Searching for up to 100 curated homologs for CCNA_00397 FitnessBrowser__Caulo:CCNA_00397 (512 a.a.)
Found high-coverage hits (≥70%) to 56 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ILVX_MYCTU / O53554 Putative acetolactate synthase large subunit IlvX; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O53554 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
50% identity, 99% coverage of query (404 bits)
Build an alignment for CCNA_00397 and 1 homologs with ≥ 30% identity
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7orxCCC / Q0SCE8 jostii RHA1 thiamine diphosphate-dependent 4-hydroxybenzoylformate decarboxylase
28% identity, 97% coverage of query (130 bits)
bfd / CAK95977.1 benzoylformate decarboxylase from Pseudomonas putida (see paper)
27% identity, 97% coverage of query (125 bits)
bfd / CAK95976.1 benzoylformate decarboxylase from Pseudomonas putida (see paper)
27% identity, 98% coverage of query (124 bits)
6qsiA / Q4KB02 Pseudomonas fluorescens pf-5 thiamine diphosphate-dependent 4- hydroxybenzoylformate decarboxylase (see paper)
27% identity, 97% coverage of query (121 bits)
4q9dB / A0QSU7 X-ray structure of a putative thiamin diphosphate-dependent enzyme isolated from mycobacterium smegmatis (see paper)
26% identity, 98% coverage of query (119 bits)
6a50A Structure of benzoylformate decarboxylases in complex with cofactor tpp
26% identity, 98% coverage of query (119 bits)
mdlC / P20906 MdlC (EC 4.1.1.7) from Pseudomonas putida (see 2 papers)
P20906 benzoylformate decarboxylase (EC 4.1.1.7) from Pseudomonas putida (see 16 papers)
26% identity, 98% coverage of query (114 bits)
3fznA Intermediate analogue in benzoylformate decarboxylase
26% identity, 98% coverage of query (114 bits)
1bfdA Benzoylformate decarboxylase from pseudomonas putida
26% identity, 98% coverage of query (114 bits)
5deiA Benzoylformate decarboxylase from pseudomonas putida
26% identity, 98% coverage of query (114 bits)
3fsjX Crystal structure of benzoylformate decarboxylase in complex with the inhibitor mbp
26% identity, 98% coverage of query (114 bits)
1mczA Benzoylformate decarboxylase from pseudomonas putida complexed with an inhibitor, r-mandelate
26% identity, 98% coverage of query (114 bits)
dpgB / A3RJV5 benzoylformate decarboxylase monomer (EC 4.1.1.7) from Stutzerimonas stutzeri (see paper)
26% identity, 98% coverage of query (113 bits)
3f6bX Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor paa
26% identity, 98% coverage of query (113 bits)
1pi3A E28q mutant benzoylformate decarboxylase from pseudomonas putida
26% identity, 98% coverage of query (112 bits)
4k9qA / A4SXU0 The crystal structure of benzoylformate decarboxylase from polynucleobacter necessarius
27% identity, 96% coverage of query (102 bits)
Q5M4L0 acetolactate synthase (EC 2.2.1.6) from Streptococcus thermophilus (see paper)
24% identity, 99% coverage of query (100 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
24% identity, 99% coverage of query (95.9 bits)
1y9dD / P37063 Pyruvate oxidase variant v265a from lactobacillus plantarum (see paper)
26% identity, 99% coverage of query (94.7 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
25% identity, 99% coverage of query (92.4 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
24% identity, 100% coverage of query (91.3 bits)
Q836A5 acetolactate synthase (EC 2.2.1.6) from Enterococcus faecalis (see 2 papers)
23% identity, 99% coverage of query (90.1 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
24% identity, 99% coverage of query (89.7 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
22% identity, 98% coverage of query (89.0 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
25% identity, 99% coverage of query (89.0 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
25% identity, 99% coverage of query (89.0 bits)
P37063 pyruvate oxidase (EC 1.2.3.3) from Lactiplantibacillus plantarum (see 2 papers)
25% identity, 99% coverage of query (88.6 bits)
2ezuA Pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
25% identity, 99% coverage of query (87.8 bits)
2ez9A Pyruvate oxidase variant f479w in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
25% identity, 99% coverage of query (87.8 bits)
2ez8A Pyruvate oxidase variant f479w in complex with reaction intermediate 2-lactyl-thiamin diphosphate
25% identity, 99% coverage of query (87.8 bits)
2ez4B Pyruvate oxidase variant f479w
25% identity, 99% coverage of query (87.8 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
26% identity, 99% coverage of query (87.4 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
26% identity, 99% coverage of query (87.4 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
25% identity, 100% coverage of query (85.9 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
26% identity, 99% coverage of query (85.9 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
26% identity, 99% coverage of query (85.5 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
26% identity, 99% coverage of query (85.5 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
26% identity, 99% coverage of query (84.7 bits)
budB / P27696 catabolic acetolactate synthase (EC 2.2.1.6) from Klebsiella pneumoniae (see 2 papers)
25% identity, 99% coverage of query (84.7 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
23% identity, 100% coverage of query (83.2 bits)
als / Q7DAV2 α-acetolactate synthase subunit (EC 2.2.1.6) from Lactococcus lactis subsp. lactis (strain IL1403) (see 2 papers)
Q7DAV2 acetolactate synthase (EC 2.2.1.6) from Lactococcus lactis (see paper)
23% identity, 100% coverage of query (82.0 bits)
1ovmA / P23234 Crystal structure of indolepyruvate decarboxylase from enterobacter cloacae (see paper)
25% identity, 86% coverage of query (77.0 bits)
ipdC / P23234 indole-3-pyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter cloacae (see 2 papers)
DCIP_ENTCL / P23234 Indole-3-pyruvate decarboxylase; Indolepyruvate decarboxylase; EC 4.1.1.74 from Enterobacter cloacae (see paper)
P23234 indolepyruvate decarboxylase (EC 4.1.1.74) from Enterobacter cloacae (see paper)
24% identity, 86% coverage of query (76.6 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
24% identity, 98% coverage of query (75.9 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
25% identity, 85% coverage of query (75.9 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
25% identity, 99% coverage of query (75.5 bits)
4qq8C / Q9F4L3 Crystal structure of the formolase fls in space group p 43 21 2 (see paper)
25% identity, 100% coverage of query (70.9 bits)
3d7kA Crystal structure of benzaldehyde lyase in complex with the inhibitor mbp
25% identity, 100% coverage of query (69.7 bits)
3ey9A / P07003 Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from escherichia coli (see paper)
25% identity, 71% coverage of query (66.2 bits)
PoxB / b0871 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli K-12 substr. MG1655 (see 70 papers)
poxB / P07003 pyruvate oxidase (EC 1.2.5.1) from Escherichia coli (strain K12) (see 69 papers)
POXB_ECOLI / P07003 Pyruvate dehydrogenase [ubiquinone]; Pyruvate oxidase; POX; Pyruvate:ubiquinone-8 oxidoreductase; EC 1.2.5.1 from Escherichia coli (strain K12) (see 13 papers)
P07003 pyruvate dehydrogenase (quinone) (EC 1.2.5.1) from Escherichia coli (see paper)
25% identity, 71% coverage of query (65.9 bits)
Q92345 Probable pyruvate decarboxylase C1F8.07c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
23% identity, 85% coverage of query (62.8 bits)
6xn8A / A0A1H8YFL8 Crystal structure of 2-hydroxyacyl coa lyase (hacl) from rhodospirillales bacterium urhd0017
26% identity, 89% coverage of query (59.3 bits)
2vbiA / Q8L388 Holostructure of pyruvate decarboxylase from acetobacter pasteurianus
25% identity, 99% coverage of query (55.5 bits)
6vgsBBB / A0A0B8QZ66 6vgsBBB (see paper)
21% identity, 98% coverage of query (55.1 bits)
5npuA Inferred ancestral pyruvate decarboxylase (see paper)
24% identity, 85% coverage of query (51.2 bits)
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Lawrence Berkeley National Laboratory