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Searching for up to 100 curated homologs for BWI76_RS19495 FitnessBrowser__Koxy:BWI76_RS19495 (315 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YehX / b2129 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yehX / P33360 glycine betaine ABC transporter ATP binding subunit YehX from Escherichia coli (strain K12) (see 3 papers)
YEHX_ECOLI / P33360 Glycine betaine uptake system ATP-binding protein YehX; EC 7.4.2.- from Escherichia coli (strain K12) (see 2 papers)
    79% identity, 97% coverage of query (484 bits)

OPUCA_BACSU / O34992 Glycine betaine/carnitine/choline transport ATP-binding protein OpuCA from Bacillus subtilis (strain 168) (see 4 papers)
TC 3.A.1.12.4 / O34992 OPCA aka OpuCA, component of Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate from Bacillus subtilis (see 2 papers)
    48% identity, 93% coverage of query (274 bits)

OPUBA_BACSU / Q45460 Choline transport ATP-binding protein OpuBA from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.12.3 / Q45460 OPBA aka OpuBA aka PROV, component of Choline porter from Bacillus subtilis (see 3 papers)
    46% identity, 93% coverage of query (269 bits)

OPUCA_LISM4 / G2JZ44 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCA_LISMN / Q9KHT9 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes (see paper)
    51% identity, 76% coverage of query (263 bits)

OSMV_SALTY / Q8ZPK4 Osmoprotectant import ATP-binding protein OsmV; EC 7.6.2.- from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK4 ABC-type proline/glycine betaine transport system, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    42% identity, 98% coverage of query (245 bits)

TC 3.A.1.12.8 / Q93A35 BilEA aka OpuBA protein, component of A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) from Listeria monocytogenes (see 2 papers)
    42% identity, 98% coverage of query (244 bits)

TC 3.A.1.12.11 / Q8Q041 Glycine betaine transporter, ATP-binding protein, component of The glycine betaine uptake porter, GbpABCD from Methanosarcina mazei (see paper)
    42% identity, 99% coverage of query (234 bits)

Q87WH5 ABC-type quaternary amine transporter (EC 7.6.2.9) from Pseudomonas syringae (see paper)
TC 3.A.1.12.10 / Q87WH5 OpuCA aka PSPTO4575, component of The OpuC transporter selective for glycine betaine > choline, acetylcholine, carnitine and proline betaine (contains tandem cystathionine-β-synthase (CBS) domains in the ABC component of OpuC that are required for osmoregulatory function (Chen and Beattie, 2007)) from Pseudomonas syringae pv. tomato (see paper)
    42% identity, 98% coverage of query (229 bits)

EGTUA_STRP2 / A0A0H2ZLL3 Probable ergothioneine transport ATP-binding protein EgtUA; EC 7.6.2.- from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
    44% identity, 76% coverage of query (210 bits)

OPUAA_BACSU / P46920 Glycine betaine transport ATP-binding protein OpuAA; Quaternary-amine-transporting ATPase; EC 7.6.2.9 from Bacillus subtilis (strain 168) (see 2 papers)
P46920 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.2 / P46920 OPAA aka OpuAA, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 4 papers)
    38% identity, 94% coverage of query (195 bits)

GBUA_LISM4 / Q9RR46 Glycine betaine/carnitine transport ATP-binding protein GbuA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
    42% identity, 73% coverage of query (192 bits)

TMOW_PELUB / Q4FL37 Trimethylamine N-oxide transport system ATP-binding protein TmoW; TMAO transport system ATP-binding protein TmoW; EC 7.6.2.9 from Pelagibacter ubique (strain HTCC1062) (see paper)
    36% identity, 94% coverage of query (187 bits)

TMOW_RUEPO / Q5LT65 Trimethylamine N-oxide transport system ATP-binding protein TmoW; TMAO transport system ATP-binding protein TmoW; EC 7.6.2.9 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
    39% identity, 90% coverage of query (187 bits)

A0A142UTH4 ABC-type polyamine transporter (subunit 4/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    42% identity, 81% coverage of query (185 bits)

A0A077T7Z1 ABC-type quaternary amine transporter (subunit 1/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    37% identity, 91% coverage of query (184 bits)

Q8YM92 ABC-type polyamine transporter (subunit 3/3) (EC 7.6.2.11) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
    41% identity, 76% coverage of query (181 bits)

TC 3.A.1.11.7 / Q97Q42 Spermidine/putrescine import ATP-binding protein PotA, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    41% identity, 76% coverage of query (180 bits)

TC 3.A.1.6.3 / P0A4W2 Sulfate/thiosulfate import ATP-binding protein CysA aka RV2397C aka MT2468 aka MTCY253.24, component of Sulfate porter from Mycobacterium tuberculosis (see 3 papers)
    43% identity, 70% coverage of query (176 bits)

AO356_09610 ABC transporter for L-Histidine, ATPase component from Pseudomonas fluorescens FW300-N2C3
    41% identity, 70% coverage of query (175 bits)

TC 3.A.1.11.6 / Q1M7Q1 Putative ABC transporter component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    40% identity, 76% coverage of query (174 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    40% identity, 75% coverage of query (171 bits)

TC 3.A.1.1.49 / O30494 MtlK, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
    38% identity, 76% coverage of query (171 bits)

mtlK / Q4KC54 polyol ABC-type transporterATP-binding component MtlK from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    38% identity, 76% coverage of query (171 bits)

TC 3.A.1.12.6 / Q9KKE1 HutV aka HISV aka R02702 aka SMC00670, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
    40% identity, 75% coverage of query (170 bits)

sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
    40% identity, 79% coverage of query (170 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    40% identity, 77% coverage of query (166 bits)

8hprD Lpqy-sugabc in state 4
    39% identity, 77% coverage of query (166 bits)

8hprC Lpqy-sugabc in state 4
    39% identity, 77% coverage of query (165 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    39% identity, 80% coverage of query (163 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    38% identity, 76% coverage of query (163 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    38% identity, 76% coverage of query (163 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    38% identity, 76% coverage of query (163 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    38% identity, 76% coverage of query (163 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    38% identity, 76% coverage of query (163 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    38% identity, 76% coverage of query (162 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    38% identity, 76% coverage of query (162 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    38% identity, 76% coverage of query (162 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    41% identity, 72% coverage of query (160 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    37% identity, 75% coverage of query (159 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    37% identity, 75% coverage of query (159 bits)

2olkA Abc protein artp in complex with adp-beta-s
    37% identity, 75% coverage of query (159 bits)

2oljA Abc protein artp in complex with adp/mg2+
    37% identity, 75% coverage of query (159 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    38% identity, 75% coverage of query (159 bits)

1g291 / Q9YGA6 Malk (see paper)
    40% identity, 73% coverage of query (157 bits)

2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    37% identity, 71% coverage of query (147 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    36% identity, 75% coverage of query (146 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    36% identity, 75% coverage of query (145 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    36% identity, 75% coverage of query (145 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    36% identity, 75% coverage of query (144 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    36% identity, 75% coverage of query (144 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    38% identity, 78% coverage of query (140 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    32% identity, 75% coverage of query (125 bits)

HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
    36% identity, 74% coverage of query (124 bits)

1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
    36% identity, 74% coverage of query (124 bits)

ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    33% identity, 77% coverage of query (120 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    33% identity, 71% coverage of query (119 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    33% identity, 71% coverage of query (119 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    31% identity, 70% coverage of query (118 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    31% identity, 70% coverage of query (118 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    31% identity, 70% coverage of query (118 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    33% identity, 71% coverage of query (118 bits)

ABCA4_BOVIN / F1MWM0 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Retinal-specific ATP-binding cassette transporter; EC 7.6.2.1 from Bos taurus (Bovine) (see 11 papers)
    33% identity, 71% coverage of query (116 bits)

7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
    33% identity, 72% coverage of query (113 bits)

4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
    33% identity, 72% coverage of query (112 bits)

4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
    31% identity, 70% coverage of query (112 bits)

ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
    31% identity, 73% coverage of query (112 bits)

ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
    32% identity, 73% coverage of query (111 bits)

P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
    32% identity, 71% coverage of query (111 bits)

MDR3_HUMAN / P21439 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; EC 7.6.2.1 from Homo sapiens (Human) (see 28 papers)
TC 3.A.1.201.3 / P21439 Short chain fatty acid phosphatidylcholine translocase (phospholipid flippase), MDR3; AbcB4; Pgy3 from Homo sapiens (Human) (see 15 papers)
    34% identity, 70% coverage of query (111 bits)

2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    30% identity, 76% coverage of query (110 bits)

6s7pA Nucleotide bound abcb4
    34% identity, 70% coverage of query (110 bits)

7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
    34% identity, 70% coverage of query (110 bits)

7lkpA Structure of atp-free human abca4
    30% identity, 78% coverage of query (109 bits)

8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
    32% identity, 70% coverage of query (108 bits)

5d3mB Folate ecf transporter: amppnp bound state
    32% identity, 70% coverage of query (108 bits)

Build an alignment

Build an alignment for BWI76_RS19495 and 75 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

7roqA / O95477 Alternative structure of human abca1
    28% identity, 83% coverage of query (108 bits)

4q9iA P-glycoprotein cocrystallised with qz-ala
    33% identity, 75% coverage of query (108 bits)

IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
    33% identity, 70% coverage of query (108 bits)

6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
    33% identity, 71% coverage of query (108 bits)

3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    33% identity, 71% coverage of query (108 bits)

3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    33% identity, 71% coverage of query (108 bits)

7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
    33% identity, 71% coverage of query (108 bits)

4xwkA P-glycoprotein co-crystallized with bde-100
    33% identity, 71% coverage of query (107 bits)

6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
    33% identity, 71% coverage of query (107 bits)

8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    32% identity, 70% coverage of query (107 bits)

8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    32% identity, 71% coverage of query (107 bits)

6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
    33% identity, 71% coverage of query (107 bits)

5koyA Mouse pgp 34 linker deleted bound with atp
    33% identity, 71% coverage of query (106 bits)

5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
    32% identity, 71% coverage of query (106 bits)

ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
    29% identity, 73% coverage of query (105 bits)

4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
    33% identity, 71% coverage of query (105 bits)

MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
    32% identity, 73% coverage of query (105 bits)

7ph2A Nanodisc reconstituted msba in complex with nanobodies, spin-labeled at position a60c
    32% identity, 73% coverage of query (104 bits)

8dmmA Structure of the vanadate-trapped msba bound to kdl
    32% identity, 73% coverage of query (104 bits)

7wixA Cryo-em structure of mycobacterium tuberculosis irtab in complex with adp
    33% identity, 70% coverage of query (104 bits)

7wivA / P9WQJ9 Cryo-em structure of mycobacterium tuberculosis irtab in complex with an amp-pnp
    33% identity, 70% coverage of query (104 bits)

7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
    32% identity, 73% coverage of query (104 bits)

6bppA E. Coli msba in complex with lps and inhibitor g092
    32% identity, 73% coverage of query (104 bits)

6bplA E. Coli msba in complex with lps and inhibitor g907
    32% identity, 73% coverage of query (104 bits)

7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
    33% identity, 73% coverage of query (104 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory