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Searching for up to 100 curated homologs for BWI76_RS16585 FitnessBrowser__Koxy:BWI76_RS16585 (541 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

B6E9W1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Enterobacter hormaechei (see paper)
    82% identity, 100% coverage of query (926 bits)

F5S1H2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Enterobacter hormaechei (see paper)
    82% identity, 100% coverage of query (925 bits)

D1CE96 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobaculum terrenum (see 4 papers)
    39% identity, 89% coverage of query (380 bits)

5x7uA / D1CE96 Trehalose synthase from thermobaculum terrenum (see paper)
    39% identity, 89% coverage of query (380 bits)

I3WCP4 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas sp. P8005 (see paper)
    38% identity, 98% coverage of query (368 bits)

Q88FN0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see 2 papers)
    39% identity, 90% coverage of query (358 bits)

A0A2Z4RCL2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see paper)
    36% identity, 98% coverage of query (353 bits)

A0A4S2BJW1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas stutzeri (see paper)
    36% identity, 98% coverage of query (352 bits)

Q6L2Z7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Picrophilus torridus (see 2 papers)
    34% identity, 98% coverage of query (350 bits)

Q1J0Z5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus geothermalis (see paper)
    36% identity, 100% coverage of query (346 bits)

B8YM30 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Paenarthrobacter aurescens (see 2 papers)
    36% identity, 90% coverage of query (343 bits)

A0A1I7MT66 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Micrococcus terreus (see paper)
    34% identity, 98% coverage of query (340 bits)

Q7WUI5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 2 papers)
    39% identity, 89% coverage of query (337 bits)

B1PK99 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Meiothermus ruber (see 4 papers)
    38% identity, 89% coverage of query (336 bits)

I3NX86 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 4 papers)
    37% identity, 90% coverage of query (336 bits)

Q9RST7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 2 papers)
    37% identity, 90% coverage of query (336 bits)

Q5SL15 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see paper)
    39% identity, 89% coverage of query (335 bits)

5gtwA / I3NX86 The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
    37% identity, 90% coverage of query (332 bits)

Q47SE5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobifida fusca (see paper)
    35% identity, 89% coverage of query (331 bits)

A0A1R4FYB1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Corynebacterium glutamicum (see 2 papers)
    34% identity, 98% coverage of query (327 bits)

O06458 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 3 papers)
    38% identity, 89% coverage of query (326 bits)

M1PA89 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Rhodococcus opacus (see paper)
    36% identity, 87% coverage of query (325 bits)

D1ABU6 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermomonospora curvata (see 2 papers)
    33% identity, 98% coverage of query (325 bits)

A8QX00 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Actinoplanes sp. (see paper)
    35% identity, 89% coverage of query (323 bits)

3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis
    35% identity, 90% coverage of query (319 bits)

3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    35% identity, 90% coverage of query (319 bits)

5ykbD / I3NX86 The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
    36% identity, 90% coverage of query (318 bits)

treS / A0R6E0 trehalose synthase subunit (EC 5.4.99.16) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see 4 papers)
TRES_MYCS2 / A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 6 papers)
A0R6E0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycolicibacterium smegmatis (see 3 papers)
    36% identity, 87% coverage of query (317 bits)

5jy7B / A0R6E0 Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
    36% identity, 87% coverage of query (317 bits)

3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    36% identity, 87% coverage of query (317 bits)

TRES_MYCTU / P9WQ19 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WQ19 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycobacterium tuberculosis (see paper)
    36% identity, 86% coverage of query (315 bits)

4lxfA Crystal structure of m. Tuberculosis tres (see paper)
    35% identity, 86% coverage of query (308 bits)

4lxfB Crystal structure of m. Tuberculosis tres (see paper)
    34% identity, 86% coverage of query (290 bits)

Build an alignment

Build an alignment for BWI76_RS16585 and 33 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

BAA11354.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    29% identity, 91% coverage of query (224 bits)

O16G1_BACSU / O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see 3 papers)
CAB15461.1 α-1,6-glucosidase (MalL;YvdL;BSU34560) (EC 3.2.1.10) (see protein)
    28% identity, 91% coverage of query (220 bits)

5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin
    28% identity, 91% coverage of query (219 bits)

4m56A The structure of wild-type mall from bacillus subtilis
    28% identity, 91% coverage of query (219 bits)

ACE77085.1 oligosaccharide-producing multifunctional amylase (OPMA) (EC 2.4.1.-) (see protein)
    28% identity, 91% coverage of query (218 bits)

7lv6B / O06994 The structure of mall mutant enzyme s536r from bacillus subtilis
    28% identity, 91% coverage of query (218 bits)

4mazA The structure of mall mutant enzyme v200s from bacillus subtilus
    28% identity, 91% coverage of query (218 bits)

Q9F4G4 oligo-1,6-glucosidase (EC 3.2.1.10) from Bacillus subtilis (see paper)
AAG23399.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    27% identity, 91% coverage of query (214 bits)

Q5FMB7 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Lactobacillus acidophilus (see paper)
AAV42157.1 oligo-α-1,6-glucosidase (LBA0264) (EC 3.2.1.10) (see protein)
    26% identity, 93% coverage of query (210 bits)

O16G_PARTM / P29094 Oligo-1,6-glucosidase; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase; EC 3.2.1.10 from Parageobacillus thermoglucosidasius (Geobacillus thermoglucosidasius) (see paper)
BAA01368.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    29% identity, 90% coverage of query (210 bits)

ABU54057.1 α-amylase (BMW-amylase) (EC 3.2.1.1) (see protein)
    28% identity, 95% coverage of query (209 bits)

4aieA / Q5FMB7 Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
    26% identity, 92% coverage of query (208 bits)

P20845 alpha-amylase (EC 3.2.1.1) from Priestia megaterium (see paper)
CAA30247.1 α-amylase (EC 3.2.1.1) (see protein)
    28% identity, 96% coverage of query (207 bits)

AAX84031.1 α-amylase (AmyF) (EC 3.2.1.1) (see protein)
    28% identity, 94% coverage of query (205 bits)

AAK28739.1 α-glucosidase (PalZ) (EC 3.2.1.20) (see protein)
    28% identity, 94% coverage of query (204 bits)

Q5SL12 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB8 (see paper)
BAD70304.1 α-glucosidase (TTHA0481) (EC 3.2.1.20) (see protein)
    30% identity, 91% coverage of query (203 bits)

AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) (see protein)
    30% identity, 91% coverage of query (203 bits)

C1DMP8 isomaltulose synthase (EC 5.4.99.11) from Azotobacter vinelandii (see paper)
    28% identity, 91% coverage of query (203 bits)

BAB18518.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    30% identity, 91% coverage of query (202 bits)

AAD50603.1 α-glucosidase (EC 3.2.1.20) (see protein)
    30% identity, 91% coverage of query (201 bits)

Shewana3_2311 Alpha-glucosidase (EC 3.2.1.20) from Shewanella sp. ANA-3
    29% identity, 92% coverage of query (201 bits)

AKA95141.1 α-glucosidase (TtAG) (EC 3.2.1.20) (see protein)
    29% identity, 91% coverage of query (198 bits)

8ibkA / A0A2Z5WH92 Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
    27% identity, 90% coverage of query (197 bits)

A1IHL0 alpha-glucosidase (EC 3.2.1.20) from Apis cerana japonica (see paper)
BAF44218.1 α-glucosidase I (JBgI) (EC 3.2.1.20) (see protein)
jbgI / BAF44218.1 alpha-glucosidase isozyme I from Apis cerana japonica (see paper)
    27% identity, 95% coverage of query (197 bits)

AAA25570.1 α-glucosidase (Agl) (EC 3.2.1.20) (see protein)
    27% identity, 93% coverage of query (197 bits)

AAB82328.1 α-glucosidase 2 (Mav2) (EC 3.2.1.20) (see protein)
    29% identity, 74% coverage of query (195 bits)

CAA02858.1 palatinase / trehalulose hydrolase (MutA) (EC 3.2.1.10|3.2.1.-) (see protein)
    29% identity, 90% coverage of query (195 bits)

A0A223KY92 alpha-amylase (EC 3.2.1.1) from Sutcliffiella cohnii (see paper)
    26% identity, 89% coverage of query (194 bits)

B5ABD8 isomaltulose synthase (EC 5.4.99.11) from Enterobacter sp. FMB-1 (see 3 papers)
    26% identity, 90% coverage of query (194 bits)

BAC87873.1 α-transglucosidase (XgtA) (EC 2.4.1.-) (see protein)
    31% identity, 83% coverage of query (194 bits)

5do8B / Q8YAE6 1.8 angstrom crystal structure of listeria monocytogenes lmo0184 alpha-1,6-glucosidase (see paper)
    25% identity, 92% coverage of query (193 bits)

BAL49684.1 α-glucosidase (AglA;HaG) (EC 3.2.1.20) (see protein)
    32% identity, 74% coverage of query (193 bits)

3wy1A / H3K096 Crystal structure of alpha-glucosidase (see paper)
    32% identity, 74% coverage of query (193 bits)

3wy2A Crystal structure of alpha-glucosidase in complex with glucose
    32% identity, 74% coverage of query (193 bits)

CAA60858.1 α-glucosidase (Agm2) (EC 3.2.1.20) (see protein)
    26% identity, 92% coverage of query (192 bits)

Q99040 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Streptococcus mutans serotype c (see paper)
    28% identity, 90% coverage of query (192 bits)

PGA1_c07890 cytoplasmic trehalase (AlgA) from Phaeobacter inhibens BS107
    30% identity, 96% coverage of query (192 bits)

BAE79634.1 dextran α-1,6-glucosidase (DexB;SmDG) (EC 3.2.1.70) (see protein)
    28% identity, 90% coverage of query (192 bits)

4wlcA / Q99040 Structure of dextran glucosidase with glucose (see paper)
    28% identity, 90% coverage of query (192 bits)

4h8vA / M1E1F6 Crystal structure of the trehalulose synthase mutb in complex with trehalulose
    26% identity, 91% coverage of query (192 bits)

CAA54266.1 α-glucosidase (EC 3.2.1.20) (see protein)
CAA54266.1 alpha-glucosidase from Bacillus sp. (see paper)
    27% identity, 89% coverage of query (192 bits)

2zidA Crystal structure of dextran glucosidase e236q complex with isomaltotriose
    28% identity, 90% coverage of query (192 bits)

2pwdA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor deoxynojirmycin
    26% identity, 91% coverage of query (192 bits)

2pwgA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor castanospermine
    26% identity, 91% coverage of query (192 bits)

2ze0A / Q33E90 Alpha-glucosidase gsj (see paper)
    31% identity, 74% coverage of query (191 bits)

Q2PS28 isomaltulose synthase (EC 5.4.99.11) from Paraburkholderia acidicola (see 3 papers)
    26% identity, 91% coverage of query (191 bits)

BAA00534.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    28% identity, 87% coverage of query (191 bits)

3wy4A Crystal structure of alpha-glucosidase mutant e271q in complex with maltose
    31% identity, 74% coverage of query (191 bits)

AAL07400.1 α-amylase / neopullulanase (Npl) (EC 3.2.1.1) (see protein)
    28% identity, 91% coverage of query (190 bits)

AAF71997.1 α-glucosidase (EC 3.2.1.20) (see protein)
    27% identity, 90% coverage of query (190 bits)

M1E1F3 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. (see paper)
    26% identity, 91% coverage of query (189 bits)

AAA26939.1 dextran α-1,6-glucosidase (DexB) (EC 3.2.1.70) (see protein)
    27% identity, 90% coverage of query (189 bits)

Q9ZAP8 neopullulanase (EC 3.2.1.135) from Paenibacillus polymyxa (see paper)
AAD05199.1 α-amylase (formerly neopullulanase) (EC 3.2.1.1) (see protein)
    28% identity, 91% coverage of query (189 bits)

4ha1A Mutb inactive double mutant d200a-d415n in complex with isomaltulose
    26% identity, 91% coverage of query (189 bits)

2pwfA Crystal structure of the mutb d200a mutant in complex with glucose
    26% identity, 91% coverage of query (189 bits)

AAB82327.1 α-glucosidase 1 (Mav1) (EC 3.2.1.20) (see protein)
    29% identity, 74% coverage of query (188 bits)

CAA55409.1 α-1,4-glucosidase (MalA) (EC 3.2.1.20) (see protein)
    25% identity, 90% coverage of query (188 bits)

Q65MI2 alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Bacillus licheniformis (see 2 papers)
AAU39732.1 trehalose-6-P hydrolase (TreA;BlTreA;BLi00797;BL03069) (EC 3.2.1.93) (see protein)
    27% identity, 90% coverage of query (186 bits)

5brpA / Q65MI2 Crystal structure of bacillus licheniformis trehalose-6-phosphate hydrolase (trea), mutant r201q, in complex with png (see paper)
    27% identity, 90% coverage of query (185 bits)

Q33E90 alpha-glucosidase (EC 3.2.1.20) from Geobacillus sp. HTA-462 (see paper)
BAE48285.1 α-glucosidase (Gsj) (EC 3.2.1.20) (see protein)
    29% identity, 74% coverage of query (184 bits)

Q8KR84 isomaltulose synthase (EC 5.4.99.11) from Klebsiella sp. LX3 (see paper)
    25% identity, 91% coverage of query (184 bits)

BAB59003.1 α-glucosidase / maltase (MalT;AO090038000234) (EC 3.2.1.20) (see protein)
    28% identity, 90% coverage of query (184 bits)

BAE86926.1 α-glucosidase I (Hbg1;HBG-I;Loc409889) (EC 3.2.1.20) (see protein)
    31% identity, 74% coverage of query (183 bits)

BAG86620.1 trehalose-6-phosphate hydrolase (TreC;KP1_0530) (EC 3.2.1.93) (see protein)
    26% identity, 87% coverage of query (181 bits)

BAA12704.1 α-glucosidase / exo-α-1,4-glucosidase (EC 3.2.1.20) (see protein)
    29% identity, 74% coverage of query (181 bits)

AAG31032.1 trehalose-6-phosphate hydrolase (TreA) (EC 3.2.1.93) (see protein)
    27% identity, 92% coverage of query (181 bits)

ADD81256.1 α-amylase (Aamy1) (EC 3.2.1.20) (see protein)
    32% identity, 74% coverage of query (181 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory