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Searching for up to 100 curated homologs for CA265_RS23280 FitnessBrowser__Pedo557:CA265_RS23280 (417 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

NanR / VIMSS3720738 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides vulgatus ATCC 8482
    32% identity, 95% coverage of query (209 bits)

NanR / VIMSS6110394 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides plebeius DSM 17135
    31% identity, 95% coverage of query (201 bits)

NanR / VIMSS6257414 NanR regulator of Sialic acid utilization; N-acetylglucosamine utilization, effector N-acetylglucosamine; N-acetylneuraminic acid (repressor) from Bacteroides eggerthii DSM 20697
    31% identity, 92% coverage of query (184 bits)

Build an alignment

Build an alignment for CA265_RS23280 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

XylR / VIMSS822024 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus clausii KSM-K16
    27% identity, 93% coverage of query (143 bits)

rokA / Q5GBH5 glucokinase / N-acetylglucosamine kinase / mannokinase (EC 2.7.1.7; EC 2.7.1.1; EC 2.7.1.59) from Bacteroides fragilis (see 2 papers)
    29% identity, 75% coverage of query (139 bits)

NagC / b0676 DNA-binding transcriptional dual regulator NagC from Escherichia coli K-12 substr. MG1655 (see 14 papers)
NAGC_ECOLI / P0AF20 N-acetylglucosamine repressor from Escherichia coli (strain K12) (see paper)
NagC / P0AF20 Transcription factor NagC (activator/repressor) from Escherichia coli K12 MG1655 (see 3 papers)
nagC / SP|P0AF20 N-acetylglucosamine repressor from Escherichia coli K12 (see paper)
    27% identity, 88% coverage of query (139 bits)

XylR / VIMSS38296 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus subtilis subsp. subtilis str. 168
    28% identity, 84% coverage of query (136 bits)

XylR / VIMSS6926953 XylR regulator of Xylose utilization, effector Xylose (repressor) from Paenibacillus sp. JDR-2
    27% identity, 89% coverage of query (136 bits)

1z05A / Q9KQJ1 Crystal structure of the rok family transcriptional regulator, homolog of e.Coli mlc protein.
    26% identity, 90% coverage of query (135 bits)

XylR / P16557 Transcription factor XylR (repressor) from Bacillus subtilis 168 (see 2 papers)
    26% identity, 94% coverage of query (134 bits)

NagC / VIMSS79758 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Pasteurella multocida subsp. multocida str. Pm70
    27% identity, 88% coverage of query (132 bits)

NagC / VIMSS4630820 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Moritella sp. PE36
    27% identity, 86% coverage of query (129 bits)

XylR / VIMSS279908 XylR regulator of Xylose utilization, effector Xylose (repressor) from Oceanobacillus iheyensis HTE831
    26% identity, 97% coverage of query (128 bits)

NagC / VIMSS548778 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Photorhabdus luminescens TTO1
    24% identity, 88% coverage of query (128 bits)

NagC / VIMSS339340 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (activator/repressor) from Vibrio parahaemolyticus RIMD 2210633
    25% identity, 88% coverage of query (127 bits)

NagC / VIMSS3566654 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Aeromonas salmonicida subsp. salmonicida A449
    24% identity, 88% coverage of query (127 bits)

XylR / VIMSS65339 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus halodurans C-125
    27% identity, 95% coverage of query (127 bits)

XylR / VIMSS854293 XylR regulator of Xylose utilization, effector Xylose (repressor) from Geobacillus kaustophilus HTA426
    23% identity, 94% coverage of query (125 bits)

Q8RDE9 glucokinase (EC 2.7.1.2) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
    29% identity, 74% coverage of query (125 bits)

NagC / VIMSS2773935 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Reinekea sp. MED297
    27% identity, 90% coverage of query (125 bits)

XylR / VIMSS3426742 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus pumilus SAFR-032
    26% identity, 94% coverage of query (121 bits)

XylR / VIMSS730014 XylR regulator of Xylose utilization, effector Xylose (repressor) from Bacillus licheniformis DSM 13
    23% identity, 96% coverage of query (118 bits)

glkA / CAA62003.1 glucokinase from Renibacterium salmoninarum (see 2 papers)
    28% identity, 74% coverage of query (117 bits)

XylR / P70928_BACLI Transcription factor XylR (repressor) from Bacillus licheniformis Gibson 46 (see paper)
    23% identity, 91% coverage of query (116 bits)

3vgkB / B1VZT1 Crystal structure of a rok family glucokinase from streptomyces griseus (see paper)
    27% identity, 74% coverage of query (112 bits)

B1VZT1 glucokinase (EC 2.7.1.2) from Streptomyces griseus (see 2 papers)
    27% identity, 74% coverage of query (112 bits)

3vglA Crystal structure of a rok family glucokinase from streptomyces griseus in complex with glucose and amppnp
    27% identity, 74% coverage of query (112 bits)

GLK_STRCO / P0A4E1 Glucokinase; Glucose kinase; ORF 3; EC 2.7.1.2 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
P0A4E1 glucokinase (EC 2.7.1.2) from Streptomyces coelicolor (see paper)
glkA glucokinase; EC 2.7.1.2 from Streptomyces coelicolor (see 2 papers)
    27% identity, 74% coverage of query (111 bits)

NagC / VIMSS1972937 NagC regulator of N-acetylglucosamine utilization, effector N-acetylglucosamine-6-phosphate (repressor) from Psychromonas ingrahamii 37
    26% identity, 86% coverage of query (111 bits)

O31392 glucokinase (EC 2.7.1.2) from Priestia megaterium (see paper)
glk glucokinase; EC 2.7.1.2 from Bacillus megaterium (see paper)
glk / CAA03848.1 glucose kinase from Bacillus megaterium (see paper)
    27% identity, 75% coverage of query (111 bits)

5f7qE / Q8YAF1 Rok repressor lmo0178 from listeria monocytogenes bound to operator (see paper)
    22% identity, 93% coverage of query (103 bits)

XylR / VIMSS354812 XylR regulator of Xylose utilization, effector Xylose (repressor) from Enterococcus faecalis V583
    23% identity, 92% coverage of query (101 bits)

XylR / VIMSS10362834 XylR regulator of Xylose utilization, effector Xylose; Glucose (repressor) from Thermotoga naphthophila RKU-10
    26% identity, 82% coverage of query (100 bits)

XylR / Q9WXW5_THEMA Transcription factor XylR (repressor) from Thermotoga maritima MSB8
    25% identity, 94% coverage of query (99.0 bits)

XylR / VIMSS1781991 XylR regulator of Xylose utilization, effector Xylose (repressor) from Mesorhizobium sp. BNC1
    24% identity, 83% coverage of query (99.0 bits)

XylR / VIMSS3676564 XylR regulator of Xylose utilization, effector Xylose; Glucose (repressor) from Thermotoga lettingae TMO
    24% identity, 94% coverage of query (90.1 bits)

IolR / VIMSS1300 IolR regulator of Inositol utilization (repressor) from Thermotoga maritima MSB8
    26% identity, 87% coverage of query (72.8 bits)

IolR / VIMSS5474541 IolR regulator of Inositol utilization (repressor) from Thermotoga neapolitana DSM 4359
    23% identity, 93% coverage of query (72.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory