Searching for up to 100 curated homologs for CA265_RS03475 FitnessBrowser__Pedo557:CA265_RS03475 (473 a.a.)
Found high-coverage hits (≥70%) to 73 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DHE3_DICDI / Q54KB7 Glutamate dehydrogenase, mitochondrial; GDH; EC 1.4.1.3 from Dictyostelium discoideum (Social amoeba) (see 2 papers)
49% identity, 99% coverage of query (470 bits)
DHE3_MOUSE / P26443 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Mus musculus (Mouse) (see 3 papers)
P26443 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Mus musculus (see 2 papers)
52% identity, 98% coverage of query (465 bits)
DHE3_RAT / P10860 Glutamate dehydrogenase 1, mitochondrial; GDH 1; Memory-related gene 2 protein; MRG-2; EC 1.4.1.3 from Rattus norvegicus (Rat) (see paper)
P10860 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Rattus norvegicus (see 3 papers)
52% identity, 98% coverage of query (465 bits)
DHE3_PIG / P42174 Glutamate dehydrogenase 1, mitochondrial; GDH 1; Membrane protein 50; MP50; EC 1.4.1.3 from Sus scrofa (Pig) (see paper)
52% identity, 98% coverage of query (464 bits)
GLUD1 / P00367 Glutamate dehydrogenase 1, mitochondrial (EC 1.4.1.3) from Homo sapiens (see 3 papers)
DHE3_HUMAN / P00367 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Homo sapiens (Human) (see 10 papers)
P00367 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Homo sapiens (see 8 papers)
52% identity, 98% coverage of query (464 bits)
1nqtA Crystal structure of bovine glutamate dehydrogenase-adp complex
52% identity, 98% coverage of query (462 bits)
GLUD2 / P49448 Glutamate dehydrogenase 2, mitochondrial (EC 1.4.1.3) from Homo sapiens (see 3 papers)
DHE4_HUMAN / P49448 Glutamate dehydrogenase 2, mitochondrial; GDH 2; EC 1.4.1.3 from Homo sapiens (Human) (see paper)
P49448 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Homo sapiens (see 6 papers)
51% identity, 98% coverage of query (459 bits)
6dhdA / P00366 Bovine glutamate dehydrogenase complexed with nadh, gtp, glutamate (see paper)
52% identity, 98% coverage of query (458 bits)
3etgA Glutamate dehydrogenase complexed with gw5074
52% identity, 98% coverage of query (458 bits)
3etdA Structure of glutamate dehydrogenase complexed with bithionol
52% identity, 98% coverage of query (458 bits)
6dhlA Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ecg)
52% identity, 98% coverage of query (458 bits)
3eteA Crystal structure of bovine glutamate dehydrogenase complexed with hexachlorophene
52% identity, 98% coverage of query (458 bits)
8ar7A Bovine glutamate dehydrogenase in ternary complex with the allosteric activators adp and leucine
52% identity, 98% coverage of query (458 bits)
6dhmA Bovine glutamate dehydrogenase complexed with zinc
52% identity, 97% coverage of query (457 bits)
DHE3_BOVIN / P00366 Glutamate dehydrogenase 1, mitochondrial; GDH 1; EC 1.4.1.3 from Bos taurus (Bovine) (see 4 papers)
P00366 glutamate dehydrogenase (EC 1.4.1.2); glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Bos taurus (see 3 papers)
51% identity, 98% coverage of query (455 bits)
1hwyA Bovine glutamate dehydrogenase complexed with NAD and 2-oxoglutarate
51% identity, 98% coverage of query (449 bits)
DHE3_DROME / P54385 Glutamate dehydrogenase, mitochondrial; GDH; EC 1.4.1.3 from Drosophila melanogaster (Fruit fly) (see paper)
47% identity, 94% coverage of query (415 bits)
P96110 trimer complex (EC 1.4.1.2) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
P96110 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermotoga maritima (see paper)
gdhA glutamate dehydrogenase; EC 1.4.1.3 from Thermotoga maritima (see 2 papers)
36% identity, 99% coverage of query (290 bits)
DHE3_THELN / Q56304 Glutamate dehydrogenase; GDH; EC 1.4.1.3 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 2 papers)
Q56304 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3); glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Thermococcus litoralis (see 5 papers)
41% identity, 80% coverage of query (285 bits)
DHE4_HALSI / Q5MBG2 NADP-specific glutamate dehydrogenase A1; EC 1.4.1.4 from Halobacterium salinarum (Halobacterium halobium) (see paper)
36% identity, 98% coverage of query (283 bits)
P80319 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Pyrococcus furiosus (see 6 papers)
41% identity, 78% coverage of query (282 bits)
O74024 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermococcus profundus (see 2 papers)
8xd5A / O74024 Cryo-em structure of glutamate dehydrogenase from thermococcus profundus in complex with NADP and glu in the steady stage of reaction
41% identity, 79% coverage of query (280 bits)
8xcoA Cryo-em structure of glutamate dehydrogenase from thermococcus profundus incorporating NADPH in the initial stage of reaction
41% identity, 79% coverage of query (280 bits)
8xcsA Cryo-em structure of glutamate dehydrogenase from thermococcus profundus in complex with NADPH, akg and nh4 in the initial stage of reaction
41% identity, 79% coverage of query (280 bits)
gdhA / GB|AAA64795.1 glutamate dehydrogenase (NAD(P)(+)); EC 1.4.1.3 from Pyrococcus endeavori (see paper)
41% identity, 78% coverage of query (277 bits)
4xgiA / Q2SZ78 Crystal structure of glutamate dehydrogenase from burkholderia thailandensis
43% identity, 77% coverage of query (276 bits)
gdhB / P29051 GdhA (EC 1.4.1.4) from Halobacterium salinarum (see 3 papers)
DHE2_HALSI / P29051 NAD-specific glutamate dehydrogenase A; NAD-GDH A; EC 1.4.1.2 from Halobacterium salinarum (Halobacterium halobium) (see 2 papers)
P29051 glutamate dehydrogenase (EC 1.4.1.2) from Halobacterium salinarum (see 2 papers)
gdhA / GB|AAW19068.1 glutamate dehydrogenase; EC 1.4.1.2 from Halobacterium salinarum (see paper)
34% identity, 96% coverage of query (272 bits)
O59650 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermococcus kodakarensis (see 2 papers)
gdhA glutamate dehydrogenase (NAD(P)(+)); EC 1.4.1.3 from Thermococcus kodakarensis (see paper)
40% identity, 79% coverage of query (267 bits)
DHE2_BACSU / P39633 Catabolic NAD-specific glutamate dehydrogenase RocG; NAD-GDH; Glutamate dehydrogenase; GlutDH; Trigger enzyme RocG; EC 1.4.1.2 from Bacillus subtilis (strain 168) (see 7 papers)
40% identity, 73% coverage of query (264 bits)
GUDB_BACSU / P50735 Cryptic catabolic NAD-specific glutamate dehydrogenase GudB; NAD-GDH; EC 1.4.1.2 from Bacillus subtilis (strain 168) (see 3 papers)
38% identity, 77% coverage of query (258 bits)
Q977X9 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Thermococcus waiotapuensis (see paper)
39% identity, 79% coverage of query (258 bits)
P80053 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Saccharolobus solfataricus (see paper)
36% identity, 80% coverage of query (256 bits)
P80053 Glutamate dehydrogenase 2; GDH-2; EC 1.4.1.3 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
36% identity, 80% coverage of query (256 bits)
3aogA Crystal structure of glutamate dehydrogenase (gdhb) from thermus thermophilus (glu bound form)
40% identity, 81% coverage of query (256 bits)
3aoeB / Q72IC1 Crystal structure of hetero-hexameric glutamate dehydrogenase from thermus thermophilus (leu bound form)
40% identity, 81% coverage of query (255 bits)
Q0E5I0 glutamate dehydrogenase (EC 1.4.1.2) from Halobacillus halophilus (see paper)
37% identity, 78% coverage of query (253 bits)
Q977U6 glutamate dehydrogenase (EC 1.4.1.2) from Haloferax mediterranei (see paper)
33% identity, 94% coverage of query (253 bits)
Q43314 glutamate dehydrogenase (EC 1.4.1.2); glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Arabidopsis thaliana (see 2 papers)
38% identity, 85% coverage of query (250 bits)
6yehA / Q43314 Arabidopsis thaliana glutamate dehydrogenase isoform 1 in apo form (see paper)
38% identity, 85% coverage of query (250 bits)
6yeiF Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD
38% identity, 85% coverage of query (250 bits)
6yeiA Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD
38% identity, 85% coverage of query (250 bits)
DHE1_ORYSJ / Q852M0 Glutamate dehydrogenase 1, mitochondrial; OsGDH1; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q852M0 glutamate dehydrogenase (EC 1.4.1.2) from Oryza sativa (see paper)
39% identity, 77% coverage of query (247 bits)
DHE3_ORYSJ / Q6H3Y7 Glutamate dehydrogenase 3, mitochondrial; OsGDH3; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
39% identity, 77% coverage of query (244 bits)
Q9YC65 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Aeropyrum pernix (see paper)
40% identity, 72% coverage of query (242 bits)
DHE2_ORYSJ / Q33E23 Glutamate dehydrogenase 2, mitochondrial; OsGDH2; EC 1.4.1.3 from Oryza sativa subsp. japonica (Rice) (see 7 papers)
38% identity, 77% coverage of query (238 bits)
gdhA / P28997 NAD-glutamate dehydrogenase subunit (EC 1.4.1.2) from Peptoniphilus asaccharolyticus (see paper)
DHE2_PEPAS / P28997 NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Peptoniphilus asaccharolyticus (Peptostreptococcus asaccharolyticus) (see 2 papers)
P28997 glutamate dehydrogenase (EC 1.4.1.2) from Peptoniphilus asaccharolyticus (see 2 papers)
40% identity, 71% coverage of query (235 bits)
P27346 glutamate dehydrogenase (EC 1.4.1.2) from Clostridioides difficile (see paper)
gluD / GB|AAA62756.1 NAD-specific glutamate dehydrogenase; EC 1.4.1.2 from Clostridium difficile (see paper)
42% identity, 71% coverage of query (234 bits)
Q9Y8I4 glutamate dehydrogenase (EC 1.4.1.2) from Pyrobaculum islandicum (see paper)
37% identity, 79% coverage of query (230 bits)
1v9lA / Q9Y8I4 L-glutamate dehydrogenase from pyrobaculum islandicum complexed with NAD (see paper)
37% identity, 79% coverage of query (230 bits)
DHE4_PYRCJ / A3MWK6 NADP(+)-dependent glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MWK6 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Pyrobaculum calidifontis (see paper)
33% identity, 80% coverage of query (224 bits)
DHE2_PYRCJ / A3MUY9 NAD(+)-dependent glutamate dehydrogenase; NAD-GDH; NAD-specific glutamate dehydrogenase; EC 1.4.1.2 from Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) (see paper)
A3MUY9 glutamate dehydrogenase (EC 1.4.1.2) from Pyrobaculum calidifontis (see paper)
33% identity, 79% coverage of query (219 bits)
Q93IM2 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Thermus thermophilus (see paper)
36% identity, 74% coverage of query (185 bits)
3aoeF / Q72IC0 Crystal structure of hetero-hexameric glutamate dehydrogenase from thermus thermophilus (leu bound form)
35% identity, 74% coverage of query (183 bits)
1bgvA / P24295 Glutamate dehydrogenase (see paper)
32% identity, 79% coverage of query (144 bits)
DHE2_CLOSY / P24295 NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Clostridium symbiosum (Bacteroides symbiosus) (see 4 papers)
P24295 glutamate dehydrogenase (EC 1.4.1.2) from [Clostridium] symbiosum (see 4 papers)
gdh / CAA77805.1 Glutamate Dehydrogenase from [Clostridium] symbiosum (see paper)
32% identity, 79% coverage of query (144 bits)
Build an alignment for CA265_RS03475 and 55 homologs with ≥ 30% identity
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Q8ILF7 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Plasmodium falciparum (see paper)
29% identity, 74% coverage of query (137 bits)
DHE4_PRERU / P95544 NAD(P)-specific glutamate dehydrogenase; NAD(P)-GDH; NAD(P)H-dependent glutamate dehydrogenase; EC 1.4.1.3 from Prevotella ruminicola (Bacteroides ruminicola) (see paper)
30% identity, 76% coverage of query (136 bits)
5gudE / A0A0U4QBJ6 Glutamate dehydrogenase from corynebacterium glutamicum (alpha- iminoglutarate/NADP+ complex) (see paper)
30% identity, 73% coverage of query (123 bits)
P31026 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Corynebacterium glutamicum (see paper)
30% identity, 73% coverage of query (123 bits)
A0A0U4QBJ6 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Corynebacterium glutamicum (see paper)
30% identity, 73% coverage of query (123 bits)
5ijzA Crystal structure of glutamate dehydrogenase(gdh) from corynebacterium glutamicum
30% identity, 73% coverage of query (123 bits)
5gudA Glutamate dehydrogenase from corynebacterium glutamicum (alpha- iminoglutarate/NADP+ complex)
30% identity, 73% coverage of query (123 bits)
A0A1V1FMC4 glutamate dehydrogenase [NAD(P)+] (EC 1.4.1.3) from Streptococcus equinus (see paper)
30% identity, 78% coverage of query (120 bits)
A0R3E3 glutamate dehydrogenase (NADP+) (EC 1.4.1.4) from Mycolicibacterium smegmatis (see paper)
30% identity, 76% coverage of query (118 bits)
DHE4_PSYT1 / Q9S1F9 NADP-specific glutamate dehydrogenase; NADP-GDH; EC 1.4.1.4 from Psychrobacter sp. (strain TAD1) (see paper)
28% identity, 74% coverage of query (118 bits)
P00369 NADP-specific glutamate dehydrogenase; NADP-GDH; NADP-dependent glutamate dehydrogenase; EC 1.4.1.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
30% identity, 81% coverage of query (107 bits)
5xwcA Crystal structure of aspergillus niger glutamate dehydrogenase complexed with alpha-iminoglutarate, 2-amino-2-hydroxyglutarate and NADP
28% identity, 79% coverage of query (96.3 bits)
5xw0A Crystal structure of aspergillus niger glutamate dehydrogenase complexed with isophthalate and NADPH
28% identity, 79% coverage of query (96.3 bits)
5xvxA Crystal structure of aspergillus niger glutamate dehydrogenase complexed with alpha-ketoglutarate and NADPH
28% identity, 79% coverage of query (96.3 bits)
5xvvB / B6V7E4 Crystal structure of forward inhibited aspergillus niger glutamate dehydrogenase with both apo- and alpha ketoglutarate bound subunits (see paper)
28% identity, 79% coverage of query (96.3 bits)
P78804 NADP-specific glutamate dehydrogenase; NADP-GDH; NADP-dependent glutamate dehydrogenase; EC 1.4.1.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
28% identity, 76% coverage of query (93.2 bits)
7ecsA Crystal structure of aspergillus terreus glutamate dehydrogenase (atgdh) complexed with malonate and NADPH
26% identity, 80% coverage of query (87.8 bits)
7ecrA / T2D1F5 Crystal structure of aspergillus terreus glutamate dehydrogenase (atgdh) complexed with succinate and adp-ribose (see paper)
26% identity, 80% coverage of query (87.8 bits)
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Lawrence Berkeley National Laboratory