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Searching for up to 100 curated homologs for CA265_RS18500 FitnessBrowser__Pedo557:CA265_RS18500 (355 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

Removed hits that are identical to the query, leaving 18

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Echvi_3851 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
    53% identity, 98% coverage of query (389 bits)

BT3549 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Bacteroides thetaiotaomicron VPI-5482
    51% identity, 98% coverage of query (374 bits)

Build an alignment

Build an alignment for CA265_RS18500 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

dapE / P44514 N-succinyl-L,L-diaminopimelate desuccinylase subunit (EC 3.5.1.18) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
DAPE_HAEIN / P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 7 papers)
P44514 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Haemophilus influenzae (see 3 papers)
    24% identity, 97% coverage of query (85.1 bits)

5vo3A / P44514 Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
    24% identity, 97% coverage of query (85.1 bits)

Q92Y75 acetylornithine deacetylase (EC 3.5.1.16) from Sinorhizobium meliloti (see paper)
    25% identity, 77% coverage of query (82.0 bits)

7uoiA / A0A1S8KJG1 Crystallographic structure of dape from enterococcus faecium
    24% identity, 95% coverage of query (79.0 bits)

MsgB / b2472 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
dapE / P0AED7 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Escherichia coli (strain K12) (see paper)
DAPE_ECOLI / P0AED7 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Escherichia coli (strain K12) (see paper)
dapE / RF|NP_416967 succinyl-diaminopimelate desuccinylase; EC 3.5.1.18 from Escherichia coli K12 (see 7 papers)
    24% identity, 72% coverage of query (75.1 bits)

7lgpB / P0AED8 Dape enzyme from shigella flexneri
    24% identity, 72% coverage of query (75.1 bits)

DAPE_SALTY / Q8ZN75 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; Aspartyl peptidase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    25% identity, 72% coverage of query (70.9 bits)

N515DRAFT_3767 N-acetylcitrulline deacetylase (EC 3.5.1.-) from Dyella japonica UNC79MFTsu3.2
    24% identity, 75% coverage of query (65.1 bits)

YgeY / b2872 putative peptidase YgeY from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    25% identity, 92% coverage of query (63.5 bits)

lysK / Q4JAP7 [amino group carrier protein]-lysine/ornithine hydrolase (EC 3.5.1.130; EC 3.5.1.132) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
    24% identity, 95% coverage of query (63.2 bits)

P9WHS9 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Mycobacterium tuberculosis (see 2 papers)
    25% identity, 95% coverage of query (62.8 bits)

ArgE / b3957 acetylornithine deacetylase (EC 3.5.1.16) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
argE / P23908 acetylornithine deacetylase (EC 3.5.1.16) from Escherichia coli (strain K12) (see 5 papers)
ARGE_ECOLI / P23908 Acetylornithine deacetylase; AO; Acetylornithinase; N-acetylornithinase; NAO; EC 3.5.1.16 from Escherichia coli (strain K12) (see 2 papers)
    25% identity, 76% coverage of query (61.6 bits)

7rsfA / P23908 Acetylornithine deacetylase from escherichia coli
    25% identity, 76% coverage of query (61.6 bits)

Q59284 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Corynebacterium glutamicum (see paper)
    25% identity, 74% coverage of query (55.1 bits)

DAPE_MYCS2 / A0R2G4 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    24% identity, 97% coverage of query (50.8 bits)

argE / CAB95019.1 acetylornithinase (n2-acetyl-l-ornithine amidohydrolase) from Moritella abyssi (see paper)
    21% identity, 91% coverage of query (48.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory