Searching for up to 100 curated homologs for CCNA_00233 FitnessBrowser__Caulo:CCNA_00233 (345 a.a.)
Found high-coverage hits (≥70%) to 42 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pseB / O25511 UDP-N-acetylglucosamine 4,6-dehydratase subunit (EC 4.2.1.115) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 4 papers)
PSEB_HELPY / O25511 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see 3 papers)
59% identity, 96% coverage of query (408 bits)
2gn4A / O25511 Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADPH and udp-glcnac (see paper)
59% identity, 96% coverage of query (408 bits)
2gn8A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp
59% identity, 96% coverage of query (408 bits)
2gnaA Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-gal
59% identity, 96% coverage of query (408 bits)
2gn9A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glc
59% identity, 96% coverage of query (408 bits)
2gn6A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glcnac
59% identity, 96% coverage of query (408 bits)
Q6VYQ6 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Helicobacter pylori (see paper)
59% identity, 96% coverage of query (405 bits)
Q6VYQ5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Helicobacter pylori (see paper)
59% identity, 96% coverage of query (405 bits)
PSEB_CAMJJ / Q5QKR8 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) (see 2 papers)
57% identity, 96% coverage of query (400 bits)
PSEB_CAMJE / Q0P8W4 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
57% identity, 96% coverage of query (394 bits)
BC_3750 / Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.135) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see 5 papers)
Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Bacillus cereus (see 2 papers)
38% identity, 95% coverage of query (231 bits)
V5RBP5 UDP-glucose 4-epimerase (EC 5.1.3.2) from Acinetobacter baumannii (see paper)
40% identity, 96% coverage of query (230 bits)
CAPD_RICPR / Q9ZDJ5 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Rickettsia prowazekii (strain Madrid E) (see paper)
41% identity, 91% coverage of query (227 bits)
wbvB / Q8L348 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Vibrio cholerae O37 (see 3 papers)
39% identity, 95% coverage of query (223 bits)
3w1vA / A0A0H3JPH0 Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with inihibitor (see paper)
36% identity, 93% coverage of query (221 bits)
A0A0H3JPH0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Staphylococcus aureus (see paper)
37% identity, 92% coverage of query (221 bits)
wbjB / Q9KID0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see 2 papers)
39% identity, 94% coverage of query (221 bits)
4j2oC / P37362 Crystal structure of NADP-bound wbjb from a. Baumannii community strain d1279779 (see paper)
45% identity, 78% coverage of query (221 bits)
4g5hA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with by-product
36% identity, 93% coverage of query (220 bits)
3vvcA Crystal structure of capsular polysaccharide synthesizing enzyme cape , k126e, in apo form
37% identity, 93% coverage of query (211 bits)
6bwcC X-ray structure of pen from bacillus thuringiensis (see paper)
34% identity, 89% coverage of query (208 bits)
G5CSR9 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Megavirus chiliensis (see paper)
33% identity, 84% coverage of query (170 bits)
3vvbA / A0A0H3JPH0 Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in apo form (see paper)
32% identity, 92% coverage of query (166 bits)
4tqgA / G5CSR9 Crystal structure of megavirus udp-glcnac 4,6-dehydratase, 5-epimerase mg534 (see paper)
32% identity, 84% coverage of query (155 bits)
wbpM / Q9KIC5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Pseudomonas aeruginosa (see 6 papers)
33% identity, 80% coverage of query (155 bits)
EPSC_BACSU / P71052 Probable polysaccharide biosynthesis protein EpsC from Bacillus subtilis (strain 168) (see paper)
31% identity, 83% coverage of query (155 bits)
P72145 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see paper)
32% identity, 80% coverage of query (152 bits)
wbiI / GI|3135688 putative epimerase/dehydratase WbiI from Burkholderia pseudomallei (see paper)
36% identity, 80% coverage of query (152 bits)
wbgZ / Q9F736 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Shigella sonnei (see paper)
32% identity, 80% coverage of query (148 bits)
cpsE polysaccharide capsule synthesis protein CpsE from Streptococcus iniae (see paper)
35% identity, 78% coverage of query (144 bits)
wbkD / Q2YMM0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Brucella abortus (strain 2308) (see 2 papers)
32% identity, 77% coverage of query (134 bits)
Build an alignment for CCNA_00233 and 31 homologs with ≥ 30% identity
Or download the sequences
5bjuA / O86159 X-ray structure of the pglf dehydratase from campylobacter jejuni in complex with udp and NAD(h) (see paper)
29% identity, 82% coverage of query (129 bits)
pglF / Q0P9D4 UDP-N-acetylglucosamine C-6 dehydratase (EC 4.2.1.135) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 3 papers)
PGLF_CAMJE / Q0P9D4 UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase; UDP-GlcNAc C6 dehydratase; Protein glycosylation pathway protein F; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining); EC 4.2.1.135 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
29% identity, 82% coverage of query (128 bits)
5bjvA X-ray structure of the pglf udp-n-acetylglucosamine 4,6-dehydratase from campylobacterjejuni, d396n/k397a variant in complex with udp-n- acrtylglucosamine
29% identity, 82% coverage of query (125 bits)
RfbU / CAA69127.1 mannosyl-transferase from Vibrio cholerae (see paper)
30% identity, 80% coverage of query (124 bits)
3pvzA / Q5E8L1 Udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri
26% identity, 78% coverage of query (67.0 bits)
gdh / Q93EK0 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Saccharopolyspora spinosa (see 2 papers)
25% identity, 84% coverage of query (63.5 bits)
agl12 / D4GU72 dTDP-glucose-4,6-dehydratase (EC 4.2.1.46) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL12_HALVD / D4GU72 Low-salt glycan biosynthesis protein Agl12; EC 4.2.1.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
25% identity, 86% coverage of query (57.0 bits)
1kerB / Q8GIP9 The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with dtdp-d-glucose bound (see paper)
23% identity, 93% coverage of query (49.7 bits)
1ketA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with thymidine diphosphate bound
23% identity, 93% coverage of query (49.3 bits)
1kepA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with dtdp-xylose bound
23% identity, 93% coverage of query (49.3 bits)
6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
24% identity, 76% coverage of query (49.3 bits)
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Lawrence Berkeley National Laboratory