Searching for up to 100 curated homologs for CA265_RS19855 FitnessBrowser__Pedo557:CA265_RS19855 (479 a.a.)
Found high-coverage hits (≥70%) to 21 curated proteins.
Removed hits that are identical to the query, leaving 20
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BT4105 D-galacturonate transporter ExuT from Bacteroides thetaiotaomicron VPI-5482
62% identity, 99% coverage of query (577 bits)
Pf1N1B4_5129 D-galacturonate transporter ExuT from Pseudomonas fluorescens FW300-N1B4
53% identity, 99% coverage of query (474 bits)
Build an alignment for CA265_RS19855 and 2 homologs with ≥ 30% identity
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HSERO_RS23010 D-galacturonate transporter ExuT from Herbaspirillum seropedicae SmR1
27% identity, 87% coverage of query (160 bits)
TC 2.A.1.14.2 / P0AA78 Hexuronate (glucuronate; galacturonate) porter, ExuT (Nemoz et al. 1976). It also transports D-glucose (HJ Kim et al., Front. Microbiol., 23 January 2020) from Escherichia coli (see 3 papers)
28% identity, 99% coverage of query (157 bits)
ExuT / b3093 hexuronate transporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
exuT / P0AA78 hexuronate transporter from Escherichia coli (strain K12) (see 3 papers)
EXUT_ECOLI / P0AA78 Hexuronate transporter; Aldohexuronate transport system from Escherichia coli (strain K12) (see 5 papers)
28% identity, 99% coverage of query (157 bits)
TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
28% identity, 71% coverage of query (123 bits)
GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
28% identity, 71% coverage of query (122 bits)
YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
23% identity, 88% coverage of query (105 bits)
LgoT / b4356 galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lgoT / P39398 galactonate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
LGOT_ECOLI / P39398 Probable L-galactonate transporter; Galactonate:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
yjjL / RF|NP_418776 inner membrane transport protein yjjL from Escherichia coli K12 (see 2 papers)
24% identity, 82% coverage of query (105 bits)
6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
23% identity, 86% coverage of query (97.8 bits)
6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
23% identity, 87% coverage of query (87.0 bits)
ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
22% identity, 98% coverage of query (73.2 bits)
ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
20% identity, 98% coverage of query (67.0 bits)
NPT3_MOUSE / Q5SZA1 Sodium-dependent phosphate transport protein 3; Na(+)/PI cotransporter 3; Sodium/phosphate cotransporter 3; Solute carrier family 17 member 2 from Mus musculus (Mouse) (see paper)
22% identity, 75% coverage of query (55.5 bits)
S17A9_MOUSE / Q8VCL5 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Mus musculus (Mouse) (see 5 papers)
20% identity, 88% coverage of query (52.8 bits)
S17A9_RAT / P0DX21 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Rattus norvegicus (Rat) (see 2 papers)
20% identity, 88% coverage of query (52.4 bits)
TC 2.A.1.53.6 / I7I0I1 MFS uptake permease specific for pyrimidines, PhtC of 422 aas and 12 TMSs from Legionella pneumophila subsp. pneumophila
19% identity, 72% coverage of query (49.3 bits)
Q9SA71 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Arabidopsis thaliana (see paper)
22% identity, 80% coverage of query (48.5 bits)
S17A9_HUMAN / Q9BYT1 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Homo sapiens (Human) (see 4 papers)
TC 2.A.1.14.21 / Q9BYT1 The vesicular purine nucleotide (ADP, ATP, GTP) transporter, VNUT or SLC17A9. It is found in synaptic vesicles and chromafin granules (Sawada et al., 2008)) and is associated with disseminated superficial actinic porokeratosis (DSAP), a rare autosomal dominant genodermatosis (Cui et al. 2014). It plays a key role in purinergic signaling through its ability to transport nucleotides using the pmf. It catalyzes Cl--dependent transport activity involving essential arginines in the transmembrane region. Ketoacids inhibit these transporters through modulation of Cl- activation, but Cl- and the arginine residues are not important for ATP binding (Iwai et al. 2019). High expression of SLC17A9 correlates with a poor prognosis for colorectal cancer from Homo sapiens (Human) (see 5 papers)
19% identity, 84% coverage of query (48.5 bits)
NIAP_ACIAD / Q6FFF7 Niacin transporter NiaP from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
22% identity, 73% coverage of query (47.8 bits)
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Lawrence Berkeley National Laboratory