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Searching for up to 100 curated homologs for BWI76_RS27515 BWI76_RS27515 glycerol kinase (503 a.a.)

Found high-coverage hits (≥70%) to 67 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A6TFR2 glycerol kinase (EC 2.7.1.30) from Klebsiella pneumoniae subsp. pneumoniae (see paper)
    98% identity, 100% coverage of query (1031 bits)

GlpK / b3926 glycerol kinase (EC 2.7.1.30) from Escherichia coli K-12 substr. MG1655 (see 82 papers)
glpK / P0A6F3 glycerol kinase (EC 2.7.1.30) from Escherichia coli (strain K12) (see 80 papers)
GLPK_ECOLI / P0A6F3 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Escherichia coli (strain K12) (see 15 papers)
glpK glycerol kinase; EC 2.7.1.30 from Escherichia coli K12 (see 13 papers)
    94% identity, 100% coverage of query (992 bits)

1bu6Y / P0A6F3 Crystal structures of escherichia coli glycerol kinase and the mutant a65t in an inactive tetramer: conformational changes and implications for allosteric regulation (see paper)
    93% identity, 99% coverage of query (984 bits)

1glfO Crystal structures of escherichia coli glycerol kinase and the mutant a65t in an inactive tetramer: conformational changes and implications for allosteric regulation
    94% identity, 99% coverage of query (984 bits)

1bo5O Crystal structure of the complex between escherichia coli glycerol kinase and the allosteric regulator fructose 1,6-bisphosphate.
    94% identity, 99% coverage of query (984 bits)

1gllO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion
    93% identity, 99% coverage of query (966 bits)

1gljO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion
    93% identity, 99% coverage of query (966 bits)

1bwfO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion
    93% identity, 99% coverage of query (966 bits)

1gldG Cation promoted association (cpa) of a regulatory and target protein is controlled by phosphorylation
    92% identity, 99% coverage of query (960 bits)

1glcG Cation promoted association (cpa) of a regulatory and target protein is controlled by phosphorylation
    92% identity, 99% coverage of query (960 bits)

1glbG Structure of the regulatory complex of escherichia coli iiiglc with glycerol kinase
    92% identity, 99% coverage of query (960 bits)

PS417_05575 Glycerol kinase (EC 2.7.1.30) from Pseudomonas simiae WCS417
    73% identity, 100% coverage of query (784 bits)

glpK / CAA74429.1 glycerol kinase from Bacillus subtilis (see 3 papers)
    62% identity, 98% coverage of query (669 bits)

P18157 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Bacillus subtilis (strain 168)
    62% identity, 98% coverage of query (669 bits)

GLPK_THETH / O66131 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Thermus thermophilus (see paper)
    64% identity, 98% coverage of query (663 bits)

GLPK_THEAQ / Q9WX53 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Thermus aquaticus (see paper)
    64% identity, 98% coverage of query (657 bits)

3ge1A / Q5HGD2 2.7 angstrom crystal structure of glycerol kinase (glpk) from staphylococcus aureus in complex with adp and glycerol
    61% identity, 97% coverage of query (655 bits)

Q5HGD2 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Staphylococcus aureus (strain COL)
    61% identity, 97% coverage of query (654 bits)

6udeB / A0A077EJ65 Crystal structure of glycerol kinase from elizabethkingia anophelis nuhp1 in complex with adp and glycerol
    61% identity, 99% coverage of query (644 bits)

GLPK_ENTCA / O34153 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Enterococcus casseliflavus (Enterococcus flavescens) (see 3 papers)
    57% identity, 98% coverage of query (603 bits)

3h3nX / O34153 Glycerol kinase h232r with glycerol (see paper)
    57% identity, 97% coverage of query (601 bits)

GLPK_ENTFA / O34154 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Enterococcus faecalis (strain ATCC 700802 / V583) (see 2 papers)
    58% identity, 98% coverage of query (600 bits)

GLPK_THEKO / O93623 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 2 papers)
O93623 glycerol kinase (EC 2.7.1.30) from Thermococcus kodakarensis (see 2 papers)
    56% identity, 98% coverage of query (571 bits)

6k76A / O93623 Glycerol kinase form thermococcus kodakarensis, complex structure with substrate.
    56% identity, 98% coverage of query (560 bits)

GLPK_HALVD / D4GYI5 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; EC 2.7.1.30 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    56% identity, 99% coverage of query (553 bits)

D0VZG4 glycerol kinase (EC 2.7.1.30) from Cellulomonas sp. (see paper)
    53% identity, 99% coverage of query (538 bits)

SM_b21009 Glycerol kinase (EC 2.7.1.30) from Sinorhizobium meliloti 1021
    53% identity, 97% coverage of query (537 bits)

O86033 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
    53% identity, 97% coverage of query (537 bits)

P9WPK1 glycerol kinase (EC 2.7.1.30) from Mycobacterium tuberculosis (see paper)
    53% identity, 98% coverage of query (527 bits)

Dshi_3420 Glycerol kinase (EC 2.7.1.30) from Dinoroseobacter shibae DFL-12
    52% identity, 97% coverage of query (523 bits)

GLPK_ARATH / Q9M8L4 Glycerol kinase; Glycerokinase; ATP:glycerol 3-phosphotransferase; Protein GLYCEROL INSENSITIVE 1; Protein NONHOST RESISTANCE TO P. S. PHASEOLICOLA 1; EC 2.7.1.30 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    48% identity, 97% coverage of query (444 bits)

GLPK_MOUSE / Q64516 Glycerol kinase; Glycerokinase; ATP:glycerol 3-phosphotransferase; EC 2.7.1.30 from Mus musculus (Mouse) (see 2 papers)
    47% identity, 97% coverage of query (443 bits)

GLPK_RAT / Q63060 Glycerol kinase; Glycerokinase; ATP-stimulated glucocorticoid-receptor translocation promoter; ASTP; ATP:glycerol 3-phosphotransferase; EC 2.7.1.30 from Rattus norvegicus (Rat) (see paper)
    47% identity, 97% coverage of query (443 bits)

P74260 glycerol kinase (EC 2.7.1.30) from Synechocystis sp. PCC 6803 (see paper)
    48% identity, 91% coverage of query (442 bits)

Q0IID9 glycerol kinase (EC 2.7.1.30) from Bos taurus (see paper)
    47% identity, 97% coverage of query (441 bits)

GLPK_HUMAN / P32189 Glycerol kinase; Glycerokinase; ATP:glycerol 3-phosphotransferase; EC 2.7.1.30 from Homo sapiens (Human) (see 5 papers)
    47% identity, 97% coverage of query (438 bits)

GLPK2_HUMAN / Q14410 Glycerol kinase 2; GK 2; Glycerokinase 2; ATP:glycerol 3-phosphotransferase 2; Glycerol kinase, testis specific 2; EC 2.7.1.30 from Homo sapiens (Human) (see 2 papers)
    46% identity, 97% coverage of query (437 bits)

GLPK2_MOUSE / Q9WU65 Glycerol kinase 2; GK 2; Glycerokinase 2; ATP:glycerol 3-phosphotransferase 2; Glycerol kinase, testis specific 2; EC 2.7.1.30 from Mus musculus (Mouse) (see 3 papers)
Q9WU65 glycerol kinase (EC 2.7.1.30) from Mus musculus (see paper)
    46% identity, 97% coverage of query (437 bits)

B0M0V1 glycerol kinase (EC 2.7.1.30) from Bombyx mori (see paper)
    44% identity, 98% coverage of query (437 bits)

GLPK_TRYBB / Q9NJP9 Glycerol kinase, glycosomal; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase; EC 2.7.1.30 from Trypanosoma brucei brucei (see 2 papers)
D3KVM3 glycerol kinase (EC 2.7.1.30) from Trypanosoma brucei gambiense (see 3 papers)
D3KVM4 glycerol kinase (EC 2.7.1.30) from Trypanosoma brucei rhodesiense (see paper)
Q9NJP9 glycerol kinase (EC 2.7.1.30) from Trypanosoma brucei brucei (see 2 papers)
    45% identity, 97% coverage of query (412 bits)

5aziA / D3KVM3 Crystal structure of glycerol kinase from trypanosoma brucei gambiense complexed with 4np (see paper)
    45% identity, 97% coverage of query (412 bits)

5gn6A Crystal structure of glycerol kinase from trypanosoma brucei gambiense complexed with cumarin derivative-17b
    45% identity, 97% coverage of query (412 bits)

5gn5A Crystal structure of glycerol kinase from trypanosoma brucei gambiense complexed with cumarin derivative-17
    45% identity, 97% coverage of query (412 bits)

6jafA Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with ppi (pyrophosphatase reaction)
    45% identity, 97% coverage of query (412 bits)

6j9qA Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with amp-pnp.
    45% identity, 97% coverage of query (412 bits)

3wxlA Crystal structure of trypanosoma brucei gambiense glycerol kinase complex with adp, mg2+, and glycerol
    45% identity, 97% coverage of query (412 bits)

3wxjB Crystal structure of trypanosoma brucei gambiense glycerol kinase in complex with glycerol 3-phosphate
    45% identity, 97% coverage of query (412 bits)

Q75T26 glycerol kinase (EC 2.7.1.30) from Trypanosoma congolense (see paper)
    45% identity, 97% coverage of query (410 bits)

B0I530 glycerol kinase (EC 2.7.1.30) from Trypanosoma vivax (see paper)
    44% identity, 97% coverage of query (407 bits)

B0I1G6 glycerol kinase (EC 2.7.1.30) from Bombyx mori (see paper)
    43% identity, 99% coverage of query (402 bits)

2w41B / Q8IDI4 Crystal structure of plasmodium falciparum glycerol kinase with adp (see paper)
    41% identity, 97% coverage of query (369 bits)

2w40A Crystal structure of plasmodium falciparum glycerol kinase with bound glycerol
    41% identity, 97% coverage of query (369 bits)

6zq4F / G0SAG9 Crystal structure of chaetomium thermophilum glycerol kinase in complex with substrate in p1 space group (see paper)
    42% identity, 98% coverage of query (367 bits)

B0Y6Y4 glycerol kinase (EC 2.7.1.30) from Aspergillus fumigatus (see paper)
    41% identity, 99% coverage of query (354 bits)

glcA putative glycerol kinase from Emericella nidulans (see paper)
    41% identity, 99% coverage of query (353 bits)

aplK / Q6D5T8 apulose kinase (EC 2.7.1.233) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (see paper)
APLK_PECAS / Q6D5T8 Apulose kinase; EC 2.7.1.233 from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) (see paper)
Q6D5T8 apulose kinase (EC 2.7.1.233) from Pectobacterium atrosepticum (see paper)
    39% identity, 97% coverage of query (340 bits)

Q6ZS86 glycerol kinase (EC 2.7.1.30) from Homo sapiens (see paper)
    33% identity, 98% coverage of query (317 bits)

Build an alignment

Build an alignment for BWI76_RS27515 and 57 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

C7NMH3 xylulokinase (EC 2.7.1.17) from Halorhabdus utahensis (see paper)
    28% identity, 91% coverage of query (174 bits)

Q9WXX1 xylulokinase (EC 2.7.1.17) from Thermotoga maritima (see paper)
    26% identity, 88% coverage of query (156 bits)

3ll3B The crystal structure of ligand bound xylulose kinase from lactobacillus acidophilus
    23% identity, 93% coverage of query (126 bits)

3ll3A / Q5FM28 The crystal structure of ligand bound xylulose kinase from lactobacillus acidophilus
    23% identity, 93% coverage of query (125 bits)

XylB / b3564 xylulokinase (EC 2.7.1.17) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
xylB / P09099 xylulokinase (EC 2.7.1.17) from Escherichia coli (strain K12) (see 8 papers)
XYLB_ECOLI / P09099 Xylulose kinase; XK; Xylulokinase; 1-deoxy-D-xylulokinase; EC 2.7.1.17; EC 2.7.1.- from Escherichia coli (strain K12) (see 2 papers)
xylB / GB|AAC76588.1 xylulokinase; EC 2.7.1.17 from Escherichia coli K12 (see paper)
    24% identity, 93% coverage of query (113 bits)

5ya2A Crystal structure of lsrk-hpr complex with adp
    26% identity, 95% coverage of query (111 bits)

5ya1A / P77432 Crystal structure of lsrk-hpr complex with atp (see paper)
    26% identity, 95% coverage of query (110 bits)

2itmA / P09099 Crystal structure of the e. Coli xylulose kinase complexed with xylulose (see paper)
    24% identity, 93% coverage of query (105 bits)

3kzbA / Q7NWW7 Crystal structure of xylulokinase from chromobacterium violaceum
    22% identity, 91% coverage of query (56.6 bits)

3i8bA / A1A0I0 The crystal structure of xylulose kinase from bifidobacterium adolescentis
    25% identity, 74% coverage of query (50.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory