Sites on a Tree

 

Searching for up to 100 curated homologs for BWI76_RS24610 BWI76_RS24610 dihydroxyacetone kinase (549 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q1KLC3 glycerone kinase (EC 2.7.1.29) from Citrobacter freundii (see paper)
dhaK / ABF06666.1 dihydroxyacetone kinase from Citrobacter freundii (see paper)
    85% identity, 100% coverage of query (939 bits)

DHAK_CITFR / P45510 Dihydroxyacetone kinase; DHA kinase; Glycerone kinase; EC 2.7.1.29 from Citrobacter freundii (see 2 papers)
dhaK / GB|AAB48843.1 glycerone kinase; EC 2.7.1.29 from Citrobacter freundii (see 2 papers)
dhaK / AAB48843.1 dihydroxyacetone kinase from Citrobacter freundii (see 4 papers)
    84% identity, 100% coverage of query (921 bits)

A0A023T745 glycerone kinase (EC 2.7.1.29) from Klebsiella pneumoniae (see paper)
    86% identity, 100% coverage of query (917 bits)

1un9A / P45510 Crystal structure of the dihydroxyacetone kinase from c. Freundii in complex with amp-pnp and mg2+ (see paper)
    82% identity, 100% coverage of query (890 bits)

A0A143T1M7 glycerone kinase (EC 2.7.1.29) from Shimwellia blattae (see paper)
    77% identity, 100% coverage of query (812 bits)

TKFC / Q3LXA3 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) (EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15) from Homo sapiens (see paper)
TKFC_HUMAN / Q3LXA3 Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15 from Homo sapiens (Human) (see 5 papers)
Q3LXA3 triokinase (EC 2.7.1.28); glycerone kinase (EC 2.7.1.29); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) from Homo sapiens (see 5 papers)
    40% identity, 97% coverage of query (309 bits)

Q8VC30 triokinase (EC 2.7.1.28) from Mus musculus (see paper)
    38% identity, 99% coverage of query (293 bits)

Dak / Q4KLZ6 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) (EC 2.7.1.29; EC 4.6.1.15) from Rattus norvegicus (see 3 papers)
TKFC_RAT / Q4KLZ6 Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15 from Rattus norvegicus (Rat) (see 2 papers)
    38% identity, 99% coverage of query (292 bits)

TKFC_PIG / F1RKQ4 Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15 from Sus scrofa (Pig) (see paper)
    39% identity, 97% coverage of query (284 bits)

DAK / O60017 dihydroxyacetone kinase subunit (EC 2.7.1.29) from Pichia angusta (see 2 papers)
    34% identity, 100% coverage of query (259 bits)

A0A0H3J0E7 glycerone kinase (EC 2.7.1.29) from Clostridium pasteurianum (see paper)
    32% identity, 99% coverage of query (245 bits)

DAK1 / P54838 dihydroxyacetone kinase 1 (EC 2.7.1.29) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
DAK1_YEAST / P54838 Dihydroxyacetone kinase 1; DHA kinase 1; Glycerone kinase 1; Triokinase 1; Triose kinase 1; EC 2.7.1.28; EC 2.7.1.29 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P54838 glycerone kinase (EC 2.7.1.29) from Saccharomyces cerevisiae (see paper)
    34% identity, 97% coverage of query (241 bits)

A0A1D3TV19 glycerone kinase (EC 2.7.1.29) from Anaerobium acetethylicum (see paper)
    31% identity, 99% coverage of query (238 bits)

O74192 glycerone kinase (EC 2.7.1.29) from Komagataella pastoris (see paper)
    32% identity, 99% coverage of query (237 bits)

DAK1_SCHPO / O13902 Dihydroxyacetone kinase 1; DHA kinase 1; Glycerone kinase 1; Triokinase 1; Triose kinase 1; EC 2.7.1.28; EC 2.7.1.29 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
O13902 glycerone kinase (EC 2.7.1.29) from Schizosaccharomyces pombe (see paper)
dak1 / RF|NP_593241.1 dihydroxyacetone kinase Dak1; EC 2.7.1.29 from Schizosaccharomyces pombe (see 3 papers)
    34% identity, 89% coverage of query (233 bits)

dak2 / O74215 dihydroxyacetone kinase 2 (EC 2.7.1.29) from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (see paper)
    32% identity, 97% coverage of query (223 bits)

lerK / A0R758 L-erythrulose 1-kinase (EC 2.7.1.209) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see 2 papers)
LERK_MYCS2 / A0R758 L-erythrulose 1-kinase; EC 2.7.1.209 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
A0R758 L-erythrulose 1-kinase (EC 2.7.1.209) from Mycolicibacterium smegmatis (see paper)
    34% identity, 99% coverage of query (220 bits)

DAK2 / P43550 dihydroxyacetone kinase 2 (EC 2.7.1.29) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
P43550 glycerone kinase (EC 2.7.1.29) from Saccharomyces cerevisiae (see paper)
    32% identity, 99% coverage of query (219 bits)

derK / A0QXE4 D-erythrulose kinase (EC 2.7.1.210) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see paper)
DERK_MYCS2 / A0QXE4 D-erythrulose kinase; EC 2.7.1.210 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
A0QXE4 D-erythrulose 4-kinase (EC 2.7.1.210) from Mycolicibacterium smegmatis (see paper)
    31% identity, 99% coverage of query (176 bits)

LERK_PECAS / Q6D8V6 L-erythrulose kinase; EC 2.7.1.209 from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) (see paper)
    31% identity, 99% coverage of query (176 bits)

Build an alignment

Build an alignment for BWI76_RS24610 and 20 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory