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Searching for up to 100 curated homologs for BWI76_RS26270 FitnessBrowser__Koxy:BWI76_RS26270 (163 a.a.)

Found high-coverage hits (≥70%) to 28 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YhhY / b3441 N-acetyltransferase YhhY from Escherichia coli K-12 substr. MG1655 (see 4 papers)
AAAT_ECOLI / P46854 L-amino acid N-acetyltransferase AaaT; L-methionine N-acetyltransferase; L-phenylalanine N-acetyltransferase; EC 2.3.1.-; EC 2.3.1.53 from Escherichia coli (strain K12) (see 2 papers)
    68% identity, 99% coverage of query (237 bits)

2vi7C / Q9I3W7 Structure of a putative acetyltransferase (pa1377)from pseudomonas aeruginosa (see paper)
    43% identity, 96% coverage of query (128 bits)

Q9I3W7 amino-acid N-acetyltransferase (EC 2.3.1.1) from Pseudomonas aeruginosa (see paper)
    43% identity, 96% coverage of query (126 bits)

Build an alignment

Build an alignment for BWI76_RS26270 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2i79A / A0A0H2URR1 The crystal structure of the acetyltransferase of gnat family from streptococcus pneumoniae
    27% identity, 98% coverage of query (77.4 bits)

3ld2B / Q8DRZ8 The crystal structure of smu.2055 from streptococcus mutans ua159
    28% identity, 83% coverage of query (65.5 bits)

4jwpA / Q2YRK4 Crystal structure of ribosomal-protein-alanine n-acetyltransferase from brucella melitensis in complex with acetyl coa
    27% identity, 97% coverage of query (52.0 bits)

Q9HM13 N-terminal amino-acid Nalpha-acetyltransferase NatA (EC 2.3.1.255) from Thermoplasma acidophilum (see paper)
    30% identity, 96% coverage of query (51.2 bits)

A0A0H2XGJ0 diamine N-acetyltransferase (EC 2.3.1.57) from Staphylococcus aureus (see paper)
    30% identity, 71% coverage of query (50.4 bits)

4pv6G / Q97CT7 Crystal structure analysis of ard1 from thermoplasma volcanium (see paper)
    29% identity, 96% coverage of query (49.3 bits)

4pv6A Crystal structure analysis of ard1 from thermoplasma volcanium
    29% identity, 96% coverage of query (49.3 bits)

ATDA_VIBCH / Q9KL03 Spermidine N(1)-acetyltransferase; SAT; Spermidine/spermine N(1)-acetyltransferase; SSAT; EC 2.3.1.57 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 3 papers)
Q9KL03 diamine N-acetyltransferase (EC 2.3.1.57) from Vibrio cholerae (see 2 papers)
    23% identity, 99% coverage of query (48.9 bits)

6e1xC / Q9KL03 Crystal structure of product-bound complex of spermidine/spermine n- acetyltransferase speg
    25% identity, 99% coverage of query (48.9 bits)

6e1xA Crystal structure of product-bound complex of spermidine/spermine n- acetyltransferase speg
    23% identity, 99% coverage of query (48.9 bits)

4r87A Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with coa and spermine
    23% identity, 99% coverage of query (48.9 bits)

4r57A Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with acetyl-coa
    23% identity, 99% coverage of query (48.9 bits)

4nczA Spermidine n-acetyltransferase from vibrio cholerae in complex with 2- [n-cyclohexylamino]ethane sulfonate.
    23% identity, 99% coverage of query (48.9 bits)

4mi4A Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with spermine
    23% identity, 99% coverage of query (48.9 bits)

4mhdA Crystal structure of spermidine n-acetyltransferase from vibrio cholerae in complex with spermidine
    23% identity, 99% coverage of query (48.9 bits)

6cx8A Crystal structure of spermidine/spermine n-acetyltransferase speg from vibrio cholerae in complex with manganese ions.
    23% identity, 99% coverage of query (48.9 bits)

5cnpB X-ray crystal structure of spermidine n1-acetyltransferase from vibrio cholerae.
    23% identity, 99% coverage of query (48.9 bits)

4r3lA Crystal structure of ard1 n-terminal acetyltransferase from sulfolobus solfataricus bound to substrate peptide fragment and coa
    26% identity, 97% coverage of query (43.5 bits)

4r3kA Crystal structure of ard1 n-terminal acetyltransferase from sulfolobus solfataricus bound to coa
    26% identity, 97% coverage of query (43.5 bits)

4lx9A Archaeal amino-terminal acetyltransferase (nat) bound to acetyl coenzyme a
    26% identity, 97% coverage of query (43.5 bits)

4r9mA Crystal structure of spermidine n-acetyltransferase from escherichia coli
    25% identity, 91% coverage of query (43.5 bits)

NAT_SACS2 / Q980R9 N-alpha-acetyltransferase; NAT; Amino-terminal acetyltransferase; N-terminal acetyltransferase; EC 2.3.1.255; EC 2.3.1.258 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 4 papers)
Q980R9 N-terminal amino-acid Nalpha-acetyltransferase NatA (EC 2.3.1.255) from Saccharolobus solfataricus (see paper)
    26% identity, 97% coverage of query (43.5 bits)

5c88A / Q980R9 Crystal structure of ard1 n-terminal acetyltransferase from sulfolobus solfataricus in monoclinic form (see paper)
    26% identity, 97% coverage of query (43.1 bits)

6c37A Mycobacterium smegmatis rimj in complex with coa-disulfide
    28% identity, 94% coverage of query (42.4 bits)

6c32A / A0R3G9 Mycobacterium smegmatis rimj with accoa
    28% identity, 94% coverage of query (42.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory