Searching for up to 100 curated homologs for BWI76_RS17890 FitnessBrowser__Koxy:BWI76_RS17890 (322 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ManX / b1817 mannose-specific PTS enzyme IIAB component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
manX / P69797 mannose-specific PTS enzyme IIAB component from Escherichia coli (strain K12) (see 9 papers)
PTNAB_ECOLI / P69797 PTS system mannose-specific EIIAB component; EIIAB-Man; EIII-Man; EC 2.7.1.191 from Escherichia coli (strain K12) (see 10 papers)
TC 4.A.6.1.1 / P69797 PTNA aka MANX aka PTSL aka GPTB aka B1817, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose from Escherichia coli (see 10 papers)
manX / RF|NP_416331.1 PTS system mannose-specific EIIAB component; EC 2.7.1.-; EC 2.7.1.69 from Escherichia coli K12 (see 10 papers)
    94% identity, 100% coverage of query (588 bits)

Q9S4L5 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Streptococcus salivarius (see paper)
    40% identity, 99% coverage of query (251 bits)

TC 4.A.6.1.7 / Q5M5W6 ManL, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
    39% identity, 99% coverage of query (243 bits)

TC 4.A.6.1.15 / E1UCI0 PTS system, mannose-specific, IIAB component, component of The primary glucose /mannose uptake transporter, ManLMN from Listeria monocytogenes serotype 4a (strain L99)
    41% identity, 99% coverage of query (240 bits)

TC 4.A.6.1.10 / Q04GK1 Phosphotransferase system, mannose/fructose-specific component IIA, component of The hexose (glucose and fructose demonstrated) PTS uptake system from Oenococcus oeni (strain BAA-331 / PSU-1) (see paper)
    37% identity, 99% coverage of query (237 bits)

TC 4.A.6.1.6 / Q2QKM4 ManL aka EIIAB, component of Glucose porter, ManLMN from Lactobacillus casei (see paper)
    40% identity, 99% coverage of query (225 bits)

TC 4.A.6.1.11 / D2BKY7 Mannose-specificPTS system, IIAB component, component of Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa) and lactococcin A (class IIc) (Kjos et al., 2011). Transports and phosphorylates Glucose, Mannose and Glucosamine from Lactococcus lactis subsp. lactis (strain KF147) (see 2 papers)
    38% identity, 99% coverage of query (220 bits)

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Build an alignment for BWI76_RS17890 and 7 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 4.A.6.1.13 / B3WB09 Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIAB, probable mannose specific, component of Fucosyl-α-1,3-N-acetylglucosamine PTS uptake porter, AlfEFG (next to an operon encoding a fucosidase (AlfB) and a transcriptional regulator of the GntR family, AlfR) from Lactobacillus casei (strain BL23)
    29% identity, 97% coverage of query (112 bits)

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