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Searching for up to 100 curated homologs for CA265_RS06120 FitnessBrowser__Pedo557:CA265_RS06120 (351 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

Removed hits that are identical to the query, leaving 23

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Echvi_0695 UDP-glucose--hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Echinicola vietnamensis KMM 6221, DSM 17526
    56% identity, 98% coverage of query (427 bits)

GalB / b0758 galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Escherichia coli K-12 substr. MG1655 (see 19 papers)
galT / P09148 galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Escherichia coli (strain K12) (see 16 papers)
GAL7_ECOLI / P09148 Galactose-1-phosphate uridylyltransferase; Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; EC 2.7.7.12 from Escherichia coli (strain K12) (see 5 papers)
P09148 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Escherichia coli (see 5 papers)
    51% identity, 97% coverage of query (371 bits)

1gupA / P09148 Structure of nucleotidyltransferase complexed with udp-galactose (see paper)
    50% identity, 97% coverage of query (367 bits)

1guqA Structure of nucleotidyltransferase complexed with udp-glucose
    50% identity, 97% coverage of query (367 bits)

1hxpA Nucleotide transferase
    50% identity, 97% coverage of query (365 bits)

GAL7_HYPJE / Q96UI1 Galactose-1-phosphate uridylyltransferase; Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; EC 2.7.7.12 from Hypocrea jecorina (Trichoderma reesei) (see paper)
    47% identity, 97% coverage of query (357 bits)

GALT / P07902 galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Homo sapiens (see 13 papers)
GALT_HUMAN / P07902 Galactose-1-phosphate uridylyltransferase; Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; EC 2.7.7.12 from Homo sapiens (Human) (see 28 papers)
P07902 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Homo sapiens (see 9 papers)
    50% identity, 99% coverage of query (353 bits)

Q03249 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Mus musculus (see 2 papers)
    49% identity, 100% coverage of query (349 bits)

A2AMS3 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Mus musculus (see paper)
    49% identity, 100% coverage of query (348 bits)

P43424 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Rattus norvegicus (see paper)
    48% identity, 100% coverage of query (346 bits)

1hxpB Nucleotide transferase
    49% identity, 97% coverage of query (346 bits)

6gqdA / P07902 Structure of human galactose-1-phosphate uridylyltransferase (galt), with crystallization epitope mutations a21y:a22t:t23p:r25l
    49% identity, 98% coverage of query (344 bits)

5in3A Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase
    49% identity, 95% coverage of query (325 bits)

Q8ZXN7 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Pyrobaculum aerophilum (see 2 papers)
    30% identity, 93% coverage of query (131 bits)

6k5zB / Q8ZXN7 Structure of uridylyltransferase (see paper)
    30% identity, 93% coverage of query (131 bits)

Build an alignment

Build an alignment for CA265_RS06120 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

M4MCS2 UDP-glucose-hexose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Bifidobacterium bifidum (see paper)
    26% identity, 95% coverage of query (121 bits)

AGLUP_ARATH / Q9FK51 ADP-glucose phosphorylase; ADP-glucose:phosphate adenylyltransferase; EC 2.7.7.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    26% identity, 96% coverage of query (108 bits)

6k9zA Structure of uridylyltransferase mutant
    28% identity, 93% coverage of query (108 bits)

2h39B / Q9FK51 Crystal structure of an adp-glucose phosphorylase from arabidopsis thaliana with bound adp-glucose
    25% identity, 95% coverage of query (102 bits)

1z84A X-ray structure of galt-like protein from arabidopsis thaliana at5g18200
    24% identity, 95% coverage of query (99.4 bits)

UT / Q19TV7 galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) from Cucumis melo (see paper)
    25% identity, 95% coverage of query (94.4 bits)

hygO / Q2MFS4 NDP-heptose synthase from Streptomyces hygroscopicus subsp. hygroscopicus (see paper)
    24% identity, 94% coverage of query (94.0 bits)

apt / Q9LA72 adenylylsulfate:phosphate adenylyltransferase subunit (EC 2.7.7.5) from Thiobacillus denitrificans (see paper)
Q9LA72 sulfate adenylyltransferase (ADP) (EC 2.7.7.5) from Thiobacillus denitrificans (see paper)
    23% identity, 96% coverage of query (85.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory