Searching for up to 100 curated homologs for BWI76_RS22415 FitnessBrowser__Koxy:BWI76_RS22415 (304 a.a.)
Found high-coverage hits (≥70%) to 70 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Mak / b0394 fructokinase (EC 2.7.1.7; EC 2.7.1.4) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
mak / P23917 fructokinase (EC 2.7.1.7; EC 2.7.1.4) from Escherichia coli (strain K12) (see 8 papers)
MAK_ECOLI / P23917 Fructokinase; D-fructose kinase; Manno(fructo)kinase; EC 2.7.1.4 from Escherichia coli (strain K12) (see 2 papers)
47% identity, 96% coverage of query (271 bits)
Sama_1405 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
47% identity, 96% coverage of query (256 bits)
SMc03109 Mannokinase (EC 2.7.1.7) from Sinorhizobium meliloti 1021
44% identity, 96% coverage of query (255 bits)
Sama_2231 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
46% identity, 96% coverage of query (244 bits)
7p7wBBB / Q12306,R8APY9 7p7wBBB
40% identity, 96% coverage of query (196 bits)
7p9lAAA Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
40% identity, 96% coverage of query (196 bits)
7p9pAAA Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
40% identity, 96% coverage of query (196 bits)
4db3A / Q8D9M7 1.95 angstrom resolution crystal structure of n-acetyl-d-glucosamine kinase from vibrio vulnificus.
37% identity, 97% coverage of query (191 bits)
YcfX / b1119 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
nagK / P75959 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) from Escherichia coli (strain K12) (see 6 papers)
NAGK_ECOLI / P75959 N-acetyl-D-glucosamine kinase; GlcNAc kinase; EC 2.7.1.59 from Escherichia coli (strain K12) (see 2 papers)
nagK / GB|ABB62126.1 N-acetyl-D-glucosamine kinase; EC 2.7.1.59 from Escherichia coli K12 (see 5 papers)
36% identity, 97% coverage of query (182 bits)
agaK / A0KYQ6 N-acetylgalactosamine kinase from Shewanella sp. (strain ANA-3) (see paper)
AGAK_SHESA / A0KYQ6 N-acetylgalactosamine kinase AgaK; GalNAc kinase; N-acetylglucosamine kinase; GlcNAc kinase; EC 2.7.1.-; EC 2.7.1.59 from Shewanella sp. (strain ANA-3) (see paper)
39% identity, 96% coverage of query (173 bits)
NAGK_SALTY / Q8ZPZ9 N-acetyl-D-glucosamine kinase; GlcNAc kinase; EC 2.7.1.59 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
36% identity, 97% coverage of query (157 bits)
2ap1A / Q8ZPZ9 Crystal structure of the putative regulatory protein
36% identity, 97% coverage of query (157 bits)
Build an alignment for BWI76_RS22415 and 12 homologs with ≥ 30% identity
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Q8R8N4 ADP-specific glucose/glucosamine kinase (EC 2.7.1.147) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
27% identity, 96% coverage of query (122 bits)
glk / Q9X1I0 glucokinase subunit (EC 2.7.1.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
GLK_THEMA / Q9X1I0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
29% identity, 95% coverage of query (105 bits)
glcK / GI|1303865 glucokinase; EC 2.7.1.2 from Bacillus subtilis (see paper)
30% identity, 95% coverage of query (94.7 bits)
glcK / P54495 glucokinase (EC 2.7.1.1) from Bacillus subtilis (strain 168) (see paper)
GLK_BACSU / P54495 Glucokinase; Glucose kinase; EC 2.7.1.2 from Bacillus subtilis (strain 168) (see paper)
P54495 glucokinase (EC 2.7.1.2) from Bacillus subtilis (see paper)
29% identity, 95% coverage of query (93.6 bits)
O31392 glucokinase (EC 2.7.1.2) from Priestia megaterium (see paper)
glk glucokinase; EC 2.7.1.2 from Bacillus megaterium (see paper)
glk / CAA03848.1 glucose kinase from Bacillus megaterium (see paper)
30% identity, 95% coverage of query (85.5 bits)
rokA / Q5GBH5 glucokinase / N-acetylglucosamine kinase / mannokinase (EC 2.7.1.7; EC 2.7.1.1; EC 2.7.1.59) from Bacteroides fragilis (see 2 papers)
29% identity, 83% coverage of query (83.2 bits)
BGLK_KLEPN / Q93LQ8 Beta-glucoside kinase; EC 2.7.1.85 from Klebsiella pneumoniae (see paper)
28% identity, 80% coverage of query (82.4 bits)
IolR / VIMSS1300 IolR regulator of Inositol utilization (repressor) from Thermotoga maritima MSB8
27% identity, 86% coverage of query (82.4 bits)
2qm1B / Q830J4 Crystal structure of glucokinase from enterococcus faecalis
27% identity, 98% coverage of query (82.0 bits)
YjcT / b4084 D-allose kinase (EC 2.7.1.55) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
alsK / P32718 D-allose kinase (EC 2.7.1.55) from Escherichia coli (strain K12) (see 4 papers)
ALSK_ECOLI / P32718 D-allose kinase; Allokinase; EC 2.7.1.55 from Escherichia coli (strain K12) (see 2 papers)
alsK / RF|NP_418508 D-allose kinase; EC 2.7.1.55 from Escherichia coli K12 (see 6 papers)
26% identity, 95% coverage of query (81.3 bits)
NanR / VIMSS3720738 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides vulgatus ATCC 8482
24% identity, 91% coverage of query (80.9 bits)
1z05A / Q9KQJ1 Crystal structure of the rok family transcriptional regulator, homolog of e.Coli mlc protein.
23% identity, 95% coverage of query (80.5 bits)
Q8RDE9 glucokinase (EC 2.7.1.2) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
26% identity, 95% coverage of query (80.5 bits)
CA265_RS11300 N-acetylglucosamine kinase (EC 2.7.1.59) from Pedobacter sp. GW460-11-11-14-LB5
25% identity, 95% coverage of query (78.2 bits)
GLK_STRCO / P0A4E1 Glucokinase; Glucose kinase; ORF 3; EC 2.7.1.2 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
P0A4E1 glucokinase (EC 2.7.1.2) from Streptomyces coelicolor (see paper)
glkA glucokinase; EC 2.7.1.2 from Streptomyces coelicolor (see 2 papers)
27% identity, 96% coverage of query (77.0 bits)
XylR / VIMSS6926953 XylR regulator of Xylose utilization, effector Xylose (repressor) from Paenibacillus sp. JDR-2
25% identity, 96% coverage of query (77.0 bits)
2yi1A Crystal structure of n-acetylmannosamine kinase in complex with n- acetyl mannosamine 6-phosphate and adp.
27% identity, 82% coverage of query (77.0 bits)
2yhyA Structure of n-acetylmannosamine kinase in complex with n- acetylmannosamine and adp
27% identity, 82% coverage of query (77.0 bits)
GLCNE_HUMAN / Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Homo sapiens (Human) (see 24 papers)
Q9Y223 N-acylmannosamine kinase (EC 2.7.1.60); UDP-N-acetylglucosamine 2-epimerase (hydrolysing) (EC 3.2.1.183); UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) (EC 5.1.3.14) from Homo sapiens (see 18 papers)
28% identity, 82% coverage of query (76.3 bits)
Gne / O35826 bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase subunit (EC 2.7.1.60; EC 3.2.1.183) from Rattus norvegicus (see paper)
GLCNE_RAT / O35826 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Rattus norvegicus (Rat) (see 5 papers)
28% identity, 82% coverage of query (76.3 bits)
GLCNE_MOUSE / Q91WG8 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Mus musculus (Mouse) (see 3 papers)
Q91WG8 UDP-N-acetylglucosamine 2-epimerase (hydrolysing) (EC 3.2.1.183) from Mus musculus (see paper)
28% identity, 82% coverage of query (76.3 bits)
GLCNE_CRIGR / Q7TQ49 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; EC 3.2.1.183; EC 2.7.1.60 from Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (see paper)
27% identity, 82% coverage of query (75.9 bits)
NanR / VIMSS6110394 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides plebeius DSM 17135
22% identity, 95% coverage of query (75.5 bits)
glkA / CAA62003.1 glucokinase from Renibacterium salmoninarum (see 2 papers)
28% identity, 96% coverage of query (75.5 bits)
GLK_PYRCJ / A3MUZ0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MUZ0 glucokinase (EC 2.7.1.2) from Pyrobaculum calidifontis (see paper)
27% identity, 96% coverage of query (75.1 bits)
2yhwA / Q9Y223 High-resolution crystal structures of n-acetylmannosamine kinase: insights about substrate specificity, activity and inhibitor modelling. (see paper)
28% identity, 82% coverage of query (75.1 bits)
XylR / VIMSS854293 XylR regulator of Xylose utilization, effector Xylose (repressor) from Geobacillus kaustophilus HTA426
27% identity, 83% coverage of query (74.3 bits)
XylR / VIMSS38296 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus subtilis subsp. subtilis str. 168
24% identity, 86% coverage of query (73.9 bits)
Mlc / b1594 DNA-binding transcriptional repressor Mlc from Escherichia coli K-12 substr. MG1655 (see 15 papers)
MLC_ECOLI / P50456 DNA-binding transcriptional repressor Mlc; Making large colonies protein; Membrane linked control from Escherichia coli (strain K12) (see 15 papers)
Mlc / P50456 Transcription factor Mlc (repressor) from Escherichia coli K12 MG1655 (see 4 papers)
mlc / RF|NP_416111.1 protein mlc from Escherichia coli K12 (see 7 papers)
27% identity, 78% coverage of query (73.9 bits)
1z6rA / P50456 Crystal structure of mlc from escherichia coli (see paper)
27% identity, 78% coverage of query (73.9 bits)
NagC / VIMSS548778 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Photorhabdus luminescens TTO1
21% identity, 83% coverage of query (73.2 bits)
H6UH58 glucokinase (EC 2.7.1.2) from Staphylococcus aureus (see paper)
27% identity, 95% coverage of query (72.4 bits)
6jdcA / Q4QP43 Crystal structure of n-acetyl mannosmaine kinase in complex with mannac from haemophilus influenzae
28% identity, 96% coverage of query (72.4 bits)
NanR / VIMSS6257414 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides eggerthii DSM 20697
22% identity, 95% coverage of query (71.6 bits)
6jdbA / Q4QP43 Crystal structure of n-acetyl mannosmaine kinase in complex with mannac-6p and adp from haemophilus influenzae
27% identity, 96% coverage of query (71.6 bits)
6jdhA / A0A2K0XYW4 Crystal structure of n-acetyl mannosmaine kinase from pasteurella multocida
25% identity, 96% coverage of query (71.2 bits)
6jdoA Crystal structure of n-acetyl mannosmaine kinase with amp-pnp from pasteurella multocida
25% identity, 96% coverage of query (71.2 bits)
XylR / P16557 Transcription factor XylR (repressor) from Bacillus subtilis 168 (see 2 papers)
24% identity, 80% coverage of query (69.3 bits)
3vgkB / B1VZT1 Crystal structure of a rok family glucokinase from streptomyces griseus (see paper)
27% identity, 96% coverage of query (68.9 bits)
3vglA Crystal structure of a rok family glucokinase from streptomyces griseus in complex with glucose and amppnp
27% identity, 96% coverage of query (68.9 bits)
B1VZT1 glucokinase (EC 2.7.1.2) from Streptomyces griseus (see 2 papers)
27% identity, 96% coverage of query (68.6 bits)
glk / Q8DVE8 glucokinase subunit (EC 2.7.1.1) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see paper)
28% identity, 95% coverage of query (68.6 bits)
IolR / VIMSS5474541 IolR regulator of Inositol utilization (repressor) from Thermotoga neapolitana DSM 4359
25% identity, 81% coverage of query (67.4 bits)
NagC / b0676 DNA-binding transcriptional dual regulator NagC from Escherichia coli K-12 substr. MG1655 (see 14 papers)
NAGC_ECOLI / P0AF20 N-acetylglucosamine repressor from Escherichia coli (strain K12) (see paper)
NagC / P0AF20 Transcription factor NagC (activator/repressor) from Escherichia coli K12 MG1655 (see 3 papers)
nagC / SP|P0AF20 N-acetylglucosamine repressor from Escherichia coli K12 (see paper)
22% identity, 83% coverage of query (66.6 bits)
XylR / VIMSS822024 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus clausii KSM-K16
22% identity, 85% coverage of query (66.2 bits)
XylR / P70928_BACLI Transcription factor XylR (repressor) from Bacillus licheniformis Gibson 46 (see paper)
24% identity, 86% coverage of query (65.9 bits)
XylR / VIMSS730014 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus licheniformis DSM 13
24% identity, 86% coverage of query (65.9 bits)
A0SZU9 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Lysinibacillus sphaericus (see paper)
26% identity, 94% coverage of query (65.9 bits)
2aa4A / P45425 Crystal structure of escherichia coli putative n-acetylmannosamine kinase, new york structural genomics consortium
29% identity, 82% coverage of query (64.7 bits)
YhcI / b3222 N-acetylmannosamine kinase (EC 2.7.1.60) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
nanK / P45425 N-acetylmannosamine kinase (EC 2.7.1.60) from Escherichia coli (strain K12) (see 5 papers)
NANK_ECOLI / P45425 N-acetylmannosamine kinase; ManNAc kinase; N-acetyl-D-mannosamine kinase; EC 2.7.1.60 from Escherichia coli (strain K12) (see 3 papers)
29% identity, 82% coverage of query (64.7 bits)
NagC / VIMSS2773935 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Reinekea sp. MED297
25% identity, 77% coverage of query (63.5 bits)
NagC / VIMSS339340 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Vibrio parahaemolyticus RIMD 2210633
23% identity, 72% coverage of query (63.5 bits)
Q8RDN7 N-acylmannosamine kinase (EC 2.7.1.60) from Fusobacterium nucleatum subsp. nucleatum (see paper)
26% identity, 96% coverage of query (62.0 bits)
1xc3A / O05510 Structure of a putative fructokinase from bacillus subtilis (see paper)
26% identity, 95% coverage of query (61.6 bits)
3lm9A Crystal structure of fructokinase with adp and fructose bound in the active site
26% identity, 95% coverage of query (61.6 bits)
3eo3A / Q9Y223 Crystal structure of the n-acetylmannosamine kinase domain of human gne protein (see paper)
26% identity, 82% coverage of query (59.7 bits)
3vovB / Q5SLJ4 Crystal structure of rok hexokinase from thermus thermophilus (see paper)
29% identity, 99% coverage of query (59.3 bits)
1woqA / Q7WT42 Crystal structure of inorganic polyphosphate/atp-glucomannokinase from arthrobacter sp. Strain km at 1.8 a resolution (see paper)
27% identity, 76% coverage of query (48.1 bits)
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Lawrence Berkeley National Laboratory