Sites on a Tree

 

Searching for up to 100 curated homologs for BWI76_RS20035 FitnessBrowser__Koxy:BWI76_RS20035 (326 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.80.1.1 / Q9FA46 TctC aka STM2786, component of The tricarboxylate transporter, TctABC from Salmonella enterica (see paper)
    84% identity, 100% coverage of query (571 bits)

HP15_2661 Citrate uptake transporter, substrate-binding component TctC from Marinobacter adhaerens HP15
    35% identity, 91% coverage of query (189 bits)

Build an alignment

Build an alignment for BWI76_RS20035 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TC 2.A.80.1.4 / S5XTE7 Citrate uptake transporter, substrate binding protein, component of Pmf-dependent citrate uptake porter, TctABC from Corynebacterium glutamicum MB001
    29% identity, 91% coverage of query (117 bits)

Dshi_3123 Tricarboxylate transport protein TctC from Dinoroseobacter shibae DFL-12
    25% identity, 75% coverage of query (94.7 bits)

7ndsA / A0A5N7XFM8 Crystal structure of tphc in a closed conformation (see paper)
    22% identity, 78% coverage of query (54.3 bits)

7ndrD Crystal structure of tphc in an open conformation
    22% identity, 78% coverage of query (54.3 bits)

tphCII / BAE47084.1 periplasmic terephthalate binding receptor from Comamonas sp. E6 (see paper)
    22% identity, 78% coverage of query (53.9 bits)

TC 2.A.80.1.2 / Q5D0X7 Terephthalate permease, component of Terephthalate (TPA) aromatic acid uptake transport system, TpiBA/TphC from Comamonas testosteroni
    21% identity, 89% coverage of query (53.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory