Searching for up to 100 curated homologs for CA265_RS08390 FitnessBrowser__Pedo557:CA265_RS08390 (310 a.a.)
Found high-coverage hits (≥70%) to 37 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
A9CL94 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
30% identity, 86% coverage of query (135 bits)
Build an alignment for CA265_RS08390 and 1 homologs with ≥ 30% identity
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4pfmA / A9DKW4 Shewanella benthica dhdps with lysine and pyruvate
25% identity, 71% coverage of query (75.5 bits)
dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
23% identity, 85% coverage of query (71.6 bits)
dapA2 dihydrodipicolinate synthase; EC 4.2.1.52 from Bacillus anthracis (see paper)
25% identity, 85% coverage of query (71.2 bits)
4dxvA / D0CFC3 Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
24% identity, 87% coverage of query (70.5 bits)
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
24% identity, 87% coverage of query (70.5 bits)
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
24% identity, 87% coverage of query (70.5 bits)
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
24% identity, 87% coverage of query (70.5 bits)
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
24% identity, 87% coverage of query (70.5 bits)
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
24% identity, 87% coverage of query (70.5 bits)
A5F699 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Vibrio cholerae (see paper)
19% identity, 85% coverage of query (70.1 bits)
DAPA_PSEAE / Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Pseudomonas aeruginosa (see 2 papers)
22% identity, 85% coverage of query (69.3 bits)
3nevA / P75682 Crystal structure of yage, a prophage protein from e. Coli k12 in complex with kdgal (see paper)
26% identity, 73% coverage of query (67.8 bits)
dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
24% identity, 85% coverage of query (67.8 bits)
YagE / b0268 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yagE / P75682 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli (strain K12) (see 8 papers)
YAGE_ECOLI / P75682 Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE; KDG aldolase YagE; Putative 2-dehydro-3-deoxy-D-pentonate aldolase YagE; EC 4.1.2.51; EC 4.1.2.28 from Escherichia coli (strain K12) (see 4 papers)
P75682 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20) from Escherichia coli (see paper)
26% identity, 73% coverage of query (67.8 bits)
4ptnA Crystal structure of yage, a kdg aldolase protein in complex with magnesium cation coordinated l-glyceraldehyde
26% identity, 73% coverage of query (67.8 bits)
4onvA Crystal structure of yage, a kdg aldolase protein in complex with 2- keto-3-deoxy gluconate
26% identity, 73% coverage of query (67.8 bits)
4oe7D Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
26% identity, 73% coverage of query (67.8 bits)
4oe7B Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
26% identity, 73% coverage of query (67.8 bits)
4oe7A Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
26% identity, 73% coverage of query (67.8 bits)
dhdps / CAC50571.1 dihydrodipicolinate synthetase from Yersinia enterocolitica (see paper)
19% identity, 92% coverage of query (63.9 bits)
4i7wA / F0L8Z6 Agrobacterium tumefaciens dhdps with lysine and pyruvate
24% identity, 85% coverage of query (60.1 bits)
Q8NMD2 N-acetylneuraminate lyase (EC 4.1.3.3) from Corynebacterium glutamicum (see paper)
25% identity, 71% coverage of query (58.5 bits)
YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
18% identity, 86% coverage of query (58.5 bits)
3puoA / Q9I4W3 Crystal structure of dihydrodipicolinate synthase from pseudomonas aeruginosa(psdhdps)complexed with l-lysine at 2.65a resolution (see paper)
22% identity, 85% coverage of query (57.8 bits)
3s8hA Structure of dihydrodipicolinate synthase complexed with 3- hydroxypropanoic acid(hpa)at 2.70 a resolution
22% identity, 85% coverage of query (57.8 bits)
5c55A / Q8NMD2 Crystal structure of the y138f mutant of c.Glutamicum n- acetylneuraminic acid lyase in complex with pyruvate
25% identity, 71% coverage of query (57.4 bits)
Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
22% identity, 72% coverage of query (55.8 bits)
DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
24% identity, 93% coverage of query (53.9 bits)
1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
24% identity, 93% coverage of query (53.9 bits)
5t25A / B7M7I1 Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
21% identity, 87% coverage of query (53.1 bits)
DapA / b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
dapA / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12) (see 23 papers)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 11 papers)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (see 15 papers)
21% identity, 87% coverage of query (53.1 bits)
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
21% identity, 87% coverage of query (53.1 bits)
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site.
20% identity, 87% coverage of query (52.0 bits)
A9CFV4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
20% identity, 80% coverage of query (49.3 bits)
7mjfA Crystal structure of candidatus liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
20% identity, 92% coverage of query (44.3 bits)
7lvlA / A0A0F4VK59 Dihydrodipicolinate synthase bound with allosteric inhibitor (s)- lysine from candidatus liberibacter solanacearum
20% identity, 92% coverage of query (44.3 bits)
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Lawrence Berkeley National Laboratory