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Searching for up to 100 curated homologs for BWI76_RS27590 FitnessBrowser__Koxy:BWI76_RS27590 (772 a.a.)

Found high-coverage hits (≥70%) to 59 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YicI / b3656 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
yicI / P31434 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Escherichia coli (strain K12) (see 9 papers)
XYLS_ECOLI / P31434 Alpha-xylosidase; EC 3.2.1.177 from Escherichia coli (strain K12) (see 3 papers)
P31434 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from Escherichia coli (see 3 papers)
AAC76680.1 α-xylosidase (YicI;EcYicI;b3656) (EC 3.2.1.177) (see protein)
BAE77637.1 α-xylosidase (YicI) (EC 3.2.1.177) (see protein)
yicI / RF|NP_418113 alpha-xylosidase; EC 3.2.1.- from Escherichia coli K12 (see 7 papers)
    86% identity, 100% coverage of query (1428 bits)

2f2hA / P31434 Structure of the yici thiosugar michaelis complex (see paper)
    86% identity, 100% coverage of query (1427 bits)

1xskA Structure of a family 31 alpha glycosidase glycosyl-enzyme intermediate
    86% identity, 100% coverage of query (1427 bits)

AGDD_EMENI / Q5AW25 Alpha-xylosidase; EC 3.2.1.177 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 2 papers)
EAA62085.1 α-xylosidase (AgdD;AN7505) (EC 3.2.1.177) (see protein)
agdD alpha-xylosidase from Emericella nidulans (see paper)
    48% identity, 88% coverage of query (702 bits)

XYLQ_LACPE / P96793 Alpha-xylosidase XylQ; EC 3.2.1.177 from Lactiplantibacillus pentosus (Lactobacillus pentosus) (see paper)
AAC62251.1 α-xylosidase (XylQ) (EC 3.2.1.177) (see protein)
    47% identity, 94% coverage of query (690 bits)

Build an alignment

Build an alignment for BWI76_RS27590 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

BAQ19546.1 α-glucosidase (AG31A;BspAG31A) (EC 3.2.1.20) (see protein)
    28% identity, 77% coverage of query (262 bits)

Q9F234 alpha-glucosidase (EC 3.2.1.20) from Bacillus thermoamyloliquefaciens (see paper)
BAA76396.1 α-glucosidase II / oligo-α-1,6-glucosidase (BthG II) (EC 3.2.1.10|3.2.1.20) (see protein)
    26% identity, 84% coverage of query (251 bits)

Q745T6 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB27 (see paper)
    29% identity, 74% coverage of query (241 bits)

ACO57638.1 α-1,3-glucosidase (LjAg31) (partial) (EC 3.2.1.84) (see protein)
    26% identity, 81% coverage of query (240 bits)

6jr7A / A5FBI1 Flavobacterium johnsoniae gh31 dextranase, fjdex31a, complexed with glucose (see paper)
    27% identity, 82% coverage of query (239 bits)

A5FBI1 dextranase (EC 3.2.1.11) from Flavobacterium johnsoniae (see paper)
ABQ07434.1 dextranase/6-α-glucosyltransferase (Fjoh_4430) (EC 3.2.1.11|2.4.1.-) (see protein)
    27% identity, 82% coverage of query (239 bits)

5hxmA / Q8Y4J2 Cycloalternan-forming enzyme from listeria monocytogenes in complex with panose (see paper)
    27% identity, 75% coverage of query (238 bits)

4kwuA 1.9 angstrom resolution crystal structure of uncharacterized protein lmo2446 from listeria monocytogenes egd-e in complex with alpha-d- glucose, beta-d-glucose, magnesium and calcium
    27% identity, 75% coverage of query (238 bits)

BAD34979.1 3-α-isomaltosyltransferase (CtsY;IMT) (EC 2.4.1.-) (see protein)
    28% identity, 75% coverage of query (233 bits)

BAC54957.1 3-α-isomaltosyltransferase (CtsY;IMT) (EC 2.4.1.-) (see protein)
    26% identity, 86% coverage of query (224 bits)

ctsY / Q8RQV0 isomaltosyltransferase (EC 2.4.1.387) from Sporosarcina globispora (see 3 papers)
BAB88403.1 3-α-isomaltosyltransferase (CtsY) (EC 2.4.1.-) (see protein)
    27% identity, 76% coverage of query (219 bits)

Q8RDL1 alpha-glucosidase (EC 3.2.1.20) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
AAM23323.1 α-glucosidase (GluA;TTE0006) (EC 3.2.1.20) (see protein)
    26% identity, 77% coverage of query (214 bits)

ABR26230.1 α-glucosidase (EC 3.2.1.20) (see protein)
    26% identity, 75% coverage of query (210 bits)

Q9HLD0 alpha-glucosidase (EC 3.2.1.20) from Thermoplasma acidophilum (see paper)
CAC11443.1 α-glucosidase (AglA;Ta0298) (EC 3.2.1.20) (see protein)
    23% identity, 89% coverage of query (201 bits)

OL4AG_CELJU / B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase; Alpha-glucosidase 31B; CJAgd31B; EC 2.4.1.161 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
ACE84782.1 oligosaccharide α-1,4-transglucosylase 31B (CjAgd31B;CJA_3248) (Agd31B) (EC 2.4.1.161) (see protein)
    24% identity, 73% coverage of query (187 bits)

4ba0A / B3PEE6 Crystal structure of agd31b, alpha-transglucosylase, complexed with 5f-alpha-glcf (see paper)
    25% identity, 73% coverage of query (186 bits)

7p4dAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    24% identity, 73% coverage of query (184 bits)

7p4cAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    24% identity, 73% coverage of query (184 bits)

5npeA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with beta cyclophellitol aziridine probe ky358
    24% identity, 73% coverage of query (184 bits)

5npbA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol cyclosulfate probe me647
    24% identity, 73% coverage of query (184 bits)

4b9zA Crystal structure of agd31b, alpha-transglucosylase, complexed with acarbose
    24% identity, 73% coverage of query (184 bits)

4b9yA Crystal structure of apo agd31b, alpha-transglucosylase in glycoside hydrolase family 31
    24% identity, 73% coverage of query (184 bits)

5i24A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf021
    25% identity, 73% coverage of query (184 bits)

5i23A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf022
    25% identity, 73% coverage of query (184 bits)

5npdA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol aziridine probe cf021
    24% identity, 73% coverage of query (182 bits)

5npcA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with unreacted alpha cyclophellitol cyclosulfate probe me647
    24% identity, 73% coverage of query (182 bits)

4xppA Crystal structure of pedobacter saltans gh31 alpha-galactosidase complexed with d-galactose
    25% identity, 73% coverage of query (169 bits)

Q6L2X4 alpha-glucosidase (EC 3.2.1.20) from Picrophilus torridus (see paper)
AAT42677.1 α-glucosidase (AglA;PTO0092) (EC 3.2.1.20) (see protein)
    22% identity, 78% coverage of query (167 bits)

4xpqA / A0A0F7R6D6 Crystal structure of pedobacter saltans gh31 alpha-galactosidase complexed with l-fucose (see paper)
    25% identity, 73% coverage of query (166 bits)

BAR72452.1 α-galactosidase (PsGal31A) (Gal31A) (EC 3.2.1.22) (see protein)
    25% identity, 73% coverage of query (166 bits)

4xpsA Crystal structure of the mutant d365a of pedobacter saltans gh31 alpha-galactosidase complexed with p-nitrophenyl-alpha- galactopyranoside
    25% identity, 73% coverage of query (166 bits)

smoI / A9CEZ0 sulfoquinovosidase (EC 3.2.1.199) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see 3 papers)
SQASE_AGRFC / A9CEZ0 Sulfoquinovosidase; SQase; AtSQase; SQ monooxygenase cluster protein I; EC 3.2.1.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
    24% identity, 75% coverage of query (153 bits)

EDO10789.1 α-xylosidase (BoGH31;BACOVA_03422) (EC 3.2.1.177) (see protein)
    22% identity, 74% coverage of query (148 bits)

AAX04434.1 α-glucosidase (EC 3.2.1.20) (see protein)
    24% identity, 74% coverage of query (146 bits)

7ofxB / A9CEZ0 Crystal structure of a gh31 family sulfoquinovosidase mutant d455n from agrobacterium tumefaciens in complex with sulfoquinovosyl glycerol (sqgro) (see paper)
    23% identity, 75% coverage of query (139 bits)

5ohsA A gh31 family sulfoquinovosidase mutant d455n in complex with pnpsq
    23% identity, 75% coverage of query (139 bits)

CAI26256.1 glucosidase II, α-subunit (GII) (EC 3.2.1.20) (see protein)
glcaseIIa / CAI26256.1 glucosidase II, alpha subunit precursor from Trypanosoma brucei brucei (see paper)
    24% identity, 73% coverage of query (138 bits)

3l4uA / O43451 Crystal complex of n-terminal human maltase-glucoamylase with de-o- sulfonated kotalanol (see paper)
    23% identity, 78% coverage of query (134 bits)

AAC39568.2 maltase-glucoamylase (MgaM;Mga;MGAML) (EC 3.2.1.20) (see protein)
    23% identity, 78% coverage of query (134 bits)

3cttA Crystal complex of n-terminal human maltase-glucoamylase with casuarine
    23% identity, 78% coverage of query (134 bits)

3l4zA Crystal complex of n-terminal human maltase-glucoamylase with salacinol
    23% identity, 78% coverage of query (134 bits)

3l4yA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8ii
    23% identity, 78% coverage of query (134 bits)

3l4xA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8
    23% identity, 78% coverage of query (134 bits)

3l4wA Crystal complex of n-terminal human maltase-glucoamylase with miglitol
    23% identity, 78% coverage of query (134 bits)

3l4vA Crystal complex of n-terminal human maltase-glucoamylase with kotalanol
    23% identity, 78% coverage of query (134 bits)

2qmjA Crystral structure of the n-terminal subunit of human maltase- glucoamylase in complex with acarbose
    23% identity, 78% coverage of query (134 bits)

MGA_HUMAN / O43451 Maltase-glucoamylase; Alpha-1,4-glucosidase; EC 3.2.1.20 from Homo sapiens (Human) (see 8 papers)
    23% identity, 78% coverage of query (133 bits)

5kzwA / P10253 Crystal structure of human gaa
    22% identity, 72% coverage of query (133 bits)

5nn6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-hydroxyethyl-1-deoxynojirimycin
    22% identity, 72% coverage of query (132 bits)

5nn8A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with acarbose
    22% identity, 72% coverage of query (132 bits)

5nn5A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with 1-deoxynojirimycin
    22% identity, 72% coverage of query (131 bits)

7p32AAA Lysosomal alpha-glucosidase
    22% identity, 72% coverage of query (131 bits)

5nn4A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-acetyl-cysteine
    22% identity, 72% coverage of query (131 bits)

AAA31459.1 sucrase-isomaltase (SI) (EC 3.2.1.10|3.2.1.20|3.2.1.48) (see protein)
    22% identity, 75% coverage of query (125 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory