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Searching for up to 100 curated homologs for BWI76_RS23015 FitnessBrowser__Koxy:BWI76_RS23015 (271 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

CBIO_SALTY / Q05596 Cobalt import ATP-binding protein CbiO; Energy-coupling factor transporter ATP-binding protein CbiO; ECF transporter A component CbiO; EC 7.-.-.- from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.23.6 / Q05596 CbiO aka STM2020, component of Cobalt (Co2+) porter from Salmonella typhimurium (see 2 papers)
    85% identity, 100% coverage of query (476 bits)

CBIO_RHOCB / O68106 Cobalt import ATP-binding protein CbiO; Energy-coupling factor transporter ATP-binding protein CbiO; ECF transporter A component CbiO; EC 7.2.2.- from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see 2 papers)
TC 3.A.1.23.8 / O68106 Cobalt import ATP-binding protein CbiO, component of Ni2+/Co2+ uptake porter, CbiMNOQ (CbiM, 222 aas, 5 TMSs; CbiN, 103 aas, 2 TMSs; CbiO, 280 aas, 0 TMSs; CbiQ, 244 aas, 5 TMSs) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
    39% identity, 84% coverage of query (163 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    38% identity, 85% coverage of query (162 bits)

TC 3.A.1.26.10 / TC 3.A.1.26.7 / Q839D5 Cobalt import ATP-binding protein CbiO 1, component of ATP-dependent folic acid uptake porter, FolT/EcfT/EcfA1/EcfA2 from Enterococcus faecalis (see paper)
    36% identity, 91% coverage of query (159 bits)

ECFA1_LACLM / A2RI01 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.- from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 3.A.1.25.4 / A2RI01 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of The biotin uptake system, BioMNY. The 3-d structure of the EcfS subunit, BioY, at 2.1Å resolution is known (Berntsson et al., 2012). BioY and ThiT from L. lactis from Lactococcus lactis subsp. cremoris (strain MG1363)
    35% identity, 91% coverage of query (155 bits)

cbiO2 / Q18CI9 energy-coupling factor transporter ATP-bindind protein 2 from Clostridioides difficile (strain 630) (see 10 papers)
    38% identity, 85% coverage of query (154 bits)

cbiO1 / Q18CJ0 energy-coupling factor transporter ATP-bindind protein 1 from Clostridioides difficile (strain 630) (see 10 papers)
    35% identity, 91% coverage of query (149 bits)

TC 3.A.1.26.10 / TC 3.A.1.26.7 / Q839D4 Cobalt import ATP-binding protein CbiO 2, component of ATP-dependent folic acid uptake porter, FolT/EcfT/EcfA1/EcfA2 from Enterococcus faecalis (see paper)
    34% identity, 88% coverage of query (145 bits)

ECFA1_LACP3 / Q035B2 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.- from Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441) (Lactobacillus paracasei) (see paper)
    37% identity, 87% coverage of query (143 bits)

ECFA2_LACP3 / Q035B3 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; ECF transporter A component EcfA'; EC 3.6.3.- from Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441) (Lactobacillus paracasei) (see paper)
    36% identity, 80% coverage of query (139 bits)

ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    34% identity, 84% coverage of query (137 bits)

ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    33% identity, 97% coverage of query (137 bits)

NIKO_RHOCB / D5AQY6 Nickel import ATP-binding protein NikO; Energy-coupling factor transporter ATP-binding protein NikO; ECF transporter A component NikO; EC 3.6.3.- from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
TC 3.A.1.23.7 / D5AQY6 Nickel import ATP-binding protein NikO, component of Ni2+, Co2+ uptake transporter, NikMNOQ (subunit sizes: NikMN, 347 aas, 9 TMSs; NikQ, 284 aas, 4 TMSs; NikO, 254 aas, 0 TMS from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
    38% identity, 84% coverage of query (137 bits)

ECFA1_LEUMM / Q03ZL6 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) (see 2 papers)
    33% identity, 90% coverage of query (135 bits)

ECFA2_LACLM / A2RI02 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; ECF transporter A component EcfA'; EC 3.6.3.- from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    33% identity, 84% coverage of query (134 bits)

TC 3.A.1.26.9 / TC 3.A.1.28.2 / Q03PY5 Energy-coupling factor transporter ATP-binding protein EcfA1, component of The folate transporter, FolT/EcfAA''T (The 3-d structure is known to 3.0Å resolution (Xu et al. 2013; 4HUQ) from Lactobacillus brevis (strain ATCC 367 / JCM 1170)
    35% identity, 91% coverage of query (134 bits)

5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
    34% identity, 88% coverage of query (133 bits)

8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
    34% identity, 86% coverage of query (131 bits)

8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    33% identity, 88% coverage of query (130 bits)

ECFA2_LEUMM / Q03ZL5 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; ECF transporter A component EcfA'; EC 3.6.3.- from Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) (see 2 papers)
    34% identity, 79% coverage of query (128 bits)

TC 3.A.1.26.9 / TC 3.A.1.28.2 / Q03PY6 Energy-coupling factor transporter ATP-binding protein EcfA2, component of The folate transporter, FolT/EcfAA''T (The 3-d structure is known to 3.0Å resolution (Xu et al. 2013; 4HUQ) from Lactobacillus brevis (strain ATCC 367 / JCM 1170)
    34% identity, 82% coverage of query (127 bits)

LARO_LACPL / Q890D1 Nickel import ATP-binding protein LarO; Energy-coupling factor transporter ATP-binding protein LarO; ECF transporter A component LarO; Nickel transport ATP-binding protein; EC 7.2.2.- from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
    35% identity, 75% coverage of query (125 bits)

8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
    34% identity, 85% coverage of query (124 bits)

5d3mB Folate ecf transporter: amppnp bound state
    34% identity, 85% coverage of query (124 bits)

ECFA1_THEMA / Q9X1Z1 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
TC 3.A.1.25.5 / Q9X1Z1 Energy-coupling factor transporter ATP-binding protein EcfA, component of Biotin/Riboflavin ECF transport system, EcfAA'T/RibU/BioY (Karpowich and Wang 2013). RibU binds riboflavin with high affinity, and the protein-substrate complex is exceptionally stable in solution. The crystal structure of riboflavin-bound RibU reveals an electronegative binding pocket at the extracellular surface in which the substrate is completely buried from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    34% identity, 73% coverage of query (123 bits)

8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    34% identity, 85% coverage of query (122 bits)

4hluC / Q9X1Z1 Structure of the ecfa-a' heterodimer bound to adp (see paper)
    34% identity, 73% coverage of query (119 bits)

TC 3.A.1.20.2 / Q9KLQ5 Fe(3+) ions import ATP-binding protein FbpC, component of Hexose-phosphate transporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    31% identity, 83% coverage of query (117 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    31% identity, 84% coverage of query (113 bits)

TC 3.A.1.26.5 / A7NRG0 ABC transporter related, component of ThiW/CbiQ/CbiO homologues (ThiW: 174 aas; 5 putative TMSs) from Roseiflexus castenholzii (strain DSM 13941 / HLO8)
    34% identity, 86% coverage of query (113 bits)

4zirB Crystal structure of ecfaa' heterodimer bound to amppnp
    34% identity, 73% coverage of query (113 bits)

SM_b21644 ABC transporter for D-Raffinose, ATPase component from Sinorhizobium meliloti 1021
    30% identity, 80% coverage of query (111 bits)

A0A142UTH4 ABC-type polyamine transporter (subunit 4/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    33% identity, 77% coverage of query (110 bits)

YagC / b0262 CP4-6 prophage; ABC transporter ATP-binding protein AfuC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    30% identity, 82% coverage of query (108 bits)

BPHYT_RS24015 L-histidine ABC transporter, ATPase component from Burkholderia phytofirmans PsJN
    32% identity, 82% coverage of query (108 bits)

METN_BACSU / O32169 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32169 MetN (C) (aka YusC), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
    30% identity, 79% coverage of query (107 bits)

Build an alignment

Build an alignment for BWI76_RS23015 and 36 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 3.A.1.14.8 / Q8GRB0 PvuE, component of The iron-vibrioferrin uptake porter from Vibrio parahaemolyticus (see paper)
    29% identity, 85% coverage of query (107 bits)

TC 3.A.1.4.10 / Q8DQH8 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    30% identity, 75% coverage of query (107 bits)

BPHYT_RS07685 ABC transporter for L-Arginine, putative ATPase component from Burkholderia phytofirmans PsJN
    30% identity, 85% coverage of query (106 bits)

TC 3.A.1.3.14 / P39456 TcyC (YckI), component of Uptake system for L-cystine from Bacillus subtilis (see 7 papers)
    29% identity, 83% coverage of query (105 bits)

TC 3.A.1.11.7 / Q97Q42 Spermidine/putrescine import ATP-binding protein PotA, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    31% identity, 80% coverage of query (105 bits)

TC 3.A.1.20.3 / A3N296 Ferric ABC transporter ATP-binding protein, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
    33% identity, 78% coverage of query (104 bits)

TC 3.A.1.3.23 / Q9HU32 Probable ATP-binding component of ABC transporter, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    31% identity, 82% coverage of query (103 bits)

7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
    33% identity, 79% coverage of query (102 bits)

4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
    31% identity, 75% coverage of query (100 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    33% identity, 77% coverage of query (100 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    33% identity, 77% coverage of query (99.0 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    33% identity, 77% coverage of query (99.0 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    33% identity, 77% coverage of query (99.0 bits)

4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
    31% identity, 75% coverage of query (98.6 bits)

FhuC / b0151 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FhuC / P07821 iron(III) hydroxamate ABC transporter ATP binding subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see paper)
FHUC_ECOLI / P07821 Iron(3+)-hydroxamate import ATP-binding protein FhuC; Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC; EC 7.2.2.16 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.14.3 / P07821 FhuC aka B0151, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 6 papers)
fhuC / GB|BAB96727.2 ferrichrome transport ATP-binding protein FhuC; EC 3.6.3.34 from Escherichia coli K12 (see 8 papers)
    31% identity, 82% coverage of query (97.8 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    31% identity, 79% coverage of query (96.7 bits)

ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
    28% identity, 79% coverage of query (95.9 bits)

4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
    27% identity, 82% coverage of query (94.4 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    29% identity, 79% coverage of query (93.2 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    29% identity, 79% coverage of query (93.2 bits)

2olkA Abc protein artp in complex with adp-beta-s
    29% identity, 79% coverage of query (93.2 bits)

2oljA Abc protein artp in complex with adp/mg2+
    29% identity, 79% coverage of query (93.2 bits)

ABCA2_HUMAN / Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see 10 papers)
    28% identity, 77% coverage of query (92.8 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    30% identity, 83% coverage of query (92.8 bits)

6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
    27% identity, 85% coverage of query (89.7 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    27% identity, 82% coverage of query (89.4 bits)

6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
    33% identity, 82% coverage of query (88.6 bits)

3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    33% identity, 82% coverage of query (88.6 bits)

3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    33% identity, 82% coverage of query (88.6 bits)

7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
    33% identity, 82% coverage of query (88.6 bits)

4q9iA P-glycoprotein cocrystallised with qz-ala
    33% identity, 82% coverage of query (88.6 bits)

4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
    33% identity, 82% coverage of query (88.6 bits)

4xwkA P-glycoprotein co-crystallized with bde-100
    33% identity, 82% coverage of query (88.6 bits)

6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
    28% identity, 76% coverage of query (88.2 bits)

6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
    28% identity, 76% coverage of query (88.2 bits)

P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
    29% identity, 82% coverage of query (88.2 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    29% identity, 77% coverage of query (88.2 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    29% identity, 77% coverage of query (88.2 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    29% identity, 77% coverage of query (88.2 bits)

ECSA_BACSU / P55339 ABC-type transporter ATP-binding protein EcsA from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.143.1 / P55339 ABC-type transporter ATP-binding protein EcsA, component of The exoprotein (including α-amylase) secretion system, EcsAB(C) (Leskelä et al., 1999). Also may play roles in sporulation, competence (Leskelä et al., 1996) and transformation using purified DNA (Takeno et al., 2011). An involvement of EcsC in transport is not established, but it is homologous to the C-terminus of the P-type ATPase, 3.A.3.31.2 from Bacillus subtilis (strain 168) (see 3 papers)
    26% identity, 91% coverage of query (87.8 bits)

5koyA Mouse pgp 34 linker deleted bound with atp
    33% identity, 82% coverage of query (87.0 bits)

HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
    29% identity, 84% coverage of query (87.0 bits)

6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
    33% identity, 82% coverage of query (87.0 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    27% identity, 87% coverage of query (86.7 bits)

1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
    29% identity, 84% coverage of query (86.7 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    27% identity, 87% coverage of query (86.7 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    27% identity, 87% coverage of query (86.7 bits)

6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
    32% identity, 82% coverage of query (86.3 bits)

7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
    32% identity, 79% coverage of query (85.9 bits)

6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
    33% identity, 82% coverage of query (85.9 bits)

7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
    32% identity, 78% coverage of query (85.9 bits)

7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
    32% identity, 82% coverage of query (85.9 bits)

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
    27% identity, 82% coverage of query (85.9 bits)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
    27% identity, 82% coverage of query (85.9 bits)

7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
    32% identity, 82% coverage of query (85.9 bits)

7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
    32% identity, 82% coverage of query (85.9 bits)

7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
    32% identity, 82% coverage of query (85.9 bits)

7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
    32% identity, 82% coverage of query (85.9 bits)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
    27% identity, 82% coverage of query (85.9 bits)

6b89A E. Coli lptb in complex with adp and novobiocin
    27% identity, 82% coverage of query (85.9 bits)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
    27% identity, 82% coverage of query (85.9 bits)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
    27% identity, 82% coverage of query (85.9 bits)

ABCA4_HUMAN / P78363 Retinal-specific phospholipid-transporting ATPase ABCA4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM proteinv; RmP; Retinal-specific ATP-binding cassette transporter; Stargardt disease protein; EC 7.6.2.1 from Homo sapiens (Human) (see 38 papers)
TC 3.A.1.211.2 / P78363 The retinal-specific ABC transporter (RIM protein, ABCR or ABCA4) (Stargardt's disease protein, involved in retinal/macular degeneration) in the rod outer segment. Changes in the oligomeric state of the nucleotide binding domains of ABCR are coupled to ATP hydrolysis and might represent a signal for the TMDs of ABCR to export the bound substrate (Biswas-Fiss 2006). The ABCA4 porter flips N-retinylidene-phosphatidylethanolamine, a product generated from the photobleaching of rhodopsin, from the lumen to the cytoplasmic side of disc membranes following the photobleaching of rhodopsin, insuring that retinoids do not accumulate in disc membranes (Molday, 2007; Molday et al. 2009; Tsybovsky et al. 2013). It also transports several vitamin A derivatives (Sun, 2011) and phosphatidylethanolamine in the same direction. Mutations, known to cause Stargardt disease, decrease N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine transport activities (Quazi et al. 2012). It functions as an inwardly directed retinoid flippase in the visual cycle from Homo sapiens (Human) (see 28 papers)
    28% identity, 76% coverage of query (85.5 bits)

8f5bA / P78363 Human abca4 structure in complex with amp-pnp
    28% identity, 76% coverage of query (85.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory