Searching for up to 100 curated homologs for BWI76_RS27570 FitnessBrowser__Koxy:BWI76_RS27570 (363 a.a.)
Found high-coverage hits (≥70%) to 24 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 4.A.2.1.9 / Q1R4T1 Putative PTS enzyme-II fructose, component of The FrzABC PTS putative transporter (promotes bacterial fitness under stress conditions and promotes fimbrial (fim) gene expression indirectly (Rouquet et al., 2009). Might transport D-tagatose, D-psicose and/or D-sorbose, or a disaccharide of these (Rouquet et al. 2009); involved in environmental sensing, host adaptation and virulence from Escherichia coli (strain UTI89 / UPEC) (see paper)
95% identity, 100% coverage of query (691 bits)
PTFBC_XANCP / P23355 PTS system fructose-specific EIIB'BC component; EIIB'BC-Fru; EC 2.7.1.202 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
46% identity, 93% coverage of query (265 bits)
AZOBR_RS32335 fructose-specific PTS system (fructose 1-phosphate forming), EII-B'BC components (FruA) from Azospirillum brasilense Sp245
44% identity, 90% coverage of query (262 bits)
FruA / b2167 fructose-specific PTS multiphosphoryl transfer protein FruA from Escherichia coli K-12 substr. MG1655 (see 4 papers)
fruA / P20966 fructose-specific PTS multiphosphoryl transfer protein FruA from Escherichia coli (strain K12) (see 2 papers)
PTFBC_ECOLI / P20966 PTS system fructose-specific EIIB'BC component; EIIB'BC-Fru; EC 2.7.1.202 from Escherichia coli (strain K12) (see 3 papers)
TC 4.A.2.1.1 / P20966 PTFB aka FRUA aka PTSF aka B2167, component of Fructose porter (FruAB) (fructose-1-P forming) from Escherichia coli (see 6 papers)
42% identity, 89% coverage of query (258 bits)
PTFBC_VIBCH / Q9KM72 PTS system fructose-specific EIIB'BC component; EC 2.7.1.202 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
40% identity, 94% coverage of query (256 bits)
TC 4.A.2.1.26 / Q5V5X5 Sugar phosphotransferase system IIC component, component of Fructose-specific Enzyme I-HPr-Enzyme IIABC complex, all encoded within a single operon with genes in the order: ptsC (IIC), ptsA (IIA), ptsH (HPr), ptsI (Enzyme I) and ptsB (IIB) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
37% identity, 95% coverage of query (246 bits)
TC 4.A.2.1.4 / P71012 The fructose porter, FruA (fructose-1-P forming IIABC) (Delobbe et al. 1975) FruA is 39% identical to 4.A.2.1.1). fructose can be metabolized to Fru-1-P via this system as well as Fru-6-P by another PTS system from Bacillus subtilis (see paper)
42% identity, 90% coverage of query (241 bits)
TC 4.A.2.1.17 / Q9HY57 Phosphotransferase system transporter fructose-specific IIBC component, FruA, component of Fructose-specific PTS permease, FruIIBC/FruI-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
42% identity, 90% coverage of query (239 bits)
TC 4.A.2.1.14 / D2RXA8 PTS system, fructose subfamily, IIC subunit, component of Fructose Enzyme II complex (IIAFru - IIBFru - IICFru) (based on homology) from Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (see paper)
39% identity, 91% coverage of query (235 bits)
PTFC_HALVD / D4GYE5 PTS system fructose-specific EIIC component; EIIC-Fru; Fructose permease IIC from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
TC 4.A.2.1.15 / D4GYE5 Phosphotransferase system, EIIC, putative, component of Fructose-specific PTS, PtfABC from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see paper)
37% identity, 95% coverage of query (212 bits)
Q8DWE7 protein-Npi-phosphohistidine-D-fructose phosphotransferase (subunit 2/2) (EC 2.7.1.202) from Streptococcus mutans serotype c (see paper)
TC 4.A.2.1.8 / Q8DWE7 Putative PTS system, fructose-specific IIBC component aka FruC, component of The constitutive fructose porter FruC/FruD from Streptococcus mutans (see paper)
35% identity, 91% coverage of query (210 bits)
TC 4.A.2.1.22 / Q3JZE4 PTS system, fructose-specific, IIC component, component of D-allose/D-ribose transporting Enzyme II complex (Fru2; IIA/IIB/IIC) (Patron et al. 2017). This system is similar to Frz of E. coli (TC#4.A.2.1.9) which is involved in environmental sensing, host adaptation and virulence from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
36% identity, 96% coverage of query (207 bits)
TC 4.A.2.1.18 / Q9RZP7 Fructose PTS Enzyme IIBC, FruA from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
43% identity, 88% coverage of query (206 bits)
PTN3B_BACSU / O31645 PTS system mannose-specific EIIBCA component; EIIBCA-Man; EII-Man; EC 2.7.1.191 from Bacillus subtilis (strain 168) (see 2 papers)
O31645 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Bacillus subtilis (see paper)
TC 4.A.2.1.6 / O31645 The mannose porter (ManP) (37% identical to 4.A.2.1.1). It is encoded in an operon with 3 genes: from Bacillus subtilis (see 5 papers)
39% identity, 90% coverage of query (199 bits)
TC 4.A.2.1.19 / M7PF02 PTS family enzyme IIB'BC, fructose-specific, component of The tagatose-specific PTS transporter/kinase, TagIIA-TPr/TagIIB'BC (tagatose-1-P forming) from Klebsiella pneumoniae ATCC BAA-2146
34% identity, 91% coverage of query (199 bits)
TC 4.A.2.1.7 / Q1LZ59 The fructose inducible fructose/xylitol porter, FruI from Streptococcus mutans UA159 (see paper)
34% identity, 89% coverage of query (199 bits)
MngA 2-O-α-mannosyl-D-glycerate specific PTS enzyme II (EC 2.7.1.195) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
MngA / P54745 2-O-α-mannosyl-D-glycerate specific PTS enzyme II (EC 2.7.1.195) from Escherichia coli (strain K12) (see 5 papers)
MNGA_ECOLI / P54745 PTS system 2-O-alpha-mannosyl-D-glycerate-specific EIIABC component; 2-O-alpha-mannosyl-D-glycerate-specific phosphotransferase enzyme MngA; Protein-Npi-phosphohistidine--2-O-alpha-mannosyl-D-glycerate phosphotransferase; EC 2.7.1.195 from Escherichia coli (strain K12) (see 2 papers)
P54745 protein-Npi-phosphohistidine-2-O-alpha-mannosyl-D-glycerate phosphotransferase (EC 2.7.1.195) from Escherichia coli (see paper)
TC 4.A.2.1.3 / P54745 The 2-O-α-mannosyl D-glycerate porter (2-O-α-mannosyl D-glycerate-6-P forming), MngA (HrsA) from Escherichia coli (see 5 papers)
38% identity, 82% coverage of query (198 bits)
TC 4.A.2.1.13 / Q0S1N2 The fructose-specific PTS Enzyme IIABC FruA from Rhodococcus sp. (strain RHA1) (see paper)
38% identity, 82% coverage of query (194 bits)
TC 4.A.2.1.20 / Q3K0G6 Chromosomal fructose Enzyme IIABC (Fru1) of 654 aas; in an operon with fructose-1-P kinase from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
33% identity, 92% coverage of query (191 bits)
tagL / A0A415J7H7 tagatose-specific PTS enzyme IIBC component from Bacillus licheniformis (see 2 papers)
TC 4.A.2.1.23 / T5HN74 PTS fructose transporter subunit IIC, component of The tagatose-1-P-forming tagatose phosphorylating Enzyme IIA/IIBC, TagM/L (Van der Heiden et al. 2015). The product is phosphorylated by tagatose-1-P kinase (TagK), and then cleaved by tagatose-1,6-bisphosphate aldolase (GatY) from Bacillus licheniformis CG-B52
34% identity, 93% coverage of query (189 bits)
FrwC / b3949 putative PTS enzyme IIC component FrwC from Escherichia coli K-12 substr. MG1655 (see 2 papers)
FrwC / P32672 putative PTS enzyme IIC component FrwC from Escherichia coli (strain K12) (see paper)
PTFC2_ECOLI / P32672 Fructose-like permease IIC component 2; PTS system fructose-like EIIC component 2 from Escherichia coli (strain K12) (see paper)
37% identity, 84% coverage of query (173 bits)
Build an alignment for BWI76_RS27570 and 21 homologs with ≥ 30% identity
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FrvB / b3899 putative PTS enzyme IIBC component FrvB from Escherichia coli K-12 substr. MG1655 (see 4 papers)
frvB / P32154 putative PTS enzyme IIBC component FrvB from Escherichia coli (strain K12) (see 3 papers)
TC 4.A.2.1.25 / P32154 Fructose-like PTS system EIIBC component, component of Fructose-like PTS Enzyme II complex, FrvA (IIA of 148 aas) - FrvB (IIBC of 483 aas and 9 predicted TMSs) from Escherichia coli (strain K12)
29% identity, 93% coverage of query (150 bits)
TC 4.A.2.1.16 / Q9RMF5 Fructose-specific Enzyme IIABC from Spiroplasma citri
26% identity, 92% coverage of query (140 bits)
YpdG / b2386 putative PTS enzyme IIC component FryC from Escherichia coli K-12 substr. MG1655 (see 3 papers)
23% identity, 91% coverage of query (93.2 bits)
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Lawrence Berkeley National Laboratory