Searching for up to 100 curated homologs for BWI76_RS16775 FitnessBrowser__Koxy:BWI76_RS16775 (360 a.a.)
Found high-coverage hits (≥70%) to 18 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HcxB / b0801 hydroxycarboxylate dehydrogenase B (EC 1.1.1.237) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
hcxB / P30178 hydroxycarboxylate dehydrogenase B (EC 1.1.1.237) from Escherichia coli (strain K12) (see paper)
HCXB_ECOLI / P30178 Hydroxycarboxylate dehydrogenase B; 2-oxoglutarate reductase; Hydroxyphenylpyruvate reductase; Phenylpyruvate reductase; EC 1.1.1.-; EC 1.1.1.237 from Escherichia coli (strain K12) (see paper)
72% identity, 100% coverage of query (546 bits)
2g8yA / P30178 The structure of a putative malate/lactate dehydrogenase from e. Coli.
72% identity, 99% coverage of query (541 bits)
comC / Q58820 L-2-hydroxycarboxylate dehydrogenase (EC 1.1.1.337) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 4 papers)
COMC_METJA / Q58820 L-sulfolactate dehydrogenase; (R)-2-hydroxyacid dehydrogenase; (R)-sulfolactate dehydrogenase; L-2-hydroxycarboxylate dehydrogenase (NAD(+)); EC 1.1.1.337 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58820 L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337) from Methanocaldococcus jannaschii (see 3 papers)
2x06A / Q58820 Sulfolactate dehydrogenase from methanocaldococcus jannaschii (see paper)
33% identity, 93% coverage of query (174 bits)
MDH_METFV / P16142 Malate/(S)-sulfolactate dehydrogenase; EC 1.1.1.310; EC 1.1.1.37; EC 1.1.1.82 from Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S) (see paper)
P16142 L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337) from Methanothermus fervidus (see 2 papers)
30% identity, 93% coverage of query (166 bits)
A0A0U3EA38 L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337) from Methanobrevibacter millerae (see paper)
30% identity, 90% coverage of query (157 bits)
mdpE / A2SP37 tert-butoxymethanol dehydrogenase from Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) (see paper)
32% identity, 95% coverage of query (137 bits)
1z2iA / Q7CRW4 Crystal structure of agrobacterium tumefaciens malate dehydrogenase, new york structural genomics consortium
31% identity, 94% coverage of query (133 bits)
1vbiA / Q53W84 Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus hb8
31% identity, 95% coverage of query (132 bits)
1v9nA / O59028 Structure of malate dehydrogenase from pyrococcus horikoshii ot3
30% identity, 95% coverage of query (130 bits)
dhpC / D7PC15 1-hydroxy-2-phosphorylethylphosphonate dehydrogenase from Streptomyces luridus (see paper)
30% identity, 89% coverage of query (128 bits)
Build an alignment for BWI76_RS16775 and 10 homologs with ≥ 30% identity
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YlbC / b0517 ureidoglycolate dehydrogenase (EC 1.1.1.350) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
allD / P77555 ureidoglycolate dehydrogenase (EC 1.1.1.350) from Escherichia coli (strain K12) (see 2 papers)
ALLD_ECOLI / P77555 Ureidoglycolate dehydrogenase (NAD(+)); EC 1.1.1.350 from Escherichia coli (strain K12) (see 2 papers)
P77555 ureidoglycolate dehydrogenase (NAD+) (EC 1.1.1.350) from Escherichia coli (see paper)
27% identity, 92% coverage of query (115 bits)
4fjuA Crystal structure of ureidoglycolate dehydrogenase in ternary complex with nadh and glyoxylate (see paper)
27% identity, 92% coverage of query (115 bits)
PY2CR_PSEAE / Q9I492 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase; Pyr2C/Pip2C reductase; Delta(1)-pyrroline-(4S)-hydroxy-2-carboxylate reductase; Pyr4SH2C reductase; Proline ketimine reductase; EC 1.5.1.21; EC 1.5.1.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9I492 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Pseudomonas aeruginosa (see paper)
28% identity, 76% coverage of query (113 bits)
PY2CR_PSEF5 / Q4KGT8 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
34% identity, 74% coverage of query (112 bits)
PY2CR_AGRFC / Q7CVK1 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
30% identity, 75% coverage of query (103 bits)
1s20G / P37672 A novel NAD binding protein revealed by the crystal structure of e. Coli 2,3-diketogulonate reductase (yiak) northeast structural genomics consortium target er82 (see paper)
25% identity, 91% coverage of query (99.0 bits)
YiaK / b3575 2,3-diketo-L-gulonate reductase (EC 1.1.1.130) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yiaK / P37672 2,3-diketo-L-gulonate reductase (EC 1.1.1.130) from Escherichia coli (strain K12) (see 4 papers)
DLGD_ECOLI / P37672 2,3-diketo-L-gulonate reductase; 2,3-DKG reductase; 3-dehydro-L-gulonate 2-dehydrogenase; EC 1.1.1.130 from Escherichia coli (strain K12) (see 2 papers)
25% identity, 91% coverage of query (97.8 bits)
PY2CR_STAND / D7A0Y0 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; EC 1.5.1.49 from Starkeya novella (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIMB 10456) (see paper)
30% identity, 70% coverage of query (94.0 bits)
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Lawrence Berkeley National Laboratory