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Searching for up to 100 curated homologs for BWI76_RS17700 FitnessBrowser__Koxy:BWI76_RS17700 (582 a.a.)

Found high-coverage hits (≥70%) to 52 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Tre / b1197 periplasmic trehalase (EC 3.2.1.28) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
treA / P13482 periplasmic trehalase (EC 3.2.1.28) from Escherichia coli (strain K12) (see 11 papers)
TREA_ECOLI / P13482 Periplasmic trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; Tre37A; EC 3.2.1.28 from Escherichia coli (strain K12) (see 2 papers)
AAC74281.1 α,α-trehalase (periplasmic) (TreA;OsmA) (Tre37A) (EC 3.2.1.28) (see protein)
    76% identity, 97% coverage of query (904 bits)

2jjbA Family 37 trehalase from escherichia coli in complex with casuarine-6- o-alpha-glucopyranose
    80% identity, 88% coverage of query (873 bits)

2jg0A / P13482 Family 37 trehalase from escherichia coli in complex with 1- thiatrehazolin (see paper)
    80% identity, 88% coverage of query (869 bits)

2wynA Structure of family 37 trehalase from escherichia coli in complex with a casuarine-6-o-a-d-glucoside analogue
    80% identity, 88% coverage of query (862 bits)

5z66A Structure of periplasmic trehalase from diamondback moth gut bacteria complexed with validoxylamine (see paper)
    82% identity, 87% coverage of query (861 bits)

2jf4A Family 37 trehalase from escherichia coli in complex with validoxylamine
    79% identity, 88% coverage of query (854 bits)

AO356_24205 Alpha,alpha-trehalase (EC 3.2.1.28) from Pseudomonas fluorescens FW300-N2C3
    57% identity, 84% coverage of query (569 bits)

Q3BXX2 alpha,alpha-trehalase (EC 3.2.1.28) from Xanthomonas campestris (see paper)
    53% identity, 91% coverage of query (545 bits)

Q63MI6 alpha,alpha-trehalase (EC 3.2.1.28) from Burkholderia pseudomallei (see paper)
    56% identity, 85% coverage of query (545 bits)

TreF / b3519 cytoplasmic trehalase (EC 3.2.1.28) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
treF / P62601 cytoplasmic trehalase (EC 3.2.1.28) from Escherichia coli (strain K12) (see 3 papers)
TREF_ECOLI / P62601 Cytoplasmic trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Escherichia coli (strain K12) (see paper)
AAC76544.1 trehalase (TreF;b3519) (EC 3.2.1.28) (see protein)
    52% identity, 83% coverage of query (515 bits)

D4I261 alpha,alpha-trehalase (EC 3.2.1.28) from Erwinia amylovora (see paper)
    50% identity, 83% coverage of query (493 bits)

P32358 alpha,alpha-trehalase (EC 3.2.1.28) from Bombyx mori (see paper)
BAA02909.1 trehalase (Treh1) (EC 3.2.1.28) (see protein)
    33% identity, 93% coverage of query (290 bits)

Q9XEY7 alpha,alpha-trehalase (EC 3.2.1.28) from Glycine max (see paper)
AAD22970.1 trehalase 1 (Tre1) (EC 3.2.1.28) (see protein)
    37% identity, 76% coverage of query (288 bits)

A0A2S1WCH9 alpha,alpha-trehalase (EC 3.2.1.28) from Holothuria leucospilota (see paper)
    34% identity, 89% coverage of query (284 bits)

D2KHJ0 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera litura (see paper)
    32% identity, 90% coverage of query (281 bits)

LOC410795 / A8J4S9 trehalase (bound form) (EC 3.2.1.28) from Apis mellifera (see 3 papers)
TREA_APIME / A8J4S9 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Apis mellifera (Honeybee) (see 2 papers)
A8J4S9 alpha,alpha-trehalase (EC 3.2.1.28) from Apis mellifera (see 2 papers)
BAF81545.1 α,α-trehalase (EC 3.2.1.28) (see protein)
BAF81545.1 trehalase from Apis mellifera (see paper)
    34% identity, 91% coverage of query (281 bits)

Q0ZIF5 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera frugiperda (see 2 papers)
ABE27189.1 trehalase (SfTre1) (soluble; midgut) (EC 3.2.1.28) (see protein)
    31% identity, 90% coverage of query (278 bits)

AGO32658.1 trehalase (Tre1;TmTre1) (soluble; midgut) (EC 3.2.1.28) (see protein)
    33% identity, 89% coverage of query (277 bits)

A6MIZ4 alpha,alpha-trehalase (EC 3.2.1.28) from Physcomitrium patens (see paper)
    37% identity, 72% coverage of query (277 bits)

TREA_RABIT / P19813 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Oryctolagus cuniculus (Rabbit) (see paper)
AAA63460.1 trehalase (TreH;TreA) (EC 3.2.1.28) (see protein)
    33% identity, 86% coverage of query (274 bits)

Q9W2M2 alpha,alpha-trehalase (EC 3.2.1.28) from Drosophila melanogaster (see paper)
    34% identity, 86% coverage of query (271 bits)

Q9W2M2 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Drosophila melanogaster (Fruit fly)
    34% identity, 86% coverage of query (271 bits)

B0M0J3 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera exigua (see paper)
ABY86218.1 trehalase-1 (Tre-1;SeTre-1) (EC 3.2.1.28) (see protein)
    31% identity, 91% coverage of query (270 bits)

C0LZJ7 alpha,alpha-trehalase (EC 3.2.1.28) from Nilaparvata lugens (see paper)
    34% identity, 87% coverage of query (269 bits)

Q9GYK9 alpha,alpha-trehalase (EC 3.2.1.28) from Caenorhabditis elegans (see paper)
    33% identity, 86% coverage of query (268 bits)

P32359 alpha,alpha-trehalase (EC 3.2.1.28) from Tenebrio molitor (see paper)
BAA01951.1 trehalase (EC 3.2.1.28) (see protein)
    31% identity, 90% coverage of query (266 bits)

A0A0F6PB63 alpha,alpha-trehalase (EC 3.2.1.28) from Helicoverpa armigera (see paper)
    32% identity, 86% coverage of query (266 bits)

TREA_HUMAN / O43280 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Homo sapiens (Human) (see 3 papers)
O43280 alpha,alpha-trehalase (EC 3.2.1.28) from Homo sapiens (see paper)
    34% identity, 86% coverage of query (265 bits)

ABO20846.1 trehalase 1 (Treh-1) (EC 3.2.1.28) (see protein)
    32% identity, 86% coverage of query (265 bits)

Q3MV18 alpha,alpha-trehalase (EC 3.2.1.28) from Bombyx mori (see paper)
BAE45249.1 trehalase 2 (Treh2;Treh-2) (EC 3.2.1.28) (see protein)
    33% identity, 88% coverage of query (263 bits)

AGL34007.2 membrane-bound trehalase (ALTre-2) (EC 3.2.1.28) (see protein)
    34% identity, 88% coverage of query (261 bits)

BAA24381.1 trehalase (TreA;TreH) (EC 3.2.1.28) (see protein)
    34% identity, 86% coverage of query (261 bits)

D2KWM9 alpha,alpha-trehalase (EC 3.2.1.28) from Nicotiana tabacum (see paper)
    36% identity, 71% coverage of query (260 bits)

TRE1_ARATH / Q9SU50 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; Trehalase 1; AtTRE1; EC 3.2.1.28 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9SU50 alpha,alpha-trehalase (EC 3.2.1.28) from Arabidopsis thaliana (see paper)
CAB51647.1 trehalase (AtTre1;At4g24040/T19F6.30) (plasma membrane-bound) (EC 3.2.1.28) (see protein)
    37% identity, 71% coverage of query (257 bits)

Q9JLT2 alpha,alpha-trehalase (EC 3.2.1.28) from Mus musculus (see 2 papers)
AAF61430.1 trehalase (EC 3.2.1.28) (see protein)
    33% identity, 86% coverage of query (256 bits)

A7XZC0 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera exigua (see paper)
ABU95354.1 trehalase 2 (Tre-2;Treh-2;SeTre-2) (EC 3.2.1.28) (see protein)
    33% identity, 88% coverage of query (256 bits)

B5ATV4 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera frugiperda (see 2 papers)
ACF94698.1 trehalase (SfTre2) (EC 3.2.1.28) (see protein)
    34% identity, 88% coverage of query (254 bits)

7eawA / Q9SU50 Trehalase of arabidopsis thaliana acid mutant -d380a trehalose complex
    37% identity, 71% coverage of query (253 bits)

A0A0F6PAZ3 alpha,alpha-trehalase (EC 3.2.1.28) from Helicoverpa armigera (see paper)
    33% identity, 90% coverage of query (249 bits)

C0LZJ6 alpha,alpha-trehalase (EC 3.2.1.28) from Nilaparvata lugens (see paper)
ACN85420.1 trehalase (Tre-1) (soluble) (EC 3.2.1.28) (see protein)
    33% identity, 84% coverage of query (249 bits)

D2KHI9 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera litura (see paper)
    33% identity, 88% coverage of query (249 bits)

J7EJ73 alpha,alpha-trehalase (EC 3.2.1.28) from Chironomus riparius (see paper)
ADT91708.1 trehalase (Tre-1) (EC 3.2.1.28) (see protein)
    34% identity, 85% coverage of query (245 bits)

AGK89798.1 soluble trehalase (ALTre-1) (EC 3.2.1.28) (see protein)
    31% identity, 86% coverage of query (234 bits)

B0CV22 alpha,alpha-trehalase (EC 3.2.1.28) from Laccaria bicolor (see paper)
    30% identity, 83% coverage of query (229 bits)

Build an alignment

Build an alignment for BWI76_RS17700 and 44 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AAW44482.1 neutral trehalase 2 (NTH2;CNG00690) (EC 3.2.1.28) (see protein)
    29% identity, 71% coverage of query (176 bits)

TREA_BEAB2 / J5K1E2 Cytosolic neutral trehalase; Alpha,alpha-trehalase; Alpha-trehalose glucohydrolase; EC 3.2.1.28 from Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae) (see paper)
A1YQE2 alpha,alpha-trehalase (EC 3.2.1.28) from Beauveria bassiana (see paper)
ABM16911.1 neutral trehalase (Nth1;BbNTH1) (EC 3.2.1.28) (see protein)
    29% identity, 70% coverage of query (156 bits)

AAB88889.1 trehalase (EC 3.2.1.28) (see protein)
    29% identity, 71% coverage of query (147 bits)

TREB_PYRO7 / O42622 Cytosolic neutral trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Magnaporthe oryzae) (see paper)
AAN46743.1 neutral trehalase (NTH1) (EC 3.2.1.28) (see protein)
EAA53721.1 neutral trehalase (NTH1;MG09471.4) (EC 3.2.1.28) (see protein)
PTH9 neutral trehalase from Magnaporthe grisea 70-15 (see paper)
    29% identity, 71% coverage of query (145 bits)

DAA05786.1 neutral trehalase (Nth1;CNAG_03785) (EC 3.2.1.28) (see protein)
    29% identity, 79% coverage of query (144 bits)

AAW41560.1 neutral trehalase 1 (NTH1;CNB02790) (EC 3.2.1.28) (see protein)
    28% identity, 79% coverage of query (143 bits)

CAC17620.1 neutral trehalase (Nthi;Ntl1) (EC 3.2.1.28) (see protein)
AAT68667.1 neutral trehalase (NTL) (EC 3.2.1.28) (see protein)
    27% identity, 71% coverage of query (139 bits)

Q6Q5X7 alpha,alpha-trehalase (EC 3.2.1.28) from Metarhizium acridum (see paper)
AAS67888.1 neutral trehalase (Ntl) (EC 3.2.1.28) (see protein)
    27% identity, 71% coverage of query (138 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory