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Searching for up to 100 curated homologs for BWI76_RS22075 FitnessBrowser__Koxy:BWI76_RS22075 (331 a.a.)

Found high-coverage hits (≥70%) to 6 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

OsrA / b2679 glycine betaine ABC transporter periplasmic binding protein ProX (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
proX / P0AFM2 glycine betaine ABC transporter periplasmic binding protein ProX (EC 7.6.2.9) from Escherichia coli (strain K12) (see 2 papers)
PROX_ECOLI / P0AFM2 Glycine betaine/proline betaine-binding periplasmic protein; GBBP from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.12.1 / P0AFM2 ProX aka ProU aka B2679, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli (see 6 papers)
proX / RF|NP_417165 glycine betaine-binding periplasmic protein from Escherichia coli K12 (see 7 papers)
    86% identity, 100% coverage of query (599 bits)

1r9qA / P0AFM2 Structure analysis of prox in complex with proline betaine (see paper)
    88% identity, 94% coverage of query (572 bits)

OUSX_DICD3 / E0SCY3 Glycine betaine-binding periplasmic protein OusX from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    79% identity, 100% coverage of query (559 bits)

A0A077T7U5 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    65% identity, 98% coverage of query (452 bits)

Build an alignment

Build an alignment for BWI76_RS22075 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

TC 3.A.1.12.6 / Q9KKE3 HutX aka HISX, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    24% identity, 76% coverage of query (73.9 bits)

TC 3.A.1.12.9 / Q8U4S3 OtaC, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
    22% identity, 87% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory