Searching for up to 100 curated homologs for BWI76_RS15025 FitnessBrowser__Koxy:BWI76_RS15025 (268 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.24.5 / Q9HT68 Probable TonB-dependent receptor, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    48% identity, 96% coverage of query (219 bits)

4qhqA / B4EA88 The structure of a nutrient binding protein from burkholderia cenocepacia bound to methionine
    45% identity, 88% coverage of query (197 bits)

4ib2A / A7AZY4 Crystal structure of a putative lipoprotein (rumgna_00858) from ruminococcus gnavus atcc 29149 at 1.76 a resolution
    41% identity, 91% coverage of query (180 bits)

METQ_BACSU / O32167 Methionine-binding lipoprotein MetQ from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32167 MetQ (R) (aka YusA), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
    41% identity, 88% coverage of query (164 bits)

MetQ / b0197 L-methionine/D-methionine ABC transporter membrane anchored binding protein (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
metQ / P28635 L-methionine/D-methionine ABC transporter membrane anchored binding protein (EC 7.4.2.11) from Escherichia coli (strain K12) (see 6 papers)
METQ_ECOLI / P28635 D-methionine-binding lipoprotein MetQ from Escherichia coli (strain K12) (see paper)
TC 3.A.1.24.1 / P28635 MetQ, D-methionine-binding lipoprotein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 4 papers)
metQ / GB|ABE05723.1 D-methionine-binding lipoprotein MetQ from Escherichia coli K12 (see 5 papers)
    42% identity, 84% coverage of query (162 bits)

4yahX / P28635 Crystal structure of the methionine binding protein, metq (see paper)
    42% identity, 84% coverage of query (161 bits)

3tqwA / Q83F42 Structure of a abc transporter, periplasmic substrate-binding protein from coxiella burnetii (see paper)
    40% identity, 88% coverage of query (160 bits)

1xs5A / O07950 The crystal structure of lipoprotein tp32 from treponema pallidum (see paper)
    36% identity, 87% coverage of query (156 bits)

NlpA / b3661 lipoprotein-28 from Escherichia coli K-12 substr. MG1655 (see 5 papers)
    37% identity, 85% coverage of query (148 bits)

P04846 Lipoprotein 28 from Escherichia coli (strain K12)
    37% identity, 85% coverage of query (148 bits)

3k2dA Crystal structure of immunogenic lipoprotein a from vibrio vulnificus (see paper)
    38% identity, 75% coverage of query (137 bits)

4oteB / Q186K7 Crystal structure of a putative lipoprotein (cd630_1653) from clostridium difficile 630 at 2.20 a resolution
    35% identity, 88% coverage of query (127 bits)

6jf1A / A0A0H2UN92 Crystal structure of the substrate binding protein of a methionine transporter from streptococcus pneumoniae (see paper)
    35% identity, 80% coverage of query (124 bits)

3gxaC / Q7BMQ8 Crystal structure of gna1946 (see paper)
    35% identity, 83% coverage of query (118 bits)

6dzxA Crystal structure of the n. Meningitides methionine-binding protein in its d-methionine bound conformation.
    36% identity, 80% coverage of query (117 bits)

TC 3.A.1.24.3 / Q8K8K9 AtmB, component of The methionine porter, AtmBDE from Streptococcus pyogenes serotype M3 (see 2 papers)
    33% identity, 88% coverage of query (107 bits)

4ntlA / Q82Z74 Crystal structure of a lipoprotein, yaec family (ef3198) from enterococcus faecalis v583 at 1.80 a resolution
    32% identity, 79% coverage of query (103 bits)

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Build an alignment for BWI76_RS15025 and 17 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 3.A.1.24.4 / Q8NSN1 ABC-type transporter, periplasmic component (ABC-type transport system, secreted lipoprotein component), component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum (see paper)
    26% identity, 82% coverage of query (82.0 bits)

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