Searching for up to 100 curated homologs for CCNA_00458 CCNA_00458 PTS system, N-acetylglucosamine-specific IIBC component (584 a.a.)
Found high-coverage hits (≥70%) to 24 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
AO356_17535 N-acetylglucosamine-specific PTS system, IIBC components (nagE) from Pseudomonas fluorescens FW300-N2C3
50% identity, 99% coverage of query (519 bits)
TC 4.A.1.1.15 / Q9HXN4 N-Acetyl-D-Glucosamine phosphotransferase system transporter, component of N-acetyl glucosamine-specific PTS permease, GlcNAc IIBC/GlcNAc I-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
50% identity, 99% coverage of query (499 bits)
BPHYT_RS02745 N-acetylglucosamine-specific PTS system, IIBC components (nagE) from Burkholderia phytofirmans PsJN
48% identity, 99% coverage of query (494 bits)
AO353_04465 N-acetylglucosamine-specific PTS system, IIBC components (nagE) from Pseudomonas fluorescens FW300-N2E3
46% identity, 99% coverage of query (470 bits)
PTWCB_BACSU / O34521 PTS system N-acetylglucosamine-specific EIICB component; EIICB-Nag; EC 2.7.1.193 from Bacillus subtilis (strain 168) (see 4 papers)
TC 4.A.1.1.7 / O34521 The N-acetylglucosamine IICB porter (NagP; YflF) (45% identical to 4.A.1.1.2) from Bacillus subtilis (see 2 papers)
45% identity, 84% coverage of query (377 bits)
PtsN / b0679 N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
nagE / P09323 N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191) from Escherichia coli (strain K12) (see 10 papers)
PTW3C_ECOLI / P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see 7 papers)
P09323 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193) from Escherichia coli (see 3 papers)
TC 4.A.1.1.2 / P09323 N-Acetyl glucosamine (NAG) porter (NagE) from Escherichia coli (see 6 papers)
45% identity, 84% coverage of query (368 bits)
PTG3C_BACSU / P20166 PTS system glucose-specific EIICBA component; EII-Glc/EIII-Glc; EIICBA-Glc; EIICBA-Glc 1; EC 2.7.1.199 from Bacillus subtilis (strain 168) (see 2 papers)
TC 4.A.1.1.9 / P20166 The glucose IICBA porter (PtsG) 44% identical to 4.A.1.1.1) from Bacillus subtilis (see 8 papers)
ptsG / GB|CAB13262.1 PTS system glucose-specific EIICBA component; EC 2.7.1.-; EC 2.7.1.69 from Bacillus subtilis (see 8 papers)
ptsG / CAA77803.1 IIGlc from Bacillus subtilis (see 3 papers)
41% identity, 87% coverage of query (367 bits)
PTW3C_BACSU / P39816 PTS system glucosamine-specific EIICBA component; EC 2.7.1.- from Bacillus subtilis (strain 168) (see 4 papers)
TC 4.A.1.1.6 / P39816 The glucosamine IICBA porter (GamP) (40% identical to 4.A.1.1.2) (Plumbridge 2015). The IIA domain in this protein can transfer the phosphoryl moiety to the maltose, N-acetylglucosamine, sucrose and trehalose PTS systems (MalP, NagP, SacP and TreP, respectively) from Bacillus subtilis (see 3 papers)
42% identity, 87% coverage of query (362 bits)
P45604 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193) from Klebsiella pneumoniae (see paper)
44% identity, 84% coverage of query (362 bits)
PTU3C_STACT / Q53922 PTS system glucoside-specific EIICBA component; EIICBA-Glc 2; EC 2.7.1.- from Staphylococcus carnosus (strain TM300) (see 2 papers)
TC 4.A.1.1.14 / Q53922 Glucose porter GlcB (IICBA). Glucose uptake is inhibited by methyl-α-D-glucoside, methyl-β-D-glucoside, p-nitrophenyl-α-D-glucoside, o-nitrophenyl-β-D-glucoside and salicin, but not by 2-deoxyglucose. Mannose and N-acetylglucosamine are not transported from Staphylococcus carnosus (strain TM300) (see 4 papers)
37% identity, 88% coverage of query (327 bits)
PTG3C_STACT / Q57071 PTS system glucose-specific EIICBA component; EIICBA-Glc; EII-Glc; EIICBA-Glc 1; EC 2.7.1.199 from Staphylococcus carnosus (strain TM300) (see 2 papers)
TC 4.A.1.1.13 / Q57071 Glucose porter, GlcA (IICBA). Glucose uptake is inhibited by 2-deoxyglucose and methyl-β-D-glucoside from Staphylococcus carnosus (strain TM300) (see 4 papers)
40% identity, 88% coverage of query (324 bits)
PtsG / b1101 glucose-specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli K-12 substr. MG1655 (see 29 papers)
ptsG / P69786 glucose-specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli (strain K12) (see 26 papers)
PTGCB_ECOLI / P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12) (see 13 papers)
P69786 protein-Npi-phosphohistidine-D-glucose phosphotransferase (EC 2.7.1.199) from Escherichia coli (see 3 papers)
TC 4.A.1.1.1 / P69786 PTS system glucose-specific EIICB component PTGB aka PTSG aka GLCA aka UMG aka B1101, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside) from Escherichia coli (see 11 papers)
ptsG / MB|P69786 PTS system glucose-specific EIICB component; EC 2.7.1.69 from Escherichia coli K12 (see 10 papers)
40% identity, 83% coverage of query (317 bits)
PTGCB_SALTY / P37439 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
39% identity, 83% coverage of query (315 bits)
MalX / b1621 PTS enzyme IIBC component MalX from Escherichia coli K-12 substr. MG1655 (see 5 papers)
MalX / P19642 PTS enzyme IIBC component MalX from Escherichia coli (strain K12) (see 4 papers)
PTOCB_ECOLI / P19642 PTS system maltose-specific EIICB component; EC 2.7.1.208 from Escherichia coli (strain K12) (see 2 papers)
TC 4.A.1.1.3 / P19642 Maltose porter (MalX) from Escherichia coli (see 6 papers)
malX / RF|NP_416138.1 PTS system maltose- and glucose-specific EIICB component; EC 2.7.1.69 from Escherichia coli K12 (see paper)
38% identity, 84% coverage of query (278 bits)
TC 4.A.1.1.18 / O51590 Glucose-specific Enzyme IIBC of the PTS, PtsG from Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
35% identity, 85% coverage of query (272 bits)
PTUCB_KLEPN / Q9AGA7 PTS system alpha-glucoside-specific EIICB component; EC 2.7.1.- from Klebsiella pneumoniae (see paper)
TC 4.A.1.1.10 / Q9AGA7 The α-glucoside-specific IICB, AglB (transports glucose, methyl-α-glucoside, maltitol, isomaltose, trehalulose α(1→1), turanose α(1→3), maltulose α(1→4), leucrose α(1→5), and palatinose α(1→6), but not sucrose (most resembles 4.A.1.1.4 and 4.A.1.1.8) (see 2 papers)
34% identity, 81% coverage of query (207 bits)
TC 4.A.1.1.17 / Q63GK8 The Maltose group translocator, MalT of 470 aas and 10 TMSs. Takes up extracellular maltose, releasing maltose-phosphate into the cytoplasm from Bacillus cereus (strain ZK / E33L)
32% identity, 84% coverage of query (205 bits)
TC 4.A.1.1.4 / O06900 The α-glucoside-specific IICB (MalB) (substrates probably include glucosyl-α-fructose disaccharides: trehalurose (α-1,1), turanose (α-1,3), malturose (α-1,4), leucrose (α-1,5) and palatinose (α-1,6)) from Fusobacterium mortiferum (see 2 papers)
33% identity, 81% coverage of query (199 bits)
PTUCB_LEPBD / C7NB69 PTS system alpha-glucoside-specific EIICB component; EC 2.7.1.- from Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b) (see paper)
TC 4.A.1.1.16 / C7NB69 PTS uptake porter for sucrose isomers, IICB from Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249)
33% identity, 72% coverage of query (197 bits)
PTOCB_BACSU / P54715 PTS system maltose-specific EIICB component; EC 2.7.1.208 from Bacillus subtilis (strain 168) (see 2 papers)
TC 4.A.1.1.8 / P54715 The maltose IICB porter (MalP; GlvC) (56% identical to 4.A.1.1.4) from Bacillus subtilis (see 3 papers)
30% identity, 81% coverage of query (196 bits)
Q93Q02 protein-Npi-phosphohistidine-maltose phosphotransferase (EC 2.7.1.208) from Clostridium acetobutylicum (see paper)
30% identity, 81% coverage of query (180 bits)
Build an alignment for CCNA_00458 and 21 homologs with ≥ 30% identity
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TC 4.A.1.1.11 / Q8DS05 The maltose/maltotriose porter, MalT (31% identical to 4.A.1.1.9) from Streptococcus mutans (see paper)
28% identity, 86% coverage of query (179 bits)
TC 4.A.1.1.19 / ART98514 PTS α-glucoside transporter, subunit IICB from Lactobacillus gasseri
27% identity, 99% coverage of query (174 bits)
TC 4.A.1.1.12 / Q48WG5 Maltose/Maltotriose PTS transporter, MalT (Shelburne et al., 2008) 631aas (68% identical to 4.A.1.1.11 from S. mutans from Streptococcus pyogenes serotype M1 (see paper)
27% identity, 72% coverage of query (144 bits)
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Lawrence Berkeley National Laboratory