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Searching for up to 100 curated homologs for CA265_RS08550 FitnessBrowser__Pedo557:CA265_RS08550 (383 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SUGCT / Q9HAC7 succinyl-CoA-glutarate CoA-transferase (EC 2.8.3.13) from Homo sapiens (see 3 papers)
Q9HAC7 succinate-hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) from Homo sapiens (see paper)
    32% identity, 98% coverage of query (198 bits)

SUCHY_HUMAN / Q9HAC7 Succinate--hydroxymethylglutarate CoA-transferase; Dermal papilla-derived protein 13; SuccinylCoA:glutarate-CoA transferase; EC 2.8.3.13 from Homo sapiens (Human) (see 3 papers)
    32% identity, 98% coverage of query (198 bits)

acuN / C8YX88 AcuN from Halomonas sp. HTNK1 (see paper)
    31% identity, 98% coverage of query (196 bits)

YfdE / b2371 acetyl-CoA:oxalate CoA-transferase (EC 2.8.3.19) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
yfdE / P76518 acetyl-CoA:oxalate CoA-transferase (EC 2.8.3.19) from Escherichia coli (strain K12) (see paper)
ACOCT_ECOLI / P76518 Acetyl-CoA:oxalate CoA-transferase; ACOCT; Acetyl-coenzyme A transferase; CoA:oxalate CoA-transferase; EC 2.8.3.19 from Escherichia coli (strain K12) (see 3 papers)
P76518 CoA:oxalate CoA-transferase (EC 2.8.3.19) from Escherichia coli (see paper)
    33% identity, 84% coverage of query (182 bits)

caiB / Q7CXU0 succinate—lglutarate CoA-transferase (EC 2.8.3.13) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
SGCOT_AGRFC / Q7CXU0 Succinate--glutarate CoA-transferase; EC 2.8.3.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
    31% identity, 99% coverage of query (177 bits)

ACOCT_ACEAC / A9X6P9 Acetyl-CoA:oxalate CoA-transferase; ACOCT; Acetyl-coenzyme A transferase; CoA:oxalate CoA-transferase; CoAT3; EC 2.8.3.19 from Acetobacter aceti (see paper)
    31% identity, 98% coverage of query (176 bits)

gcdG / Q88RH1 succinyl-CoA-glutarate CoA-transferase (EC 2.8.3.13) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    32% identity, 96% coverage of query (171 bits)

act / B9U6P4 acyl-CoA:3-sulfinopropionate CoA-transferase from Variovorax paradoxus (see paper)
    31% identity, 83% coverage of query (167 bits)

AO356_10845 succinyl-CoA-glutarate CoA-transferase (EC 2.8.3.13) from Pseudomonas fluorescens FW300-N2C3
    32% identity, 97% coverage of query (167 bits)

Build an alignment

Build an alignment for CA265_RS08550 and 9 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

gbuC / A0A415DZ14 γ-butyrobetaine CoA transferase GbuC component from Emergencia timonensis (see paper)
    29% identity, 99% coverage of query (165 bits)

act / CAG29276.1 beta-alanine CoA-transferase from Anaerotignum propionicum (see paper)
    30% identity, 97% coverage of query (158 bits)

FDB20_FUSPC / K3VD64 Acyl-CoA transferase FPSE_08120; Fusarium detoxification of benzoxazolinone cluster protein FPSE_08120; FDB cluster protein FPSE_08120; EC 2.8.3.- from Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot fungus) (see 3 papers)
    28% identity, 99% coverage of query (156 bits)

A0A1G7S280 formyl-CoA transferase (EC 2.8.3.16) from Pseudomonas abietaniphila (see paper)
    28% identity, 100% coverage of query (155 bits)

SMTB_CHLAU / Q1KLK0 Succinyl-CoA--L-malate CoA-transferase beta subunit; EC 2.8.3.22 from Chloroflexus aurantiacus (see paper)
    29% identity, 98% coverage of query (153 bits)

MCT_HALHT / G0HQ31 Succinyl-CoA:mesaconate CoA-transferase; Mesaconate CoA-transferase; EC 2.8.3.26 from Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755) (see paper)
G0HQ31 succinyl-CoA:mesaconate CoA transferase (EC 2.8.3.26) from Haloarcula hispanica (see paper)
    32% identity, 79% coverage of query (149 bits)

mct / Q5V468 succinyl-CoA:mesaconate CoA transferase (EC 2.8.3.26) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see paper)
MCT_HALMA / Q5V468 Succinyl-CoA:mesaconate CoA-transferase; EC 2.8.3.26 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) (see paper)
    32% identity, 79% coverage of query (148 bits)

COATR_MYCTU / P96877 Probable fatty acyl-CoA transferase Rv3272; EC 2.8.3.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    29% identity, 96% coverage of query (139 bits)

5yx6A / P96877 Crystal structure of rv3272 from m. Tuberculosis orthorhombic form (see paper)
    28% identity, 96% coverage of query (132 bits)

frc / O06644 formyl-coenzyme A transferase monomer (EC 2.8.3.16) from Oxalobacter formigenes (see 3 papers)
FCTA_OXAFO / O06644 Formyl-CoA:oxalate CoA-transferase; FCOCT; Formyl-coenzyme A transferase; EC 2.8.3.16 from Oxalobacter formigenes (see 6 papers)
O06644 formyl-CoA transferase (EC 2.8.3.16) from Oxalobacter formigenes (see 7 papers)
    28% identity, 100% coverage of query (125 bits)

1p5rA / O06644 Formyl-coa transferase in complex with coenzyme a (see paper)
    28% identity, 99% coverage of query (124 bits)

2vjoA Formyl-coa transferase mutant variant q17a with aspartyl-coa thioester intermediates and oxalate
    28% identity, 99% coverage of query (123 bits)

2vjkA Formyl-coa transferase with aspartyl-coa thioester intermediate derived from oxalyl-coa
    28% identity, 99% coverage of query (123 bits)

1t4cA Formyl-coa transferase in complex with oxalyl-coa
    28% identity, 99% coverage of query (123 bits)

1t3zA Formyl-coa tranferase mutant asp169 to ser
    28% identity, 99% coverage of query (120 bits)

AMACR / Q9UHK6 α-methylacyl-CoA racemase (EC 5.1.99.4) from Homo sapiens (see 16 papers)
AMACR_HUMAN / Q9UHK6 Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; EC 5.1.99.4 from Homo sapiens (Human) (see 5 papers)
Q9UHK6 alpha-methylacyl-CoA racemase (EC 5.1.99.4) from Homo sapiens (see 9 papers)
    25% identity, 98% coverage of query (108 bits)

hadA / Q188I3 isocaprenoyl-CoA:2-hydroxyisocaproate CoA-transferase (EC 2.8.3.24) from Clostridioides difficile (strain 630) (see 2 papers)
    28% identity, 98% coverage of query (107 bits)

hadA / GI|54781347 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); EC 1.2.4.4 from Clostridium difficile (see 2 papers)
    28% identity, 98% coverage of query (107 bits)

AMACR_MOUSE / O09174 Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; EC 5.1.99.4 from Mus musculus (Mouse) (see paper)
    25% identity, 98% coverage of query (104 bits)

ptmU4 / D8L2W6 3-amino-2,4-dihydroxybenzoylsulfanide synthase from Streptomyces platensis (see 3 papers)
    29% identity, 82% coverage of query (103 bits)

CEFD2_HAPCH / Q8J0F0 Isopenicillin N epimerase component 2; IPN epimerase component 2; Isopenicillin N epimerase acyl-CoA racemase component; EC 5.1.1.17; EC 5.1.99.- from Hapsidospora chrysogena (Acremonium chrysogenum) (see paper)
    29% identity, 80% coverage of query (101 bits)

Amacr / P70473 α-methylacyl-CoA racemase (EC 5.1.99.4) from Rattus norvegicus (see 4 papers)
AMACR_RAT / P70473 Alpha-methylacyl-CoA racemase; 2-arylpropionyl-CoA epimerase; 2-methylacyl-CoA racemase; EC 5.1.99.4 from Rattus norvegicus (Rat) (see 4 papers)
    25% identity, 83% coverage of query (97.8 bits)

YaaN / b0038 γ-butyrobetainyl-CoA:carnitine CoA transferase (EC 2.8.3.21) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
caiB / P31572 γ-butyrobetainyl-CoA:carnitine CoA transferase (EC 2.8.3.21) from Escherichia coli (strain K12) (see 5 papers)
CAIB_ECOLI / P31572 L-carnitine CoA-transferase; Crotonobetainyl-CoA:carnitine CoA-transferase; EC 2.8.3.21 from Escherichia coli (strain K12) (see 2 papers)
P31572 L-carnitine CoA-transferase (EC 2.8.3.21) from Escherichia coli (see 3 papers)
    27% identity, 89% coverage of query (86.3 bits)

1xvtA / P31572 Crystal structure of native caib in complex with coenzyme a (see paper)
    27% identity, 89% coverage of query (86.3 bits)

1xvvA Crystal structure of caib mutant d169a in complex with carnitinyl-coa
    27% identity, 89% coverage of query (83.2 bits)

CAIB_PROSL / Q8GB19 L-carnitine CoA-transferase; Crotonobetainyl-CoA:carnitine CoA-transferase; EC 2.8.3.21 from Proteus sp. (strain LE138) (see paper)
Q8GB19 L-carnitine CoA-transferase (EC 2.8.3.21) from Proteus sp. (see 2 papers)
caiB / CAD48580.1 betainyl-CoA transferase from Proteus sp. LE138 (see paper)
    26% identity, 75% coverage of query (77.8 bits)

dddD / A6W2K8 dimethylsulfoniopropanoate:acetyl-CoA transferase from Marinomonas sp. (strain MWYL1) (see 2 papers)
DDDD_MARMS / A6W2K8 CoA-transferase/lyase DddD; EC 2.-.-.- from Marinomonas sp. (strain MWYL1) (see 2 papers)
    23% identity, 83% coverage of query (63.2 bits)

8apqA / A9WC36 Camct - mesaconyl-coa c1:c4 coa transferase of chloroflexus aurantiacus (see paper)
    23% identity, 97% coverage of query (61.2 bits)

8apqB Camct - mesaconyl-coa c1:c4 coa transferase of chloroflexus aurantiacus
    23% identity, 97% coverage of query (61.2 bits)

mct / A9WC36 mesaconyl-C1-CoA-C4-CoA transferase monomer (EC 5.4.1.3) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
MCT_CHLAA / A9WC36 2-methylfumaryl-CoA isomerase; EC 5.4.1.3 from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
A9WC36 2-methylfumaryl-CoA isomerase (EC 5.4.1.3) from Chloroflexus aurantiacus (see paper)
    23% identity, 97% coverage of query (60.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory