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Searching for up to 100 curated homologs for CA265_RS12040 FitnessBrowser__Pedo557:CA265_RS12040 (386 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5a03C / Q9A8X3 Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose (see paper)
    43% identity, 88% coverage of query (302 bits)

5a05A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with maltotriose
    43% identity, 88% coverage of query (302 bits)

5a04A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glucose
    43% identity, 88% coverage of query (302 bits)

5a03E Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose
    43% identity, 88% coverage of query (302 bits)

5a02A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glycerol
    43% identity, 88% coverage of query (302 bits)

5a06A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with sorbitol
    43% identity, 88% coverage of query (302 bits)

gfo / Q07982 glucose-fructose oxidoreductase (EC 1.1.99.28) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
Q07982 glucose-fructose oxidoreductase (EC 1.1.99.28) from Zymomonas mobilis (see 4 papers)
    41% identity, 89% coverage of query (295 bits)

1h6dA / Q07982 Oxidized precursor form of glucose-fructose oxidoreductase from zymomonas mobilis complexed with glycerol (see paper)
    40% identity, 92% coverage of query (295 bits)

1rydA Crystal structure of glucose-fructose oxidoreductase from zymomonas mobilis
    40% identity, 92% coverage of query (295 bits)

1evjA Crystal structure of glucose-fructose oxidoreductase (gfor) delta1-22 s64d
    40% identity, 87% coverage of query (281 bits)

xacA / D4GP29 D-xylose dehydrogenase subunit (EC 1.1.1.424) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 4 papers)
XDH1_HALVD / D4GP29 D-xylose 1-dehydrogenase [NADP(+)] 1; XDH 1; EC 1.1.1.424 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 3 papers)
D4GP29 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) (EC 1.1.1.424) from Haloferax volcanii (see 2 papers)
    30% identity, 85% coverage of query (172 bits)

Build an alignment

Build an alignment for CA265_RS12040 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

D4GR07 L-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.376) from Haloferax volcanii (see paper)
    28% identity, 86% coverage of query (159 bits)

xdh / Q5UY95 D-xylose dehydrogenase subunit (EC 1.1.1.424) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see paper)
GFO6_HALMA / Q5UY95 D-xylose 1-dehydrogenase [NADP(+)]; XDH; EC 1.1.1.424 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) (see paper)
Q5UY95 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) (EC 1.1.1.424) from Haloarcula marismortui (see paper)
    27% identity, 87% coverage of query (146 bits)

XDH2_HALVD / D4GP30 D-xylose 1-dehydrogenase (NADP(+)) 2; XDH 2; EC 1.1.1.179 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP30 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179) from Haloferax volcanii (see paper)
    26% identity, 87% coverage of query (118 bits)

2glxA / Q2I8V6 Crystal structure analysis of bacterial 1,5-af reductase (see paper)
    25% identity, 87% coverage of query (107 bits)

afr / Q2I8V6 1,5-anhydro-D-fructose reductase (EC 1.1.1.292) from Ensifer adhaerens (see 3 papers)
AFR_ENSAD / Q2I8V6 1,5-anhydro-D-fructose reductase; Anhydrofructose reductase; 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming); EC 1.1.1.292 from Ensifer adhaerens (Sinorhizobium morelense) (see 2 papers)
Q2I8V6 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) from Ensifer adhaerens (see 2 papers)
    25% identity, 87% coverage of query (107 bits)

Q92KZ3 1,5-anhydro-D-fructose reductase (EC 1.1.1.263); 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) from Sinorhizobium meliloti (see paper)
4koaA / Q92KZ3 Crystal structure analysis of 1,5-anhydro-d-fructose reductase from sinorhizobium meliloti (see paper)
    26% identity, 87% coverage of query (103 bits)

7xr9A Crystal structure of dgpa with glucose
    28% identity, 75% coverage of query (99.0 bits)

7xreC / A0A3Q9WWX8 Crystal structure of dgpa
    29% identity, 70% coverage of query (97.1 bits)

dgpA / A0A3Q9WWX8 puerarin 3-dehydrogenase from human intestinal bacterium PUE (see 5 papers)
    28% identity, 72% coverage of query (96.7 bits)

KIJDR_ACTKI / B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; 3-ketoreductase; NADPH-dependent C3-ketoreductase; EC 1.1.1.384 from Actinomadura kijaniata (see paper)
B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Actinomadura kijaniata (see paper)
    22% identity, 85% coverage of query (96.3 bits)

3rc1A / B3TMR8 Crystal structure of kijd10, a 3-ketoreductase from actinomadura kijaniata incomplex with NADP and tdp-benzene (see paper)
    22% identity, 85% coverage of query (96.3 bits)

GRA26_STRVN / Q9ZA33 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; Gra-orf26 protein; dTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase; EC 1.1.1.384 from Streptomyces violaceoruber
    26% identity, 72% coverage of query (91.7 bits)

spnN / Q9ALN5 dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase (EC 1.1.1.384) from Saccharopolyspora spinosa (see paper)
SPNN_SACSN / Q9ALN5 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase; EC 1.1.1.384 from Saccharopolyspora spinosa (see 2 papers)
Q9ALN5 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Saccharopolyspora spinosa (see paper)
    22% identity, 86% coverage of query (85.5 bits)

3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
    21% identity, 86% coverage of query (82.0 bits)

3e18A / Q929L3 Crystal structure of NAD-binding protein from listeria innocua
    22% identity, 72% coverage of query (81.6 bits)

slgS4 / CBA11563.1 NDP-hexose-3-ketoreductase from Streptomyces lydicus (see paper)
    26% identity, 74% coverage of query (81.3 bits)

3q2kC / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    23% identity, 87% coverage of query (80.1 bits)

3q2iA / Q7NQL0 Crystal structure of the wlba dehydrognase from chromobactrium violaceum in complex with nadh and udp-glcnaca at 1.50 a resolution (see paper)
    24% identity, 89% coverage of query (75.9 bits)

1zh8A / Q9WYE8 Crystal structure of oxidoreductase (tm0312) from thermotoga maritima at 2.50 a resolution
    25% identity, 85% coverage of query (75.5 bits)

3q2kK / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    23% identity, 86% coverage of query (74.7 bits)

Q7NQL0 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase (EC 1.1.1.335) from Chromobacterium violaceum (see paper)
    24% identity, 89% coverage of query (73.9 bits)

mtmU / Q194Q3 D-oliose 4-ketoreductase from Streptomyces argillaceus (see paper)
    24% identity, 87% coverage of query (72.0 bits)

UGNO_METMP / Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase; UDP-GlcNAc oxidoreductase; UDP-N-acetyl-alpha-D-glucosamine:NAD(+) 3-oxidoreductase; EC 1.1.1.374 from Methanococcus maripaludis (strain S2 / LL) (see paper)
Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase (EC 1.1.1.374) from Methanococcus maripaludis (see paper)
    23% identity, 83% coverage of query (70.9 bits)

FPY6_FUSMA / A0A1L7U5T4 Dehydrogenase FPY6; Fusapyrone biosynthesis cluster protein 6; EC 1.1.1.- from Fusarium mangiferae (Mango malformation disease fungus)
    24% identity, 88% coverage of query (70.9 bits)

XDH_SCHPO / Q9UT60 Probable D-xylose 1-dehydrogenase (NADP(+)); XDH; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase homolog; NADP(+)-dependent D-xylose dehydrogenase; EC 1.1.1.179 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    21% identity, 73% coverage of query (69.7 bits)

iolX / P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (strain 168) (see paper)
IOLX_BACSU / P40332 scyllo-inositol 2-dehydrogenase (NAD(+)); EC 1.1.1.370 from Bacillus subtilis (strain 168) (see paper)
P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (see 2 papers)
    21% identity, 86% coverage of query (67.8 bits)

APSD_PARG4 / B1G894 D-apiose dehydrogenase; EC 1.1.1.420 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
    20% identity, 92% coverage of query (61.6 bits)

GFOD2_MOUSE / Q9CYH5 Glucose-fructose oxidoreductase domain-containing protein 2; EC 1.-.-.- from Mus musculus (Mouse) (see paper)
    20% identity, 86% coverage of query (54.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory