Searching for up to 100 curated homologs for BWI76_RS16225 FitnessBrowser__Koxy:BWI76_RS16225 (460 a.a.)
Found high-coverage hits (≥70%) to 27 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YdgI / b1605 putative arginine:ornithine antiporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ARCD_ECOLI / P0AAE5 Putative arginine/ornithine antiporter from Escherichia coli (strain K12) (see paper)
88% identity, 100% coverage of query (814 bits)
AAXC_CHLPN / Q9Z6M8 Arginine/agmatine antiporter from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see paper)
TC 2.A.3.2.7 / Q9Z6M8 Arginine/agmatine antiporter from Chlamydia pneumoniae (see 4 papers)
40% identity, 98% coverage of query (342 bits)
ARCD_PSEAE / P18275 Arginine/ornithine antiporter; Arginine-ornithine exchanger from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
TC 2.A.3.2.3 / P18275 Arginine:ornithine antiporter from Pseudomonas aeruginosa (see 3 papers)
arcD / GB|AAG08555.1 arginine/ornithine antiporter from Pseudomonas aeruginosa (see 3 papers)
46% identity, 95% coverage of query (328 bits)
arcD / CAA04686.1 arginine /ornithine antiporter from Lactobacillus sakei (see 2 papers)
38% identity, 95% coverage of query (288 bits)
TC 2.A.3.2.4 / P35865 Lysine permease from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
lysI / RF|YP_225261.1 L-lysine transport protein from Corynebacterium glutamicum (see paper)
35% identity, 96% coverage of query (259 bits)
TC 2.A.3.2.11 / F2HL56 Arginine/Ornithine antiporter of 526 aas and 14 TMSs from Lactococcus lactis subsp. lactis (strain CV56)
33% identity, 99% coverage of query (258 bits)
ARCD1_LACLM / A2RNI5 Arginine/ornithine antiporter ArcD1; Arginine/ornithine exchanger from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
32% identity, 99% coverage of query (258 bits)
TC 2.A.3.2.10 / F2HL52 Arginine/Ornithine antiporter of 497 aas and 13 TMSs, ArcD2 from Lactococcus lactis subsp. lactis (strain CV56)
33% identity, 90% coverage of query (231 bits)
ARCD2_LACLM / A2RNI1 Arginine/ornithine antiporter ArcD2; Arginine/ornithine exchanger from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
32% identity, 90% coverage of query (227 bits)
Build an alignment for BWI76_RS16225 and 9 homologs with ≥ 30% identity
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3l1lA Structure of arg-bound escherichia coli adic
29% identity, 95% coverage of query (136 bits)
5j4nA / P60061 Crystal structure of the l-arginine/agmatine antiporter adic in complex with agmatine at 2.6 angstroem resolution (see paper)
29% identity, 95% coverage of query (135 bits)
YjdD / b4115 arginine:agmatine antiporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
adiC / P60061 arginine:agmatine antiporter from Escherichia coli (strain K12) (see 2 papers)
ADIC_ECOLI / P60061 Arginine/agmatine antiporter from Escherichia coli (strain K12) (see 6 papers)
ADIC_ECO57 / P60063 Arginine/agmatine antiporter from Escherichia coli O157:H7 (see 3 papers)
TC 2.A.3.2.5 / P60061 Homodimeric electrogenic arginine (Km=80μM):agmatine antiporter, AdiC, involved in extreme acid resistance (Fang et al., 2007; Gong et al., 2003; Iyer et al., 2003). A projection structure at 6.5 Å resolution has been published (Casagrande et al., 2008), and the 3.2 Å resolution X-ray structure was determined by Fang et al., 2009 and Gao et al., 2009 from Escherichia coli (see 6 papers)
adiC / GB|AAN45533.1 arginine/agmatine antiporter from Shigella flexneri (see 6 papers)
29% identity, 95% coverage of query (134 bits)
ADIC_SALTY / P60066 Arginine/agmatine antiporter from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
28% identity, 95% coverage of query (131 bits)
PotE / b0692 putrescine transporter PotE from Escherichia coli K-12 substr. MG1655 (see 13 papers)
potE / P0AAF1 putrescine transporter PotE from Escherichia coli (strain K12) (see 14 papers)
POTE_ECOLI / P0AAF1 Putrescine transporter PotE; Putrescine-proton symporter / putrescine-ornithine antiporter from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.3.2.1 / P0AAF1 Putrescine:ornithine antiporter for putrescine export; putrescine:H+ symporter for uptake from Escherichia coli (see 5 papers)
28% identity, 90% coverage of query (112 bits)
6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
23% identity, 93% coverage of query (82.8 bits)
CadB / b4132 lysine:cadaverine antiporter from Escherichia coli K-12 substr. MG1655 (see 10 papers)
CadB / P0AAE8 lysine:cadaverine antiporter from Escherichia coli (strain K12) (see 12 papers)
CADB_ECOLI / P0AAE8 Cadaverine/lysine antiporter from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.2.2 / P0AAE8 Cadaverine:lysine antiporter [Catalyzes cadaverine uptake via H+ symport (Km=21μM) and cadaverine export (Km=300 μM) via cadaverine:lysine antiport.] (Soksawatmaekhin et al., 2004). Modeling tools have been used to gain information about the structures and functions of CadB and PotE in E. coli from Escherichia coli (see 6 papers)
23% identity, 94% coverage of query (77.4 bits)
STET_BACSU / O34739 Serine/threonine exchanger SteT from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.8.12 / O34739 The Ser/Thr exchange transporter (SteT) (also transports aromatic amino acids with lower efficiency) (Reig et al., 2007). The substrate-bound state of SteT shows increased conformational flexibility and kinetic stability, enabling transport of substrate across the cell membrane (Bippes et al. 2009). TMS8 sculpts the substrate-binding site and undergoes conformational changes during the transport cycle of SteT (Bartoccioni et al., 2010). Mutations allow substrate binding but not translocation. Other mutations stabilize the protein and result in higher production levels from Bacillus subtilis (see 2 papers)
24% identity, 83% coverage of query (68.2 bits)
BPHYT_RS17540 L-aspartate/L-glutamate/L-glutamine:H+ symporter from Burkholderia phytofirmans PsJN
25% identity, 84% coverage of query (66.6 bits)
AIMA_BACSU / Q45577 Glutamate/serine transporter AimA; Amino acid importer A from Bacillus subtilis (strain 168) (see 2 papers)
26% identity, 70% coverage of query (65.5 bits)
GADC_LACLM / O30417 Glutamate/gamma-aminobutyrate antiporter; Glu/GABA antiporter from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 2.A.3.7.1 / O30417 Glutamate:γ-aminobutyrate antiporter of 477 aas and 12 TMSs, GadC from Lactococcus lactis (subsp. lactis) (Streptococcus lactis) (see 3 papers)
24% identity, 72% coverage of query (53.9 bits)
TC 2.A.3.9.2 / P39570 Spore germination protein B2 (BB) (amino acid [D-alanine and L-asparagine] receptor) from Bacillus subtilis (see 3 papers)
22% identity, 81% coverage of query (53.1 bits)
RR42_RS28305 L-threonine:H+ symporter from Cupriavidus basilensis FW507-4G11
23% identity, 72% coverage of query (53.1 bits)
YhfM / b3370 fructoselysine/psicoselysine transporter from Escherichia coli K-12 substr. MG1655 (see 4 papers)
frlA / P45539 fructoselysine/psicoselysine transporter from Escherichia coli (strain K12) (see 4 papers)
FRLA_ECOLI / P45539 Probable fructoselysine/psicoselysine transporter FrlA from Escherichia coli (strain K12) (see paper)
23% identity, 78% coverage of query (50.8 bits)
GADC_ECO57 / P58229 Glutamate/gamma-aminobutyrate antiporter; Glu/GABA antiporter from Escherichia coli O157:H7 (see paper)
26% identity, 70% coverage of query (48.1 bits)
GadC / b1492 L-glutamate:4-aminobutyrate antiporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gadC / P63235 L-glutamate:4-aminobutyrate antiporter from Escherichia coli (strain K12) (see 14 papers)
GADC_ECOLI / P63235 Glutamate/gamma-aminobutyrate antiporter; Glu/GABA antiporter; Extreme acid sensitivity protein from Escherichia coli (strain K12) (see 12 papers)
GADC_SHIFL / P63236 Glutamate/gamma-aminobutyrate antiporter; Glu/GABA antiporter from Shigella flexneri (see paper)
TC 2.A.3.7.3 / C8U8G2 Glutamate:GABA antiporter, GadC (YcaM). GadC, transports GABA/Glu only under acidic conditions, with no detectable activity at pH values higher than 6.5 (Ma et al., 2012). Ma et al. (2012) determined the crystal structure of GadC at 3.1 Å resolution under basic conditions. GadC, comprising 12 TMSs, exists in a closed state, with its carboxy-terminal domain serving as a plug to block an otherwise inward-open conformation. Structural and biochemical analyses revealed the essential transport residues, identified the transport path and suggested a transport mechanism involving the rigid-body rotation of a helical bundle for GadC and other amino acid antiporters from Escherichia coli O103:H2 (strain 12009 / EHEC) (see paper)
gadC extreme acid sensitivity protein XasA from Escherichia coli K12 (see 12 papers)
26% identity, 70% coverage of query (47.8 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
24% identity, 74% coverage of query (46.6 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
24% identity, 74% coverage of query (46.2 bits)
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Lawrence Berkeley National Laboratory