Searching for up to 100 curated homologs for BWI76_RS23175 FitnessBrowser__Koxy:BWI76_RS23175 (370 a.a.)
Found high-coverage hits (≥70%) to 64 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pduQ / Q9XDN0 propanol dehydrogenase (EC 1.1.1.1) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
PDUQ_SALTY / Q9XDN0 1-propanol dehydrogenase PduQ; Propanediol utilization protein PduQ; EC 1.1.-.- from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
96% identity, 100% coverage of query (731 bits)
PDUQ_CITFR / B1VB76 1-propanol dehydrogenase PduQ; Propanediol utilization protein PduQ; EC 1.1.-.- from Citrobacter freundii (see paper)
83% identity, 100% coverage of query (636 bits)
A0A0H3W5K4 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum (see paper)
I3VSF1 alcohol dehydrogenase (EC 1.1.1.1); L-lactate dehydrogenase (EC 1.1.1.27); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum (see paper)
42% identity, 99% coverage of query (307 bits)
A0A0H3W5V0 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Thermoanaerobacterium saccharolyticum (see paper)
42% identity, 99% coverage of query (305 bits)
B0KBJ9 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter pseudethanolicus (see paper)
41% identity, 99% coverage of query (300 bits)
B0K4A2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter sp. X514 (see 2 papers)
41% identity, 99% coverage of query (300 bits)
Q0PH30 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter ethanolicus (see paper)
41% identity, 99% coverage of query (295 bits)
3zdrA Structure of the alcohol dehydrogenase (adh) domain of a bifunctional adhe dehydrogenase from geobacillus thermoglucosidasius ncimb 11955 (see paper)
41% identity, 96% coverage of query (285 bits)
A0A1D3TRQ6 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Anaerobium acetethylicum (see paper)
39% identity, 99% coverage of query (271 bits)
A0A0H3W5U9 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Acetivibrio thermocellus (see 3 papers)
A3DCI2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Acetivibrio thermocellus (see 4 papers)
39% identity, 98% coverage of query (254 bits)
adhE2 / Q9ANR5 aldehyde dehydrogenase/alcohol dehydrogenase (EC 1.2.1.57) from Clostridium acetobutylicum (see 4 papers)
35% identity, 98% coverage of query (237 bits)
ADHE_STRPN / A0A0H2URT2 Aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.3 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see paper)
37% identity, 99% coverage of query (233 bits)
ADHE_STRP2 / A0A0H2ZM56 Aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.3 from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
37% identity, 99% coverage of query (232 bits)
adh1 / P13604 NADPH-dependent butanol dehydrogenase (EC 1.1.1.2) from Clostridium saccharobutylicum (see 3 papers)
adh1 / GB|AAA83520.1 NADPH-dependent butanol dehydrogenase; EC 1.1.1.1 from Clostridium saccharobutylicum (see paper)
35% identity, 99% coverage of query (231 bits)
ADH1 / A8JI07 alcohol dehydrogenase / acetaldehyde dehydrogenase (EC 1.2.1.10; EC 1.1.1.1) from Chlamydomonas reinhardtii (see 2 papers)
38% identity, 84% coverage of query (223 bits)
Q1RS84 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Chlamydomonas reinhardtii (see paper)
38% identity, 84% coverage of query (223 bits)
6scgA Structure of adhe form 1
37% identity, 92% coverage of query (223 bits)
adh2 / GB|AAA81906.1 aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica (see paper)
AAA81906.1 alcohol dehydrogenase 2 from Entamoeba histolytica (see paper)
37% identity, 95% coverage of query (222 bits)
ADH2_ENTH1 / Q24803 Aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM) (see 2 papers)
37% identity, 95% coverage of query (221 bits)
7bvpA / P0A9Q7 Adhe spirosome in extended conformation (see paper)
36% identity, 92% coverage of query (218 bits)
AdhE / b1241 fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655 (see 62 papers)
adhE / P0A9Q7 fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli (strain K12) (see 64 papers)
ADHE_ECOLI / P0A9Q7 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) (see 13 papers)
ADHE_ECO57 / P0A9Q8 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli O157:H7 (see 2 papers)
P0A9Q7 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Escherichia coli (see paper)
adhE / MB|P0A9Q7 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Escherichia coli K12 (see 12 papers)
36% identity, 92% coverage of query (218 bits)
6tqmA Escherichia coli adhe structure in its compact conformation
36% identity, 92% coverage of query (218 bits)
YffV / b2453 putative alcohol dehydrogenase EutG from Escherichia coli K-12 substr. MG1655 (see 2 papers)
EUTG_ECOLI / P76553 Probable alcohol dehydrogenase EutG; Ethanolamine utilization protein EutG; EC 1.1.1.1 from Escherichia coli (strain K12) (see paper)
eutG / GB|AAC75506.2 ethanolamine utilization protein eutG; EC 1.1.-.- from Escherichia coli K12 (see 3 papers)
39% identity, 99% coverage of query (217 bits)
ADH_THEBA / A0A0S1X9S7 Alcohol dehydrogenase; EC 1.1.1.1 from Thermococcus barophilus (see paper)
34% identity, 99% coverage of query (212 bits)
I3E949 methanol dehydrogenase (EC 1.1.1.244) from Bacillus methanolicus (see 2 papers)
38% identity, 86% coverage of query (211 bits)
EUTG_SALTY / P41795 Probable alcohol dehydrogenase EutG; Ethanolamine utilization protein EutG; EC 1.1.1.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 5 papers)
37% identity, 99% coverage of query (209 bits)
B1HX72 methanol dehydrogenase (EC 1.1.1.244) from Lysinibacillus sphaericus (see paper)
35% identity, 99% coverage of query (209 bits)
I3E2P9 methanol dehydrogenase (EC 1.1.1.244) from Bacillus methanolicus (see 4 papers)
37% identity, 86% coverage of query (207 bits)
rhaZ / Q8ZKS2 L-lactaldehyde reductase (EC 1.1.1.77) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
38% identity, 97% coverage of query (201 bits)
I3DVX6 methanol dehydrogenase (EC 1.1.1.244) from Bacillus methanolicus (see paper)
36% identity, 86% coverage of query (200 bits)
adhB / P0DJA2 alcohol dehydrogenase II monomer (EC 1.1.1.1) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see 8 papers)
ADH2_ZYMMO / P0DJA2 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see 2 papers)
P0DJA2 alcohol dehydrogenase (EC 1.1.1.1) from Zymomonas mobilis subsp. mobilis (see paper)
35% identity, 96% coverage of query (199 bits)
3owoA / P0DJA2 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 with and without NAD cofactor (see paper)
35% identity, 96% coverage of query (199 bits)
3ox4A Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor
35% identity, 96% coverage of query (199 bits)
mdh / P31005 NAD-dependent methanol dehydrogenase monomer (EC 1.1.1.244) from Bacillus methanolicus (see paper)
MEDH_BACMT / P31005 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus (see 6 papers)
P31005 methanol dehydrogenase (EC 1.1.1.244) from Bacillus methanolicus (see paper)
mdh methanol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus (see paper)
34% identity, 95% coverage of query (197 bits)
I3DX19 methanol dehydrogenase (EC 1.1.1.244) from Bacillus methanolicus (see paper)
33% identity, 99% coverage of query (197 bits)
A0A0Q2QQL1 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Thermococcus thioreducens (see paper)
6c75A / A0A0Q2QQL1 Structure of iron containing alcohol dehydrogenase from thermococcus thioreducens in a monoclinic crystal form (see paper)
33% identity, 98% coverage of query (196 bits)
6c75B Structure of iron containing alcohol dehydrogenase from thermococcus thioreducens in a monoclinic crystal form
33% identity, 98% coverage of query (196 bits)
O58517 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Pyrococcus horikoshii (see paper)
32% identity, 98% coverage of query (190 bits)
I3DTP7 methanol dehydrogenase (EC 1.1.1.244) from Bacillus methanolicus (see paper)
34% identity, 95% coverage of query (189 bits)
BT3767 L-lactaldehyde reductase FucO (EC 1.1.1.77) from Bacteroides thetaiotaomicron VPI-5482
36% identity, 86% coverage of query (188 bits)
YiaY / b3589 L-threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
yiaY / P37686 L-threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli (strain K12) (see 5 papers)
36% identity, 90% coverage of query (186 bits)
3bfjA / Q7WRJ3 Crystal structure analysis of 1,3-propanediol oxidoreductase (see paper)
34% identity, 93% coverage of query (177 bits)
1rrmA Crystal structure of lactaldehyde reductase
33% identity, 97% coverage of query (167 bits)
7qlqAAA Lactaldehyde reductase
32% identity, 97% coverage of query (167 bits)
2bi4A Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli
33% identity, 97% coverage of query (167 bits)
FucO / b2799 L-1,2-propanediol oxidoreductase (EC 1.1.1.77) from Escherichia coli K-12 substr. MG1655 (see 22 papers)
fucO / P0A9S1 L-1,2-propanediol oxidoreductase (EC 1.1.1.77) from Escherichia coli (strain K12) (see 23 papers)
FUCO_ECOLI / P0A9S1 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) (see paper)
33% identity, 97% coverage of query (167 bits)
5br4A / P0A9S1 E. Coli lactaldehyde reductase (fuco) m185c mutant (see paper)
33% identity, 97% coverage of query (166 bits)
7qlgAAA Lactaldehyde reductase
32% identity, 97% coverage of query (166 bits)
6jkpA Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+
35% identity, 72% coverage of query (148 bits)
6jkoA / A0A0A7I0A5 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense (see paper)
35% identity, 72% coverage of query (148 bits)
4HBDH_CUPNE / Q59104 4-hydroxybutyrate dehydrogenase; 4HbD; Gamma-hydroxybutyrate dehydrogenase; GHBDH; EC 1.1.1.61 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) (see 2 papers)
Q59104 4-hydroxybutyrate dehydrogenase (EC 1.1.1.61) from Cupriavidus necator (see paper)
gbd / PRF|2104199G 4-hydroxybutyrate dehydrogenase; EC 1.1.1.61 from Cupriavidus necator (see paper)
31% identity, 91% coverage of query (140 bits)
Build an alignment for BWI76_RS23175 and 51 homologs with ≥ 30% identity
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5yvmA / A0A133UP32 Crystal structure of the archaeal halo-thermophilic red sea brine pool alcohol dehydrogenase adh/d1 bound to nzq (see paper)
28% identity, 97% coverage of query (129 bits)
5yvrA Crystal structure of the h277a mutant of adh/d1, an archaeal halo- thermophilic red sea brine pool alcohol dehydrogenase
28% identity, 97% coverage of query (125 bits)
3rf7A / Q12MB1 Crystal structure of an iron-containing alcohol dehydrogenase (sden_2133) from shewanella denitrificans os-217 at 2.12 a resolution
28% identity, 74% coverage of query (102 bits)
5k8cA / Q8EEB0 X-ray structure of kdnb, 3-deoxy-alpha-d-manno-octulosonate 8-oxidase, from shewanella oneidensis (see paper)
27% identity, 74% coverage of query (88.2 bits)
8i29A Crystal structure of butanol dehydrogenase a (yqdh) in complex with nadh from fusobacterium nucleatum
25% identity, 72% coverage of query (87.0 bits)
7fjgA / Q8R612 Crystal structure of butanol dehydrogenase a (yqdh) in complex with partial nadh from fusobacterium nucleatum
25% identity, 72% coverage of query (87.0 bits)
3jzdA / Q46TQ1 Crystal structure of putative alcohol dehedrogenase (yp_298327.1) from ralstonia eutropha jmp134 at 2.10 a resolution
29% identity, 76% coverage of query (85.5 bits)
YqhD / b3011 NADPH-dependent aldehyde reductase YqhD (EC 1.1.1.2) from Escherichia coli K-12 substr. MG1655 (see 35 papers)
yqhD / Q46856 NADPH-dependent aldehyde reductase YqhD (EC 1.1.1.21; EC 1.1.1.2) from Escherichia coli (strain K12) (see 38 papers)
YQHD_ECOLI / Q46856 Alcohol dehydrogenase YqhD; EC 1.1.1.2 from Escherichia coli (strain K12) (see paper)
Q46856 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Escherichia coli (see paper)
yqhD / RF|NP_417484 alcohol dehydrogenase yqhD; EC 1.1.1.- from Escherichia coli K12 (see 5 papers)
26% identity, 87% coverage of query (83.6 bits)
1oj7B Structural genomics, unknown function crystal structure of e. Coli k-12 yqhd
25% identity, 87% coverage of query (81.6 bits)
1oj7A / Q46856 Structural genomics, unknown function crystal structure of e. Coli k-12 yqhd (see paper)
25% identity, 87% coverage of query (81.6 bits)
7w9zA Crystal structure of bacillus subtilis yugj in complex with NADP and nitrate
24% identity, 73% coverage of query (77.4 bits)
7w9yA Crystal structure of bacillus subtilis yugj in complex with NADP and nickel (see paper)
24% identity, 73% coverage of query (77.4 bits)
1vljB / Q9WZS7 Crystal structure of nadh-dependent butanol dehydrogenase a (tm0820) from thermotoga maritima at 1.78 a resolution
25% identity, 84% coverage of query (73.9 bits)
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Lawrence Berkeley National Laboratory