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Searching for up to 100 curated homologs for BWI76_RS22400 FitnessBrowser__Koxy:BWI76_RS22400 (104 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 4.A.3.2.9 / U5MIE1 PTS lactose transporter subunit IIB, component of PTS-type lactose transporter, IIC-IIB-IIA from Klebsiella pneumoniae CG43
    55% identity, 98% coverage of query (108 bits)

TC 4.A.3.2.6 / Q9KSH5 VC_1281 aka IIB, component of Glucosamine β(1→4) glucosamine (GlcN)2 (glucosamine dimer) transporter, VC1281-1283 (IIB; IIC; IIA, respectively) from Vibrio cholerae (see paper)
    51% identity, 97% coverage of query (103 bits)

PTEB_BACSU / O05505 PTS system oligo-beta-mannoside-specific EIIB component; Glucomannan utilization protein B; Oligo-beta-mannoside-specific phosphotransferase enzyme IIB component; EC 2.7.1.205 from Bacillus subtilis (strain 168) (see paper)
    48% identity, 99% coverage of query (90.5 bits)

TC 4.A.3.2.8 / Q72XP9 PTS system, cellobiose-specific IIB component, component of N-, N'-diacetylchitobiose PTS permease, IIABCChb from Bacillus cereus (strain ATCC 10987)
    41% identity, 92% coverage of query (78.6 bits)

TC 4.A.3.2.3 / O50982 ChbB, component of N,N'-diacetylchitobiose porter, ChbABC from Borrelia burgdorferi (Lyme disease spirochete) (see paper)
    37% identity, 97% coverage of query (73.9 bits)

PTCB_LACLM / A2RIE6 PTS system galactose-specific EIIB component; Galactose-specific phosphotransferase enzyme IIB component; EC 2.7.1.204 from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    42% identity, 96% coverage of query (73.2 bits)

PTCB_LACLA / Q9CIF0 PTS system cellobiose-specific EIIB component; Cellobiose-specific phosphotransferase enzyme IIB component; EC 2.7.1.205 from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) (see 2 papers)
TC 4.A.3.2.4 / Q9CIF0 PtcB, component of The cellobiose-specific (PtcA-PtcB-CelB) porter (Kowalczyk et al., 2008 ) from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see paper)
    42% identity, 96% coverage of query (72.0 bits)

TC 4.A.3.2.2 / P46318 PTCB aka LicB aka CELA, component of Lichenan oligosaccharide (Lic) porter from Bacillus subtilis (see 4 papers)
    42% identity, 89% coverage of query (69.7 bits)

P46318 Lichenan-specific phosphotransferase enzyme IIB component; EIIB-Lic; PTS system lichenan-specific EIIB component; EC 2.7.1.- from Bacillus subtilis (strain 168)
    42% identity, 89% coverage of query (69.7 bits)

TC 4.A.3.2.5 / Q8L3C3 ChbB, component of The N,N' -diacetylchitobiose Enzyme II (Toratani et al., 2008) (>80% identical to the E. coli enzyme (4.A.3.2.1)) from Serratia marcescens (see paper)
    45% identity, 88% coverage of query (63.9 bits)

2wy2D / P69795 Nmr structure of the iiachitobiose-iibchitobiose phosphoryl transition state complex of the n,n'-diacetylchitoboise brance of the e. Coli phosphotransferase system. (see paper)
    45% identity, 88% coverage of query (63.5 bits)

ChbB / b1738 N,N'-diacetylchitobiose-specific PTS enzyme IIB component (EC 2.7.1.196) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ChbB / P69795 N,N'-diacetylchitobiose-specific PTS enzyme IIB component (EC 2.7.1.196) from Escherichia coli (strain K12) (see 2 papers)
PTQB_ECOLI / P69795 PTS system N,N'-diacetylchitobiose-specific EIIB component; EIIB-Chb; IVcel; N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component; EC 2.7.1.196 from Escherichia coli (strain K12) (see 4 papers)
P69795 protein-Npi-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase (EC 2.7.1.196) from Escherichia coli (see paper)
TC 4.A.3.2.1 / P69795 PTCB aka ChbB aka CELA aka B1738, component of N,N'-diacetylchitobiose (Chb) porter from Escherichia coli (see 12 papers)
    45% identity, 88% coverage of query (63.5 bits)

TC 4.A.3.2.7 / C4X744 Cellobiose-specific PTS family enzyme IIB component, component of N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC) from Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
    43% identity, 88% coverage of query (62.0 bits)

Build an alignment

Build an alignment for BWI76_RS22400 and 13 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PTLCB_STAAU / P11162 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Staphylococcus aureus (see 7 papers)
TC 4.A.3.1.1 / P11162 PtlB aka LACE, component of Lactose (Lac) porter, LacEF from Staphylococcus aureus (see paper)
    27% identity, 95% coverage of query (49.3 bits)

PTLCB_LACCA / P24400 PTS system lactose-specific EIICB component; EIICB-Lac; EII-Lac; EC 2.7.1.207 from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
    25% identity, 91% coverage of query (41.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory