identity, 97% coverage of query (144 bits)

3k6jA / O17762 Crystal structure of the dehydrogenase part of multifuctional enzyme 1 from c.Elegans
    25% identity, 92% coverage of query (142 bits)

HADHA / P40939 mitochondrial trifunctional enzyme α subunit (EC 1.1.1.35; EC 4.2.1.17; EC 1.1.1.211) from Homo sapiens (see 5 papers)
ECHA_HUMAN / P40939 Trifunctional enzyme subunit alpha, mitochondrial; 78 kDa gastrin-binding protein; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Homo sapiens (Human) (see 11 papers)
P40939 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211) from Homo sapiens (see 6 papers)
    26% identity, 98% coverage of query (139 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory