Sites on a Tree

 

Searching for up to 100 curated homologs for CA265_RS00760 FitnessBrowser__Pedo557:CA265_RS00760 (254 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DDGLD_PSEA6 / Q15SS0 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2,5-diketo-3-deoxy-L-galactonate 5-reductase; EC 1.1.1.127 from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
    72% identity, 100% coverage of query (375 bits)

kduD / Q05528 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127) from Dickeya dadantii (strain 3937) (see 3 papers)
KDUD_DICD3 / Q05528 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; EC 1.1.1.127 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    50% identity, 99% coverage of query (260 bits)

G3XRE5 gluconate 5-dehydrogenase (EC 1.1.1.69) from Aspergillus niger (see paper)
    52% identity, 100% coverage of query (258 bits)

KDUD_BACSU / P50842 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; EC 1.1.1.127 from Bacillus subtilis (strain 168) (see paper)
    54% identity, 100% coverage of query (254 bits)

YgeC / b2842 putative 2-keto-3-deoxy-D-gluconate dehydrogenase (EC 1.1.1.127) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
kduD / P37769 putative 2-keto-3-deoxy-D-gluconate dehydrogenase (EC 1.1.1.127) from Escherichia coli (strain K12) (see 5 papers)
KDUD_ECOLI / P37769 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-deoxy-D-gluconate 3-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; 20-ketosteroid reductase; EC 1.1.1.127; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
    49% identity, 98% coverage of query (248 bits)

4za2D Crystal structure of pectobacterium carotovorum 2-keto-3-deoxy-d- gluconate dehydrogenase complexed with NAD+ (see paper)
    47% identity, 99% coverage of query (243 bits)

3uf0A / C5BY10 Crystal structure of a putative NAD(p) dependent gluconate 5- dehydrogenase from beutenbergia cavernae(efi target efi-502044) with bound NADP (low occupancy)
    49% identity, 98% coverage of query (228 bits)

4hp8B / A9CEQ9 Crystal structure of a putative 2-deoxy-d-gluconate 3-dehydrogenase from agrobacterium tumefaciens (target efi-506435) with bound NADP
    51% identity, 99% coverage of query (225 bits)

dhuD / Q8E370 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase monomer (EC 1.1.1.127) from Streptococcus agalactiae serotype III (strain NEM316) (see paper)
    42% identity, 99% coverage of query (186 bits)

YjgU / b4266 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
idnO / P0A9P9 5-keto-D-gluconate 5-reductase (EC 1.1.1.69) from Escherichia coli (strain K12) (see 4 papers)
IDNO_ECOLI / P0A9P9 5-keto-D-gluconate 5-reductase; EC 1.1.1.69 from Escherichia coli (strain K12) (see paper)
    41% identity, 99% coverage of query (184 bits)

3o03A Quaternary complex structure of gluconate 5-dehydrogenase from streptococcus suis type 2 (see paper)
    43% identity, 98% coverage of query (180 bits)

PLH6_FORAG / T2KLZ8 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; 2-deoxy-D-gluconate 3-dehydrogenase; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase; P6_dehydrogenase; Polysaccharide utilization locus H protein P6; PUL H protein P6; EC 1.1.1.127 from Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) (see paper)
    39% identity, 98% coverage of query (177 bits)

YgcW / b2774 putative deoxygluconate dehydrogenase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    41% identity, 99% coverage of query (176 bits)

gno / P50199 D-gluconate 5-dehydrogenase monomer from Gluconobacter oxydans (strain 621H) (see paper)
GNO_GLUOX / P50199 Gluconate 5-dehydrogenase; D-gluconate 5-dehydrogenase (NADP); Gluconate:NADP 5-oxidoreductase; GNO; EC 1.1.1.- from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    39% identity, 98% coverage of query (169 bits)

uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    39% identity, 99% coverage of query (168 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    38% identity, 97% coverage of query (166 bits)

1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
    39% identity, 98% coverage of query (165 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    38% identity, 98% coverage of query (159 bits)

Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
    35% identity, 95% coverage of query (158 bits)

5u9pB / B4EEX4 Crystal structure of a gluconate 5-dehydrogenase from burkholderia cenocepacia j2315 in complex with NADP and tartrate
    40% identity, 97% coverage of query (157 bits)

3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
    38% identity, 98% coverage of query (156 bits)

GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
    37% identity, 97% coverage of query (155 bits)

tpdE / M1WXK8 aminoalcohol dehydrogenase from Rhodococcus sp. TMP1 (see paper)
tpdE / CCN27364.1 aminoalcohol dehydrogenase from Rhodococcus sp. TMP1 (see paper)
    36% identity, 99% coverage of query (151 bits)

FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
    36% identity, 97% coverage of query (151 bits)

1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
    37% identity, 97% coverage of query (151 bits)

AT1G24360 / P33207 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC 1.1.1.100) from Arabidopsis thaliana (see paper)
    37% identity, 94% coverage of query (149 bits)

6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
    36% identity, 97% coverage of query (149 bits)

1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
    36% identity, 97% coverage of query (149 bits)

4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
    37% identity, 98% coverage of query (148 bits)

1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
    37% identity, 94% coverage of query (147 bits)

GATDH_CERSP / C0KTJ6 Galactitol 2-dehydrogenase (L-tagatose-forming); Galactitol dehydrogenase; GDH; GatDH; Galactitol:NAD(+) 5-oxidoreductase; EC 1.1.1.406 from Cereibacter sphaeroides (Rhodobacter sphaeroides) (see 4 papers)
C0KTJ6 galactitol 2-dehydrogenase (L-tagatose-forming) (EC 1.1.1.406) from Cereibacter sphaeroides (see 4 papers)
3lqfA / C0KTJ6 Crystal structure of the short-chain dehydrogenase galactitol- dehydrogenase (gatdh) of rhodobacter sphaeroides in complex with NAD and erythritol (see paper)
    40% identity, 98% coverage of query (145 bits)

FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    35% identity, 97% coverage of query (145 bits)

2wsbA Crystal structure of the short-chain dehydrogenase galactitol-dehydrogenase (gatdh) of rhodobacter sphaeroides in complex with NAD
    40% identity, 98% coverage of query (145 bits)

2wdzA Crystal structure of the short chain dehydrogenase galactitol-dehydrogenase (gatdh) of rhodobacter sphaeroides in complex with NAD+ and 1,2-pentandiol
    40% identity, 98% coverage of query (145 bits)

Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Deinococcus geothermalis (see paper)
    37% identity, 98% coverage of query (144 bits)

FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
    36% identity, 96% coverage of query (142 bits)

7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
    36% identity, 96% coverage of query (139 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    34% identity, 95% coverage of query (139 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    34% identity, 95% coverage of query (139 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    34% identity, 95% coverage of query (139 bits)

FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
    34% identity, 98% coverage of query (138 bits)

hpsO / Q46N54 (S)-sulfopropanediol 2-dehydrogenase from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    35% identity, 98% coverage of query (135 bits)

FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    37% identity, 97% coverage of query (135 bits)

3tzcA Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg)(y155f) from vibrio cholerae (see paper)
    37% identity, 98% coverage of query (134 bits)

7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
    36% identity, 98% coverage of query (134 bits)

A0A1H3NGY9 gluconate 5-dehydrogenase (EC 1.1.1.69) from Lentibacter algarum (see paper)
    37% identity, 100% coverage of query (133 bits)

BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
    35% identity, 97% coverage of query (132 bits)

4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
    32% identity, 95% coverage of query (132 bits)

phbB / AAA90983.1 acetoacetyl CoA reductase from Sinorhizobium meliloti (see 2 papers)
    35% identity, 95% coverage of query (130 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    34% identity, 97% coverage of query (130 bits)

3BHD2_EGGLE / C8WGQ3 3beta-hydroxysteroid dehydrogenase 2; 3beta-HSDH 2; 3beta-hydroxycholanate 3-dehydrogenase (NAD(+)) 2; NAD-dependent bile acid 3beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.391 from Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B) (Eubacterium lentum) (see paper)
C8WGQ3 3beta-hydroxycholanate 3-dehydrogenase (NAD+) (EC 1.1.1.391) from Eggerthella lenta (see paper)
    35% identity, 96% coverage of query (130 bits)

fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
    36% identity, 95% coverage of query (128 bits)

Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Synechococcus elongatus PCC 7942 = FACHB-805 (see paper)
    36% identity, 97% coverage of query (127 bits)

5b4tA / D0VWQ0 Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and a substrate d-3- hydroxybutyrate (see paper)
    35% identity, 98% coverage of query (126 bits)

4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
    38% identity, 96% coverage of query (126 bits)

3w8dA Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate
    35% identity, 98% coverage of query (126 bits)

3vdrA Crystal structure of d-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate d-3-hydroxybutyrate and NAD(+)
    35% identity, 98% coverage of query (126 bits)

3vdqA Crystal structure of alcaligenes faecalis d-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate
    35% identity, 98% coverage of query (126 bits)

4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
    36% identity, 97% coverage of query (124 bits)

4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
    33% identity, 96% coverage of query (123 bits)

A0A0M4UR95 L-xylulose reductase (EC 1.1.1.10) from Rhizomucor pusillus (see paper)
    34% identity, 97% coverage of query (123 bits)

Pf6N2E2_1959 D-sorbitol dehydrogenase (EC 1.1.1.14) from Pseudomonas fluorescens FW300-N2E2
    35% identity, 97% coverage of query (123 bits)

NR_NARAP / A0A1C9II22 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus aff. pseudonarcissus MK-2014 (Daffodil) (see paper)
NR_NARPS / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus pseudonarcissus (Daffodil) (see 2 papers)
5ff9B / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and tyramine (see paper)
    33% identity, 97% coverage of query (123 bits)

5fffA Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and piperonal
    33% identity, 97% coverage of query (123 bits)

6pejA / Q92N06 Structure of sorbitol dehydrogenase from sinorhizobium meliloti 1021 bound to sorbitol
    35% identity, 97% coverage of query (122 bits)

7krmC / A0A077GFB1 Putative fabg bound to nadh from acinetobacter baumannii
    35% identity, 97% coverage of query (121 bits)

6j7uA / D6NKF4 Crystal structure of blue fluorescent protein from metagenomic library in complex with NADPH (see paper)
    35% identity, 97% coverage of query (121 bits)

4ag3A Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with NADPH at 1.8a resolution
    34% identity, 97% coverage of query (120 bits)

6wprA Crystal structure of a putative 3-oxoacyl-acp reductase (fabg) with NADP(h) from acinetobacter baumannii
    30% identity, 95% coverage of query (120 bits)

6t62A / V5VHN7 Crystal structure of acinetobacter baumannii fabg in complex with NADPH at 1.8 a resolution (see paper)
    30% identity, 95% coverage of query (120 bits)

DHRS4_HUMAN / Q9BTZ2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; Short-chain dehydrogenase/reductase family member 4; EC 1.1.1.184 from Homo sapiens (Human) (see 7 papers)
Q9BTZ2 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens (see paper)
    33% identity, 98% coverage of query (120 bits)

3o4rA / Q9BTZ2 Crystal structure of human dehydrogenase/reductase (sdr family) member 4 (dhrs4)
    33% identity, 98% coverage of query (120 bits)

5ha5D Crystal structure of an NAD-bound oxidoreductase from brucella ovis
    34% identity, 96% coverage of query (119 bits)

2ekpA / Q53W82 Structure of tt0495 protein from thermus thermophilus (see paper)
    31% identity, 96% coverage of query (119 bits)

4b79A / Q9HWT0 The aeropath project and pseudomonas aeruginosa high-throughput crystallographic studies for assessment of potential targets in early stage drug discovery. (see paper)
    32% identity, 96% coverage of query (119 bits)

5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
    32% identity, 99% coverage of query (119 bits)

4bnzA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-methyl-n-phenylindole- 3-carboxamide at 2.5a resolution
    34% identity, 97% coverage of query (116 bits)

TR2 / P50163 tropinone reductase (EC 1.1.1.236) from Datura stramonium (see paper)
TRN2_DATST / P50163 Tropinone reductase 2; Tropinone reductase II; TR-II; EC 1.1.1.236 from Datura stramonium (Jimsonweed) (Common thornapple) (see paper)
P50163 tropinone reductase II (EC 1.1.1.236) from Datura stramonium (see 3 papers)
    32% identity, 99% coverage of query (116 bits)

4bo4C / O54438 Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2-methoxyphenyl)-3,4- dihydro-2h-quinoline-1-carboxamide at 2.7a resolution (see paper)
    34% identity, 98% coverage of query (116 bits)

7do7A Crystal structure of azotobacter vinelandii l-rhamnose 1- dehydrogenase(NAD and l-rhamnose bound-form)
    33% identity, 96% coverage of query (115 bits)

7b81A / C1DMX5 Crystal structure of azotobacter vinelandii l-rhamnose 1-dehydrogenase (NAD bound-form) (see paper)
    33% identity, 96% coverage of query (115 bits)

4fn4A / Q4J9F2 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius (see paper)
    30% identity, 97% coverage of query (115 bits)

2ae2A / P50163 Tropinone reductase-ii complexed with NADP+ and pseudotropine (see paper)
    32% identity, 98% coverage of query (115 bits)

1ipfA Tropinone reductase-ii complexed with NADPH and tropinone
    32% identity, 98% coverage of query (115 bits)

1ipeA Tropinone reductase-ii complexed with NADPH
    32% identity, 98% coverage of query (115 bits)

2zatA / Q8WNV7 Crystal structure of a mammalian reductase (see paper)
    33% identity, 98% coverage of query (115 bits)

DHRS4_PIG / Q8WNV7 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal carbonyl reductase; PerCR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; EC 1.1.1.184; EC 1.1.1.300 from Sus scrofa (Pig) (see 3 papers)
    33% identity, 98% coverage of query (115 bits)

5vmlA / Q3JRS9 Crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710b with bound NADP
    32% identity, 95% coverage of query (115 bits)

novJ / Q9L9F8 NovJ from Streptomyces niveus (see paper)
NOVJ_STRNV / Q9L9F8 Short-chain reductase protein NovJ; Novobiocin biosynthesis protein J; EC 1.1.1.- from Streptomyces niveus (Streptomyces spheroides) (see paper)
    36% identity, 94% coverage of query (114 bits)

4bnxA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 6-(4-(2-chloroanilino)- 1h-quinazolin-2-ylidene)cyclohexa-2, 4-dien-1-one at 2.3a resolution
    34% identity, 97% coverage of query (114 bits)

4bnyA Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 4-(2-phenylthieno(3,2-d) pyrimidin-4-yl)morpholine at 1.8a resolution
    34% identity, 97% coverage of query (114 bits)

TRN1_COCOF / A7DY56 Tropinone reductase; EC 1.1.1.206; EC 1.1.1.236 from Cochlearia officinalis (Common scurvygrass) (see paper)
A7DY56 tropinone reductase I (EC 1.1.1.206); tropinone reductase II (EC 1.1.1.236) from Cochlearia officinalis (see paper)
    31% identity, 97% coverage of query (113 bits)

6y4dA Crystal structure of a short-chain dehydrogenase/reductase (sdr) from zephyranthes treatiae in complex with NADP+ (see paper)
    32% identity, 97% coverage of query (113 bits)

4bo7A Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2,3-dihydro-1h-inden- 5-yl)tetrazolo(1,5-b)pyridazin-6-amine at 2.6a resolution
    34% identity, 97% coverage of query (113 bits)

3pk0B / A0QQJ6 Crystal structure of short-chain dehydrogenase/reductase sdr from mycobacterium smegmatis (see paper)
    32% identity, 98% coverage of query (113 bits)

5vt6A / Q3JJT1 Crystal structure of acetoacetyl-coa reductase from burkholderia pseudomallei 1710b complexed with NADP
    31% identity, 95% coverage of query (113 bits)

3s55D / B1MLR7 Crystal structure of a putative short-chain dehydrogenase/reductase from mycobacterium abscessus bound to NAD (see paper)
    31% identity, 98% coverage of query (112 bits)

2q2qD / Q9AE70 Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida (see paper)
    34% identity, 98% coverage of query (112 bits)

BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
    33% identity, 95% coverage of query (112 bits)

5mlnB / B8K244 The crystal structure of alcohol dehydrogenase 10 from candida magnoliae
    32% identity, 95% coverage of query (112 bits)

Build an alignment

Build an alignment for CA265_RS00760 and 100 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory