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Searching for up to 100 curated homologs for BWI76_RS27020 BWI76_RS27020 xylulokinase (484 a.a.)

Found high-coverage hits (≥70%) to 72 curated proteins.

Removed hits that are identical to the query, leaving 71

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

XylB / b3564 xylulokinase (EC 2.7.1.17) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
xylB / P09099 xylulokinase (EC 2.7.1.17) from Escherichia coli (strain K12) (see 8 papers)
XYLB_ECOLI / P09099 Xylulose kinase; XK; Xylulokinase; 1-deoxy-D-xylulokinase; EC 2.7.1.17; EC 2.7.1.- from Escherichia coli (strain K12) (see 2 papers)
xylB / GB|AAC76588.1 xylulokinase; EC 2.7.1.17 from Escherichia coli K12 (see paper)
    85% identity, 100% coverage of query (824 bits)

2itmA / P09099 Crystal structure of the e. Coli xylulose kinase complexed with xylulose (see paper)
    83% identity, 100% coverage of query (799 bits)

SMc03164 Xylulose kinase (EC 2.7.1.17) from Sinorhizobium meliloti 1021
    51% identity, 90% coverage of query (422 bits)

Dshi_1997 Xylulose kinase (EC 2.7.1.17) from Dinoroseobacter shibae DFL-12
    48% identity, 99% coverage of query (399 bits)

PGA1_c14010 Xylulose kinase (EC 2.7.1.17) from Phaeobacter inhibens BS107
    49% identity, 85% coverage of query (363 bits)

C7NMH3 xylulokinase (EC 2.7.1.17) from Halorhabdus utahensis (see paper)
    43% identity, 99% coverage of query (355 bits)

Q9WXX1 xylulokinase (EC 2.7.1.17) from Thermotoga maritima (see paper)
    36% identity, 99% coverage of query (333 bits)

XYLB_LEVBR / P35850 Xylulose kinase; Xylulokinase; EC 2.7.1.17 from Levilactobacillus brevis (Lactobacillus brevis) (see paper)
    34% identity, 98% coverage of query (259 bits)

mtlY / Q4KC52 xylulose kinase (EC 2.7.1.17) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    36% identity, 85% coverage of query (232 bits)

Pf6N2E2_805 Xylulose kinase (EC 2.7.1.17) from Pseudomonas fluorescens FW300-N2E2
    35% identity, 84% coverage of query (207 bits)

AO356_27695 Xylulose kinase (EC 2.7.1.17) from Pseudomonas fluorescens FW300-N2C3
    34% identity, 85% coverage of query (207 bits)

Q8NU35 xylulokinase (EC 2.7.1.17) from Corynebacterium glutamicum (see paper)
    34% identity, 90% coverage of query (179 bits)

Build an alignment

Build an alignment for BWI76_RS27020 and 12 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Echvi_1875 xylulokinase (EC 2.7.1.17) from Echinicola vietnamensis KMM 6221, DSM 17526
    28% identity, 99% coverage of query (165 bits)

3i8bA / A1A0I0 The crystal structure of xylulose kinase from bifidobacterium adolescentis
    30% identity, 90% coverage of query (164 bits)

BT0792 xylulokinase (EC 2.7.1.17) from Bacteroides thetaiotaomicron VPI-5482
    28% identity, 95% coverage of query (163 bits)

3ll3B The crystal structure of ligand bound xylulose kinase from lactobacillus acidophilus
    27% identity, 99% coverage of query (161 bits)

3ll3A / Q5FM28 The crystal structure of ligand bound xylulose kinase from lactobacillus acidophilus
    27% identity, 99% coverage of query (160 bits)

3kzbA / Q7NWW7 Crystal structure of xylulokinase from chromobacterium violaceum
    29% identity, 94% coverage of query (136 bits)

6k76A / O93623 Glycerol kinase form thermococcus kodakarensis, complex structure with substrate.
    26% identity, 90% coverage of query (135 bits)

GLPK_THEKO / O93623 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 2 papers)
O93623 glycerol kinase (EC 2.7.1.30) from Thermococcus kodakarensis (see 2 papers)
    26% identity, 90% coverage of query (132 bits)

3ge1A / Q5HGD2 2.7 angstrom crystal structure of glycerol kinase (glpk) from staphylococcus aureus in complex with adp and glycerol
    24% identity, 95% coverage of query (124 bits)

Q92NH0 erythritol kinase (D-erythritol 1-phosphate-forming) (EC 2.7.1.215) from Sinorhizobium meliloti (see paper)
    27% identity, 86% coverage of query (124 bits)

Q5HGD2 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Staphylococcus aureus (strain COL)
    24% identity, 95% coverage of query (124 bits)

SM_b21009 Glycerol kinase (EC 2.7.1.30) from Sinorhizobium meliloti 1021
    25% identity, 85% coverage of query (119 bits)

O86033 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
    25% identity, 85% coverage of query (119 bits)

6udeB / A0A077EJ65 Crystal structure of glycerol kinase from elizabethkingia anophelis nuhp1 in complex with adp and glycerol
    24% identity, 95% coverage of query (118 bits)

A6TFR2 glycerol kinase (EC 2.7.1.30) from Klebsiella pneumoniae subsp. pneumoniae (see paper)
    24% identity, 96% coverage of query (115 bits)

GlpK / b3926 glycerol kinase (EC 2.7.1.30) from Escherichia coli K-12 substr. MG1655 (see 82 papers)
glpK / P0A6F3 glycerol kinase (EC 2.7.1.30) from Escherichia coli (strain K12) (see 80 papers)
GLPK_ECOLI / P0A6F3 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Escherichia coli (strain K12) (see 15 papers)
glpK glycerol kinase; EC 2.7.1.30 from Escherichia coli K12 (see 13 papers)
    24% identity, 96% coverage of query (115 bits)

1glfO Crystal structures of escherichia coli glycerol kinase and the mutant a65t in an inactive tetramer: conformational changes and implications for allosteric regulation
    24% identity, 96% coverage of query (115 bits)

1bo5O Crystal structure of the complex between escherichia coli glycerol kinase and the allosteric regulator fructose 1,6-bisphosphate.
    24% identity, 96% coverage of query (115 bits)

1gldG Cation promoted association (cpa) of a regulatory and target protein is controlled by phosphorylation
    24% identity, 96% coverage of query (115 bits)

1glcG Cation promoted association (cpa) of a regulatory and target protein is controlled by phosphorylation
    24% identity, 96% coverage of query (115 bits)

1glbG Structure of the regulatory complex of escherichia coli iiiglc with glycerol kinase
    24% identity, 96% coverage of query (115 bits)

1bu6Y / P0A6F3 Crystal structures of escherichia coli glycerol kinase and the mutant a65t in an inactive tetramer: conformational changes and implications for allosteric regulation (see paper)
    24% identity, 96% coverage of query (114 bits)

P18157 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Bacillus subtilis (strain 168)
    23% identity, 95% coverage of query (114 bits)

glpK / CAA74429.1 glycerol kinase from Bacillus subtilis (see 3 papers)
    23% identity, 95% coverage of query (113 bits)

2w41B / Q8IDI4 Crystal structure of plasmodium falciparum glycerol kinase with adp (see paper)
    23% identity, 90% coverage of query (113 bits)

2w40A Crystal structure of plasmodium falciparum glycerol kinase with bound glycerol
    23% identity, 90% coverage of query (112 bits)

1gllO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion
    24% identity, 96% coverage of query (112 bits)

1gljO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion
    24% identity, 96% coverage of query (112 bits)

1bwfO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion
    24% identity, 96% coverage of query (112 bits)

XylK / b3580 L-xylulose kinase (EC 2.7.1.53) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
lyxK / P37677 L-xylulose kinase (EC 2.7.1.53) from Escherichia coli (strain K12) (see 5 papers)
LYXK_ECOLI / P37677 L-xylulose/3-keto-L-gulonate kinase; L-xylulokinase; 3-dehydro-L-gulonate kinase; EC 2.7.1.-; EC 2.7.1.53 from Escherichia coli (strain K12) (see 2 papers)
    23% identity, 95% coverage of query (111 bits)

PS417_05575 Glycerol kinase (EC 2.7.1.30) from Pseudomonas simiae WCS417
    26% identity, 95% coverage of query (110 bits)

aplK / Q6D5T8 apulose kinase (EC 2.7.1.233) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (see paper)
APLK_PECAS / Q6D5T8 Apulose kinase; EC 2.7.1.233 from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) (see paper)
Q6D5T8 apulose kinase (EC 2.7.1.233) from Pectobacterium atrosepticum (see paper)
    27% identity, 89% coverage of query (109 bits)

GLPK_HALVD / D4GYI5 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; EC 2.7.1.30 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    25% identity, 84% coverage of query (107 bits)

FucK / b2803 L-fuculokinase (EC 2.7.1.51) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
fucK / P11553 L-fuculokinase (EC 2.7.1.51) from Escherichia coli (strain K12) (see 6 papers)
FUCK_ECOLI / P11553 L-fuculokinase; L-fuculose kinase; EC 2.7.1.51 from Escherichia coli (strain K12) (see 3 papers)
    26% identity, 84% coverage of query (106 bits)

BWI76_RS22930 L-fuculokinase (EC 2.7.1.51) from Klebsiella michiganensis M5al
    25% identity, 83% coverage of query (105 bits)

P74260 glycerol kinase (EC 2.7.1.30) from Synechocystis sp. PCC 6803 (see paper)
    24% identity, 85% coverage of query (104 bits)

YdeV / b1511 autoinducer-2 kinase (EC 2.7.1.189) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
lsrK / P77432 autoinducer-2 kinase (EC 2.7.1.189) from Escherichia coli (strain K12) (see 25 papers)
LSRK_ECOLI / P77432 Autoinducer-2 kinase; AI-2 kinase; EC 2.7.1.189 from Escherichia coli (strain K12) (see 3 papers)
P77432 autoinducer-2 kinase (EC 2.7.1.189) from Escherichia coli (see 2 papers)
lsrK / RF|NP_416028 autoinducer 2 kinase lsrK from Escherichia coli K12 (see 3 papers)
    24% identity, 99% coverage of query (104 bits)

Dshi_3420 Glycerol kinase (EC 2.7.1.30) from Dinoroseobacter shibae DFL-12
    26% identity, 89% coverage of query (103 bits)

GLPK_ENTFA / O34154 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Enterococcus faecalis (strain ATCC 700802 / V583) (see 2 papers)
    24% identity, 90% coverage of query (98.2 bits)

5ya2A Crystal structure of lsrk-hpr complex with adp
    23% identity, 97% coverage of query (94.4 bits)

5ya1A / P77432 Crystal structure of lsrk-hpr complex with atp (see paper)
    23% identity, 97% coverage of query (93.6 bits)

6zq4F / G0SAG9 Crystal structure of chaetomium thermophilum glycerol kinase in complex with substrate in p1 space group (see paper)
    26% identity, 86% coverage of query (91.7 bits)

3h3nX / O34153 Glycerol kinase h232r with glycerol (see paper)
    23% identity, 90% coverage of query (90.1 bits)

GLPK_ENTCA / O34153 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Enterococcus casseliflavus (Enterococcus flavescens) (see 3 papers)
    23% identity, 90% coverage of query (89.7 bits)

6jafA Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with ppi (pyrophosphatase reaction)
    23% identity, 85% coverage of query (88.6 bits)

6j9qA Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with amp-pnp.
    23% identity, 85% coverage of query (88.6 bits)

5aziA / D3KVM3 Crystal structure of glycerol kinase from trypanosoma brucei gambiense complexed with 4np (see paper)
    23% identity, 85% coverage of query (88.6 bits)

3wxlA Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with adp, mg2+, and glycerol
    23% identity, 85% coverage of query (88.6 bits)

3wxjB Crystal structure of trypanosoma brucei gambiense glycerol kinase in complex with glycerol 3-phosphate
    23% identity, 85% coverage of query (88.6 bits)

GLPK_TRYBB / Q9NJP9 Glycerol kinase, glycosomal; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase; EC 2.7.1.30 from Trypanosoma brucei brucei (see 2 papers)
D3KVM3 glycerol kinase (EC 2.7.1.30) from Trypanosoma brucei gambiense (see 3 papers)
D3KVM4 glycerol kinase (EC 2.7.1.30) from Trypanosoma brucei rhodesiense (see paper)
Q9NJP9 glycerol kinase (EC 2.7.1.30) from Trypanosoma brucei brucei (see 2 papers)
    23% identity, 85% coverage of query (88.6 bits)

5gn6A Crystal structure of glycerol kinase from trypanosoma brucei gambiense complexed with cumarin derivative-17b
    23% identity, 85% coverage of query (88.2 bits)

5gn5A Crystal structure of glycerol kinase from trypanosoma brucei gambiense complexed with cumarin derivative-17
    23% identity, 85% coverage of query (88.2 bits)

3l0qA / Q665C6 The crystal structure of xlylulose kinase from yersinia pseudotuberculosis
    21% identity, 85% coverage of query (77.4 bits)

3qdkA / Q9KBQ3 Structural insight on mechanism and diverse substrate selection strategy of ribulokinase (see paper)
    22% identity, 71% coverage of query (62.8 bits)

2uytA Structure of l-rhamnulose kinase in complex with adp and beta-l- rhamnulose.
    23% identity, 71% coverage of query (53.9 bits)

2cglA Crystal structure of l-rhamnulose kinase from escherichia coli in complex with l-fructose, adp and a modeled atp gamma phosphate.
    23% identity, 71% coverage of query (53.9 bits)

2cgjA / P32171 Crystal structure of l-rhamnulose kinase from escherichia coli in complex with l-fructose and adp. (see paper)
    23% identity, 71% coverage of query (53.9 bits)

RHAB_ECOUT / Q1R415 Rhamnulokinase; Rhamnulose kinase; EC 2.7.1.5 from Escherichia coli (strain UTI89 / UPEC) (see paper)
    23% identity, 71% coverage of query (52.8 bits)

RhaB / b3904 rhamnulokinase (EC 2.7.1.5) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
rhaB / P32171 rhamnulokinase (EC 2.7.1.5) from Escherichia coli (strain K12) (see 5 papers)
RHAB_ECOLI / P32171 L-Rhamnulokinase; RhaB; RhuK; ATP:L-rhamnulose phosphotransferase; L-rhamnulose 1-kinase; Rhamnulose kinase; EC 2.7.1.5 from Escherichia coli (strain K12) (see 6 papers)
    24% identity, 71% coverage of query (51.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory