Sites on a Tree

 

Searching for up to 100 curated homologs for CA265_RS02140 FitnessBrowser__Pedo557:CA265_RS02140 (820 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BAQ19546.1 α-glucosidase (AG31A;BspAG31A) (EC 3.2.1.20) (see protein)
    38% identity, 93% coverage of query (579 bits)

Q8RDL1 alpha-glucosidase (EC 3.2.1.20) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
AAM23323.1 α-glucosidase (GluA;TTE0006) (EC 3.2.1.20) (see protein)
    43% identity, 83% coverage of query (574 bits)

Q9F234 alpha-glucosidase (EC 3.2.1.20) from Bacillus thermoamyloliquefaciens (see paper)
BAA76396.1 α-glucosidase II / oligo-α-1,6-glucosidase (BthG II) (EC 3.2.1.10|3.2.1.20) (see protein)
    38% identity, 92% coverage of query (569 bits)

ABR26230.1 α-glucosidase (EC 3.2.1.20) (see protein)
    42% identity, 83% coverage of query (566 bits)

ACO57638.1 α-1,3-glucosidase (LjAg31) (partial) (EC 3.2.1.84) (see protein)
    39% identity, 87% coverage of query (527 bits)

A5FBI1 dextranase (EC 3.2.1.11) from Flavobacterium johnsoniae (see paper)
ABQ07434.1 dextranase/6-α-glucosyltransferase (Fjoh_4430) (EC 3.2.1.11|2.4.1.-) (see protein)
    37% identity, 89% coverage of query (476 bits)

6jr7A / A5FBI1 Flavobacterium johnsoniae gh31 dextranase, fjdex31a, complexed with glucose (see paper)
    37% identity, 89% coverage of query (476 bits)

AAO78405.1 α-glucosidase (BT3299;BT_3299) (EC 3.2.1.20) (see protein)
    37% identity, 76% coverage of query (438 bits)

5hjrA Murine endoplasmic reticulum alpha-glucosidase ii with bound covalent intermediate
    35% identity, 73% coverage of query (395 bits)

5hjoA Murine endoplasmic reticulum alpha-glucosidase ii with bound substrate analogue
    35% identity, 73% coverage of query (395 bits)

5iefA / Q8BHN3 Murine endoplasmic reticulum alpha-glucosidase ii with n-butyl-1- deoxynojirimycin (see paper)
    35% identity, 73% coverage of query (393 bits)

7kb6A Co-crystal structure of alpha glucosidase with compound 7
    35% identity, 73% coverage of query (393 bits)

7k9tA Co-crystal structure of alpha glucosidase with compound 5
    35% identity, 73% coverage of query (393 bits)

7k9qA Co-crystal structure of alpha glucosidase with compound 4
    35% identity, 73% coverage of query (393 bits)

7k9nA Co-crystal structure of alpha glucosidase with compound 2
    35% identity, 73% coverage of query (393 bits)

5ieeA Murine endoplasmic reticulum alpha-glucosidase ii with 1- deoxynojirimycin
    35% identity, 73% coverage of query (393 bits)

5iedA Murine endoplasmic reticulum alpha-glucosidase ii with castanospermine
    35% identity, 73% coverage of query (393 bits)

5h9oA Complex of murine endoplasmic reticulum alpha-glucosidase ii with d- glucose
    35% identity, 73% coverage of query (393 bits)

7kryA Co-crystal structure of alpha glucosidase with compound 11
    35% identity, 73% coverage of query (393 bits)

7kb8A Co-crystal structure of alpha glucosidase with compound 8
    35% identity, 73% coverage of query (393 bits)

7kadA Co-crystal structure of alpha glucosidase with compound 6
    35% identity, 73% coverage of query (393 bits)

7k9oA Co-crystal structure of alpha glucosidase with compound 3
    35% identity, 73% coverage of query (393 bits)

7jtyA Co-crystal structure of alpha glucosidase with compound 1
    35% identity, 73% coverage of query (393 bits)

AAC53182.1 α-glucosidase II (?-GluII;AB;GanAB;GANAB;G2an;Kiaa0088 ) (EC 3.2.1.20|3.2.1.84) (see protein)
    35% identity, 73% coverage of query (390 bits)

GANAB_MOUSE / Q8BHN3 Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha; EC 3.2.1.207 from Mus musculus (Mouse) (see 4 papers)
    35% identity, 73% coverage of query (390 bits)

AAF66685.1 α-glucosidase II (GanAB;G2AN;KIAA0088 ) (EC 3.2.1.20|3.2.1.84) (see protein)
    34% identity, 71% coverage of query (388 bits)

GANAB / Q14697 mannosyl-oligosaccharide α-1,3-glucosidase α subunit (EC 3.2.1.207) from Homo sapiens (see 19 papers)
GANAB_HUMAN / Q14697 Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha; EC 3.2.1.207 from Homo sapiens (Human) (see 6 papers)
Q14697 mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Homo sapiens (see 2 papers)
    34% identity, 71% coverage of query (387 bits)

GANAB_PIG / P79403 Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha; EC 3.2.1.207 from Sus scrofa (Pig) (see paper)
AAB49757.1 α-glucosidase II (EC 3.2.1.20|3.2.1.84) (see protein)
    34% identity, 71% coverage of query (382 bits)

5iegA Murine endoplasmic reticulum alpha-glucosidase ii with n-9'- methoxynonyl-1-deoxynojirimycin
    35% identity, 73% coverage of query (379 bits)

GANC_HUMAN / Q8TET4 Neutral alpha-glucosidase C; EC 3.2.1.20 from Homo sapiens (Human) (see paper)
    33% identity, 80% coverage of query (377 bits)

AAB71267.2 α-glucosidase (Aagr-4;F52D1.1) (EC 3.2.1.20) (see protein)
    34% identity, 71% coverage of query (376 bits)

CAA94764.1 α-glucosidase (Aagr-3;F40F9.6;CELE_F40F9.6) (EC 3.2.1.20) (see protein)
    33% identity, 75% coverage of query (367 bits)

Q9HLD0 alpha-glucosidase (EC 3.2.1.20) from Thermoplasma acidophilum (see paper)
CAC11443.1 α-glucosidase (AglA;Ta0298) (EC 3.2.1.20) (see protein)
    34% identity, 72% coverage of query (364 bits)

GANAB_DICDI / Q94502 Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha; Protein post-translational modification mutant A; EC 3.2.1.207 from Dictyostelium discoideum (Social amoeba) (see paper)
Q94502 mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Dictyostelium discoideum (see paper)
AAB18921.1 α-glucosidase II (ModA;DDB_G0269154) (EC 3.2.1.84) (see protein)
    33% identity, 74% coverage of query (353 bits)

CAG82805.1 α-glucosidase II α-subunit (GII;YALI0B06600g) (EC 3.2.1.84) (see protein)
    32% identity, 81% coverage of query (352 bits)

CAI26256.1 glucosidase II, α-subunit (GII) (EC 3.2.1.20) (see protein)
glcaseIIa / CAI26256.1 glucosidase II, alpha subunit precursor from Trypanosoma brucei brucei (see paper)
    31% identity, 88% coverage of query (341 bits)

L8B8V1 mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Spodoptera frugiperda (see paper)
BAM78680.1 α-glucosidase II α-subunit (SfGII?) (EC 3.2.1.20) (see protein)
    32% identity, 71% coverage of query (339 bits)

L8B8U1 mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Bombyx mori (see paper)
BAM78681.1 α-glucosidase II α-subunit (BmGII?) (EC 3.2.1.20) (see protein)
    33% identity, 71% coverage of query (337 bits)

G0SG42 mannosyl-oligosaccharide alpha-1,3-glucosidase (subunit 2/2) (EC 3.2.1.207) from Chaetomium thermophilum (see 2 papers)
    33% identity, 74% coverage of query (336 bits)

5dkyA / G0SG42 Crystal structure of glucosidase ii alpha subunit (dnj-bound from) (see paper)
    32% identity, 77% coverage of query (335 bits)

5dkzA Crystal structure of glucosidase ii alpha subunit (alpha3-glc2-bound from)
    32% identity, 77% coverage of query (333 bits)

5dl0A Crystal structure of glucosidase ii alpha subunit (glc1man2-bound from)
    32% identity, 77% coverage of query (333 bits)

ACF60497.1 α-glucosidase II α-subunit P2 (Gls2A) (EC 3.2.1.84) (see protein)
    31% identity, 71% coverage of query (324 bits)

H9TU28 mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Sporothrix schenckii (see paper)
AFG25509.1 α-glucosidase II (Rot2;SsROT2) (EC 3.2.1.20|3.2.1.84) (see protein)
    33% identity, 71% coverage of query (324 bits)

BAE61578.1 α-1,3-glucosidase II α-subunit (AoGls2a;G-II;AO090102000559) (EC 3.2.1.84) (see protein)
    32% identity, 74% coverage of query (320 bits)

Build an alignment

Build an alignment for CA265_RS02140 and 45 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

5nn8A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with acarbose
    29% identity, 86% coverage of query (315 bits)

5nn5A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with 1-deoxynojirimycin
    30% identity, 78% coverage of query (315 bits)

8cb1A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-pnt-dnm 15
    31% identity, 78% coverage of query (315 bits)

5kzwA / P10253 Crystal structure of human gaa
    29% identity, 86% coverage of query (314 bits)

5nn6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-hydroxyethyl-1-deoxynojirimycin
    30% identity, 78% coverage of query (314 bits)

7p32AAA Lysosomal alpha-glucosidase
    30% identity, 78% coverage of query (314 bits)

5nn4A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in complex with n-acetyl-cysteine
    30% identity, 78% coverage of query (314 bits)

7p2zAaA Lysosomal alpha-glucosidase
    30% identity, 78% coverage of query (313 bits)

8cb6A Crystal structure of human lysosomal acid-alpha-glucosidase, gaa, in covalent complex with tamra tagged 1,6-epi-cylcophellitol aziridine activity based probe
    30% identity, 78% coverage of query (313 bits)

P70699 Lysosomal alpha-glucosidase; Acid maltase; EC 3.2.1.20 from Mus musculus (Mouse)
    30% identity, 79% coverage of query (313 bits)

xylS / Q9P999 α-D-xyloside xylohydrolase (EC 3.2.1.177) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 2 papers)
XYLS_SACS2 / Q9P999 Alpha-xylosidase; EC 3.2.1.177 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q9P999 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from Saccharolobus solfataricus (see 2 papers)
CAB99206.1 α-xylosidase (XylS;SS03022) (EC 3.2.1.177) (see protein)
    30% identity, 86% coverage of query (312 bits)

AAH10210.1 α-glucosidase (GAA) (lysosomal) (EC 3.2.1.20) (see protein)
    30% identity, 79% coverage of query (310 bits)

CAA68763.1 α-glucosidase A (GAA) (lysosomal) (EC 3.2.1.20) (see protein)
    30% identity, 78% coverage of query (310 bits)

LYAG_HUMAN / P10253 Lysosomal alpha-glucosidase; Acid maltase; Aglucosidase alfa; EC 3.2.1.20 from Homo sapiens (Human) (see 46 papers)
P10253 alpha-glucosidase (EC 3.2.1.20) from Homo sapiens (see 2 papers)
    30% identity, 78% coverage of query (310 bits)

BAA25890.2 acid α-glucosidase (Gaa2;GAAII) (EC 3.2.1.20) (see protein)
    29% identity, 79% coverage of query (309 bits)

LYAG_BOVIN / Q9MYM4 Lysosomal alpha-glucosidase; Acid maltase; EC 3.2.1.20 from Bos taurus (Bovine) (see paper)
AAF81637.1 acidic α-glucosidase (EC 3.2.1.20) (see protein)
    29% identity, 80% coverage of query (307 bits)

CAF05793.1 α-glucosidase II (Gas1) (EC 3.2.1.20) (see protein)
gas1 / CAF05793.1 alpha-glucosidase II precursor from Ustilago maydis (see paper)
    29% identity, 70% coverage of query (300 bits)

BAN67474.1 α-glucosidase (HdAgl1;HdAgl) (EC 3.2.1.20) (see protein)
    30% identity, 77% coverage of query (300 bits)

BAD45913.1 α-glucosidase (Ong1;OngX-H1;Os06g0676700) (EC 3.2.1.20) (see protein)
    31% identity, 76% coverage of query (294 bits)

BAD45910.1 α-glucosidase (Ong2;Ong-2;Ong3;OngX-H3;Os06g0675700) (EC 3.2.1.20) (see protein)
    31% identity, 76% coverage of query (291 bits)

BAA25884.1 α-glucosidase (Gaa1) (EC 3.2.1.20) (see protein)
    28% identity, 78% coverage of query (290 bits)

AGL97 / Q9LLY2 α-glucosidase (EC 3.2.1.20) from Hordeum vulgare (see 3 papers)
Q9LLY2 alpha-glucosidase (EC 3.2.1.20) from Hordeum vulgare (see paper)
AAF76254.1 α-glucosidase (Agl1;Agl97) (EC 3.2.1.20) (see protein)
    30% identity, 78% coverage of query (287 bits)

OL4AG_CELJU / B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase; Alpha-glucosidase 31B; CJAgd31B; EC 2.4.1.161 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
ACE84782.1 oligosaccharide α-1,4-transglucosylase 31B (CjAgd31B;CJA_3248) (Agd31B) (EC 2.4.1.161) (see protein)
    26% identity, 86% coverage of query (275 bits)

AAB02985.1 α-glucosidase (EC 3.2.1.20) (see protein)
    28% identity, 83% coverage of query (275 bits)

XYL1_ARATH / Q9S7Y7 Alpha-xylosidase 1; EC 3.2.1.177 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9S7Y7 alpha-D-xyloside xylohydrolase (EC 3.2.1.177) from Arabidopsis thaliana (see 2 papers)
AAD37363.1 α-glucosidase / α-xylosidase (AtXyl1;AXY3;AtGlu2;Aglu2;Aglu-2;At1g68560) (EC 3.2.1.177|3.2.1.20) (see protein)
    27% identity, 79% coverage of query (275 bits)

BAA99366.1 α-xylosidase (Ong4;OngX-H4;Os01g0130400) (EC 3.2.1.177) (see protein)
    29% identity, 73% coverage of query (275 bits)

ACH86011.1 membrane-bound maltase-glucoamylase (MGAM) (EC 3.2.1.20) (see protein)
    29% identity, 79% coverage of query (273 bits)

7p4dAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    26% identity, 84% coverage of query (272 bits)

7p4cAAA Oligosaccharide 4-alpha-D-glucosyltransferase
    26% identity, 84% coverage of query (272 bits)

5npeA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with beta cyclophellitol aziridine probe ky358
    26% identity, 84% coverage of query (272 bits)

5npbA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol cyclosulfate probe me647
    26% identity, 84% coverage of query (272 bits)

4b9zA Crystal structure of agd31b, alpha-transglucosylase, complexed with acarbose
    26% identity, 84% coverage of query (272 bits)

4b9yA Crystal structure of apo agd31b, alpha-transglucosylase in glycoside hydrolase family 31
    26% identity, 84% coverage of query (272 bits)

5i24A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf021
    26% identity, 84% coverage of query (271 bits)

5i23A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf022
    26% identity, 84% coverage of query (271 bits)

4ba0A / B3PEE6 Crystal structure of agd31b, alpha-transglucosylase, complexed with 5f-alpha-glcf (see paper)
    26% identity, 84% coverage of query (270 bits)

5npdA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol aziridine probe cf021
    26% identity, 84% coverage of query (270 bits)

5npcA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with unreacted alpha cyclophellitol cyclosulfate probe me647
    26% identity, 84% coverage of query (270 bits)

B5THE3 sucrose alpha-glucosidase (EC 3.2.1.48) from Mus musculus (see paper)
    29% identity, 72% coverage of query (269 bits)

D3ZTX4 glucan 1,4-alpha-glucosidase (EC 3.2.1.3) from Rattus norvegicus (see paper)
    29% identity, 73% coverage of query (269 bits)

3l4tA Crystal complex of n-terminal human maltase-glucoamylase with bj2661
    27% identity, 87% coverage of query (266 bits)

ainv / CAE45566.1 invertase from Blastobotrys adeninivorans (see paper)
    28% identity, 78% coverage of query (265 bits)

AAA31459.1 sucrase-isomaltase (SI) (EC 3.2.1.10|3.2.1.20|3.2.1.48) (see protein)
    27% identity, 80% coverage of query (264 bits)

3l4uA / O43451 Crystal complex of n-terminal human maltase-glucoamylase with de-o- sulfonated kotalanol (see paper)
    27% identity, 81% coverage of query (263 bits)

MGA_HUMAN / O43451 Maltase-glucoamylase; Alpha-1,4-glucosidase; EC 3.2.1.20 from Homo sapiens (Human) (see 8 papers)
    27% identity, 81% coverage of query (263 bits)

3l4zA Crystal complex of n-terminal human maltase-glucoamylase with salacinol
    27% identity, 81% coverage of query (263 bits)

3l4yA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8ii
    27% identity, 81% coverage of query (263 bits)

3l4xA Crystal complex of n-terminal human maltase-glucoamylase with nr4-8
    27% identity, 81% coverage of query (263 bits)

3l4wA Crystal complex of n-terminal human maltase-glucoamylase with miglitol
    27% identity, 81% coverage of query (263 bits)

3l4vA Crystal complex of n-terminal human maltase-glucoamylase with kotalanol
    27% identity, 81% coverage of query (263 bits)

2qmjA Crystral structure of the n-terminal subunit of human maltase- glucoamylase in complex with acarbose
    27% identity, 81% coverage of query (263 bits)

3cttA Crystal complex of n-terminal human maltase-glucoamylase with casuarine
    27% identity, 81% coverage of query (263 bits)

AAC39568.2 maltase-glucoamylase (MgaM;Mga;MGAML) (EC 3.2.1.20) (see protein)
    27% identity, 81% coverage of query (262 bits)

3lppB / P14410 Crystal complex of n-terminal sucrase-isomaltase with kotalanol (see paper)
    28% identity, 72% coverage of query (258 bits)

AAT18166.1 sucrase-isomaltase (SI) (EC 3.2.1.10|3.2.1.48) (see protein)
    28% identity, 72% coverage of query (258 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory