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Searching for up to 100 curated homologs for CA265_RS02450 FitnessBrowser__Pedo557:CA265_RS02450 (262 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

FADF_BACSU / P45866 Probable iron-sulfur-binding oxidoreductase FadF; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
    47% identity, 98% coverage of query (254 bits)

ETFQR_SYNWW / Q0AZ32 EtfAB:quinone oxidoreductase; EC 1.18.-.- from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    44% identity, 94% coverage of query (221 bits)

ETFFR_CHRSD / Q1QYW0 Probable membrane-anchored ferredoxin csal_0991; Transmembrane clostridial-type ferredoxin; EC 1.-.-.- from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
    40% identity, 95% coverage of query (166 bits)

AO353_07705 DgcB Dimethylglycine demethylase subunit B (EC 1.5.3.-) from Pseudomonas fluorescens FW300-N2E3
    40% identity, 95% coverage of query (164 bits)

hdrD / P96797 CoB-CoM heterodisulfide reductase catalytic subunit D (EC 1.8.98.1) from Methanosarcina barkeri (strain Fusaro / DSM 804) (see 2 papers)
HDRD_METBF / P96797 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina barkeri (strain Fusaro / DSM 804) (see 2 papers)
TC 3.D.7.1.1 / P96797 HDRD, component of H2:heterodisulfide oxidoreductase, HHO. Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf from Methanosarcina barkeri (see 3 papers)
hdrD / GB|AAZ70545.1 CoB--CoM heterodisulfide reductase iron-sulfur subunit D; EC 1.8.98.1 from Methanosarcina barkeri str. Fusaro (see 3 papers)
    37% identity, 94% coverage of query (149 bits)

HDRD_METTT / A0A0E3NEE1 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1) (see 3 papers)
    33% identity, 94% coverage of query (137 bits)

HDRD_METMA / Q8PVW3 Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D; CoB--CoM heterodisulfide reductase iron-sulfur subunit D; Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D; EC 1.8.98.1 from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) (see paper)
    32% identity, 94% coverage of query (135 bits)

Build an alignment

Build an alignment for CA265_RS02450 and 7 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

TFRB_METTM / D9PUX5 Fumarate reductase (CoM/CoB) subunit B; Thiol:fumarate reductase subunit B; EC 1.3.4.1 from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) (see 2 papers)
    27% identity, 94% coverage of query (77.4 bits)

DVU_3028 / Q726S8 quinone-dependent D-lactate dehydrogenase iron-sulfur subunit (EC 1.1.2.5) from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 3 papers)
    24% identity, 93% coverage of query (74.3 bits)

DVU_3033 / Q726S3 quinone-dependent L-lactate dehydrogenase large subunit (EC 1.1.2.3) from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 4 papers)
    25% identity, 76% coverage of query (70.5 bits)

tmcB / Q72FF0 Tmc electron transfer complex B subunit from Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough) (see 8 papers)
TC 5.B.11.1.1 / Q72FF0 Ferredoxin, 4Fe-4S, putative, component of Pentameric transmembrane electron flow carrier complex, TmcA2BCD from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
    26% identity, 74% coverage of query (65.5 bits)

YkgE / b0306 putative lactate utilization oxidoreductase YkgE from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    23% identity, 89% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory