Searching for up to 100 curated homologs for BWI76_RS23415 FitnessBrowser__Koxy:BWI76_RS23415 (413 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

E0IXR1 protein-Npi-phosphohistidine-sucrose phosphotransferase (EC 2.7.1.211) from Escherichia coli (see paper)
    40% identity, 98% coverage of query (297 bits)

CSCB_ECOLX / P30000 Sucrose permease; Sucrose transport protein from Escherichia coli (see 3 papers)
TC 2.A.1.5.3 / P30000 Sucrose:H+ symporter, CscB, also transports maltose (Peng et al. 2009). CscB recognizes not just sucrose but also fructose and lactulose, but glucopyranosides are not transported and do not inhibit sucrose transport from Escherichia coli (see paper)
    40% identity, 98% coverage of query (296 bits)

RAFB_ECOLX / P16552 Raffinose permease; Raf permease from Escherichia coli (see 2 papers)
TC 2.A.1.5.2 / P16552 Raffinose:H+ symporter, RafB, can be mutated to transport maltose from Escherichia coli (see paper)
    42% identity, 91% coverage of query (290 bits)

lactose/melibiose:H⁺ symporter / b0343 lactose permease from Escherichia coli K-12 substr. MG1655 (see 52 papers)
lacY / P02920 lactose permease from Escherichia coli (strain K12) (see 112 papers)
LACY_ECOLI / P02920 Lactose permease; Lactose-proton symport from Escherichia coli (strain K12) (see 7 papers)
P02920 protein-Npi-phosphohistidine-lactose phosphotransferase (EC 2.7.1.207) from Escherichia coli (see paper)
TC 2.A.1.5.1 / P02920 β- and α-galactopyranoside:H+ from Escherichia coli (see 12 papers)
    42% identity, 88% coverage of query (278 bits)

2y5yA Crystal structure of lacy in complex with an affinity inactivator
    42% identity, 88% coverage of query (273 bits)

6vbgB / P02920 Lactose permease complex with thiodigalactoside and nanobody 9043 (see paper)
    41% identity, 88% coverage of query (268 bits)

4zyrA Crystal structure of e. Coli lactose permease g46w/g262w bound to p- nitrophenyl alpha-d-galactopyranoside (alpha-npg)
    41% identity, 88% coverage of query (265 bits)

MELY_ENTCC / P96517 Melibiose permease; Melibiose transporter MelY from Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) (see 4 papers)
TC 2.A.1.5.4 / P96517 Melibiose:H+ symporter, MelY (Shinnick et al., 2003). Transports melibiose and lactose, but not TMG, which does however bind to the transporter from Enterobacter cloacae (see 2 papers)
    42% identity, 90% coverage of query (261 bits)

cscB / CAD26969.1 sucrose permease from Bifidobacterium animalis (see paper)
    33% identity, 97% coverage of query (242 bits)

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