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Searching for up to 100 curated homologs for CA265_RS19865 FitnessBrowser__Pedo557:CA265_RS19865 (351 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

Removed hits that are identical to the query, leaving 29

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A0A0B6VMB0 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Flavobacterium sp. UMI-01 (see paper)
    37% identity, 95% coverage of query (220 bits)

2afbA / Q9WXS2 Crystal structure of 2-dehydro-3- deoxygluconokinase (ec 2.7.1.45) (tm0067) from thermotoga maritima at 2.05 a resolution (see paper)
    30% identity, 95% coverage of query (168 bits)

kdgK / Q9WXS2 2-keto-3-deoxygluconate kinase (EC 2.7.1.178) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WXS2 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Thermotoga maritima (see paper)
    30% identity, 95% coverage of query (166 bits)

Build an alignment

Build an alignment for CA265_RS19865 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

KDGK1_HALVD / D4GSE6 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxygluconate/2-keto-3-deoxygalactonate kinase; KDG kinase; KDGK-1; EC 2.7.1.178 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GSE6 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Haloferax volcanii (see paper)
    29% identity, 94% coverage of query (119 bits)

KDGK_THET8 / Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    27% identity, 88% coverage of query (90.1 bits)

1v1aA / Q53W83 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
    27% identity, 88% coverage of query (89.7 bits)

1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp
    27% identity, 88% coverage of query (89.7 bits)

3ktnA / Q837J7 Crystal structure of a putative 2-keto-3-deoxygluconate kinase from enterococcus faecalis
    25% identity, 94% coverage of query (80.9 bits)

Q0K080 dehydrogluconokinase (EC 2.7.1.13); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus necator (see paper)
    22% identity, 83% coverage of query (64.3 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    26% identity, 88% coverage of query (63.5 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    25% identity, 96% coverage of query (63.2 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    24% identity, 94% coverage of query (62.8 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    25% identity, 90% coverage of query (62.0 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    25% identity, 94% coverage of query (61.2 bits)

PS417_11850 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas simiae WCS417
    25% identity, 80% coverage of query (60.8 bits)

Pf6N2E2_512 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas fluorescens FW300-N2E2
    25% identity, 80% coverage of query (60.1 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    23% identity, 90% coverage of query (58.5 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 91% coverage of query (58.2 bits)

AO353_21335 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas fluorescens FW300-N2E3
    24% identity, 80% coverage of query (57.8 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    24% identity, 94% coverage of query (57.4 bits)

AO356_23160 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas fluorescens FW300-N2C3
    23% identity, 92% coverage of query (55.5 bits)

PGA1_c07240 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92) from Phaeobacter inhibens BS107
    24% identity, 89% coverage of query (55.5 bits)

CCNA_01356 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Caulobacter crescentus NA1000
iolC-DUF2090 / A0A0H3C6B4 bifunctional 5-dehydro-2-deoxygluconokinase/5-dehydro-2-deoxyphosphogluconate aldolase (EC 2.7.1.92; EC 4.1.2.29) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 3 papers)
    24% identity, 80% coverage of query (55.1 bits)

Q4KD57 2-ketogluconokinase (EC 2.7.1.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    24% identity, 96% coverage of query (54.7 bits)

3ih0A / O59128 Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
    24% identity, 84% coverage of query (53.9 bits)

3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
    24% identity, 84% coverage of query (53.5 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 88% coverage of query (52.4 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 96% coverage of query (50.8 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    24% identity, 96% coverage of query (49.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory