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Searching for up to 100 curated homologs for BWI76_RS24860 FitnessBrowser__Koxy:BWI76_RS24860 (304 a.a.)

Found high-coverage hits (≥70%) to 34 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q8VS15 D-tagatose-1-phosphate kinase (EC 2.7.1.234) from Klebsiella oxytoca (see paper)
    97% identity, 100% coverage of query (605 bits)

tagK / Q65EY9 D-tagatose-1-phosphate kinase (EC 2.7.1.234) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see 3 papers)
Q65EY9 D-tagatose-1-phosphate kinase (EC 2.7.1.234) from Bacillus licheniformis (see paper)
    39% identity, 100% coverage of query (207 bits)

lacC / P0A0B8 D-tagatose-6-phosphate kinase subunit (EC 2.7.1.144) from Staphylococcus aureus (strain MW2) (see 2 papers)
P0A0B9 tagatose-6-phosphate kinase (EC 2.7.1.144) from Staphylococcus aureus (see paper)
    30% identity, 100% coverage of query (135 bits)

2jg1A / P0A0B9 Structure of staphylococcus aureus d-tagatose-6-phosphate kinase with cofactor and substrate (see paper)
    30% identity, 100% coverage of query (135 bits)

2jg1C Structure of staphylococcus aureus d-tagatose-6-phosphate kinase with cofactor and substrate
    30% identity, 100% coverage of query (135 bits)

2jgvB Structure of staphylococcus aureus d-tagatose-6-phosphate kinase in complex with adp
    30% identity, 100% coverage of query (135 bits)

Build an alignment

Build an alignment for BWI76_RS24860 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2f02A / Q833W9 Crystal structure of lacc from enterococcus faecalis in complex with atp
    28% identity, 100% coverage of query (121 bits)

Psest_3354 1-phosphofructokinase (EC 2.7.1.56) from Pseudomonas stutzeri RCH2
    28% identity, 94% coverage of query (116 bits)

LACC_LACLL / P23391 Tagatose-6-phosphate kinase; Phosphotagatokinase; EC 2.7.1.144 from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see paper)
    28% identity, 100% coverage of query (114 bits)

AO356_07330 1-phosphofructokinase (EC 2.7.1.56) from Pseudomonas fluorescens FW300-N2C3
    31% identity, 94% coverage of query (111 bits)

PfkB / b1723 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
pfkB / P06999 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli (strain K12) (see 40 papers)
PFKB_ECOLI / P06999 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; 6-phosphofructokinase isozyme II; Phosphohexokinase 2; EC 2.7.1.11 from Escherichia coli (strain K12) (see 4 papers)
P06999 6-phosphofructokinase (EC 2.7.1.11) from Escherichia coli (see 2 papers)
3n1cA / P06999 Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with fructose-6-phosphate (see paper)
    27% identity, 91% coverage of query (108 bits)

3uqeA Crystal structure of the phosphofructokinase-2 mutant y23d from escherichia coli
    27% identity, 91% coverage of query (108 bits)

3uqdB Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    27% identity, 91% coverage of query (108 bits)

3uqdA Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    27% identity, 91% coverage of query (108 bits)

3cqdA Structure of the tetrameric inhibited form of phosphofructokinase-2 from escherichia coli
    27% identity, 91% coverage of query (108 bits)

K1PF_VIBCH / Q9KM71 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
    28% identity, 100% coverage of query (104 bits)

Fpk / b2168 1-phosphofructokinase (EC 2.7.1.56) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
fruK / P0AEW9 1-phosphofructokinase (EC 2.7.1.56) from Escherichia coli (strain K12) (see 8 papers)
K1PF_ECOLI / P0AEW9 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Escherichia coli (strain K12) (see paper)
fruK / RF|NP_416673 1-phosphofructokinase from Escherichia coli K12 (see 2 papers)
    27% identity, 88% coverage of query (101 bits)

K1PF_HALVD / D4GYE6 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GYE6 1-phosphofructokinase (EC 2.7.1.56) from Haloferax volcanii (see paper)
    29% identity, 94% coverage of query (99.0 bits)

G4SW45 diphosphate-fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90) from Methylotuvimicrobium alcaliphilum (see paper)
    27% identity, 99% coverage of query (90.1 bits)

PFKB_MYCTO / P9WID2 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; Phosphofructokinase B; Phosphohexokinase 2; Tagatose-6-phosphate kinase; EC 2.7.1.11; EC 2.7.1.144 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see paper)
PFKB_MYCTU / P9WID3 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; Phosphofructokinase B; Phosphohexokinase 2; Tagatose-6-phosphate kinase; EC 2.7.1.11; EC 2.7.1.144 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
    26% identity, 96% coverage of query (88.6 bits)

2ajrA / Q9WZT5 Crystal structure of possible 1-phosphofructokinase (ec 2.7.1.56) (tm0828) from thermotoga maritima at 2.46 a resolution
    26% identity, 100% coverage of query (84.7 bits)

K1PF_XANCP / P23354 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    29% identity, 85% coverage of query (79.0 bits)

K1PF_MYCGE / Q49396 Putative 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) (Mycoplasmoides genitalium) (see paper)
    24% identity, 86% coverage of query (75.9 bits)

3ie7A / Q929S5 The crystal structure of phosphofructokinase (lin2199) from listeria innocua in complex with atp at 1.6a
    24% identity, 100% coverage of query (70.9 bits)

3julA Crystal structure of listeria innocua d-tagatose-6-phosphate kinase bound with substrate
    24% identity, 100% coverage of query (64.7 bits)

RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
    23% identity, 75% coverage of query (62.4 bits)

BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
    26% identity, 79% coverage of query (57.0 bits)

KDGK_THETE / Q704D0 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermoproteus tenax (see paper)
kdgK / CAF18464.1 2-Keto-3-deoxy-gluconate kinase from Thermoproteus tenax (see paper)
    28% identity, 78% coverage of query (53.9 bits)

1gqtB / P0A9J6 Activation of ribokinase by monovalent cations (see paper)
    26% identity, 77% coverage of query (53.5 bits)

RbsK / b3752 ribokinase (EC 2.7.1.15) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
rbsK / P0A9J6 ribokinase (EC 2.7.1.15) from Escherichia coli (strain K12) (see 19 papers)
RBSK_ECOLI / P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 5 papers)
rbsK / RF|NP_418208 ribokinase from Escherichia coli K12 (see 4 papers)
    26% identity, 77% coverage of query (53.1 bits)

1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121
    26% identity, 77% coverage of query (53.1 bits)

6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
    23% identity, 80% coverage of query (52.8 bits)

RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
    23% identity, 80% coverage of query (52.8 bits)

Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
    25% identity, 80% coverage of query (48.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory