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Searching for up to 100 curated homologs for CA265_RS15090 CA265_RS15090 NAD kinase (293 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7mh7A / Q9HZC0 Crystal structure of NAD kinase from pseudomonas aeruginosa pao1
    31% identity, 97% coverage of query (151 bits)

NADK_YERPE / Q8ZH09 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Yersinia pestis
    34% identity, 78% coverage of query (142 bits)

NADK_SALTY / P65774 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    30% identity, 97% coverage of query (140 bits)

NADK2_SYNY3 / P74430 NAD kinase 2; ATP-dependent NAD kinase 2; EC 2.7.1.23 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 4 papers)
P74430 NAD+ kinase (EC 2.7.1.23) from Synechocystis sp. (see 2 papers)
    34% identity, 74% coverage of query (139 bits)

YfjE / b2615 NAD kinase (EC 2.7.1.23) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
nadK / P0A7B3 NAD kinase from Escherichia coli (strain K12) (see 8 papers)
NADK_ECOLI / P0A7B3 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Escherichia coli (strain K12) (see 3 papers)
P0A7B3 NAD+ kinase (EC 2.7.1.23) from Archaeoglobus fulgidus (see paper)
ppnK / RF|NP_417105 probable inorganic polyphosphate/ATP-NAD kinase from Escherichia coli K12 (see paper)
    33% identity, 78% coverage of query (139 bits)

NADK_THEMA / Q9X255 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9X255 NAD+ kinase (EC 2.7.1.23) from Thermotoga maritima (see paper)
    36% identity, 76% coverage of query (135 bits)

Q6L7J5 NAD+ kinase (EC 2.7.1.23) from Sphingomonas sp. A1 (see paper)
    33% identity, 79% coverage of query (135 bits)

NADK_MYCTU / P9WHV7 NAD kinase; ATP-dependent NAD kinase; Poly(P)-dependent NAD kinase; PPNK; EC 2.7.1.23 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 5 papers)
P9WHV7 NAD+ kinase (EC 2.7.1.23) from Mycobacterium tuberculosis (see 4 papers)
    30% identity, 75% coverage of query (130 bits)

1y3iA / P9WHV7 Crystal structure of mycobacterium tuberculosis NAD kinase-NAD complex (see paper)
    30% identity, 73% coverage of query (126 bits)

Build an alignment

Build an alignment for CA265_RS15090 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q8VUL9 NAD+ kinase (EC 2.7.1.23) from Micrococcus luteus (see paper)
    29% identity, 76% coverage of query (124 bits)

NADK2_ARATH / Q9C5W3 NAD kinase 2, chloroplastic; AtNADK-2; EC 2.7.1.23 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9C5W3 NAD+ kinase (EC 2.7.1.23) from Arabidopsis thaliana (see 2 papers)
    30% identity, 92% coverage of query (120 bits)

A0A3Q7JHB9 NAD+ kinase (EC 2.7.1.23) from Solanum lycopersicum (see paper)
    31% identity, 80% coverage of query (118 bits)

K7LY64 NAD+ kinase (EC 2.7.1.23) from Glycine max (see paper)
    30% identity, 85% coverage of query (117 bits)

I1KAE3 NAD+ kinase (EC 2.7.1.23) from Glycine max (see paper)
    30% identity, 87% coverage of query (116 bits)

NADK1_SYNY3 / P73955 NAD kinase 1; ATP-dependent NAD kinase 1; EC 2.7.1.23 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P73955 NAD+ kinase (EC 2.7.1.23) from Synechocystis sp. (see 2 papers)
    31% identity, 76% coverage of query (108 bits)

UTR1 / P21373 NAD(+)/NADH kinase subunit from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 6 papers)
UTR1_YEAST / P21373 NAD(+) kinase; Unknown transcript 1 protein; EC 2.7.1.23 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P21373 NAD+ kinase (EC 2.7.1.23); NADH kinase (EC 2.7.1.86) from Strongylocentrotus purpuratus (see 2 papers)
    28% identity, 76% coverage of query (99.8 bits)

NADK_ARCFU / O30297 NAD kinase; ATP-dependent NAD kinase; EC 2.7.1.23 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
1suwA / O30297 Crystal structure of a NAD kinase from archaeoglobus fulgidus in complex with its substrate and product: insights into the catalysis of NAD kinase (see paper)
    27% identity, 81% coverage of query (96.3 bits)

1z0zA Crystal structure of a NAD kinase from archaeoglobus fulgidus in complex with NAD
    27% identity, 81% coverage of query (96.3 bits)

1z0sA Crystal structure of an NAD kinase from archaeoglobus fulgidus in complex with atp
    27% identity, 81% coverage of query (96.3 bits)

NADK_PYRHO / O58801 NAD kinase; ATP-dependent NAD kinase; Poly(P)-dependent NAD kinase; PPNK; EC 2.7.1.23 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
O58801 NAD+ kinase (EC 2.7.1.23) from Sphingomonas sp. (see paper)
    29% identity, 75% coverage of query (95.9 bits)

YJN2_SCHPO / Q9P7K3 Uncharacterized kinase C24B10.02c; EC 2.7.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    27% identity, 77% coverage of query (95.5 bits)

O13863 Uncharacterized kinase C1B1.02c; EC 2.7.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    27% identity, 78% coverage of query (90.5 bits)

C3RSF7 NAD+ kinase (EC 2.7.1.23) from Strongylocentrotus purpuratus (see paper)
    30% identity, 78% coverage of query (83.2 bits)

AN8837 mitochondrial NADH kinase (Eurofung) from Emericella nidulans (see paper)
    26% identity, 74% coverage of query (82.8 bits)

NADK / O95544 putative inorganic polyphosphate/ATP-NAD kinase from Homo sapiens (see 2 papers)
NADK_HUMAN / O95544 NAD kinase; Poly(P)/ATP NAD kinase; EC 2.7.1.23 from Homo sapiens (Human) (see paper)
O95544 NAD+ kinase (EC 2.7.1.23) from Homo sapiens (see 8 papers)
    28% identity, 77% coverage of query (79.3 bits)

O34934 NAD+ kinase (EC 2.7.1.23) from Bacillus subtilis (see paper)
    22% identity, 75% coverage of query (60.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory