Searching for up to 100 curated homologs for BWI76_RS20790 FitnessBrowser__Koxy:BWI76_RS20790 (467 a.a.)
Found high-coverage hits (≥70%) to 80 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
eutE / P41793 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
EUTE_SALTY / P41793 Acetaldehyde dehydrogenase (acetylating) EutE; Ethanolamine utilization protein EutE; EC 1.2.1.10 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 10 papers)
96% identity, 100% coverage of query (889 bits)
YffX / b2455 acetaldehyde dehydrogenase (acetylating) EutE (EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
eutE / P77445 acetaldehyde dehydrogenase (acetylating) EutE (EC 1.2.1.10) from Escherichia coli (strain K12) (see 5 papers)
EUTE_ECOLI / P77445 Acetaldehyde dehydrogenase (acetylating) EutE; Ethanolamine utilization protein EutE; EC 1.2.1.10 from Escherichia coli (strain K12) (see paper)
94% identity, 100% coverage of query (841 bits)
adhE / E5Y379 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Bilophila wadsworthia (strain 3_1_6) (see paper)
ADHE_BILW3 / E5Y379 Acetaldehyde dehydrogenase (acetylating); CoA-acylating acetaldehyde dehydrogenase; EC 1.2.1.10 from Bilophila wadsworthia (strain 3_1_6) (see paper)
60% identity, 100% coverage of query (543 bits)
B0K315 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter sp. (see paper)
52% identity, 94% coverage of query (448 bits)
pduP / Q9XDN1 CoA-dependent propanal dehydrogenase (EC 1.2.1.87) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 8 papers)
PDUP_SALTY / Q9XDN1 Propanal dehydrogenase (CoA-propanoylating); Coenzyme-A-acylating propionaldehyde dehydrogenase; Propanediol utilization protein PduP; EC 1.2.1.87 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 9 papers)
46% identity, 100% coverage of query (398 bits)
PDUP_CITFR / B1VB75 Propanal dehydrogenase (CoA-propanoylating); Coenzyme-A-acylating propionaldehyde dehydrogenase; Propanediol utilization protein PduP; EC 1.2.1.87 from Citrobacter freundii (see 2 papers)
45% identity, 100% coverage of query (386 bits)
A9KN57 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Lachnoclostridium phytofermentans (see paper)
43% identity, 100% coverage of query (379 bits)
4c3sA / A9KN57 Structure of a propionaldehyde dehydrogenase from the clostridium phytofermentans fucose utilisation bacterial microcompartment (see paper)
44% identity, 94% coverage of query (372 bits)
5jfmB / Q21A49 Crystal structure of rhodopseudomonas palustris propionaldehyde dehydrogenase with bound propionyl-coa (see paper)
46% identity, 93% coverage of query (370 bits)
5jfmA Crystal structure of rhodopseudomonas palustris propionaldehyde dehydrogenase with bound propionyl-coa
46% identity, 93% coverage of query (370 bits)
5jflA Crystal structure of rhodopseudomonas palustris propionaldehyde dehydrogenase with bound NAD+
46% identity, 93% coverage of query (370 bits)
6gvsA Engineered glycolyl-coa reductase comprising 8 mutations with bound NADP+
45% identity, 93% coverage of query (361 bits)
5dbvA Structure of a c269a mutant of propionaldehyde dehydrogenase from the clostridium phytofermentans fucose utilisation bacterial microcompartment
43% identity, 94% coverage of query (357 bits)
Build an alignment for BWI76_RS20790 and 13 homologs with ≥ 30% identity
Or download the sequences
B0K4A2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter sp. X514 (see 2 papers)
29% identity, 92% coverage of query (181 bits)
Q0PH30 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter ethanolicus (see paper)
29% identity, 97% coverage of query (180 bits)
B0KBJ9 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter pseudethanolicus (see paper)
29% identity, 92% coverage of query (179 bits)
A0A1D3TRQ6 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Anaerobium acetethylicum (see paper)
33% identity, 78% coverage of query (177 bits)
A0A0H3W5V0 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Thermoanaerobacterium saccharolyticum (see paper)
29% identity, 93% coverage of query (177 bits)
A0A0H3W5K4 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum (see paper)
I3VSF1 alcohol dehydrogenase (EC 1.1.1.1); L-lactate dehydrogenase (EC 1.1.1.27); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum (see paper)
29% identity, 93% coverage of query (177 bits)
AdhE / b1241 fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655 (see 62 papers)
adhE / P0A9Q7 fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli (strain K12) (see 64 papers)
ADHE_ECOLI / P0A9Q7 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) (see 13 papers)
ADHE_ECO57 / P0A9Q8 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli O157:H7 (see 2 papers)
P0A9Q7 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Escherichia coli (see paper)
adhE / MB|P0A9Q7 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Escherichia coli K12 (see 12 papers)
36% identity, 72% coverage of query (171 bits)
7bvpA / P0A9Q7 Adhe spirosome in extended conformation (see paper)
36% identity, 72% coverage of query (171 bits)
6tqmA Escherichia coli adhe structure in its compact conformation
36% identity, 72% coverage of query (171 bits)
adhE2 / Q9ANR5 aldehyde dehydrogenase/alcohol dehydrogenase (EC 1.2.1.57) from Clostridium acetobutylicum (see 4 papers)
32% identity, 79% coverage of query (170 bits)
5j7iB Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp (see paper)
31% identity, 84% coverage of query (166 bits)
5j7iC Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp
31% identity, 84% coverage of query (166 bits)
adhE / P33744 alcohol/aldehyde dehydrogenase (EC 1.1.1.1; EC 1.2.1.10; EC 1.2.1.57) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see 4 papers)
ADHE_CLOAB / P33744 Aldehyde-alcohol dehydrogenase; AAD; EC 1.1.1.1; EC 1.2.1.3 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see paper)
aad / GB|AAD04638.1 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Clostridium acetobutylicum ATCC 824 (see paper)
aad / AAD04638.1 aldehyde-alcohol dehydrogenase from Clostridium acetobutylicum (see 2 papers)
32% identity, 81% coverage of query (165 bits)
ADH1 / A8JI07 alcohol dehydrogenase / acetaldehyde dehydrogenase (EC 1.2.1.10; EC 1.1.1.1) from Chlamydomonas reinhardtii (see 2 papers)
31% identity, 79% coverage of query (155 bits)
ADHE_STRPN / A0A0H2URT2 Aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.3 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see paper)
31% identity, 76% coverage of query (154 bits)
ADHE_STRP2 / A0A0H2ZM56 Aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.3 from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
31% identity, 76% coverage of query (154 bits)
A0A0H3W5U9 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Acetivibrio thermocellus (see 3 papers)
A3DCI2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Acetivibrio thermocellus (see 4 papers)
30% identity, 76% coverage of query (154 bits)
8cejA / P38947 Succinyl-coa reductase from clostridium kluyveri (sucd) with mesaconyl-c1-coa (see paper)
29% identity, 86% coverage of query (153 bits)
sucD / P38947 succinate semialdehyde dehydrogenase subunit (EC 1.2.1.76) from Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) (see 3 papers)
sucD / GB|AAA92347.1 succinate-semialdehyde dehydrogenase [NAD(P)+]; EC 1.2.1.16 from Clostridium kluyveri DSM 555 (see paper)
29% identity, 86% coverage of query (153 bits)
8cekA Succinyl-coa reductase from clostridium kluyveri (sucd) with NADPH
29% identity, 86% coverage of query (153 bits)
8cejC Succinyl-coa reductase from clostridium kluyveri (sucd) with mesaconyl-c1-coa
29% identity, 86% coverage of query (153 bits)
Q1RS84 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Chlamydomonas reinhardtii (see paper)
31% identity, 79% coverage of query (149 bits)
ADH2_ENTH1 / Q24803 Aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM) (see 2 papers)
28% identity, 92% coverage of query (137 bits)
adh2 / GB|AAA81906.1 aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica (see paper)
AAA81906.1 alcohol dehydrogenase 2 from Entamoeba histolytica (see paper)
29% identity, 82% coverage of query (136 bits)
SQWD_ACHSX / A0A3A6N9T6 Sulfoacetaldehyde dehydrogenase; CoA-acylating sulfoacetaldehyde dehydrogenase; NAD(+)-dependent acylating sulfoacetaldehyde dehydrogenase; EC 1.2.1.- from Acholeplasma sp. (see paper)
28% identity, 84% coverage of query (132 bits)
Q70YJ9 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Polytomella sp. Pringsheim 198.80 (see paper)
30% identity, 76% coverage of query (130 bits)
SauS / Q0K845 sulfoacetaldehyde dehydrogenase (acylating) subunit (EC 1.2.1.81) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
SAUS_CUPNH / Q0K845 Sulfoacetaldehyde dehydrogenase (acylating); EC 1.2.1.81 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
Q0K845 sulfoacetaldehyde dehydrogenase (acylating) (EC 1.2.1.81) from Cupriavidus necator (see paper)
31% identity, 76% coverage of query (128 bits)
Noca_4822 / A1SC71 2-hydroxyethyl-CoM 2-dehydrogenase from Nocardioides sp. (strain ATCC BAA-499 / JS614) (see 2 papers)
29% identity, 82% coverage of query (114 bits)
SAUS_BILW3 / E5Y8P9 Sulfoacetaldehyde dehydrogenase (acylating); NADPH-dependent acylating sulfoacetaldehyde dehydrogenase; Sulfoacetyl-CoA reductase; EC 1.2.1.81 from Bilophila wadsworthia (strain 3_1_6) (see paper)
28% identity, 73% coverage of query (106 bits)
AldH / b1300 γ-glutamyl-γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19; EC 1.2.1.24; EC 1.2.1.99) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
puuC / P23883 γ-glutamyl-γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19; EC 1.2.1.24; EC 1.2.1.99) from Escherichia coli (strain K12) (see 6 papers)
PUUC_ECOLI / P23883 NADP/NAD-dependent aldehyde dehydrogenase PuuC; ALDH; 3-hydroxypropionaldehyde dehydrogenase; Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase; EC 1.2.1.5 from Escherichia coli (strain K12) (see 2 papers)
P23883 4-(gamma-glutamylamino)butanal dehydrogenase (EC 1.2.1.99) from Escherichia coli (see 3 papers)
puuC / BAD88708.1 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase from Escherichia coli K-12 (see paper)
25% identity, 82% coverage of query (79.0 bits)
ASC1_DIDFA / A0A5C1REZ4 Aldehyde dehydrogenase; Ascochitine biosynthesis cluster protein 1; EC 1.2.1.3 from Didymella fabae (Leaf and pod spot disease fungus) (Ascochyta fabae) (see paper)
25% identity, 82% coverage of query (77.0 bits)
Sama_3009 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Shewanella amazonensis SB2B
27% identity, 70% coverage of query (77.0 bits)
SO0619 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) from Shewanella oneidensis MR-1
25% identity, 71% coverage of query (72.4 bits)
3rhdA / Q58806 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn from methanocaldococcus jannaschii dsm 2661 complexed with NADP
24% identity, 79% coverage of query (66.6 bits)
AL3B3_MOUSE / J3QMK6 Aldehyde dehydrogenase family 3 member B3; EC 1.2.1.3 from Mus musculus (Mouse) (see paper)
J3QMK6 long-chain-aldehyde dehydrogenase (EC 1.2.1.48) from Mus musculus (see paper)
24% identity, 73% coverage of query (62.4 bits)
2j5nA 1-pyrroline-5-carboxylate dehydrogenase from thermus thermophirus with bound inhibitor glycine and NAD.
24% identity, 72% coverage of query (59.7 bits)
2ej6A Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound d-proline
24% identity, 72% coverage of query (59.7 bits)
2eitA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-alanine and NAD
24% identity, 72% coverage of query (59.7 bits)
2eiiA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-valine and NAD.
24% identity, 72% coverage of query (59.7 bits)
2ehuA Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound NAD and inhibitor l-serine
24% identity, 72% coverage of query (59.7 bits)
2ehqA Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound NADP
24% identity, 72% coverage of query (59.7 bits)
2bhqA Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound product glutamate.
24% identity, 72% coverage of query (59.7 bits)
2bhpA / Q5SI02 Crystal analysis of 1-pyrroline-5-carboxylate dehydrogenase from thermus with bound NAD. (see paper)
24% identity, 72% coverage of query (59.7 bits)
2eiwA Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from thermus thermophilus with bound l-proline
24% identity, 72% coverage of query (59.3 bits)
AL3B2_MOUSE / E9Q3E1 Aldehyde dehydrogenase family 3 member B2; Aldehyde dehydrogenase 8; EC 1.2.1.3 from Mus musculus (Mouse) (see paper)
E9Q3E1 long-chain-aldehyde dehydrogenase (EC 1.2.1.48) from Mus musculus (see paper)
25% identity, 73% coverage of query (58.5 bits)
5u0mA Fatty aldehyde dehydrogenase from marinobacter aquaeolei vt8 and cofactor complex
25% identity, 83% coverage of query (57.8 bits)
5u0lA / A1U5W8 X-ray crystal structure of fatty aldehyde dehydrogenase enzymes from marinobacter aquaeolei vt8 complexed with a substrate (see paper)
25% identity, 83% coverage of query (57.8 bits)
4iymC / Q92RW4 Crystal structure of putative methylmalonate-semialdehyde dehydrogenase from sinorhizobium meliloti 1021 complexed with NAD, target 011934
23% identity, 71% coverage of query (57.0 bits)
AL3B1_HUMAN / P43353 Aldehyde dehydrogenase family 3 member B1; Aldehyde dehydrogenase 7; EC 1.2.1.28; EC 1.2.1.5; EC 1.2.1.7 from Homo sapiens (Human) (see 2 papers)
P43353 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see paper)
24% identity, 73% coverage of query (56.2 bits)
4cazA / Q9HTJ1 Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
24% identity, 81% coverage of query (55.5 bits)
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct.
24% identity, 81% coverage of query (55.5 bits)
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa
24% identity, 81% coverage of query (55.5 bits)
BETB_PSEAE / Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HTJ1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Pseudomonas aeruginosa (see 5 papers)
24% identity, 81% coverage of query (55.1 bits)
3hazA / Q89E26 Crystal structure of bifunctional proline utilization a (puta) protein (see paper)
25% identity, 82% coverage of query (54.7 bits)
3u4jA / Q930S8 Crystal structure of NAD-dependent aldehyde dehydrogenase from sinorhizobium meliloti
25% identity, 70% coverage of query (52.8 bits)
6bsnA Structure of proline utilization a (puta) with proline bound in remote sites
24% identity, 82% coverage of query (50.8 bits)
AL3A1_HUMAN / P30838 Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1; EC 1.2.1.5 from Homo sapiens (Human) (see 2 papers)
P30838 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 8 papers)
23% identity, 73% coverage of query (50.4 bits)
6j76A Structure of 3,6-anhydro-l-galactose dehydrogenase in complex with nap (see paper)
24% identity, 83% coverage of query (50.1 bits)
8bb8A Crystal structure of human aldehyde dehydrogenase aldh3a1 in complex with octanal
23% identity, 73% coverage of query (50.1 bits)
4l1oB / P30838 Crystal structure of human aldh3a1 with inhibitor 1-{[4-(1,3- benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1h-indole-2,3-dione
23% identity, 73% coverage of query (49.3 bits)
3szbA Crystal structure of human aldh3a1 modified with the beta-elimination product of aldi-1; 1-phenyl- 2-propen-1-one
23% identity, 73% coverage of query (48.9 bits)
4l2oA Crystal structure of human aldh3a1 with its selective inhibitor 1-(4- fluorophenyl)sulfonyl-2-methylbenzimidazole
23% identity, 73% coverage of query (48.9 bits)
4h80A Crystal structure of human aldh3a1 with its isozyme selective inhibitor - n-[4-(4-methylsulfonyl-2-nitroanilino)phenyl]acetamide
23% identity, 73% coverage of query (48.9 bits)
4zz7A / G5CZI2 Crystal structure of methylmalonate-semialdehyde dehydrogenase (dddc) from oceanimonas doudoroffii (see paper)
23% identity, 75% coverage of query (47.8 bits)
2d4eC / Q5SJP9 Crystal structure of the hpcc from thermus thermophilus hb8
23% identity, 82% coverage of query (46.6 bits)
4itbA / B1XMM6 Structure of bacterial enzyme in complex with cofactor and substrate (see paper)
23% identity, 91% coverage of query (45.1 bits)
VDH_CORGL / Q8NMB0 Vanillin dehydrogenase; Aromatic aldehyde dehydrogenase; EC 1.2.1.67; EC 1.2.1.64; EC 1.2.1.96 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NMB0 vanillin dehydrogenase (EC 1.2.1.67) from Corynebacterium glutamicum (see paper)
26% identity, 87% coverage of query (43.5 bits)
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