Searching for up to 100 curated homologs for CA265_RS15000 FitnessBrowser__Pedo557:CA265_RS15000 (491 a.a.)
Found high-coverage hits (≥70%) to 69 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
43% identity, 99% coverage of query (370 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
43% identity, 99% coverage of query (370 bits)
BCAP_BACSU / O07576 Branched-chain amino acid permease BcaP; BCAA permease from Bacillus subtilis (strain 168) (see 4 papers)
44% identity, 99% coverage of query (340 bits)
MTRTR_BACSU / Q797A7 Methylthioribose transporter from Bacillus subtilis (strain 168) (see paper)
40% identity, 99% coverage of query (340 bits)
N515DRAFT_2924 L-proline transporter from Dyella japonica UNC79MFTsu3.2
44% identity, 98% coverage of query (340 bits)
CCNA_00435 L-proline transporter from Caulobacter crescentus NA1000
38% identity, 99% coverage of query (290 bits)
Ga0059261_1577 L-glutamine and L-histidine transporter from Sphingomonas koreensis DSMZ 15582
36% identity, 100% coverage of query (256 bits)
TC 2.A.3.3.23 / S6EX81 Branched chain amino acid (Leucine/isoleucine/valine) uptake transporter of 469 aas and 12 TMSs, BcaP or CitA from Lactococcus lactis subsp. lactis A12
33% identity, 100% coverage of query (245 bits)
BCAP_LACLM / A2RHI9 Branched-chain amino acid permease BcaP; BCAA permease; BCAA transporter from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
33% identity, 99% coverage of query (241 bits)
CAAT9_ARATH / Q9C5D6 Cationic amino acid transporter 9, chloroplastic from Arabidopsis thaliana (Mouse-ear cress) (see paper)
36% identity, 88% coverage of query (221 bits)
CAAT4_ARATH / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.14 / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (see 4 papers)
32% identity, 84% coverage of query (218 bits)
CAAT2_ARATH / Q9ASS7 Cationic amino acid transporter 2, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.13 / Q9ASS7 Cationic amino acid transporter 2, vacuolar from Arabidopsis thaliana (see 4 papers)
33% identity, 85% coverage of query (216 bits)
CTR2_HUMAN / P52569 Cationic amino acid transporter 2; CAT-2; CAT2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 from Homo sapiens (Human) (see 3 papers)
TC 2.A.3.3.8 / P52569 Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (Solute carrier family 7 member 2) from Homo sapiens (see 6 papers)
35% identity, 82% coverage of query (209 bits)
CTR1_RAT / P30823 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Rattus norvegicus (Rat) (see paper)
34% identity, 84% coverage of query (207 bits)
CTR1_MOUSE / Q09143 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; ERR; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Mus musculus (Mouse) (see 7 papers)
TC 2.A.3.3.1 / Q09143 System Y+ high affinity basic amino acid transporter (CAT1) (ecotropic retrovival leukemia virus receptor (ERR)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 2 papers)
Slc7a1 / RF|NP_031539.3 high affinity cationic amino acid transporter 1 from Mus musculus
33% identity, 84% coverage of query (206 bits)
CTR3_HUMAN / Q8WY07 Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3 from Homo sapiens (Human) (see paper)
TC 2.A.3.3.10 / Q8WY07 Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3) from Homo sapiens (see 5 papers)
34% identity, 87% coverage of query (205 bits)
CAAT1_ARATH / Q84MA5 Cationic amino acid transporter 1; Amino acid transporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
30% identity, 84% coverage of query (201 bits)
CTR2_MOUSE / P18581 Cationic amino acid transporter 2; CAT-2; CAT2; 20.5; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2; T-cell early activation protein; TEA from Mus musculus (Mouse) (see 6 papers)
33% identity, 84% coverage of query (199 bits)
CTR1_HUMAN / P30825 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Homo sapiens (Human) (see 4 papers)
TC 2.A.3.3.9 / P30825 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homologue) (Ecotropic retrovirus receptor homologue) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) from Homo sapiens (see 6 papers)
33% identity, 86% coverage of query (198 bits)
CAAT3_ARATH / Q8GYB4 Cationic amino acid transporter 3, mitochondrial from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 86% coverage of query (197 bits)
CTR2_CHICK / B3TP03 Cationic amino acid transporter 2; CAT-2; CAT2; cCAT-2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 from Gallus gallus (Chicken) (see paper)
33% identity, 85% coverage of query (197 bits)
TC 2.A.3.3.2 / P18581 Low affinity basic amino acid transporter (CAT2) (T-cell early activation protein (TEA)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 9 papers)
Slc7a2 / RF|NP_031540.2 low affinity cationic amino acid transporter 2 from Mus musculus (see paper)
33% identity, 84% coverage of query (196 bits)
CTR3_RAT / O08812 Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3 from Rattus norvegicus (Rat) (see paper)
33% identity, 87% coverage of query (193 bits)
Build an alignment for CA265_RS15000 and 23 homologs with ≥ 30% identity
Or download the sequences
CAAT5_ARATH / O64759 Cationic amino acid transporter 5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.12 / O64759 Cationic amino acid transporter 5 from Arabidopsis thaliana (see 3 papers)
29% identity, 86% coverage of query (189 bits)
CTR3_MOUSE / P70423 Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3 from Mus musculus (Mouse) (see paper)
TC 2.A.3.3.5 / P70423 The brain L-cationic (Arg, Lys, Orn, 2,4-diamino-n-butyrate) transporter, CAT3 (capacity of trans-stimulation by internal Arg) from Mus musculus (Mouse) (see 4 papers)
Slc7a3 / GI|123218479 Cationic amino acid transporter 3 from Mus musculus (see paper)
34% identity, 87% coverage of query (187 bits)
S7A14_DANRE / B0UYF2 Probable cationic amino acid transporter; Solute carrier family 7 member 14 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
32% identity, 85% coverage of query (185 bits)
CAAT6_ARATH / Q9LZ20 Cationic amino acid transporter 6, chloroplastic from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.4 / Q9LZ20 The amino acid transporter, CAT6. Mediates electrogenic transport of large neutral and cationic amino acids in preference to other amino acids. Present in lateral root primordia, flowers and seeds from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
T1E3_130 / GI|13430548 amino acid transport-like protein from Arabidopsis thaliana (see paper)
30% identity, 90% coverage of query (181 bits)
S7A14_HUMAN / Q8TBB6 Solute carrier family 7 member 14; Gamma-aminobutyric acid transporter SLC7A14 from Homo sapiens (Human) (see 2 papers)
31% identity, 87% coverage of query (181 bits)
S7A14_MOUSE / Q8BXR1 Solute carrier family 7 member 14; Gamma-aminobutyric acid transporter SLC7A14 from Mus musculus (Mouse) (see 2 papers)
31% identity, 87% coverage of query (179 bits)
Q16N01 ABC-type polar-amino-acid transporter (EC 7.4.2.1) from Aedes aegypti (see paper)
31% identity, 85% coverage of query (179 bits)
CAAT8_ARATH / Q9SHH0 Cationic amino acid transporter 8, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.11 / Q9SHH0 Cationic amino acid transporter 8, vacuolar from Arabidopsis thaliana (see 4 papers)
30% identity, 84% coverage of query (172 bits)
TC 2.A.3.3.24 / ALD51314.1 Plastidic cationic amino acid transporter, CAT, of 582 aas and 14 TMSs from Petunia x hybrida
31% identity, 83% coverage of query (145 bits)
BPHYT_RS17540 L-aspartate/L-glutamate/L-glutamine:H+ symporter from Burkholderia phytofirmans PsJN
26% identity, 90% coverage of query (113 bits)
AIMA_BACSU / Q45577 Glutamate/serine transporter AimA; Amino acid importer A from Bacillus subtilis (strain 168) (see 2 papers)
27% identity, 94% coverage of query (112 bits)
STET_BACSU / O34739 Serine/threonine exchanger SteT from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.8.12 / O34739 The Ser/Thr exchange transporter (SteT) (also transports aromatic amino acids with lower efficiency) (Reig et al., 2007). The substrate-bound state of SteT shows increased conformational flexibility and kinetic stability, enabling transport of substrate across the cell membrane (Bippes et al. 2009). TMS8 sculpts the substrate-binding site and undergoes conformational changes during the transport cycle of SteT (Bartoccioni et al., 2010). Mutations allow substrate binding but not translocation. Other mutations stabilize the protein and result in higher production levels from Bacillus subtilis (see 2 papers)
25% identity, 95% coverage of query (98.6 bits)
MmuP / b0260 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
mmuP / Q47689 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.10 / Q47689 S-Methylmethionine permease, MmuP from Escherichia coli (see 3 papers)
23% identity, 97% coverage of query (96.7 bits)
XCT_MOUSE / Q9WTR6 Cystine/glutamate transporter; Amino acid transport system xc-; Solute carrier family 7 member 11; Subtle gray protein; xCT from Mus musculus (Mouse) (see 8 papers)
TC 2.A.3.8.5 / Q9WTR6 Cystine/glutamate antiporter, xCT (requires the 4F2hc protein (TC #8.A.9.2.1)). Functions in the generation of glutathione and plays a role in the oxidative stress response from Mus musculus (Mouse) (see 3 papers)
28% identity, 90% coverage of query (95.9 bits)
6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
26% identity, 84% coverage of query (94.7 bits)
YLAT2_MOUSE / Q8BGK6 Y+L amino acid transporter 2; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 from Mus musculus (Mouse) (see 5 papers)
25% identity, 88% coverage of query (90.9 bits)
TC 2.A.3.8.3 / Q26594 The schistosome neutral and cationic amino acid transporter, SPRM1lc (Na+-independent), (takes up phe, arg, lys, ala, gln, his, trp and leu; functions with SPRM1hc (TC# 8.A.9.3.1) from Schistosoma mansoni (Blood fluke)
24% identity, 96% coverage of query (88.6 bits)
YLAT2_RAT / D3ZMM8 Y+L amino acid transporter 2; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 from Rattus norvegicus (Rat) (see 2 papers)
24% identity, 88% coverage of query (87.8 bits)
TC 2.A.3.8.9 / Q19834 Heteromeric amino acid transporter #1 (transports most neutral aas with highest rates for Ala and Ser (Km≈100 μM)). They function by obligatory aa:aa exchange (Veljkovic et al., 2004b) (see paper)
26% identity, 89% coverage of query (84.0 bits)
BAT1_RABIT / Q9N1R6 b(0,+)-type amino acid transporter 1; b(0,+)AT; 4F2-LC6; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Oryctolagus cuniculus (Rabbit) (see paper)
24% identity, 91% coverage of query (84.0 bits)
YcjJ / b1296 putrescine:H+ symporter PuuP from Escherichia coli K-12 substr. MG1655 (see 4 papers)
puuP / P76037 putrescine:H+ symporter PuuP from Escherichia coli (strain K12) (see 2 papers)
PUUP_ECOLI / P76037 Putrescine importer PuuP from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.3.1.13 / P76037 Putrescine importer, PuuP from Escherichia coli (strain K12) (see 4 papers)
23% identity, 94% coverage of query (82.8 bits)
puuP / BAD88704.1 putrescine importer, partial from Escherichia coli K-12 (see paper)
23% identity, 94% coverage of query (82.8 bits)
SLC7A5 / Q01650 large neutral amino acids transporter small subunit 1 from Homo sapiens (see 4 papers)
LAT1_HUMAN / Q01650 Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter from Homo sapiens (Human) (see 19 papers)
TC 2.A.3.8.25 / Q01650 Large neutral amino acids transporter small subunit 1 (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain; SLC3A2) (Integral membrane protein E16) (L-type amino acid transporter 1) (hLAT1) (Solute carrier family 7 member 5) (y+ system cationic and neutral amino acid transporter) from Homo sapiens (see 24 papers)
26% identity, 90% coverage of query (81.6 bits)
BAT1_MOUSE / Q9QXA6 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Mus musculus (Mouse) (see 2 papers)
24% identity, 84% coverage of query (81.6 bits)
TC 2.A.3.5.1 / Q53148 Ethanolamine import permease from Rhodococcus erythropolis (see 2 papers)
27% identity, 74% coverage of query (81.3 bits)
7dsqB Overall structure of the lat1-4f2hc bound with 3,5-diiodo-l-tyrosine
26% identity, 88% coverage of query (80.9 bits)
7dsnB Overall structure of the lat1-4f2hc bound with jx-119
26% identity, 88% coverage of query (80.9 bits)
7dslB Overall structure of the lat1-4f2hc bound with jx-078
26% identity, 88% coverage of query (80.9 bits)
7dskB / Q01650 Overall structure of the lat1-4f2hc bound with jx-075 (see paper)
26% identity, 88% coverage of query (80.9 bits)
BAT1_HUMAN / P82251 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Homo sapiens (Human) (see 16 papers)
TC 2.A.3.8.19 / P82251 B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) from Homo sapiens (see 9 papers)
24% identity, 97% coverage of query (80.5 bits)
6irtB Human lat1-4f2hc complex bound with bch
26% identity, 86% coverage of query (78.6 bits)
7p9uB / Q9UPY5 Cryo em structure of system xc- in complex with glutamate (see paper)
26% identity, 82% coverage of query (77.8 bits)
SLC7A11 / Q9UPY5 cystine/glutamate transporter from Homo sapiens (see paper)
XCT_HUMAN / Q9UPY5 Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT from Homo sapiens (Human) (see 9 papers)
TC 2.A.3.8.18 / Q9UPY5 Cystine/glutamate antiporter (Amino acid transport system xCT) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) from Homo sapiens (see 7 papers)
26% identity, 82% coverage of query (77.8 bits)
7epzB Overall structure of erastin-bound xct-4f2hc complex
26% identity, 82% coverage of query (77.4 bits)
6li9B / P82251 Heteromeric amino acid transporter b0,+at-rbat complex bound with arginine (see paper)
24% identity, 91% coverage of query (75.5 bits)
CAT1_SCHPO / Q9URZ4 Cationic amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
22% identity, 84% coverage of query (73.6 bits)
CadR / b2156 lysine:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 15 papers)
lysP / P25737 lysine:H+ symporter from Escherichia coli (strain K12) (see 13 papers)
LYSP_ECOLI / P25737 Lysine-specific permease LysP; Lysine transporter LysP; Trigger transporter LysP from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.2 / P25737 Lysine:H+ symporter. Forms a stable complex with CadC to allow lysine-dependent adaptation to acidic stress (Rauschmeier et al. 2013). The Salmonella orthologue is 95% identical to the E. coli protein and is highly specific for Lysine. Residues involved in lysine binding have been identified from Escherichia coli (see 5 papers)
lysP lysine-specific permease from Escherichia coli K12 (see 5 papers)
23% identity, 97% coverage of query (70.1 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
22% identity, 74% coverage of query (63.9 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
22% identity, 89% coverage of query (58.5 bits)
GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast) (see 8 papers)
GAP1 / RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
26% identity, 72% coverage of query (57.8 bits)
7nf6B / A0A6P3EL78 Ovine b0,+at-rbat heterodimer (see paper)
23% identity, 84% coverage of query (57.4 bits)
5j4nA / P60061 Crystal structure of the l-arginine/agmatine antiporter adic in complex with agmatine at 2.6 angstroem resolution (see paper)
21% identity, 79% coverage of query (56.6 bits)
YjdD / b4115 arginine:agmatine antiporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
adiC / P60061 arginine:agmatine antiporter from Escherichia coli (strain K12) (see 2 papers)
ADIC_ECOLI / P60061 Arginine/agmatine antiporter from Escherichia coli (strain K12) (see 6 papers)
ADIC_ECO57 / P60063 Arginine/agmatine antiporter from Escherichia coli O157:H7 (see 3 papers)
TC 2.A.3.2.5 / P60061 Homodimeric electrogenic arginine (Km=80μM):agmatine antiporter, AdiC, involved in extreme acid resistance (Fang et al., 2007; Gong et al., 2003; Iyer et al., 2003). A projection structure at 6.5 Å resolution has been published (Casagrande et al., 2008), and the 3.2 Å resolution X-ray structure was determined by Fang et al., 2009 and Gao et al., 2009 from Escherichia coli (see 6 papers)
adiC / GB|AAN45533.1 arginine/agmatine antiporter from Shigella flexneri (see 6 papers)
21% identity, 79% coverage of query (56.6 bits)
3l1lA Structure of arg-bound escherichia coli adic
21% identity, 79% coverage of query (52.8 bits)
AAT6_CAEEL / Q22397 Amino acid transporter protein 6 from Caenorhabditis elegans (see 2 papers)
TC 2.A.3.8.27 / Q22397 Amino acid transporter 6 (AAT-6). Interacts with NRFL-1, the C. elegans NHERF orthologue to promote localization to the intestinal luminal membrane from Caenorhabditis elegans
21% identity, 88% coverage of query (52.4 bits)
PheP / b0576 phenylalanine:H+ symporter PheP from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheP / P24207 phenylalanine:H+ symporter PheP from Escherichia coli (strain K12) (see 3 papers)
PHEP_ECOLI / P24207 Phenylalanine-specific permease; Phenylalanine:H(+) symporter PheP from Escherichia coli (strain K12) (see 6 papers)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli (see 6 papers)
21% identity, 90% coverage of query (46.6 bits)
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