Searching for up to 100 curated homologs for CA265_RS04665 FitnessBrowser__Pedo557:CA265_RS04665 (260 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BmulJ_04919 / A0A0H3KNE7 L-fucose dehydrogenase monomer (EC 1.1.1.435) from Burkholderia multivorans (strain ATCC 17616 / 249) (see paper)
LFUCD_BURM1 / A0A0H3KNE7 L-fucose dehydrogenase; EC 1.1.1.435 from Burkholderia multivorans (strain ATCC 17616 / 249) (see paper)
4gkbB / A0A0H3KNE7 Crystal structure of a short chain dehydrogenase homolog (target efi- 505321) from burkholderia multivorans, unliganded structure
52% identity, 100% coverage of query (254 bits)
4gvxA Crystal structure of a short chain dehydrogenase homolog (target efi- 505321) from burkholderia multivorans, with bound NADP and l-fucose
52% identity, 100% coverage of query (254 bits)
4gloA Crystal structure of a short chain dehydrogenase homolog (target efi- 505321) from burkholderia multivorans, with bound NAD
52% identity, 100% coverage of query (254 bits)
6ds1B / Q0PB28 Crystal structure of cj0485 dehydrogenase in complex with NADP+ (see paper)
44% identity, 100% coverage of query (224 bits)
A0A0G2SJM3 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Fimbriaphyllia ancora (see paper)
31% identity, 96% coverage of query (129 bits)
Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Pseudomonas aeruginosa (see paper)
33% identity, 96% coverage of query (127 bits)
7wbcA / A0A098BU97 Hydroxysteroid dehydrogenase wild-type complexed with NAD+ and (4s)-2- 2-methyl-2,4-pentanediol
33% identity, 97% coverage of query (123 bits)
ChlADR / Q9FZ42 aldehyde reductase (chloroplastic) (EC 1.1.1.2; EC 1.1.1.21) from Arabidopsis thaliana (see paper)
ADRC1_ARATH / Q9FZ42 NADPH-dependent aldehyde reductase 1, chloroplastic; AtChlADR1; Glucose and ribitol dehydrogenase homolog 1; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 96% coverage of query (121 bits)
1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
31% identity, 96% coverage of query (117 bits)
uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
31% identity, 96% coverage of query (117 bits)
GRDH_DAUCA / Q5KTS5 Glucose and ribitol dehydrogenase; Carrot ABA-induced in somatic embryos 5 protein; EC 1.1.1.- from Daucus carota (Wild carrot)
32% identity, 96% coverage of query (115 bits)
Q9WYD3 D-arabinitol 2-dehydrogenase (EC 1.1.1.250) from Thermotoga maritima (see paper)
34% identity, 96% coverage of query (114 bits)
3ijrF / A0A6L8PL20 2.05 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD+
34% identity, 96% coverage of query (109 bits)
3i3oA 2.06 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD-acetone
34% identity, 96% coverage of query (109 bits)
6emmA / Q9BPX1 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with salicylic acid
31% identity, 88% coverage of query (107 bits)
DHB14_HUMAN / Q9BPX1 17-beta-hydroxysteroid dehydrogenase 14; 17-beta-HSD 14; 17-beta-hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; Retinal short-chain dehydrogenase/reductase retSDR3; Short chain dehydrogenase/reductase family 47C member 1; EC 1.1.1.62 from Homo sapiens (Human) (see 2 papers)
Q9BPX1 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Homo sapiens (see 2 papers)
31% identity, 88% coverage of query (107 bits)
NR_NARAP / A0A1C9II22 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus aff. pseudonarcissus MK-2014 (Daffodil) (see paper)
NR_NARPS / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus pseudonarcissus (Daffodil) (see 2 papers)
5ff9B / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and tyramine (see paper)
34% identity, 95% coverage of query (107 bits)
6zt2A 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with 3-chloro-2,6-difluorophenol
31% identity, 88% coverage of query (107 bits)
6zdiA 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with 2-fluoro-5-nitrophenol
31% identity, 88% coverage of query (107 bits)
6zdeA 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with pentafluorophenol
31% identity, 88% coverage of query (107 bits)
5en4A Complex of 17-beta-hydroxysteroid dehydrogenase type 14 with inhibitor.
31% identity, 88% coverage of query (107 bits)
5l7wA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
31% identity, 88% coverage of query (107 bits)
6gtbA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fb211
31% identity, 88% coverage of query (107 bits)
5o7cA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
31% identity, 88% coverage of query (107 bits)
5o6zA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
31% identity, 88% coverage of query (107 bits)
5o6oA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor
31% identity, 88% coverage of query (107 bits)
5o42A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor.
31% identity, 88% coverage of query (107 bits)
5hs6A Human 17beta-hydroxysteroid dehydrogenase type 14 in complex with estrone
31% identity, 88% coverage of query (107 bits)
5o72A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
31% identity, 88% coverage of query (107 bits)
6qckA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fb262
31% identity, 88% coverage of query (107 bits)
5l7yA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
31% identity, 88% coverage of query (107 bits)
5l7tA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
31% identity, 88% coverage of query (107 bits)
6gtuA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fragment j6
31% identity, 88% coverage of query (107 bits)
5icmA 17beta-hydroxysteroid dehydrogenase type 14 in complex with a non- steroidal inhibitor
31% identity, 88% coverage of query (107 bits)
5o6xA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
31% identity, 88% coverage of query (107 bits)
5o43A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor.
31% identity, 88% coverage of query (107 bits)
5fffA Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and piperonal
34% identity, 95% coverage of query (107 bits)
cpnA / Q8GAV9 cyclopentanol dehydrogenase (EC 1.1.1.163) from Comamonas sp. (strain NCIMB 9872) (see 2 papers)
CPNA_COMS9 / Q8GAV9 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas sp. (strain NCIMB 9872) (see paper)
CPNA_COMTE / Q937L4 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
cpmB / CAD10799.1 cyclohexanol dehydrogenase from Comamonas testosteroni (see paper)
31% identity, 95% coverage of query (105 bits)
5t2uA / A0R723 Short chain dehydrogenase/reductase family protein (see paper)
32% identity, 96% coverage of query (105 bits)
A0R723 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); acetoacetyl-CoA reductase (EC 1.1.1.36) from Mycolicibacterium smegmatis (see paper)
32% identity, 96% coverage of query (105 bits)
LINC_SPHIU / D4YYG1 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
31% identity, 97% coverage of query (105 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
31% identity, 97% coverage of query (105 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
31% identity, 96% coverage of query (104 bits)
DCXR_CAEEL / Q21929 L-xylulose reductase; XR; Dicarbonyl/L-xylulose reductase; DCXR; Short-chain dehydrogenase 21; EC 1.1.1.10 from Caenorhabditis elegans (see 2 papers)
Q21929 L-xylulose reductase (EC 1.1.1.10) from Caenorhabditis elegans (see paper)
33% identity, 97% coverage of query (104 bits)
bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
31% identity, 96% coverage of query (104 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
31% identity, 95% coverage of query (103 bits)
BWI76_RS01745 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) from Klebsiella michiganensis M5al
32% identity, 96% coverage of query (102 bits)
Build an alignment for CA265_RS04665 and 47 homologs with ≥ 30% identity
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W5VJM4 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
28% identity, 98% coverage of query (102 bits)
A0A1E3M3N6 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acinetobacter baumannii (see paper)
6zzsD / A0A1E3M3N6 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (see paper)
29% identity, 97% coverage of query (102 bits)
A0A1Z3FWF0 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Rhodococcus sp. P14 (see paper)
31% identity, 97% coverage of query (102 bits)
6zzqA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and acetoacetate
30% identity, 95% coverage of query (102 bits)
1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
30% identity, 95% coverage of query (102 bits)
Q9AR59 tropinone reductase I (EC 1.1.1.206) from Solanum tuberosum (see paper)
33% identity, 96% coverage of query (101 bits)
B6FYX7 12alpha-hydroxysteroid dehydrogenase (EC 1.1.1.176) from Peptacetobacter hiranonis (see paper)
32% identity, 95% coverage of query (101 bits)
A0A2D0WG37 cyclohexanol dehydrogenase (EC 1.1.1.245) from Acidovorax sp. (see paper)
30% identity, 95% coverage of query (101 bits)
U5PUZ1 tropinone reductase I (EC 1.1.1.206) from Withania somnifera (see paper)
31% identity, 96% coverage of query (101 bits)
TRNH3_ARATH / Q9ZW03 Tropinone reductase homolog At2g29150; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 95% coverage of query (100 bits)
W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
28% identity, 98% coverage of query (100 bits)
A0A0E3ZP28 L-xylulose reductase (EC 1.1.1.10) from Escherichia coli (see paper)
31% identity, 99% coverage of query (100 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
31% identity, 96% coverage of query (100 bits)
tsaC / P94681 4-sulfobenzyl alcohol dehydrogenase subunit (EC 1.1.1.257) from Comamonas testosteroni (see paper)
TSAC_COMTE / P94681 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2; Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; EC 1.2.1.62 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
29% identity, 96% coverage of query (99.8 bits)
C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Ralstonia sp. (see paper)
4bmsF / C0IR58 Short chain alcohol dehydrogenase from ralstonia sp. Dsm 6428 in complex with NADPH
29% identity, 95% coverage of query (99.8 bits)
A8R3J3 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see paper)
30% identity, 95% coverage of query (99.4 bits)
6ci9D / A0QP46 Rmm microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure (see paper)
30% identity, 97% coverage of query (99.0 bits)
AF255341 / Q9NBB5 3-dehydroecdysone-3α-reductase from Spodoptera littoralis (see 3 papers)
31% identity, 94% coverage of query (99.0 bits)
Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
29% identity, 95% coverage of query (99.0 bits)
TRN1_COCOF / A7DY56 Tropinone reductase; EC 1.1.1.206; EC 1.1.1.236 from Cochlearia officinalis (Common scurvygrass) (see paper)
A7DY56 tropinone reductase I (EC 1.1.1.206); tropinone reductase II (EC 1.1.1.236) from Cochlearia officinalis (see paper)
30% identity, 96% coverage of query (99.0 bits)
6y4dA Crystal structure of a short-chain dehydrogenase/reductase (sdr) from zephyranthes treatiae in complex with NADP+ (see paper)
33% identity, 95% coverage of query (99.0 bits)
1hdcA / P19992 Mechanism of inhibition of 3alpha,20beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor (see paper)
31% identity, 96% coverage of query (98.6 bits)
7v0hG / B4E6Z1 Crystal structure of putative glucose 1-dehydrogenase from burkholderia cenocepacia in complex with NADP and a potential reaction product
33% identity, 95% coverage of query (98.6 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
31% identity, 96% coverage of query (98.6 bits)
2hsdA The refined three-dimensional structure of 3alpha,20beta- hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
31% identity, 96% coverage of query (98.6 bits)
GALD_RHIME / Q92RN6 Probable galactose dehydrogenase GalD; EC 1.1.1.- from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
29% identity, 95% coverage of query (97.8 bits)
A0A6B7HCZ2 tropinone reductase I (EC 1.1.1.206) from Przewalskia tangutica (see paper)
31% identity, 96% coverage of query (97.8 bits)
R4QQK2 tropinone reductase I (EC 1.1.1.206) from Anisodus luridus (see paper)
31% identity, 96% coverage of query (97.8 bits)
PRF|1611236A 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Streptomyces exfoliatus (see paper)
31% identity, 96% coverage of query (97.8 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
29% identity, 96% coverage of query (97.8 bits)
B2L2W8 tropinone reductase I (EC 1.1.1.206) from Anisodus acutangulus (see 3 papers)
31% identity, 96% coverage of query (97.1 bits)
L7QI79 tropinone reductase I (EC 1.1.1.206) from Withania coagulans (see paper)
31% identity, 96% coverage of query (97.1 bits)
Shewana3_2071 L-arabinose 1-dehydrogenase (EC 1.1.1.46) from Shewanella sp. ANA-3
28% identity, 96% coverage of query (96.7 bits)
TR2 / P50163 tropinone reductase (EC 1.1.1.236) from Datura stramonium (see paper)
TRN2_DATST / P50163 Tropinone reductase 2; Tropinone reductase II; TR-II; EC 1.1.1.236 from Datura stramonium (Jimsonweed) (Common thornapple) (see paper)
P50163 tropinone reductase II (EC 1.1.1.236) from Datura stramonium (see 3 papers)
31% identity, 95% coverage of query (96.7 bits)
2ae2A / P50163 Tropinone reductase-ii complexed with NADP+ and pseudotropine (see paper)
31% identity, 95% coverage of query (96.7 bits)
LINX_SPHIU / D4Z260 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX; 2,5-DDOL dehydrogenase; EC 1.1.1.- from Sphingobium indicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) (Sphingobium japonicum) (see paper)
31% identity, 95% coverage of query (96.7 bits)
6ihhA Crystal structure of rasadh f12 from ralstonia.Sp in complex with NADPH and a6o
29% identity, 95% coverage of query (96.7 bits)
1ipfA Tropinone reductase-ii complexed with NADPH and tropinone
31% identity, 95% coverage of query (96.7 bits)
1ipeA Tropinone reductase-ii complexed with NADPH
31% identity, 95% coverage of query (96.7 bits)
A0A545BBS8 pseudoephedrine dehydrogenase (EC 1.1.1.422) from Arthrobacter sp. TS-15 (see paper)
30% identity, 96% coverage of query (96.3 bits)
6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
30% identity, 96% coverage of query (96.3 bits)
TRII / CAB52307.1 tropinone reductase II from Solanum tuberosum (see paper)
29% identity, 96% coverage of query (96.3 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
27% identity, 95% coverage of query (96.3 bits)
TPRL1_ERYCB / H9BFQ0 Tropinone reductase-like 1; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
33% identity, 95% coverage of query (95.9 bits)
1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
31% identity, 96% coverage of query (95.9 bits)
TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
31% identity, 96% coverage of query (95.9 bits)
4iqgD / Q12GY8 Crystal structure of bpro0239 oxidoreductase from polaromonas sp. Js666 in NADP bound form
30% identity, 94% coverage of query (95.5 bits)
A0A088MI02 tropinone reductase I (EC 1.1.1.206) from Brugmansia arborea (see paper)
32% identity, 96% coverage of query (95.5 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
29% identity, 96% coverage of query (95.5 bits)
TPRL2_ERYCB / H9BFQ1 Tropinone reductase-like 2; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
33% identity, 95% coverage of query (95.5 bits)
2rh4B / P16544 Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin (see paper)
27% identity, 95% coverage of query (95.5 bits)
2rh4A Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin
27% identity, 95% coverage of query (95.5 bits)
1w4zA Structure of actinorhodin polyketide (actiii) reductase
27% identity, 95% coverage of query (95.5 bits)
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