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Searching for up to 100 curated homologs for CA265_RS09660 CA265_RS09660 phosphoglucomutase (578 a.a.)

Found high-coverage hits (≥70%) to 31 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pgcA / P18159 α-phosphoglucomutase (EC 5.4.2.2) from Bacillus subtilis (strain 168) (see paper)
PGCA_BACSU / P18159 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
    48% identity, 88% coverage of query (491 bits)

pgmA / CAB96418.1 phosphoglucomutase from Streptococcus thermophilus (see paper)
    44% identity, 91% coverage of query (440 bits)

PGCA_STAA8 / Q2FVC1 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    38% identity, 91% coverage of query (342 bits)

PGM3_SCHPO / O74478 Probable phosphoribomutase; PRM; Phosphoglucomutase 3 homolog; PGM 3 homolog; EC 5.4.2.7 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    35% identity, 95% coverage of query (306 bits)

PGM2 / Q96G03 phosphoglucomutase-2 (EC 5.4.2.2; EC 5.4.2.7) from Homo sapiens (see 2 papers)
PGM2_HUMAN / Q96G03 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-2; EC 5.4.2.7; EC 5.4.2.2 from Homo sapiens (Human) (see 2 papers)
    33% identity, 98% coverage of query (298 bits)

PGM2_MOUSE / Q7TSV4 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-1; Phosphoglucomutase-2; PGM 2; EC 5.4.2.7; EC 5.4.2.2 from Mus musculus (Mouse) (see paper)
    32% identity, 98% coverage of query (291 bits)

C6L2F4 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Toxoplasma gondii (see paper)
    33% identity, 99% coverage of query (287 bits)

PGM2L_HUMAN / Q6PCE3 Glucose 1,6-bisphosphate synthase; PMMLP; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Homo sapiens (Human) (see 3 papers)
    32% identity, 99% coverage of query (275 bits)

PGM2L_MOUSE / Q8CAA7 Glucose 1,6-bisphosphate synthase; Phosphoglucomutase-2-like 1; EC 2.7.1.106 from Mus musculus (Mouse) (see paper)
    33% identity, 94% coverage of query (274 bits)

PGM3_YEAST / Q03262 Phosphoribomutase; PRM; Phosphoglucomutase 3; PGM 3; EC 5.4.2.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
    32% identity, 97% coverage of query (267 bits)

Build an alignment

Build an alignment for CA265_RS09660 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PGMMM_THEKO / Q68BJ6 Phosphoglucomutase/phosphomannomutase; PGM/PMM; EC 5.4.2.2; EC 5.4.2.8 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    27% identity, 88% coverage of query (124 bits)

PH0923 / O58651 phosphomannose mutase (EC 5.4.2.8) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
1wqaA / O58651 Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
    27% identity, 87% coverage of query (120 bits)

P74027 glucose-1,6-bisphosphate synthase from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
    25% identity, 88% coverage of query (88.2 bits)

celB / AAA21561.1 phosphoglucomutase from Komagataeibacter xylinus (see paper)
    25% identity, 94% coverage of query (87.4 bits)

2fuvA / Q8ZQW9 Phosphoglucomutase from salmonella typhimurium.
    25% identity, 89% coverage of query (84.3 bits)

A0A0H3NJ17 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
Q8ZQW9 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    25% identity, 89% coverage of query (84.0 bits)

Blu / b0688 phosphoglucomutase (EC 5.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
pgm / P36938 phosphoglucomutase (EC 5.4.2.2) from Escherichia coli (strain K12) (see 11 papers)
PGM_ECOLI / P36938 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Escherichia coli (strain K12) (see 2 papers)
pgm / GB|ABB65241.1 phosphoglucomutase; EC 5.4.2.2 from Escherichia coli K12 (see 6 papers)
    24% identity, 89% coverage of query (77.4 bits)

GLMM_STRR6 / Q8DP16 Phosphoglucosamine mutase; EC 5.4.2.10 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
    26% identity, 75% coverage of query (76.6 bits)

GLMM_HELPY / P25177 Phosphoglucosamine mutase; EC 5.4.2.10 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see 2 papers)
    23% identity, 75% coverage of query (75.1 bits)

7omlA Bacillus subtilis phosphoglucomutase glmm (metal bound)
    25% identity, 85% coverage of query (62.8 bits)

7ojrA / O34824 Bacillus subtilis phosphoglucomutase glmm (phosphate bound) (see paper)
    25% identity, 85% coverage of query (62.8 bits)

PGM_DROME / Q9VUY9 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Drosophila melanogaster (Fruit fly) (see paper)
    23% identity, 77% coverage of query (52.0 bits)

6snoA / P36871 Crystal structures of human pgm1 isoform 2 (see paper)
    23% identity, 91% coverage of query (52.0 bits)

PGM1 / P36871 phosphoglucomutase-1 (EC 5.4.2.2) from Homo sapiens (see 3 papers)
PGM1_HUMAN / P36871 Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Homo sapiens (Human) (see 8 papers)
P36871 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Homo sapiens (see 4 papers)
    23% identity, 85% coverage of query (52.0 bits)

6snqA Crystal structures of human pgm1 isoform 2
    23% identity, 76% coverage of query (51.2 bits)

5jn5A Crystal structure of the d263y missense variant of human pgm1
    24% identity, 70% coverage of query (50.8 bits)

7s0wB / P36871 Crystal structure of the t337m variant of human pgm-1 (see paper)
    24% identity, 70% coverage of query (48.1 bits)

PGM1_RABIT / P00949 Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Oryctolagus cuniculus (Rabbit) (see 3 papers)
    24% identity, 75% coverage of query (47.0 bits)

3pmgA Structure of rabbit muscle phosphoglucomutase at 2.4 angstroms resolution. Use of freezing point depressant and reduced temperature to enhance diffractivity
    24% identity, 75% coverage of query (47.0 bits)

1c4gA Phosphoglucomutase vanadate based transition state analog complex
    24% identity, 75% coverage of query (47.0 bits)

1c47A Binding driven structural changes in crystaline phosphoglucomutase associated with chemical reaction
    24% identity, 75% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory