Searching for up to 100 curated homologs for CCNA_01572 FitnessBrowser__Caulo:CCNA_01572 (224 a.a.)
Found high-coverage hits (≥70%) to 18 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
aqpS / Q92R43 aquaglyceroporin from Rhizobium meliloti (strain 1021) (see 2 papers)
AQPS_RHIME / Q92R43 Aquaglyceroporin AqpS from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
TC 1.A.8.12.10 / Q92R43 Arsenite export pore, AqpS (see paper)
58% identity, 98% coverage of query (226 bits)
TC 1.A.8.12.1 / P08995 Nodulin-26 aquaporin and glycerol facilitator, NIP (de Paula Santos Martins et al. 2015). Transports NH3 5-fold better than water in Hg2+-sensitive fashion from Glycine max (Soybean) (see 3 papers)
33% identity, 96% coverage of query (74.3 bits)
P08995 Nodulin-26; N-26 from Glycine max (Soybean) (Glycine hispida)
33% identity, 96% coverage of query (74.3 bits)
NIP2-1 / Q6Z2T3 aquaporin NIP2-1 from Oryza sativa subsp. japonica (see 7 papers)
NIP21_ORYSJ / Q6Z2T3 Aquaporin NIP2-1; Low silicon protein 1; NOD26-like intrinsic protein 2-1; OsNIP2;1; Silicon influx transporter LSI1 from Oryza sativa subsp. japonica (Rice) (see 6 papers)
TC 1.A.8.12.2 / Q6Z2T3 The silicon (silicic acid) (undissociated form) transporter, Lsi1 (Ma et al., 2007a, b; Mitani et al., 2008). The barley orthologue Lsi1 (also called NIP2-1) is also a silicon (silicic acid) uptake channel (Chiba et al., 2009). Rice Lsi1 also transports arsenite and pentavalent mono and dimethyl arsenite (Li et al., 2009). In addition to silicon (Si), selenite (Se) uptake is mediated by Lsi1, also called NIP2;1 from Oryza sativa (Rice) (see 6 papers)
NIP2-1 / GI|90855460 aquaporin NIP2-1 from Oryza sativa (japonica cultivar-group) (see paper)
31% identity, 97% coverage of query (67.8 bits)
NIP1 / CAD67694.1 Nod26-like protein from Cucurbita pepo (see paper)
33% identity, 82% coverage of query (65.5 bits)
Build an alignment for CCNA_01572 and 5 homologs with ≥ 30% identity
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PIP28_ARATH / Q9ZVX8 Probable aquaporin PIP2-8; Plasma membrane intrinsic protein 2-8; AtPIP2;8; Plasma membrane intrinsic protein 3b; PIP3b from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 1.A.8.11.6 / Q9ZVX8 Aquaporin PIP2-8 (Plasma membrane intrinsic protein 2-8) (AtPIP2;8) (Plasma membrane intrinsic protein 3b) (PIP3b) from Arabidopsis thaliana (see 4 papers)
29% identity, 95% coverage of query (62.8 bits)
NIP22_ORYSJ / Q67WJ8 Aquaporin NIP2-2; Low silicon protein 6; NOD26-like intrinsic protein 2-2; OsNIP2;2 from Oryza sativa subsp. japonica (Rice) (see 3 papers)
TC 1.A.8.12.5 / Q67WJ8 The silicon (silicic acid) transporter, Nip2-2 (Nip2;2) (Mitani et al., 2008). Also transports arsenite from Oryza sativa subsp. japonica (Rice) (see 5 papers)
29% identity, 94% coverage of query (61.2 bits)
PIP28_ORYSJ / Q7Y1E6 Probable aquaporin PIP2-8; OsPIP2;8; Plasma membrane intrinsic protein 2-8 from Oryza sativa subsp. japonica (Rice) (see paper)
30% identity, 79% coverage of query (60.5 bits)
PIP27_MUSAC / A0A6M3QG69 Aquaporin PIP2-7; PIP2-6-like protein PIP2-7; Plasma membrane intrinsic protein 2-7; MaPIP2-7; MaPIP2;7 from Musa acuminata (Banana) (Musa cavendishii) (see 2 papers)
29% identity, 95% coverage of query (60.5 bits)
NIP12_ARATH / Q8LFP7 Aquaporin NIP1-2; NOD26-like intrinsic protein 1-2; AtNIP1;2; Nodulin-26-like major intrinsic protein 2; NodLikeMip2; Protein NLM2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 1.A.8.12.7 / Q8LFP7 Aquaporin NIP1-2 (NOD26-like intrinsic protein 1-2) (AtNIP1;2) (Nodulin-26-like major intrinsic protein 2) (NodLikeMip2) (Protein NLM2) from Arabidopsis thaliana (see 5 papers)
nlm2 / CAC14597.1 aquaglyceroporin from Arabidopsis thaliana (see paper)
31% identity, 96% coverage of query (58.9 bits)
AQPA_DICDI / Q9U8P7 Aquaporin A from Dictyostelium discoideum (Social amoeba) (see paper)
31% identity, 97% coverage of query (55.1 bits)
BIB_DROME / P23645 Neurogenic protein big brain from Drosophila melanogaster (Fruit fly) (see 6 papers)
TC 1.A.8.8.3 / P23645 The BIB aquaporin of D. melanogaster (transports ions by a channel mechanism involving E71 in TMS1) (Yool, 2007) from Drosophila melanogaster (Fruit fly) (see 9 papers)
bib / RF|NP_476837.1 neurogenic protein big brain from Drosophila melanogaster (see paper)
29% identity, 79% coverage of query (53.9 bits)
GLPF6_LACPL / F9UUD2 Glycerol uptake facilitator protein-like 6 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
33% identity, 91% coverage of query (53.1 bits)
AQP4_MOUSE / P55088 Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4 from Mus musculus (Mouse) (see 11 papers)
25% identity, 95% coverage of query (48.5 bits)
5dyeD / P55064 Crystal structure of the full length s156e mutant of human aquaporin 5 (see paper)
29% identity, 78% coverage of query (47.8 bits)
AQP5_HUMAN / P55064 Aquaporin-5; AQP-5 from Homo sapiens (Human) (see 6 papers)
TC 1.A.8.8.9 / P55064 Aquaporin 5 (x-ray structure at 2.0 Å resolution (PDB# 3D9S) is available) (Horsefield et al., 2008). Aqp5 is a marker for proliferation and migration of human breast cancer cells (Jung et al., 2011). Plays a role in chronic obstructive pulmonary diseases (COPD) from Homo sapiens (see 2 papers)
30% identity, 76% coverage of query (47.0 bits)
AQP4_RAT / P47863 Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4 from Rattus norvegicus (Rat) (see 7 papers)
24% identity, 79% coverage of query (46.6 bits)
TIP21_ARATH / Q41951 Aquaporin TIP2-1; Delta-tonoplast intrinsic protein; Delta-TIP; Tonoplast intrinsic protein 2-1; AtTIP2;1 from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
TC 1.A.8.10.10 / Q41951 Aquaporin TIP2-1 (Delta-tonoplast intrinsic protein) (Delta-TIP) (Tonoplast intrinsic protein 2-1) (AtTIP2;1) (Daniels et al. 1996). Transports water and ammonia, and can be activated by mercury (Kirscht et al. 2016). The 3-d structure is known to 1.2Å resolution (Kirscht et al. 2016). It may participate in vacuolar compartmentation and detoxification of ammonium from Arabidopsis thaliana (see 10 papers)
AAC49281.1 delta tonoplast integral protein from Arabidopsis thaliana (see paper)
28% identity, 79% coverage of query (42.4 bits)
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Lawrence Berkeley National Laboratory