Searching for up to 100 curated homologs for BWI76_RS26220 FitnessBrowser__Koxy:BWI76_RS26220 (368 a.a.)
Found high-coverage hits (≥70%) to 40 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DHAS_SALTY / P0A1F8 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
93% identity, 100% coverage of query (706 bits)
Dap / b3433 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
asd / P0A9Q9 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Escherichia coli (strain K12) (see 12 papers)
DHAS_ECOLI / P0A9Q9 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Escherichia coli (strain K12) (see 5 papers)
1gl3A / P0A9Q9 Aspartate beta-semialdehyde dehydrogenase in complex with NADP and substrate analogue s-methyl cysteine sulfoxide (see paper)
asd / RF|NP_417891 aspartate-semialdehyde dehydrogenase from Escherichia coli K12 (see 2 papers)
93% identity, 100% coverage of query (705 bits)
C5BB06 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Edwardsiella ictaluri (see paper)
83% identity, 98% coverage of query (623 bits)
DHAS_HAEIN / P44801 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
P44801 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Haemophilus influenzae (see 4 papers)
72% identity, 100% coverage of query (571 bits)
1pquA / P44801 Crystal structure of the h277n mutant of aspartate semialdehyde dehydrogenase from haemophilus influenzae bound with NADP, s-methyl cysteine sulfoxide and cacodylate (see paper)
72% identity, 100% coverage of query (569 bits)
1tb4A Crystal structure of aspartate-semialdehyde dehydrogenase from haemophilus influenzae with a bound periodate
70% identity, 100% coverage of query (547 bits)
1ta4A Crystal structure of aspartate-semialdehyde dehydrogenase from haemophilus influenzae with a bound arsenate
70% identity, 100% coverage of query (547 bits)
1nx6A Crystal structure of aspartate semialdehyde dehydrogenase from haemophilus influenzae as a tetrahedral hemithiocetal reaction intermediate with phosphate at 2.15 a
70% identity, 100% coverage of query (547 bits)
1pqpA Crystal structure of the c136s mutant of aspartate semialdehyde dehydrogenase from haemophilus influenzae bound with aspartate semialdehyde and phosphate
70% identity, 100% coverage of query (543 bits)
DHAS_PSEAE / Q51344 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
68% identity, 100% coverage of query (534 bits)
5bntC / Q51344 X-ray crystal structure of a aspartate-semialdehyde dehydrogenase bound to NADP from pseudomonas aeruginosa
68% identity, 100% coverage of query (533 bits)
asd / Q9KQG2 aspartate-β-semialdehyde dehydrogenase subunit (EC 1.2.1.11) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 3 papers)
DHAS1_VIBCH / Q9KQG2 Aspartate-semialdehyde dehydrogenase 1; ASA dehydrogenase 1; ASADH 1; Aspartate-beta-semialdehyde dehydrogenase 1; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
Q9KQG2 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Vibrio cholerae (see 3 papers)
3pzrA / Q9KQG2 Crystals structure of aspartate beta-semialdehyde dehydrogenase from vibrio cholerae with NADP and product of s-carbamoyl-l-cysteine (see paper)
67% identity, 98% coverage of query (526 bits)
4r5mA Crystal structure of vc-aspartate beta-semialdehyde-dehydrogenase with NADP and 4-nitro-2-phosphono-benzoic acid
67% identity, 98% coverage of query (526 bits)
1mb4A Crystal structure of aspartate semialdehyde dehydrogenase from vibrio cholerae with NADP and s-methyl-l-cysteine sulfoxide
67% identity, 98% coverage of query (526 bits)
asd / AAB51626.1 aspartate semialdehyde dehydrogenase from Pseudomonas aeruginosa (see paper)
67% identity, 100% coverage of query (518 bits)
7tcmA / V5VGT0 Crystal structure of aspartate-semialdehyde dehydrogenase from acinetobacter baumannii in complex with NADP
66% identity, 99% coverage of query (515 bits)
Q5NHM4 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Francisella tularensis subsp. tularensis (see paper)
49% identity, 99% coverage of query (374 bits)
Build an alignment for BWI76_RS26220 and 17 homologs with ≥ 30% identity
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asd / Q04797 aspartate semialdehyde dehydrogenase subunit (EC 1.2.1.11) from Bacillus subtilis (strain 168) (see paper)
27% identity, 96% coverage of query (83.2 bits)
Q04797 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Bacillus subtilis (strain 168)
27% identity, 96% coverage of query (83.2 bits)
3pylC Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with d-2,3-diaminopropionate (see paper)
26% identity, 96% coverage of query (79.7 bits)
4r5hA Crystal structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide-adenine-dinucleotide-phosphate and 3-carboxy-propenyl- phthalic acid
26% identity, 96% coverage of query (79.7 bits)
4r4jA Crystal structure of complex sp_asadh with 3-carboxypropyl-phthalic acid and nicotinamide adenine dinucleotide phosphate
26% identity, 96% coverage of query (79.7 bits)
3pyxB Crystals structure of aspartate beta-semialdehyde dehydrogenase complex with NADP and 2-aminoterephthalate
26% identity, 96% coverage of query (79.7 bits)
3q11A Crystals structure of aspartate beta-semialdehyde dehydrogenase from streptococcus pneumoniae with NADP and aspartyl beta- difluorophosphonate
26% identity, 96% coverage of query (79.7 bits)
4r54A Complex crystal structure of sp-aspartate-semialdehyde-dehydrogenase with 3-carboxy-ethyl-phthalic acid
26% identity, 96% coverage of query (79.7 bits)
4r41A Complex crystal structure of 4-nitro-2-phosphono-benzoic acid with sp- aspartate-semialdehyde dehydrogenase and nicotinamide-dinucleotide
26% identity, 96% coverage of query (79.7 bits)
4r3nA Crystal structure of the ternary complex of sp-asadh with NADP and 1, 2,3-benzenetricarboxylic acid
26% identity, 96% coverage of query (79.7 bits)
3q1lA Crystals structure of aspartate beta-semialdehyde dehydrogenase from streptococcus pneumoniae with cysteamine bound covalently to cys 128
26% identity, 96% coverage of query (79.7 bits)
3pwsA Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with 2',5'-adenosine diphosphate and d-2- aminoadipate
26% identity, 96% coverage of query (79.7 bits)
3pwkA Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with 2',5'-adenosine diphosphate and d-2- aminoadipate
26% identity, 96% coverage of query (79.7 bits)
2gz3A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with NADP and aspartate- semialdehyde
26% identity, 96% coverage of query (79.7 bits)
2gz2A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with 2',5'-adp
26% identity, 96% coverage of query (79.7 bits)
2gz1A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with NADP
26% identity, 96% coverage of query (79.7 bits)
4r51A Crystal complex structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide adenine dinucleotide phosphate and phthalic acid
26% identity, 96% coverage of query (79.7 bits)
DHAS2_VIBCH / P23247 Aspartate-semialdehyde dehydrogenase 2; ASA dehydrogenase 2; ASADH 2; Aspartate-beta-semialdehyde dehydrogenase 2; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
25% identity, 80% coverage of query (79.3 bits)
2r00C / P23247 Crystal structure of aspartate semialdehyde dehydrogenase ii complexed with asa from vibrio cholerae (see paper)
25% identity, 80% coverage of query (79.3 bits)
AT1G14810 / Q8VYI4 aspartate semialdehyde dehydrogenase (EC 1.2.1.11) from Arabidopsis thaliana (see paper)
25% identity, 96% coverage of query (73.6 bits)
Q8KQ27 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Streptomyces clavuligerus (see paper)
28% identity, 74% coverage of query (73.2 bits)
3tz6A / P9WNX5 Crystal structure of aspartate semialdehyde dehydrogenase complexed with inhibitor smcs (cys) and phosphate from mycobacterium tuberculosis h37rv (see paper)
27% identity, 96% coverage of query (70.5 bits)
DHAS_MYCTU / P9WNX5 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WNX5 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Mycobacterium tuberculosis (see 5 papers)
27% identity, 96% coverage of query (70.5 bits)
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Lawrence Berkeley National Laboratory