Searching for up to 100 curated homologs for CA265_RS14990 FitnessBrowser__Pedo557:CA265_RS14990 (480 a.a.)
Found high-coverage hits (≥70%) to 79 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YLAT1_RAT / Q9R0S5 Y+L amino acid transporter 1; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 from Rattus norvegicus (Rat) (see 2 papers)
TC 2.A.3.8.7 / Q9R0S5 y+LAT1 (transports neutral amino acids (i.e., Leu) in symport with Na+, Li+ or H+ in 1:1 stoichiometry; transports basic amino acids (i.e., Lys) by facilitated diffusion without a symported cation). Also transports the neurotoxicant, methylmercury-L-cysteine by molecular mimicry. Causes the Lysinuric protein intolerance condition in humans (Q9UM01) (Broer, 2008) (see 2 papers)
30% identity, 98% coverage of query (190 bits)
YLAT1_MOUSE / Q9Z1K8 Y+L amino acid transporter 1; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 from Mus musculus (Mouse) (see 3 papers)
30% identity, 98% coverage of query (188 bits)
YLAT1_HUMAN / Q9UM01 Y+L amino acid transporter 1; Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 from Homo sapiens (Human) (see 18 papers)
TC 2.A.3.8.22 / Q9UM01 Y+L amino acid transporter 1 (Monocyte amino acid permease 2) (MOP-2) (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1) from Homo sapiens (see 20 papers)
30% identity, 98% coverage of query (186 bits)
Build an alignment for CA265_RS14990 and 3 homologs with ≥ 30% identity
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6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
29% identity, 97% coverage of query (182 bits)
TC 2.A.3.8.29 / F1R8V8 Cationic amino acid transporter, y+LAT1 from Danio rerio
30% identity, 98% coverage of query (182 bits)
LAT2_RABIT / Q9N1Q4 Large neutral amino acids transporter small subunit 2; 4F2-LC5; L-type amino acid transporter 2; Solute carrier family 7 member 8 from Oryctolagus cuniculus (Rabbit) (see paper)
30% identity, 98% coverage of query (179 bits)
LAT2_MOUSE / Q9QXW9 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; mLAT2; Solute carrier family 7 member 8 from Mus musculus (Mouse) (see 6 papers)
30% identity, 96% coverage of query (178 bits)
LAT2_RAT / Q9WVR6 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; Solute carrier family 7 member 8 from Rattus norvegicus (Rat) (see 4 papers)
TC 2.A.3.8.6 / Q9WVR6 L-type neutral amino acid transporter, LAT2 (Na+-independent with broad specificity for all L-isomers of neutral amino acids; preferred substrate: Phe, His, Trp, Ile, Val, Leu, Gln, Cys, Ser; catalyzes obligatory exchange with μM affinities on the outside and mM affinities on the inside [1000x difference]). Both LAT2 and LAT1 (2.A.3.8.1) catalyze uptake of S-nitro-L-cysteine (Li and Whorton, 2005). Also transports thyroid hormones from Rattus norvegicus (Rat) (see 3 papers)
30% identity, 96% coverage of query (178 bits)
SLC7A8 / Q9UHI5 large neutral amino acids transporter small subunit 2 from Homo sapiens (see 4 papers)
LAT2_HUMAN / Q9UHI5 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8 from Homo sapiens (Human) (see 14 papers)
TC 2.A.3.8.20 / Q9UHI5 Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8). Certain detergents stabilize and allow purification of the 4F2hc-LAT2 complex, allowing the measurement of substrate binding. In addition, an improved 3D map could be obtained from Homo sapiens (see 12 papers)
30% identity, 96% coverage of query (178 bits)
SLC7A6 / Q92536 Y+L amino acid transporter 2 from Homo sapiens (see 3 papers)
YLAT2_HUMAN / Q92536 Y+L amino acid transporter 2; Cationic amino acid transporter, y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 from Homo sapiens (Human) (see 13 papers)
TC 2.A.3.8.23 / Q92536 Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2) from Homo sapiens (see 14 papers)
31% identity, 96% coverage of query (176 bits)
7b00A Human lat2-4f2hc complex in the apo-state
30% identity, 95% coverage of query (174 bits)
7cmhB / Q9UHI5 The lat2-4f2hc complex in complex with tryptophan (see paper)
30% identity, 95% coverage of query (173 bits)
7cmiB The lat2-4f2hc complex in complex with leucine
30% identity, 95% coverage of query (173 bits)
YLAT2_RAT / D3ZMM8 Y+L amino acid transporter 2; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 from Rattus norvegicus (Rat) (see 2 papers)
29% identity, 97% coverage of query (168 bits)
YLAT2_MOUSE / Q8BGK6 Y+L amino acid transporter 2; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 from Mus musculus (Mouse) (see 5 papers)
29% identity, 96% coverage of query (167 bits)
XCT_MOUSE / Q9WTR6 Cystine/glutamate transporter; Amino acid transport system xc-; Solute carrier family 7 member 11; Subtle gray protein; xCT from Mus musculus (Mouse) (see 8 papers)
TC 2.A.3.8.5 / Q9WTR6 Cystine/glutamate antiporter, xCT (requires the 4F2hc protein (TC #8.A.9.2.1)). Functions in the generation of glutathione and plays a role in the oxidative stress response from Mus musculus (Mouse) (see 3 papers)
26% identity, 98% coverage of query (162 bits)
BAT1_RABIT / Q9N1R6 b(0,+)-type amino acid transporter 1; b(0,+)AT; 4F2-LC6; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Oryctolagus cuniculus (Rabbit) (see paper)
25% identity, 98% coverage of query (162 bits)
STET_BACSU / O34739 Serine/threonine exchanger SteT from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.8.12 / O34739 The Ser/Thr exchange transporter (SteT) (also transports aromatic amino acids with lower efficiency) (Reig et al., 2007). The substrate-bound state of SteT shows increased conformational flexibility and kinetic stability, enabling transport of substrate across the cell membrane (Bippes et al. 2009). TMS8 sculpts the substrate-binding site and undergoes conformational changes during the transport cycle of SteT (Bartoccioni et al., 2010). Mutations allow substrate binding but not translocation. Other mutations stabilize the protein and result in higher production levels from Bacillus subtilis (see 2 papers)
28% identity, 99% coverage of query (160 bits)
BAT1_HUMAN / P82251 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Homo sapiens (Human) (see 16 papers)
TC 2.A.3.8.19 / P82251 B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) from Homo sapiens (see 9 papers)
25% identity, 99% coverage of query (160 bits)
BAT1_MOUSE / Q9QXA6 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Mus musculus (Mouse) (see 2 papers)
25% identity, 96% coverage of query (158 bits)
TC 2.A.3.8.2 / O13020 L-type neutral amino acid transporter, ASUR4 (Na+-independent) of 507 aas and 12 TMSs. Pregabalin (PGB), a drug for the treatment of epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder, may be transported by L-type transporters from Xenopus laevis (African clawed frog) (see 2 papers)
29% identity, 96% coverage of query (157 bits)
6li9B / P82251 Heteromeric amino acid transporter b0,+at-rbat complex bound with arginine (see paper)
25% identity, 96% coverage of query (156 bits)
TC 2.A.3.8.9 / Q19834 Heteromeric amino acid transporter #1 (transports most neutral aas with highest rates for Ala and Ser (Km≈100 μM)). They function by obligatory aa:aa exchange (Veljkovic et al., 2004b) (see paper)
27% identity, 96% coverage of query (156 bits)
AAA1_MOUSE / P63115 Asc-type amino acid transporter 1; Asc-1; D-serine transporter; Solute carrier family 7 member 10 from Mus musculus (Mouse) (see 5 papers)
AAA1_RAT / P63116 Asc-type amino acid transporter 1; Asc-1; D-serine transporter; Solute carrier family 7 member 10 from Rattus norvegicus (Rat) (see paper)
TC 2.A.3.8.13 / P63115 The Asc-type small neutral D- and L-amino acid:H+ symport transporter-1, Asc-1 (Slc7a10). Also transports amino acid related compounds. Heterodimeric; associates with 4F2hc (TC# 8.A.9.2.1) Most highly expressed in brain and lung, but to a lesser degree in placenta and small intestine. from Mus musculus (Mouse) (see 3 papers)
Slc7a10 Asc-type amino acid transporter 1 from Mus musculus (see paper)
26% identity, 90% coverage of query (155 bits)
7nf6B / A0A6P3EL78 Ovine b0,+at-rbat heterodimer (see paper)
25% identity, 96% coverage of query (154 bits)
TC 2.A.3.8.32 / D3DMK0 Large neutral amino acid transporter, CD98lc (LAT), of 442 aas from Drosophila melanogaster
31% identity, 88% coverage of query (151 bits)
BAT1_RAT / P82252 b(0,+)-type amino acid transporter 1; b(0,+)AT; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Rattus norvegicus (Rat) (see 2 papers)
TC 2.A.3.8.15 / P82252 The b0,+ amino acid (cystine) transporter associated with the cystinuria-related type II membrane glycoprotein, BAT1 which forms a heterodimer with rBAT (TC# 8.A.9.1.1). Present in the apical membrane of renal proximal tubules from Rattus norvegicus (Rat) (see 2 papers)
26% identity, 88% coverage of query (147 bits)
SLC7A11 / Q9UPY5 cystine/glutamate transporter from Homo sapiens (see paper)
XCT_HUMAN / Q9UPY5 Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT from Homo sapiens (Human) (see 9 papers)
TC 2.A.3.8.18 / Q9UPY5 Cystine/glutamate antiporter (Amino acid transport system xCT) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) from Homo sapiens (see 7 papers)
27% identity, 99% coverage of query (147 bits)
7p9uB / Q9UPY5 Cryo em structure of system xc- in complex with glutamate (see paper)
27% identity, 92% coverage of query (146 bits)
7epzB Overall structure of erastin-bound xct-4f2hc complex
27% identity, 92% coverage of query (146 bits)
TC 2.A.3.8.11 / Q50E62 The aromatic-preferring amino acid transporter (ArpAT or Slc7a15). Functions with rBAT or 4F2hc (8.A.9) and transports preferentially tyr and 3,4-dihydroxyphenylalanine (L-DOPA), but also ala, glu, ser, cys and arg by a Na+-independent mechanism (present in mouse, rat, dog and chicken, but silenced in humans and chimps)(Fernández et al., 2005; Sato et al., 2005) from Mus musculus (Mouse) (see 2 papers)
28% identity, 96% coverage of query (142 bits)
LAT1_RABIT / Q7YQK4 Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; L-type amino acid transporter 1; LAT1; Solute carrier family 7 member 5 from Oryctolagus cuniculus (Rabbit) (see 4 papers)
27% identity, 98% coverage of query (140 bits)
7dskB / Q01650 Overall structure of the lat1-4f2hc bound with jx-075 (see paper)
27% identity, 96% coverage of query (139 bits)
SLC7A5 / Q01650 large neutral amino acids transporter small subunit 1 from Homo sapiens (see 4 papers)
LAT1_HUMAN / Q01650 Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter from Homo sapiens (Human) (see 19 papers)
TC 2.A.3.8.25 / Q01650 Large neutral amino acids transporter small subunit 1 (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain; SLC3A2) (Integral membrane protein E16) (L-type amino acid transporter 1) (hLAT1) (Solute carrier family 7 member 5) (y+ system cationic and neutral amino acid transporter) from Homo sapiens (see 24 papers)
27% identity, 98% coverage of query (139 bits)
7dsqB Overall structure of the lat1-4f2hc bound with 3,5-diiodo-l-tyrosine
27% identity, 96% coverage of query (139 bits)
7dsnB Overall structure of the lat1-4f2hc bound with jx-119
27% identity, 96% coverage of query (139 bits)
7dslB Overall structure of the lat1-4f2hc bound with jx-078
27% identity, 96% coverage of query (139 bits)
LAT1_MOUSE / Q9Z127 Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; L-type amino acid transporter 1; LAT1; Solute carrier family 7 member 5 from Mus musculus (Mouse) (see 4 papers)
27% identity, 98% coverage of query (136 bits)
LAT1_RAT / Q63016 Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; Integral membrane protein E16; Protein TA1; L-type amino acid transporter 1; LAT-1; Solute carrier family 7 member 5 from Rattus norvegicus (Rat) (see 8 papers)
TC 2.A.3.8.1 / Q63016 L-type neutral amino acid transporter, LAT1 (Na+-independent) (prefers amino acids with branched or aromatic side chains: Phe, Ile, Leu, Val, Trp, His; catalyzes obligatory exchange with μM affinities on the outside and mM affinities on the inside [1000x difference]). Both LAT1 and LAT2 (2.A.3.8.6) catalyze uptake of S-nitroso-L-cysteine. These and other LAT family members are specifically inhibited by 2-aminobicyclo[2.2.1]heptane-2-carboxylic acid (Li and Whorton, 2005). Mediates tryptophan:kynurenine exchange (Kaper et al., 2007). Also transports thyroid hormones and their derivatives from Rattus norvegicus (Rat) (see 6 papers)
27% identity, 98% coverage of query (135 bits)
TC 2.A.3.8.3 / Q26594 The schistosome neutral and cationic amino acid transporter, SPRM1lc (Na+-independent), (takes up phe, arg, lys, ala, gln, his, trp and leu; functions with SPRM1hc (TC# 8.A.9.3.1) from Schistosoma mansoni (Blood fluke)
26% identity, 96% coverage of query (135 bits)
6irtB Human lat1-4f2hc complex bound with bch
27% identity, 95% coverage of query (134 bits)
AAA1_HUMAN / Q9NS82 Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10 from Homo sapiens (Human) (see paper)
TC 2.A.3.8.21 / Q9NS82 Asc-type amino acid transporter 1 (Asc-1) (Solute carrier family 7 member 10) from Homo sapiens (see 4 papers)
26% identity, 96% coverage of query (129 bits)
8qeyA / Q9NS82 Structure of human asc1/cd98hc heteromeric amino acid transporter (see paper)
26% identity, 90% coverage of query (128 bits)
6jmqA / Q01650 Lat1-cd98hc complex bound to mem-108 fab (see paper)
26% identity, 96% coverage of query (125 bits)
MTRTR_BACSU / Q797A7 Methylthioribose transporter from Bacillus subtilis (strain 168) (see paper)
26% identity, 98% coverage of query (120 bits)
YhfM / b3370 fructoselysine/psicoselysine transporter from Escherichia coli K-12 substr. MG1655 (see 4 papers)
frlA / P45539 fructoselysine/psicoselysine transporter from Escherichia coli (strain K12) (see 4 papers)
FRLA_ECOLI / P45539 Probable fructoselysine/psicoselysine transporter FrlA from Escherichia coli (strain K12) (see paper)
25% identity, 98% coverage of query (115 bits)
S7A13_MOUSE / Q91WN3 Solute carrier family 7 member 13; Sodium-independent aspartate/glutamate transporter 1; X-amino acid transporter 2 from Mus musculus (Mouse) (see 3 papers)
TC 2.A.3.8.8 / Q91WN3 Aspartate/glutamate Na+-independent transporter, AGT1 from Mus musculus (Mouse) (see 5 papers)
24% identity, 93% coverage of query (112 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
26% identity, 100% coverage of query (108 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
26% identity, 100% coverage of query (108 bits)
AAT6_CAEEL / Q22397 Amino acid transporter protein 6 from Caenorhabditis elegans (see 2 papers)
TC 2.A.3.8.27 / Q22397 Amino acid transporter 6 (AAT-6). Interacts with NRFL-1, the C. elegans NHERF orthologue to promote localization to the intestinal luminal membrane from Caenorhabditis elegans
23% identity, 93% coverage of query (104 bits)
CAAT4_ARATH / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.14 / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (see 4 papers)
26% identity, 87% coverage of query (101 bits)
TC 2.A.3.8.10 / Q9NA91 Aromatic amino acid exchanger, AAT-9 (Veljkovic et al., 2004b) from Caenorhabditis elegans (see paper)
22% identity, 98% coverage of query (93.6 bits)
ADIC_SALTY / P60066 Arginine/agmatine antiporter from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
23% identity, 77% coverage of query (89.7 bits)
TC 2.A.3.3.23 / S6EX81 Branched chain amino acid (Leucine/isoleucine/valine) uptake transporter of 469 aas and 12 TMSs, BcaP or CitA from Lactococcus lactis subsp. lactis A12
23% identity, 90% coverage of query (89.0 bits)
BCAP_LACLM / A2RHI9 Branched-chain amino acid permease BcaP; BCAA permease; BCAA transporter from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
23% identity, 99% coverage of query (88.6 bits)
CTR1_MOUSE / Q09143 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; ERR; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Mus musculus (Mouse) (see 7 papers)
TC 2.A.3.3.1 / Q09143 System Y+ high affinity basic amino acid transporter (CAT1) (ecotropic retrovival leukemia virus receptor (ERR)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 2 papers)
Slc7a1 / RF|NP_031539.3 high affinity cationic amino acid transporter 1 from Mus musculus
24% identity, 88% coverage of query (88.6 bits)
S7A12_MOUSE / Q8VIE6 Solute carrier family 7 member 12; Asc-type amino acid transporter 2; Asc-2; X-amino acid transporter 1; XAT-1 from Mus musculus (Mouse) (see 2 papers)
TC 2.A.3.8.14 / Q8VIE6 The Asc-type small neutral L-amino acid:H+ symport transporter-2 (Asc-2). Does not associate with 4F2hc or rBAT, but probably associates with some comparable heavy chain. Doesn't transport some substrates of Asc-1 such as α-aminoisobutyric acid and β-alanine from Mus musculus (Mouse) (see 2 papers)
Slc7a12 / RF|NP_543128.1 Asc-type amino acid transporter 2 from Mus musculus (see paper)
22% identity, 87% coverage of query (86.7 bits)
BCAP_BACSU / O07576 Branched-chain amino acid permease BcaP; BCAA permease from Bacillus subtilis (strain 168) (see 4 papers)
24% identity, 98% coverage of query (85.9 bits)
TC 2.A.3.8.16 / P38734 Low-affinity methionine permease, MUP3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
24% identity, 87% coverage of query (85.1 bits)
CTR1_HUMAN / P30825 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Homo sapiens (Human) (see 4 papers)
TC 2.A.3.3.9 / P30825 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homologue) (Ecotropic retrovirus receptor homologue) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) from Homo sapiens (see 6 papers)
23% identity, 88% coverage of query (82.8 bits)
5j4nA / P60061 Crystal structure of the l-arginine/agmatine antiporter adic in complex with agmatine at 2.6 angstroem resolution (see paper)
23% identity, 83% coverage of query (82.4 bits)
YjdD / b4115 arginine:agmatine antiporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
adiC / P60061 arginine:agmatine antiporter from Escherichia coli (strain K12) (see 2 papers)
ADIC_ECOLI / P60061 Arginine/agmatine antiporter from Escherichia coli (strain K12) (see 6 papers)
ADIC_ECO57 / P60063 Arginine/agmatine antiporter from Escherichia coli O157:H7 (see 3 papers)
TC 2.A.3.2.5 / P60061 Homodimeric electrogenic arginine (Km=80μM):agmatine antiporter, AdiC, involved in extreme acid resistance (Fang et al., 2007; Gong et al., 2003; Iyer et al., 2003). A projection structure at 6.5 Å resolution has been published (Casagrande et al., 2008), and the 3.2 Å resolution X-ray structure was determined by Fang et al., 2009 and Gao et al., 2009 from Escherichia coli (see 6 papers)
adiC / GB|AAN45533.1 arginine/agmatine antiporter from Shigella flexneri (see 6 papers)
23% identity, 83% coverage of query (82.4 bits)
YdgI / b1605 putative arginine:ornithine antiporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ARCD_ECOLI / P0AAE5 Putative arginine/ornithine antiporter from Escherichia coli (strain K12) (see paper)
23% identity, 86% coverage of query (80.9 bits)
CCNA_00435 L-proline transporter from Caulobacter crescentus NA1000
24% identity, 88% coverage of query (80.9 bits)
TC 2.A.3.5.1 / Q53148 Ethanolamine import permease from Rhodococcus erythropolis (see 2 papers)
28% identity, 80% coverage of query (80.9 bits)
CTR1_RAT / P30823 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Rattus norvegicus (Rat) (see paper)
22% identity, 88% coverage of query (80.1 bits)
TC 2.A.3.8.4 / P50276 L-methionine transporter, MUP1 from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
MUP1 / RF|NP_011569.1 high-affinity methionine permease from Saccharomyces cerevisiae
24% identity, 90% coverage of query (79.3 bits)
arcD / CAA04686.1 arginine /ornithine antiporter from Lactobacillus sakei (see 2 papers)
25% identity, 77% coverage of query (79.0 bits)
CadR / b2156 lysine:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 15 papers)
lysP / P25737 lysine:H+ symporter from Escherichia coli (strain K12) (see 13 papers)
LYSP_ECOLI / P25737 Lysine-specific permease LysP; Lysine transporter LysP; Trigger transporter LysP from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.2 / P25737 Lysine:H+ symporter. Forms a stable complex with CadC to allow lysine-dependent adaptation to acidic stress (Rauschmeier et al. 2013). The Salmonella orthologue is 95% identical to the E. coli protein and is highly specific for Lysine. Residues involved in lysine binding have been identified from Escherichia coli (see 5 papers)
lysP lysine-specific permease from Escherichia coli K12 (see 5 papers)
22% identity, 98% coverage of query (77.0 bits)
3l1lA Structure of arg-bound escherichia coli adic
21% identity, 82% coverage of query (75.9 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
24% identity, 91% coverage of query (73.2 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
22% identity, 99% coverage of query (69.7 bits)
CadB / b4132 lysine:cadaverine antiporter from Escherichia coli K-12 substr. MG1655 (see 10 papers)
CadB / P0AAE8 lysine:cadaverine antiporter from Escherichia coli (strain K12) (see 12 papers)
CADB_ECOLI / P0AAE8 Cadaverine/lysine antiporter from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.2.2 / P0AAE8 Cadaverine:lysine antiporter [Catalyzes cadaverine uptake via H+ symport (Km=21μM) and cadaverine export (Km=300 μM) via cadaverine:lysine antiport.] (Soksawatmaekhin et al., 2004). Modeling tools have been used to gain information about the structures and functions of CadB and PotE in E. coli from Escherichia coli (see 6 papers)
23% identity, 98% coverage of query (64.7 bits)
PotE / b0692 putrescine transporter PotE from Escherichia coli K-12 substr. MG1655 (see 13 papers)
potE / P0AAF1 putrescine transporter PotE from Escherichia coli (strain K12) (see 14 papers)
POTE_ECOLI / P0AAF1 Putrescine transporter PotE; Putrescine-proton symporter / putrescine-ornithine antiporter from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.3.2.1 / P0AAF1 Putrescine:ornithine antiporter for putrescine export; putrescine:H+ symporter for uptake from Escherichia coli (see 5 papers)
22% identity, 76% coverage of query (61.2 bits)
YjeH / b4141 L-methionine/branched chain amino acid exporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
yjeH / P39277 L-methionine/branched chain amino acid exporter from Escherichia coli (strain K12) (see 3 papers)
YJEH_ECOLI / P39277 L-methionine/branched-chain amino acid exporter YjeH from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.13.1 / P39277 The hydrophobic amino acid efflux transporter, YjeH from Escherichia coli (see 4 papers)
25% identity, 76% coverage of query (60.5 bits)
GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast) (see 8 papers)
GAP1 / RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
22% identity, 75% coverage of query (51.2 bits)
CAN1_YEAST / P04817 Arginine permease CAN1; Canavanine resistance protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
TC 2.A.3.10.4 / P04817 Arginine permease from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
CAN1 / RF|NP_010851.1 arginine permease from Saccharomyces cerevisiae
20% identity, 76% coverage of query (47.4 bits)
RMV1_ARATH / Q9FFL1 Polyamine transporter RMV1; Protein RESISTANT TO METHYL VIOLOGEN 1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.12.3 / Q9FFL1 Plasma membrane polyamine/paraquot uptake transporter of 490 aas, RMV1. Also called PUT3 and LAT1. Mutations give rise to partial paraquot (a toxic common herbicide that generates superoxide and reactive oxygen species (ROS)) from Arabidopsis thaliana
22% identity, 77% coverage of query (45.8 bits)
PheP / b0576 phenylalanine:H+ symporter PheP from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheP / P24207 phenylalanine:H+ symporter PheP from Escherichia coli (strain K12) (see 3 papers)
PHEP_ECOLI / P24207 Phenylalanine-specific permease; Phenylalanine:H(+) symporter PheP from Escherichia coli (strain K12) (see 6 papers)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli (see 6 papers)
20% identity, 93% coverage of query (44.3 bits)
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Lawrence Berkeley National Laboratory