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Searching for up to 100 curated homologs for CCNA_01335 FitnessBrowser__Caulo:CCNA_01335 (305 a.a.)

Found high-coverage hits (≥70%) to 94 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.131.1 / P42332 BcrA, component of The 2 or 3 component bacitracin-resistance efflex pump, BcrAB or BcrABC (Podlesek et al., 1995; Bernard et al., 2003) (BcrA is most similar to SpaF (3.A.1.124.2), but BcrB (5-6 TMSs) is only distantly related to other ABC2-type membrane proteins (Wang et al., 2009). BcrC is not sufficiently similar to detect similarity in BLAST searches. BcrC (5TMSs) belongs to the PAP2 phosphatase superfamily and may not be a contituent of the BcrAB transporter. Transcription is regulated by BcrR, a one-component transmembrane signal transduction system from Bacillus licheniformis (see paper)
bcrA / GB|AAA99504.1 bacitracin ABC transporter, ATP-binding protein BcrA from Bacillus licheniformis (see paper)
    35% identity, 96% coverage of query (185 bits)

TC 3.A.1.124.3 / Q75V15 NukF, component of The lantibiotic Nukacin ISK-1 (TC# 1.C.21.1.5)/NukH (BAD01013; 92aas) exporter, NukEFG from Staphylococcus warneri (see paper)
    35% identity, 92% coverage of query (184 bits)

TC 3.A.1.124.5 / Q09II0 SboF, component of The salivaricin exporter, SboEFG from Streptococcus salivarius (see paper)
    34% identity, 95% coverage of query (179 bits)

BCRA_ENTFL / Q5WNX0 Bacitracin transport ATP-binding protein BcrA from Enterococcus faecalis (Streptococcus faecalis) (see 2 papers)
    40% identity, 71% coverage of query (173 bits)

TC 3.A.1.124.4 / A6MER5 McdF, component of The macedocin exporter, McdEFG from Streptococcus macedonicus (see paper)
    40% identity, 72% coverage of query (169 bits)

TC 3.A.1.124.2 / Q45404 SpaF, component of The 3-component subtilin immunity exporter, SpaEFG from Bacillus subtilis (see paper)
    41% identity, 70% coverage of query (164 bits)

NOSF_STUST / P19844 Probable ABC transporter ATP-binding protein NosF from Stutzerimonas stutzeri (Pseudomonas stutzeri) (see 2 papers)
nosF / CAA37716.1 NosF ATPase from Pseudomonas stutzeri (see 13 papers)
    40% identity, 71% coverage of query (152 bits)

7o12B / P19844 Abc transporter nosdfy, amppnp-bound in gdn (see paper)
    40% identity, 71% coverage of query (152 bits)

7o17B Abc transporter nosdfy e154q, atp-bound in lipid nanodisc
    40% identity, 71% coverage of query (150 bits)

TC 3.A.1.132.2 / Q52900 NosF, component of The NosDFY Copper ABC transporter from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
nosF / AAC44025.1 NosF protein from Sinorhizobium meliloti (see paper)
    40% identity, 71% coverage of query (148 bits)

YhiG / b3486 ribosome-associated ATPase from Escherichia coli K-12 substr. MG1655 (see 13 papers)
RBBA_ECOLI / P37624 Ribosome-associated ATPase; Ribosomal bound ATPase from Escherichia coli (strain K12) (see 5 papers)
yhiH / RF|YP_026225 uncharacterized ABC transporter ATP-binding protein yhiH from Escherichia coli K12 (see paper)
    36% identity, 82% coverage of query (148 bits)

DRRA_STRPE / P32010 Daunorubicin/doxorubicin resistance ATP-binding protein DrrA; EC 7.6.2.- from Streptomyces peucetius (see 2 papers)
P32010 ABC-type xenobiotic transporter (EC 7.6.2.2) from Streptomyces peucetius (see paper)
TC 3.A.1.105.1 / P32010 DrrA, component of Daunorubicin, doxorubicin etc. (multidrug resistance) exporter, DrrAB from Streptomyces peucetius (see 2 papers)
    37% identity, 74% coverage of query (139 bits)

YXLF_BACSU / P94374 Uncharacterized ABC transporter ATP-binding protein YxlF; EC 7.-.-.- from Bacillus subtilis (strain 168) (see paper)
    31% identity, 92% coverage of query (139 bits)

LNRL_BACSU / P94440 Linearmycin resistance ATP-binding protein LnrL; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 2 papers)
    33% identity, 95% coverage of query (138 bits)

sagG / GI|23305059 ABC transporter, ATP-binding protein SagG from Streptococcus iniae (see paper)
    31% identity, 95% coverage of query (136 bits)

TC 3.A.1.132.1 / O30489 GldA, component of The GldAFG putative ABC transporter required for ratchet-type gliding motility; may function in secretion of a macromolecule such as an exopolysaccharide. (Agarwal et al., 1997; Hunnicutt et al., 2002; McBride and Zhu 2013). Soluble GldG homologues (no TMSs) are found in eukaryotes (e.g. intraflagellar protein transporter, IPT52 of Chlamydomonas reinhardtii; XP_001692161) from Cytophaga johnsonae (Flavobacterium johnsoniae) (see paper)
    31% identity, 94% coverage of query (134 bits)

TC 3.A.1.4.5 / Q8NRV7 UrtE, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    38% identity, 70% coverage of query (131 bits)

YbhF / b0794 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
ybhF / P0A9U1 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli (strain K12) (see 6 papers)
YBHF_ECOLI / P0A9U1 Probable multidrug ABC transporter ATP-binding protein YbhF from Escherichia coli (strain K12) (see paper)
ybhF / MB|P0A9U1 uncharacterized ABC transporter ATP-binding protein ybhF from Escherichia coli K12 (see paper)
    36% identity, 72% coverage of query (131 bits)

MEATP_MYCTU / O86311 Multidrug efflux system ATP-binding protein Rv1218c; EC 7.6.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
    33% identity, 100% coverage of query (128 bits)

TC 3.A.1.105.2 / Q53716 OleC4, component of Oleandomycin (drug resistance) exporter from Streptomyces antibioticus (see paper)
    37% identity, 73% coverage of query (127 bits)

FLQE1_MYCTU / P9WQL7 Fluoroquinolones export ATP-binding protein Rv2688c; EC 7.6.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    32% identity, 92% coverage of query (126 bits)

CED7_CAEEL / P34358 ABC transporter ced-7; Cell death protein 7 from Caenorhabditis elegans (see paper)
TC 3.A.1.211.4 / P34358 The aced cell death 7 (ced-7) protein (translocates molecules that mediate adhesion between dying and engulfing embryonic cells during programmed death) from Caenorhabditis elegans (see 4 papers)
ced-7 / RF|NP_001021226.1 ABC transporter ced-7 from Caenorhabditis elegans
    35% identity, 71% coverage of query (125 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    35% identity, 78% coverage of query (118 bits)

ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
    33% identity, 70% coverage of query (110 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    31% identity, 72% coverage of query (105 bits)

Build an alignment

Build an alignment for CCNA_01335 and 25 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

6xjiC / X5EJW5 Pmtcd abc exporter at c1 symmetry (see paper)
    24% identity, 92% coverage of query (105 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    32% identity, 70% coverage of query (102 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    32% identity, 70% coverage of query (102 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    32% identity, 70% coverage of query (102 bits)

6b89A E. Coli lptb in complex with adp and novobiocin
    28% identity, 73% coverage of query (100 bits)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
    28% identity, 73% coverage of query (100 bits)

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
    28% identity, 73% coverage of query (100 bits)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
    28% identity, 73% coverage of query (100 bits)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
    28% identity, 73% coverage of query (100 bits)

6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
    28% identity, 74% coverage of query (99.8 bits)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
    28% identity, 71% coverage of query (99.4 bits)

6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
    27% identity, 71% coverage of query (97.1 bits)

7lkzA Structure of atp-bound human abca4
    31% identity, 79% coverage of query (95.9 bits)

ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
    29% identity, 75% coverage of query (95.5 bits)

1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
    27% identity, 74% coverage of query (94.7 bits)

ABCA2_HUMAN / Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see 10 papers)
    33% identity, 83% coverage of query (94.4 bits)

7m1qA / P78363 Human abca4 structure in complex with n-ret-pe (see paper)
    30% identity, 86% coverage of query (94.4 bits)

1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
    27% identity, 74% coverage of query (94.0 bits)

TGD3_ARATH / Q9AT00 Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic; ABC transporter I family member 13; ABC transporter ABCI.13; AtABCI13; Non-intrinsic ABC protein 11; AtNAP11 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.27.2 / Q9AT00 Tdg3, component of The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
    27% identity, 81% coverage of query (93.2 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    29% identity, 83% coverage of query (92.0 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    29% identity, 83% coverage of query (92.0 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    29% identity, 71% coverage of query (86.7 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    29% identity, 71% coverage of query (86.7 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    29% identity, 71% coverage of query (86.7 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    29% identity, 71% coverage of query (86.7 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    29% identity, 71% coverage of query (86.7 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    29% identity, 71% coverage of query (86.7 bits)

ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
    32% identity, 70% coverage of query (85.5 bits)

ABCG5_MOUSE / Q99PE8 ATP-binding cassette sub-family G member 5; Sterolin-1; EC 7.6.2.- from Mus musculus (Mouse) (see 15 papers)
    26% identity, 91% coverage of query (84.3 bits)

8hprC Lpqy-sugabc in state 4
    29% identity, 70% coverage of query (83.6 bits)

8hprD Lpqy-sugabc in state 4
    29% identity, 70% coverage of query (83.2 bits)

ABCG1_HUMAN / P45844 ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog; EC 7.6.2.- from Homo sapiens (Human) (see 11 papers)
TC 3.A.1.204.12 / P45844 The intracellular sterol transporter, ABCG1 from Homo sapiens (see 13 papers)
    29% identity, 72% coverage of query (82.4 bits)

ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    31% identity, 72% coverage of query (81.6 bits)

P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
    29% identity, 72% coverage of query (81.3 bits)

7r8eA / P45844 The structure of human abcg1 e242q complexed with atp (see paper)
    29% identity, 72% coverage of query (80.9 bits)

7oz1A Cryo-em structure of abcg1 e242q mutant with atp and cholesteryl hemisuccinate bound
    29% identity, 72% coverage of query (80.5 bits)

1ji0A / Q9X0M3 Crystal structure analysis of the abc transporter from thermotoga maritima
    28% identity, 72% coverage of query (79.7 bits)

5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
    29% identity, 79% coverage of query (79.7 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    29% identity, 70% coverage of query (79.7 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    28% identity, 70% coverage of query (79.3 bits)

8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
    30% identity, 76% coverage of query (78.6 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    25% identity, 71% coverage of query (78.2 bits)

6xgyA Crystal structure of e. Coli mlafb abc transport subunits in the dimeric state
    30% identity, 71% coverage of query (77.8 bits)

7ch6C / P63386 Cryo-em structure of e.Coli mlafeb with amppnp (see paper)
    30% identity, 71% coverage of query (77.8 bits)

RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
    25% identity, 71% coverage of query (77.4 bits)

7cgnB The overall structure of the mlafedb complex in atp-bound eqtall conformation (mutation of e170q on mlaf)
    30% identity, 71% coverage of query (76.6 bits)

8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    30% identity, 74% coverage of query (76.6 bits)

ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
    30% identity, 70% coverage of query (76.3 bits)

6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
    29% identity, 71% coverage of query (75.5 bits)

3j5sD / P0A9W3 Etta binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics (see paper)
    29% identity, 72% coverage of query (74.7 bits)

YjjK / b4391 energy-dependent translational throttle protein EttA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ETTA_ECOLI / P0A9W3 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli (strain K12) (see 2 papers)
CH_004211 ABC transporter, ATP-binding protein YjiK from Escherichia coli K12 (see paper)
    29% identity, 72% coverage of query (74.3 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    27% identity, 70% coverage of query (72.0 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    27% identity, 70% coverage of query (72.0 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    27% identity, 70% coverage of query (72.0 bits)

ETTA_ECOL6 / A0A0H2VFI8 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
    29% identity, 72% coverage of query (71.6 bits)

8ipsA / P23886 Cryo-em structure of heme transporter cyddc from escherichia coli in the inward facing heme loading state (see paper)
    29% identity, 73% coverage of query (70.9 bits)

2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    26% identity, 71% coverage of query (70.1 bits)

7zdkC If(apo/asym) conformation of cyddc in amp-pnp(cydc)/amp-pnp(cydd) bound state (dataset-8)
    29% identity, 73% coverage of query (68.9 bits)

7zdfC If(heme/confined) conformation of cyddc in amp-pnp(cydd) bound state (dataset-4)
    29% identity, 73% coverage of query (68.9 bits)

7zdaC If(apo/asym) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
    29% identity, 73% coverage of query (68.9 bits)

4hluC / Q9X1Z1 Structure of the ecfa-a' heterodimer bound to adp (see paper)
    29% identity, 71% coverage of query (68.9 bits)

4zirB Crystal structure of ecfaa' heterodimer bound to amppnp
    29% identity, 71% coverage of query (68.6 bits)

7zdtC Occ(apo/return) conformation of cyddc mutant (e500q.C) in atp(cydc) bound state (dataset-18)
    28% identity, 73% coverage of query (67.8 bits)

7vfiA Cryo-em structure of the mouse tapl (9mer-peptide bound)
    27% identity, 71% coverage of query (62.4 bits)

7v5cA / Q9JJ59 Cryo-em structure of the mouse abcb9 (adp.Bef3-bound) (see paper)
    27% identity, 71% coverage of query (62.4 bits)

8g4cB / O34697 Bceabs atpgs high res tm (see paper)
    23% identity, 78% coverage of query (61.6 bits)

ABCB9_HUMAN / Q9NP78 ABC-type oligopeptide transporter ABCB9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL; EC 7.4.2.6 from Homo sapiens (Human) (see 16 papers)
Q9NP78 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see 2 papers)
TC 3.A.1.209.2 / Q9NP78 Homodimeric transporter ABCB9 or TAPL. Transports a broad spectrum of peptides (low affinity) from the cytosol to the lysosomal lumen. It exists in two forms (812 aas and 1257 aas). The latter full length protein confers resistance to taxanes and anthracyclines (Kawanobe et al., 2012). Resistance and transport were demonstrated for paclitaxel and docetaxel. TapL transports a broad range of peptides of 6-60aas (23aas optimal). It has also been detected in the ER. It is stabilized by interaction with LAMP-1 and LAMP-2 (see 9.A.16) from Homo sapiens (see 18 papers)
    26% identity, 71% coverage of query (61.2 bits)

6p6jA / Q1RAG2 Structure of ybtpq importer with substrate ybt-fe bound (see paper)
    28% identity, 71% coverage of query (59.3 bits)

7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
    26% identity, 71% coverage of query (55.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory